-
1
-
-
42549123597
-
LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease
-
DOI 10.1111/j.1365-2990.2007.00888.x
-
J. Alegre-Abarrategui, O. Ansorge, M. Esiri, and R. Wade-Martins LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease Neuropathol. Appl. Neurobiol. 34 3 2008 272 283 (Pubitemid 351590862)
-
(2008)
Neuropathology and Applied Neurobiology
, vol.34
, Issue.3
, pp. 272-283
-
-
Alegre-Abarrategui, J.1
Ansorge, O.2
Esiri, M.3
Wade-Martins, R.4
-
2
-
-
1542399989
-
FatiGO: A web tool for finding significant associations of Gene Ontology terms with groups of genes
-
DOI 10.1093/bioinformatics/btg455
-
F. Al-Shahrour, R. Diaz-Uriarte, and J. Dopazo (FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes Bioinformatics 20 2004 578 580 (Pubitemid 38344339)
-
(2004)
Bioinformatics
, vol.20
, Issue.4
, pp. 578-580
-
-
Al-Shahrour, F.1
Diaz-Uriarte, R.2
Dopazo, J.3
-
3
-
-
34247354150
-
From genes to functional classes in the study of biological systems
-
F. Al-Shahrour, L. Arbiza, H. Dopazo, J. Huerta-Cepas, P. Minguez, D. Montaner, and J. Dopazo (From genes to functional classes in the study of biological systems BMC Bioinforma 8 2007 114
-
(2007)
BMC Bioinforma
, vol.8
, pp. 114
-
-
Al-Shahrour, F.1
Arbiza, L.2
Dopazo, H.3
Huerta-Cepas, J.4
Minguez, P.5
Montaner, D.6
Dopazo, J.7
-
4
-
-
33750443924
-
Morphological alterations of the synapses in the locus coeruleus in Parkinson's disease
-
DOI 10.1016/j.jns.2006.05.006, PII S0022510X06001973
-
S.J. Baloyannis, V. Costa, and I.S. Baloyannis Morphological alterations of the synapses in the locus coeruleus in Parkinson's disease J. Neurol. Sci. 248 1-2 2006 35 41 (Pubitemid 44647280)
-
(2006)
Journal of the Neurological Sciences
, vol.248
, Issue.1-2
, pp. 35-41
-
-
Baloyannis, S.J.1
Costa, V.2
Baloyannis, I.S.3
-
5
-
-
81955167469
-
Microarray expression analysis in idiopathic and LRRK2-associated Parkinson's disease
-
T. Botta-Orfila, E. Tolosa, E. Gelpi, A. Sanchez-Pla, M.J. Marti, F. Valldeoriola, M. Fernandez, F. Carmona, and M. Ezquerra Microarray expression analysis in idiopathic and LRRK2-associated Parkinson's disease Neurobiol. Dis. 45 1 2012 462 468
-
(2012)
Neurobiol. Dis.
, vol.45
, Issue.1
, pp. 462-468
-
-
Botta-Orfila, T.1
Tolosa, E.2
Gelpi, E.3
Sanchez-Pla, A.4
Marti, M.J.5
Valldeoriola, F.6
Fernandez, M.7
Carmona, F.8
Ezquerra, M.9
-
6
-
-
0023073288
-
Parkinson's disease and dementia: Norepinephrine and dopamine in locus ceruleus
-
R. Cash, T. Dennis, R. L'Heureux, R. Raisman, F. Javoy-Agid, and B. Scatton Parkinson's disease and dementia: norepinephrine and dopamine in locus ceruleus Neurology 37 1987 42 46 (Pubitemid 17230106)
-
(1987)
Neurology
, vol.37
, Issue.1
, pp. 42-46
-
-
Cash, R.1
Dennis, T.2
L'Heureux, R.3
-
8
-
-
19944431081
-
A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease
-
DOI 10.1016/S0140-6736(05)17829-5, PII S0140673605178295
-
