The Inhibitory Receptor NKG2A Sustains Virus-Specific CD8+ T Cells in Response to a Lethal Poxvirus Infection

Immunity

Volumn 43, Issue 6, 2015, Pages 1112-1124

  Rapaport, Aaron S ^a   Schriewer, Jill ^b   Gilfillan, Susan ^a   Hembrador, Ed ^b   Crump, Ryan ^b   Plougastel, Beatrice F ^a   Wang, Yaming ^a   Le Friec, Gaelle ^a,d   Gao, Jian ^a   Cella, Marina ^a   Pircher, Hanspeter ^c   Yokoyama, Wayne M ^a   Buller, R Mark L ^b   Colonna, Marco ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF FREIBURG   (Germany)

^d GUY S HOSPITAL   (United Kingdom)

Author keywords

CD8+ T cell; Cytokine; Inhibitory receptor; NK cell; NKG2A; Virus

Indexed keywords

CD11B ANTIGEN; CD27 ANTIGEN; CD8 ANTIGEN; CD94 ANTIGEN; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2A; NATURAL KILLER CELL RECEPTOR NKG2C; NATURAL KILLER CELL RECEPTOR NKG2E; TRANSCRIPTOME; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY C;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CELL STIMULATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; DOWN REGULATION; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE LOCUS; HISTOPATHOLOGY; IN VIVO STUDY; LEUKOCYTE COUNT; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MALE; MICROARRAY ANALYSIS; MORBIDITY; MORTALITY; MOUSE; MOUSEPOX; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SEX DIFFERENCE; STEADY STATE; T LYMPHOCYTE ACTIVATION; UPREGULATION; VIRUS LOAD; VIRUS RESISTANCE; ANIMAL; C57BL MOUSE; CYTOTOXICITY; DISEASE MODEL; DNA MICROARRAY; IMMUNOLOGY; KNOCKOUT MOUSE; NATURAL KILLER CELL; POXVIRUS INFECTION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY, IMMUNOLOGIC; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY C; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POXVIRIDAE INFECTIONS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84949634220     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2015.11.005     Document Type: Article

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