Mutated MCM9 is associated with predisposition to hereditary mixed polyposis and colorectal cancer in addition to primary ovarian failure

Cancer Genetics

Volumn 208, Issue 12, 2015, Pages 621-624

  Goldberg, Yael ^a   Halpern, Naama ^a   Hubert, Ayala ^a   Adler, Samuel N ^b   Cohen, Sherri ^a   Plesser Duvdevani, Morasha ^a   Pappo, Orit ^a   Shaag, Avraham ^a   Meiner, Vardiella ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b SHAARE ZEDEK MEDICAL CENTER   (Israel)

Author keywords

Chromosomal instability; Colorectal cancer; DNA helicase MCM9; Hereditary mixed polyposis; Primary ovarian failure

Indexed keywords

CYTOSINE; GLUTAMIC ACID; GUANINE; LYSINE; MINICHROMOSOME MAINTENANCE PROTEIN 9; MCM9 PROTEIN, HUMAN; MINICHROMOSOME MAINTENANCE PROTEIN;

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CANCER SUSCEPTIBILITY; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; EXOME; FAMILIAL CANCER; FAMILY STUDY; FEMALE; GASTROINTESTINAL POLYPOSIS; GENE DELETION; GENE INSERTION; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENE TARGETING; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENOME ANALYSIS; HEREDITARY MIXED POLYPOSIS; HOMOZYGOSITY; HOMOZYGOTE; HUMAN; HUMAN GENOME; HUMAN TISSUE; HYPERGONADOTROPIC HYPOGONADISM; MALE; MCM9 GENE; MIDDLE AGED; ONSET AGE; OVARY INSUFFICIENCY; PHENOTYPE; PRIORITY JOURNAL; VERY ELDERLY; CASE REPORT; CHROMOSOMAL INSTABILITY; COLON POLYPOSIS; COLORECTAL TUMOR; COMPLICATION; CONSANGUINITY; GENETICS; MUTATION; PEDIGREE; PREMATURE OVARIAN FAILURE;

ADENOMATOUS POLYPOSIS COLI; ADULT; CHROMOSOMAL INSTABILITY; COLORECTAL NEOPLASMS; CONSANGUINITY; FEMALE; HUMANS; MINICHROMOSOME MAINTENANCE PROTEINS; MUTATION; PEDIGREE; PRIMARY OVARIAN INSUFFICIENCY;

EID: 84949673296     PISSN: 22107762     EISSN: 22107770     Source Type: Journal    
DOI: 10.1016/j.cancergen.2015.10.001     Document Type: Article

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