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Volumn 34, Issue 50, 2015, Pages 6105-6114

The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN; TCFAP2C PROTEIN; UNCLASSIFIED DRUG; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, HUMAN; TCFAP2C PROTEIN, MOUSE; TRANSCRIPTION FACTOR AP 2;

EID: 84949591122     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2015.59     Document Type: Article
Times cited : (20)

References (42)
  • 1
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001; 98: 10869-10874.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3    Aas, T.4    Geisler, S.5    Johnsen, H.6
  • 3
    • 33744960226 scopus 로고    scopus 로고
    • Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
    • Carey LA, Perou CM, Livasy CA, Dressler LG, Cowan D, Conway K et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA 2006; 295: 2492-2502.
    • (2006) JAMA , vol.295 , pp. 2492-2502
    • Carey, L.A.1    Perou, C.M.2    Livasy, C.A.3    Dressler, L.G.4    Cowan, D.5    Conway, K.6
  • 4
    • 67650252530 scopus 로고    scopus 로고
    • Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery
    • Kao J, Salari K, Bocanegra M, Choi YL, Girard L, Gandhi J et al. Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery. PLoS One 2009; 4: e6146.
    • (2009) PLoS One , vol.4 , pp. e6146
    • Kao, J.1    Salari, K.2    Bocanegra, M.3    Choi, Y.L.4    Girard, L.5    Gandhi, J.6
  • 5
    • 0032445260 scopus 로고    scopus 로고
    • HER-2/neu as a predictive marker of response to breast cancer therapy
    • Pegram MD, Pauletti G, Slamon DJ. HER-2/neu as a predictive marker of response to breast cancer therapy. Breast Cancer Res Treat 1998; 52: 65-77.
    • (1998) Breast Cancer Res Treat , vol.52 , pp. 65-77
    • Pegram, M.D.1    Pauletti, G.2    Slamon, D.J.3
  • 6
    • 84902011260 scopus 로고    scopus 로고
    • Impact of neoadjuvant single or dual HER2 inhibition and chemotherapy backbone upon pathological complete response in operable and locally advanced breast cancer: Sensitivity analysis of randomized trials
    • Bria E, Carbognin L, Furlanetto J, Pilotto S, Bonomi M, Guarneri V et al. Impact of neoadjuvant single or dual HER2 inhibition and chemotherapy backbone upon pathological complete response in operable and locally advanced breast cancer: sensitivity analysis of randomized trials. Cancer Treat Rev 2014; 40: 847-856.
    • (2014) Cancer Treat Rev , vol.40 , pp. 847-856
    • Bria, E.1    Carbognin, L.2    Furlanetto, J.3    Pilotto, S.4    Bonomi, M.5    Guarneri, V.6
  • 7
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2011; 121: 2750-2767.
    • (2011) J Clin Invest , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3    Sanders, M.E.4    Chakravarthy, A.B.5    Shyr, Y.6
  • 8
    • 83455236666 scopus 로고    scopus 로고
    • Basal breast cancer: A complex and deadly molecular subtype
    • Bertucci F, Finetti P, Birnbaum D. Basal breast cancer: a complex and deadly molecular subtype. Curr Mol Med 2012; 12: 96-110.
    • (2012) Curr Mol Med , vol.12 , pp. 96-110
    • Bertucci, F.1    Finetti, P.2    Birnbaum, D.3
  • 9
    • 36549045999 scopus 로고    scopus 로고
    • Immunohistochemical expression patterns of AP2alpha and AP2gamma in the developing fetal human breast
    • Friedrichs N, Steiner S, Buettner R, Knoepfle G. Immunohistochemical expression patterns of AP2alpha and AP2gamma in the developing fetal human breast. Histopathology 2007; 51: 814-823.
    • (2007) Histopathology , vol.51 , pp. 814-823
    • Friedrichs, N.1    Steiner, S.2    Buettner, R.3    Knoepfle, G.4
  • 10
    • 0037376265 scopus 로고    scopus 로고
    • Overexpression of transcription factor AP-2alpha suppresses mammary gland growth and morphogenesis
    • Zhang J, Brewer S, Huang J, Williams T. Overexpression of transcription factor AP-2alpha suppresses mammary gland growth and morphogenesis. Dev Biol 2003; 256: 127-145.