A. Di Fonzo, C.F. Rohé, J. Ferreira, H.F. Chien, L. Vacca, F. Stocchi, L. Guedes, E. Fabrizio, M. Manfredi, N. Vanacore, S. Goldwurm, G. Breedveld, C. Sampaio, G. Meco, E. Barbosa, B.A. Oostra, V. Bonifati Italian Parkinson Genetics Network A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease Lancet 365 9457 2005 412 415 (Pubitemid 40179228)
-
(2005)
Lancet
, vol.365
, Issue.9457
, pp. 412-415
-
-
Di Fonzo, A.1
Rohe, C.F.2
Ferreira, J.3
Chien, H.F.4
Vacca, L.5
Stocchi, F.6
Guedes, L.7
Fabrizio, E.8
Manfredi, M.9
Vanacore, N.10
Goldwurm, S.11
Breedveld, G.12
Sampaio, C.13
Meco, G.14
Barbosa, E.15
Oostra, B.A.16
Bonifati, V.17
-
9
-
-
0036081355
-
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
-
R. Edgar, M. Domrachev, and A.E. Lash Gene Expression Omnibus: NCBI gene expression and hybridization array data repository Nucleic Acids Res. 30 1 2002 207 210 (Pubitemid 34679544)
-
(2002)
Nucleic Acids Research
, vol.30
, Issue.1
, pp. 207-210
-
-
Edgar, R.1
Domrachev, M.2
Lash, A.E.3
-
10
-
-
33645790701
-
LRRK2 expression linked to dopamine-innervated areas
-
D. Galter, M. Westerlund, A. Carmine, E. Lindqvist, O. Sydow, and L. Olson (LRRK2 expression linked to dopamine-innervated areas Ann. Neurol. 59 2006 714 719
-
(2006)
Ann. Neurol.
, vol.59
, pp. 714-719
-
-
Galter, D.1
Westerlund, M.2
Carmine, A.3
Lindqvist, E.4
Sydow, O.5
Olson, L.6
-
11
-
-
79955921784
-
Neuroinflammation and alpha-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease
-
H.M. Gao, F. Zhang, H. Zhou, W. Kam, B. Wilson, and J.S. Hong Neuroinflammation and alpha-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease Environ. Health Perspect. 119 2011 807 814
-
(2011)
Environ. Health Perspect.
, vol.119
, pp. 807-814
-
-
Gao, H.M.1
Zhang, F.2
Zhou, H.3
Kam, W.4
Wilson, B.5
Hong, J.S.6
-
12
-
-
19944432921
-
A common LRRK2 mutation in idiopathic Parkinson's disease
-
DOI 10.1016/S0140-6736(05)17830-1, PII S0140673605178301
-
W.P. Gilks, P.M. Abou-Sleiman, S. Gandhi, S. Jain, A. Singleton, A.J. Lees, K. Shaw, K.P. Bhatia, V. Bonifati, N.P. Quinn, J. Lynch, D.G. Healy, J.L. Holton, T. Revesz, and N.W. Wood A common LRRK2 mutation in idiopathic Parkinson's disease Lancet 365 9457 2005 415 416 (Pubitemid 40179229)
-
(2005)
Lancet
, vol.365
, Issue.9457
, pp. 415-416
-
-
Gilks, W.P.1
Abou-Sleiman, P.M.2
Gandhi, S.3
Jain, S.4
Singleton, A.5
Lees, A.J.6
Shaw, K.7
Bhatia, K.P.8
Bonifati, V.9
Quinn, N.P.10
Lynch, J.11
Healy, D.G.12
Holton, J.L.13
Revesz, T.14
Wood, N.W.15
-
13
-
-
77956646167
-
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
-
T.H. Hamza, C.P. Zabetian, A. Tenesa, A. Laederach, J. Montimurro, D. Yearout, D.M. Kay, K.F. Doheny, J. Paschall, E. Pugh, V.I. Kusel, R. Collura, J. Roberts, A. Griffith, A. Samii, W.K. Scott, J. Nutt, S.A. Factor, and H. Payami (Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease Nat. Genet. 42 2010 781 785
-
(2010)
Nat. Genet.
