Comparative blood transcriptome analysis in idiopathic and LRRK2 G2019S-associated Parkinson's disease

Neurobiology of Aging

Volumn 38, Issue , 2015, Pages 214.e1-214.e5

  Infante, Jon ^a,b   Prieto, Carlos ^c   Sierra, María ^a,b   Sánchez Juan, Pascual ^a,b   González Aramburu, Isabel ^a,b   Sánchez Quintana, Coro ^a   Berciano, José ^a,b   Combarros, Onofre ^a,b   Sainz, Jesús ^d  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^c UNIVERSITY OF SALAMANCA   (Spain)

^d University of Cantabria   (Spain)

Author keywords

Gene expression; LRRK2; Parkinson's disease; Peripheral blood; RNA seq; Trancriptome

Indexed keywords

COMPLEMENT; GLYCINE; LEUCINE RICH REPEAT KINASE 2; SERINE; TRANSCRIPTOME; LRRK2 PROTEIN, HUMAN; MESSENGER RNA;

ADULT; AGED; ARTICLE; ASYMPTOMATIC DISEASE; BLOOD ANALYSIS; BLOOD CLOTTING; CELL ADHESION; CELL LINEAGE; CLINICAL ARTICLE; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOME ANALYSIS; HEMATOPOIETIC CELL; HETEROZYGOTE; HUMAN; HUMAN GENOME; IDIOPATHIC DISEASE; LRRK2 GENE; MALE; MOLECULAR PATHOLOGY; PARKINSON DISEASE; PRIORITY JOURNAL; RNA ANALYSIS; RNA SEQUENCE; SYMPTOM; TRANSCRIPTOMICS; BLOOD; GENE EXPRESSION PROFILING; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MIDDLE AGED; MUTATION; SEQUENCE ANALYSIS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; COHORT STUDIES; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOME-WIDE ASSOCIATION STUDY; HETEROZYGOTE; HUMANS; LEUCINE-RICH REPEAT SERINE-THREONINE PROTEIN KINASE-2; MIDDLE AGED; MUTATION; PARKINSON DISEASE; RNA, MESSENGER; SEQUENCE ANALYSIS, RNA; TRANSCRIPTOME;

EID: 84949651389     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.10.026     Document Type: Article

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