    • (2003) Dev Biol , vol.256 , pp. 127-145
    • Zhang, J.1    Brewer, S.2    Huang, J.3    Williams, T.4
  • 11
    • 0142120585 scopus 로고    scopus 로고
    • Transcription factor AP-2gamma stimulates proliferation and apoptosis and impairs differentiation in a transgenic model
    • Jager R, Werling U, Rimpf S, Jacob A, Schorle H. Transcription factor AP-2gamma stimulates proliferation and apoptosis and impairs differentiation in a transgenic model. Mol Cancer Res 2003; 1: 921-929.
    • (2003) Mol Cancer Res , vol.1 , pp. 921-929
    • Jager, R.1    Werling, U.2    Rimpf, S.3    Jacob, A.4    Schorle, H.5
  • 12
    • 0036333999 scopus 로고    scopus 로고
    • Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development
    • Auman HJ, Nottoli T, Lakiza O, Winger Q, Donaldson S, Williams T. Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development. Development 2002; 129: 2733-2747.
    • (2002) Development , vol.129 , pp. 2733-2747
    • Auman, H.J.1    Nottoli, T.2    Lakiza, O.3    Winger, Q.4    Donaldson, S.5    Williams, T.6
  • 13
    • 77149180386 scopus 로고    scopus 로고
    • Loss of transcription factor AP-2gamma/TFAP2C impairs branching morphogenesis of the murine mammary gland
    • Jager R, Schafer S, Hau-Liersch M, Schorle H. Loss of transcription factor AP-2gamma/TFAP2C impairs branching morphogenesis of the murine mammary gland. Dev Dyn 2010; 239: 1027-1033.
    • (2010) Dev Dyn , vol.239 , pp. 1027-1033
    • Jager, R.1    Schafer, S.2    Hau-Liersch, M.3    Schorle, H.4
  • 14
  • 15
    • 34548797209 scopus 로고    scopus 로고
    • TFAP2C controls hormone response in breast cancer cells through multiple pathways of estrogen signaling
    • Woodfield GW, Horan AD, Chen Y, Weigel RJ. TFAP2C controls hormone response in breast cancer cells through multiple pathways of estrogen signaling. Cancer Res 2007; 67: 8439-8443.
    • (2007) Cancer Res , vol.67 , pp. 8439-8443
    • Woodfield, G.W.1    Horan, A.D.2    Chen, Y.3    Weigel, R.J.4
  • 17
    • 0029910361 scopus 로고    scopus 로고
    • A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma
    • Bosher JM, Totty NF, Hsuan JJ, Williams T, Hurst HC. A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma. Oncogene 1996; 13: 1701-1707.
    • (1996) Oncogene , vol.13 , pp. 1701-1707
    • Bosher, J.M.1    Totty, N.F.2    Hsuan, J.J.3    Williams, T.4    Hurst, H.C.5
  • 18
    • 25144516724 scopus 로고    scopus 로고
    • Distal ERBB2 promoter fragment displays specific transcriptional and nuclear binding activities in ERBB2 overexpressing breast cancer cells
    • Delacroix L, Begon D, Chatel G, Jackers P, Winkler R. Distal ERBB2 promoter fragment displays specific transcriptional and nuclear binding activities in ERBB2 overexpressing breast cancer cells. DNA Cell Biol 2005; 24: 582-594.
    • (2005) DNA Cell Biol , vol.24 , pp. 582-594
    • Delacroix, L.1    Begon, D.2    Chatel, G.3    Jackers, P.4    Winkler, R.5
  • 19
    • 69949116815 scopus 로고    scopus 로고
    • Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells
    • Ailan H, Xiangwen X, Daolong R, Lu G, Xiaofeng D, Xi Q et al. Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells. BMC Cancer 2009; 9: 279.
    • (2009) BMC Cancer , vol.9 , pp. 279
    • Ailan, H.1    Xiangwen, X.2    Daolong, R.3    Lu, G.4    Xiaofeng, D.5    Xi, Q.6
  • 20
    • 44849129793 scopus 로고    scopus 로고
    • The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors
    • Allouche A, Nolens G, Tancredi A, Delacroix L, Mardaga J, Fridman V et al. The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors. Breast Cancer Res 2008; 10: R9.
    • (2008) Breast Cancer Res , vol.10 , pp. R9
    • Allouche, A.1    Nolens, G.2    Tancredi, A.3    Delacroix, L.4    Mardaga, J.5    Fridman, V.6
  • 21
    • 84894570741 scopus 로고    scopus 로고
    • Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies
    • Shiu KK, Wetterskog D, Mackay A, Natrajan R, Lambros M, Sims D et al. Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies. Oncogene 2014; 33: 619-631.