, vol.42
, pp. 781-785
-
-
Hamza, T.H.1
Zabetian, C.P.2
Tenesa, A.3
Laederach, A.4
Montimurro, J.5
Yearout, D.6
Kay, D.M.7
Doheny, K.F.8
Paschall, J.9
Pugh, E.10
Kusel, V.I.11
Collura, R.12
Roberts, J.13
Griffith, A.14
Samii, A.15
Scott, W.K.16
Nutt, J.17
Factor, S.A.18
Payami, H.19
-
14
-
-
34250199013
-
Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain
-
DOI 10.1016/j.brainres.2007.04.034, PII S0006899307008657
-
S. Higashi, S. Biskup, A.B. West, D. Trinkaus, V.L. Dawson, R.L. Faull, H.J. Waldvogel, H. Arai, T.M. Dawson, D.J. Moore, and P.C. Emson (Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain Brain Res. 1155 2007 208 219 (Pubitemid 46900930)
-
(2007)
Brain Research
, vol.1155
, Issue.1
, pp. 208-219
-
-
Higashi, S.1
Biskup, S.2
West, A.B.3
Trinkaus, D.4
Dawson, V.L.5
Faull, R.L.M.6
Waldvogel, H.J.7
Arai, H.8
Dawson, T.M.9
Moore, D.J.10
Emson, P.C.11
-
15
-
-
0023263919
-
Biochemical pathophysiology of Parkinson's disease
-
O. Hornykiewicz, and S.J. Kish (Biochemical pathophysiology of Parkinson's disease Adv. Neurol. 45 1987 19 34
-
(1987)
Adv. Neurol.
, vol.45
, pp. 19-34
-
-
Hornykiewicz, O.1
Kish, S.J.2
-
16
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
R.A. Irizarry, B. Hobbs, F. Collin, Y.D. Beazer-Barclay, K.J. Antonellis, U. Scherf, and T.P. Speed (Exploration, normalization, and summaries of high density oligonucleotide array probe level data Biostatistics 4 2003 249 264
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
Hobbs, B.2
Collin, F.3
Beazer-Barclay, Y.D.4
Antonellis, K.J.5
Scherf, U.6
Speed, T.P.7
-
17
-
-
34548853750
-
Wong WH (exon arrays provide accurate assessments of gene expression
-
K. Kapur, Y. Xing, and Z. Ouyang Wong WH (exon arrays provide accurate assessments of gene expression Genome Biol. 8 2007 R82
-
(2007)
Genome Biol.
, vol.8
, pp. 82
-
-
Kapur, K.1
Xing, Y.2
Ouyang, Z.3
-
18
-
-
79960981876
-
Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population
-
X. Liu, R. Cheng, M. Verbitsky, S. Kisselev, A. Browne, H. Mejia-Sanatana, E.D. Louis, L.J. Cote, H. Andrews, C. Waters, B. Ford, S. Frucht, S. Fahn, K. Marder, L.N. Clark, and J.H. Lee Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population BMC Med. Genet. 12 2011 104
-
(2011)
BMC Med. Genet.
, vol.12
, pp. 104
-
-
Liu, X.1
Cheng, R.2
Verbitsky, M.3
Kisselev, S.4
Browne, A.5
Mejia-Sanatana, H.6
Louis, E.D.7
Cote, L.J.8
Andrews, H.9
Waters, C.10
Ford, B.11
Frucht, S.12
Fahn, S.13
Marder, K.14
Clark, L.N.15
Lee, J.H.16
-
19
-
-
0021077736
-
The locus coeruleus and its possible role in ageing and degenerative disease of the human central nervous system
-
DOI 10.1016/0047-6374(83)90100-8
-
D.M. Mann The locus coeruleus and its possible role in ageing and degenerative disease of the human central nervous system Mech. Ageing Dev. 23 1983 73 94 (Pubitemid 14240536)
-
(1983)
Mechanisms of Ageing and Development
, vol.23
, Issue.1
, pp. 73-94
-
-
Mann, D.M.A.1
-
20
-
-
1942516961
-
Noradrenergic mechanisms in neurodegenerative diseases: A theory
-
DOI 10.1016/j.brainresrev.2004.02.002, PII S0165017304000165
-
M.R. Marien, F.C. Colpaert, and A.C. Rosenquist Noradrenergic mechanisms in neurodegenerative diseases: a theory Brain Res. Brain Res. Rev. 45 2004 38 78 (Pubitemid 38520015)
-
(2004)
Brain Research Reviews
, vol.45
, Issue.1
, pp. 38-78
-
-
Marien, M.R.1
Colpaert, F.C.2
Rosenquist, A.C.3
-
21
-
-
77954339096
-
Babelomics: An integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional profiling
-
I. Medina, J. Carbonell, L. Pulido, S.C. Madeira, S. Goetz, A. Conesa, J. Tarraga, A. Pascual-Montano, R. Nogales-Cadenas, J. Santoyo, F. Garcia, M. Marba, D. Montaner, and J. Dopazo Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional profiling Nucleic Acids Res. 38 2010 W210 W213
-
(2010)
Nucleic Acids Res.
