Transcriptome sequencing reveals CHD1 as a novel fusion partner of RUNX1 in acute myeloid leukemia with t(5;21)(q21;q22)

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Yao, Hong ^a   Pan, Jinlan ^a   Wu, Chunxiao ^a   Shen, Hongjie ^a   Xie, Jundan ^a   Wang, Qinrong ^a   Wen, Lijun ^a   Wang, Qian ^a   Ma, Liang ^a   Wu, Lili ^a   Ping, Nana ^a   Zhao, Yun ^b   Sun, Aining ^a   Chen, Suning ^a,b  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

Author keywords

Acute myeloid leukemia; CHD1; Fusion gene; RUNX1

Indexed keywords

CHROMODOMAIN HELICASE DNA BINDING PROTEIN 1; CYTARABINE; DNA BINDING PROTEIN; IDARUBICIN; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; CHD1 PROTEIN, HUMAN; DNA HELICASE; ONCOPROTEIN; TRANSCRIPTOME;

ACUTE MYELOBLASTIC LEUKEMIA; ADULT; ARTICLE; CASE REPORT; CHD1 GENE; CHROMOSOME TRANSLOCATION 21; CHROMOSOME TRANSLOCATION 5; FATIGUE; FEMALE; FEVER; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; GENE MUTATION; GENETIC PROCEDURES; GENETIC TRANSCRIPTION; HUMAN; KARYOTYPE 46,XX; LEUKEMIA RELAPSE; LEUKEMIA REMISSION; MIDDLE AGED; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; RUNX1 GENE; SEQUENCE ANALYSIS; TRANSCRIPTOME SEQUENCING; CHROMOSOME 21; CHROMOSOME 5; CHROMOSOME BREAKAGE; DNA SEQUENCE; GENE ORDER; GENE TRANSLOCATION; GENETICS; KARYOTYPING; LEUKEMIA, MYELOID, ACUTE;

CHROMOSOME BREAKPOINTS; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, PAIR 5; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA HELICASES; DNA-BINDING PROTEINS; FEMALE; GENE ORDER; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LEUKEMIA, MYELOID, ACUTE; MIDDLE AGED; ONCOGENE PROTEINS, FUSION; SEQUENCE ANALYSIS, DNA; TRANSCRIPTOME; TRANSLOCATION, GENETIC;

EID: 84949667517     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0353-x     Document Type: Article

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