    • (2014) Oncogene , vol.33 , pp. 619-631
    • Shiu, K.K.1    Wetterskog, D.2    Mackay, A.3    Natrajan, R.4    Lambros, M.5    Sims, D.6
  • 22
    • 0032403128 scopus 로고    scopus 로고
    • Expression of AP-2 transcription factors in human breast cancer correlates with the regulation of multiple growth factor signalling pathways
    • Turner BC, Zhang J, Gumbs AA, Maher MG, Kaplan L, Carter D et al. Expression of AP-2 transcription factors in human breast cancer correlates with the regulation of multiple growth factor signalling pathways. Cancer Res 1998; 58: 5466-5472.
    • (1998) Cancer Res , vol.58 , pp. 5466-5472
    • Turner, B.C.1    Zhang, J.2    Gumbs, A.A.3    Maher, M.G.4    Kaplan, L.5    Carter, D.6
  • 25
    • 39049150399 scopus 로고    scopus 로고
    • Comparison of expression profiles of metastatic versus primary mammary tumors in MMTV-Wnt-1 and MMTV-Neu transgenic mice
    • Huang S, Chen Y, Podsypanina K, Li Y. Comparison of expression profiles of metastatic versus primary mammary tumors in MMTV-Wnt-1 and MMTV-Neu transgenic mice. Neoplasia 2008; 10: 118-124.
    • (2008) Neoplasia , vol.10 , pp. 118-124
    • Huang, S.1    Chen, Y.2    Podsypanina, K.3    Li, Y.4
  • 26
    • 0027996817 scopus 로고
    • The 5' enhancer of the mouse mammary tumor virus long terminal repeat contains a functional AP-2 element
    • Mellentin-Michelotti J, John S, Pennie WD, Williams T, Hager GL. The 5' enhancer of the mouse mammary tumor virus long terminal repeat contains a functional AP-2 element. J Biol Chem 1994; 269: 31983-31990.
    • (1994) J Biol Chem , vol.269 , pp. 31983-31990
    • Mellentin-Michelotti, J.1    John, S.2    Pennie, W.D.3    Williams, T.4    Hager, G.L.5
  • 27
    • 33751328082 scopus 로고    scopus 로고
    • ErbB receptors: New insights on mechanisms and biology
    • Linggi B, Carpenter G. ErbB receptors: new insights on mechanisms and biology. Trends Cell Biol 2006; 16: 649-656.
    • (2006) Trends Cell Biol , vol.16 , pp. 649-656
    • Linggi, B.1    Carpenter, G.2
  • 28
    • 0030697807 scopus 로고    scopus 로고
    • PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner
    • Bos M, Mendelsohn J, Kim YM, Albanell J, Fry DW, Baselga J. PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner. Clin Cancer Res 1997; 3: 2099-2106.
    • (1997) Clin Cancer Res , vol.3 , pp. 2099-2106
    • Bos, M.1    Mendelsohn, J.2    Kim, Y.M.3    Albanell, J.4    Fry, D.W.5    Baselga, J.6
  • 29
    • 77956218241 scopus 로고    scopus 로고
    • BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
    • Molyneux G, Geyer FC, Magnay FA, McCarthy A, Kendrick H, Natrajan R et al. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell 2010; 7: 403-417.
    • (2010) Cell Stem Cell , vol.7 , pp. 403-417
    • Molyneux, G.1    Geyer, F.C.2    Magnay, F.A.3    McCarthy, A.4    Kendrick, H.5    Natrajan, R.6
  • 30
    • 84874768475 scopus 로고    scopus 로고
    • Multipotent PI-MECs are the true targets of MMTV-neu tumorigenesis
    • Wagner KU, Booth BW, Boulanger CA, Smith GH. Multipotent PI-MECs are the true targets of MMTV-neu tumorigenesis. Oncogene 2013; 32: 1338.
    • (2013) Oncogene , vol.32 , pp. 1338
    • Wagner, K.U.1    Booth, B.W.2    Boulanger, C.A.3    Smith, G.H.4
  • 31
    • 72749103664 scopus 로고    scopus 로고
    • Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis
    • Visvader JE. Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis. Genes Dev 2009; 23: 2563-2577.
    • (2009) Genes Dev , vol.23 , pp. 2563-2577
    • Visvader, J.E.1
  • 32
    • 84877577009 scopus 로고    scopus 로고
    • Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages
    • Sale S, Lafkas D, Artavanis-Tsakonas S. Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages. Nat Cell Biol 2013; 15: 451-460.