, vol.38
-
-
Medina, I.1
Carbonell, J.2
Pulido, L.3
Madeira, S.C.4
Goetz, S.5
Conesa, A.6
Tarraga, J.7
Pascual-Montano, A.8
Nogales-Cadenas, R.9
Santoyo, J.10
Garcia, F.11
Marba, M.12
Montaner, D.13
Dopazo, J.14
-
22
-
-
33749463769
-
LRRK2 expression in normal and pathologic human brain and in human cell lines
-
DOI 10.1097/01.jnen.0000235121.98052.54, PII 0000507220061000000003
-
J. Miklossy, T. Arai, J.P. Guo, A. Klegeris, S. Yu, E.G. McGeer, and P.L. McGeer LRRK2 expression in normal and pathologic human brain and in human cell lines J. Neuropathol. Exp. Neurol. 65 2006 953 963 (Pubitemid 44521796)
-
(2006)
Journal of Neuropathology and Experimental Neurology
, vol.65
, Issue.10
, pp. 953-963
-
-
Miklossy, J.1
Arai, T.2
Guo, J.-P.3
Klegeris, A.4
Yu, S.5
McGeer, E.G.6
McGeer, P.L.7
-
23
-
-
19944432606
-
Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease
-
DOI 10.1016/S0140-6736(05)17828-3, PII S0140673605178283
-
W.C. Nichols, N. Pankratz, D. Hernandez, C. Paisán-Ruíz, S. Jain, C.A. Halter, V.E. Michaels, T. Reed, A. Rudolph, C.W. Shults, A. Singleton, T. Foroud Parkinson Study Group-PROGENI investigators Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease Lancet 365 9457 2005 410 412 (Pubitemid 40179227)
-
(2005)
Lancet
, vol.365
, Issue.9457
, pp. 410-412
-
-
Nichols, W.C.1
Pankratz, N.2
Hernandez, D.3
Paisan-Ruiz, C.4
Jain, S.5
Halter, C.A.6
Michaels, V.E.7
Reed, T.8
Rudolph, A.9
Shults, C.W.10
Singleton, A.11
Foroud, T.12
-
24
-
-
77956958953
-
Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy
-
L. Qian, P.M. Flood, and J.S. Hong (Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy J. Neural. Transm. 117 2010 971 979
-
(2010)
J. Neural. Transm.
, vol.117
, pp. 971-979
-
-
Qian, L.1
Flood, P.M.2
Hong, J.S.3
-
25
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
(Article3)
-
G.K. Smyth Linear models and empirical bayes methods for assessing differential expression in microarray experiments Stat. Appl. Genet. Mol. Biol. 3 2004 (Article3)
-
(2004)
Stat. Appl. Genet. Mol. Biol.
, vol.3
-
-
Smyth, G.K.1
-
26
-
-
75949087271
-
Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention
-
M.G. Tansey, and M.S. Goldberg (Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention Neurobiol. Dis. 37 2010 510 518
-
(2010)
Neurobiol. Dis.
, vol.37
, pp. 510-518
-
-
Tansey, M.G.1
Goldberg, M.S.2
-
27
-
-
79954992107
-
Hsp70 and its molecular role in nervous system diseases
-
G. Turturici, G. Sconzo, and F. Geraci (Hsp70 and its molecular role in nervous system diseases Biochem. Res. Int. 2011 2011 618127
-
(2011)
Biochem. Res. Int.
, vol.2011
, pp. 618127
-
-
Turturici, G.1
Sconzo, G.2
Geraci, F.3
-
28
-
-
77954127252
-
Neuroinflammation and the prospects for anti-inflammatory treatment of Parkinson's disease
-
P.S. Whitton Neuroinflammation and the prospects for anti-inflammatory treatment of Parkinson's disease Curr. Opin. Investig. Drugs 11 2010 788 794
-
(2010)
Curr. Opin. Investig. Drugs
, vol.11
, pp. 788-794
-
-
Whitton, P.S.1
|