    • (2013) Nat Cell Biol , vol.15 , pp. 451-460
    • Sale, S.1    Lafkas, D.2    Artavanis-Tsakonas, S.3
  • 34
    • 65549098841 scopus 로고    scopus 로고
    • Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer
    • Corkery B, Crown J, Clynes M, O'Donovan N. Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer. Ann Oncol 2009; 20: 862-867.
    • (2009) Ann Oncol , vol.20 , pp. 862-867
    • Corkery, B.1    Crown, J.2    Clynes, M.3    O'Donovan, N.4
  • 35
    • 35348848403 scopus 로고    scopus 로고
    • Prognostic significance of overexpression and phosphorylation of epidermal growth factor receptor (EGFR) and the presence of truncated EGFRvIII in locoregionally advanced breast cancer
    • Nieto Y, Nawaz F, Jones RB, Shpall EJ, Nawaz S. Prognostic significance of overexpression and phosphorylation of epidermal growth factor receptor (EGFR) and the presence of truncated EGFRvIII in locoregionally advanced breast cancer. J Clin Oncol 2007; 25: 4405-4413.
    • (2007) J Clin Oncol , vol.25 , pp. 4405-4413
    • Nieto, Y.1    Nawaz, F.2    Jones, R.B.3    Shpall, E.J.4    Nawaz, S.5
  • 36
    • 79955088678 scopus 로고    scopus 로고
    • Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: Applications for diagnostics and targeted drug mechanism of action
    • DeFazio-Eli L, Strommen K, Dao-Pick T, Parry G, Goodman L, Winslow J. Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: applications for diagnostics and targeted drug mechanism of action. Breast Cancer Res 2011; 13: R44.
    • (2011) Breast Cancer Res , vol.13 , pp. R44
    • DeFazio-Eli, L.1    Strommen, K.2    Dao-Pick, T.3    Parry, G.4    Goodman, L.5    Winslow, J.6
  • 38
    • 4644289313 scopus 로고    scopus 로고
    • A unique structure for epidermal growth factor receptor bound to GW572016 (lapatinib): Relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells
    • Wood ER, Truesdale AT, McDonald OB, Yuan D, Hassell A, Dickerson SH et al. A unique structure for epidermal growth factor receptor bound to GW572016 (lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells. Cancer Res 2004; 64: 6652-6659.
    • (2004) Cancer Res , vol.64 , pp. 6652-6659
    • Wood, E.R.1    Truesdale, A.T.2    McDonald, O.B.3    Yuan, D.4    Hassell, A.5    Dickerson, S.H.6
  • 39
    • 31944449735 scopus 로고    scopus 로고
    • AP-2alpha: A regulator of EGF receptor signaling and proliferation in skin epidermis
    • Wang X, Bolotin D, Chu DH, Polak L, Williams T, Fuchs E. AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis. J Cell Biol 2006; 172: 409-421.
    • (2006) J Cell Biol , vol.172 , pp. 409-421
    • Wang, X.1    Bolotin, D.2    Chu, D.H.3    Polak, L.4    Williams, T.5    Fuchs, E.6
  • 40
    • 84884670865 scopus 로고    scopus 로고
    • High TFAP2C/low CD44 expression is associated with an increased rate of pathologic complete response following neoadjuvant chemotherapy in breast cancer
    • Spanheimer PM, Askeland RW, Kulak MV, Wu T, Weigel RJ. High TFAP2C/low CD44 expression is associated with an increased rate of pathologic complete response following neoadjuvant chemotherapy in breast cancer. J Surg Res 2013; 184: 519-525.
    • (2013) J Surg Res , vol.184 , pp. 519-525
    • Spanheimer, P.M.1    Askeland, R.W.2    Kulak, M.V.3    Wu, T.4    Weigel, R.J.5
  • 41
    • 84883183615 scopus 로고    scopus 로고
    • Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer
    • Kulak MV, Cyr AR, Woodfield GW, Bogachek M, Spanheimer PM, Li T et al. Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer. Oncogene 2013; 32: 4043-4051.
    • (2013) Oncogene , vol.32 , pp. 4043-4051
    • Kulak, M.V.1    Cyr, A.R.2    Woodfield, G.W.3    Bogachek, M.4    Spanheimer, P.M.5    Li, T.6
  • 42
    • 77957886554 scopus 로고    scopus 로고
    • Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells
    • Woodfield GW, Chen Y, Bair TB, Domann FE, Weigel RJ. Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells. Genes Chromosomes Cancer 2010; 49: 948-962.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 948-962
    • Woodfield, G.W.1    Chen, Y.2    Bair, T.B.3    Domann, F.E.4    Weigel, R.J.5


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