MicroRNA-138 regulates metastatic potential of bladder cancer through ZEB2

Cellular Physiology and Biochemistry

Volumn 37, Issue 6, 2015, Pages 2366-2374

  Sun, De Kang ^a   Wang, Jian Ming ^a   Zhang, Peng ^a   Wang, Yong Qiang ^a  

^a YANTAI YUHUANGDING HOSPITAL   (China)

Author keywords

Bladder cancer (BC); Cancer metastases; MiR 138; ZEB2

Indexed keywords

MICRORNA; MICRORNA 138; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZEB2; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; 3' UNTRANSLATED REGION; HOMEODOMAIN PROTEIN; MESSENGER RNA; MIRN138 MICRORNA, HUMAN; REPRESSOR PROTEIN; ZEB2 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ARTICLE; BINDING SITE; BIOINFORMATICS; BLADDER CANCER; BLADDER CANCER CELL LINE; BLADDER TISSUE; CANCER PROGNOSIS; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; METASTASIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; REGULATORY MECHANISM; TUMOR INVASION; BLADDER TUMOR; FEMALE; GENETICS; MALE; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; CELL LINE, TUMOR; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; MALE; MICRORNAS; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; REPRESSOR PROTEINS; RNA, MESSENGER; URINARY BLADDER NEOPLASMS;

EID: 84949579908     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000438590     Document Type: Article

References (25)

1. Jin Y, Lu J, Wen J, Shen Y, Wen X. Regulation of growth of human bladder cancer by mir-192. Tumour Biol 2015; 36: 3791-3797
2. Tan MY, Mu XY, Liu B, Wang Y, Bao ED, Qiu JX, Fan Y. Sumo-specific protease 2 suppresses cell migration and invasion through inhibiting the expression of mmp13 in bladder cancer cells. Cell Physiol Biochem 2013; 32: 542-548
3. Hu Q, Tong S, Zhao X, Ding W, Gou Y, Xu K, Sun C, Xia G. Periostin mediates tgf-beta-induced epithelial mesenchymal transition in prostate cancer cells. Cell Physiol Biochem 2015; 36: 799-809
4. Sa Y, Li C, Li H, Guo H. Timp-1 induces alpha-smooth muscle actin in fibroblasts to promote urethral scar formation. Cell Physiol Biochem 2015; 35: 2233-2243
5. Lan A, Qi Y, Du J. Akt2 mediates tgf-beta1-induced epithelial to mesenchymal transition by deactivating gsk3beta/snail signaling pathway in renal tubular epithelial cells. Cell Physiol Biochem 2014; 34: 368-382
6. Teng Y, Zhao L, Zhang Y, Chen W, Li X. Id-1, a protein repressed by mir-29b, facilitates the tgfbeta1-induced epithelial-mesenchymal transition in human ovarian cancer cells. Cell Physiol Biochem 2014; 33: 717-730
7. Guo Y, Lang X, Lu Z, Wang J, Li T, Liao Y, Jia C, Zhao W, Fang H. Mir-10b directly targets zeb1 and pik3ca to curb adenomyotic epithelial cell invasiveness via upregulation of e-cadherin and inhibition of akt phosphorylation. Cell Physiol Biochem 2015; 35: 2169-2180
8. Schmalhofer O, Brabletz S, Brabletz T. E-cadherin, beta-catenin, and zeb1 in malignant progression of cancer. Cancer Metastasis Rev 2009; 28: 151-166
9. Di Leva G, Croce CM. Mirna profiling of cancer. Curr Opin Genet Dev 2013; 23: 3-11
10. Pereira DM, Rodrigues PM, Borralho PM, Rodrigues CM. Delivering the promise of mirna cancer therapeutics. Drug Discov Today 2013; 18: 282-289
11. Mei Q, Li F, Quan H, Liu Y, Xu H. Busulfan inhibits growth of human osteosarcoma through mir-200 family micrornas in vitro and in vivo. Cancer Sci 2014; 105: 755-762
12. Wang F, Xiao W, Sun J, Han D, Zhu Y. Mirna-181c inhibits egfr-signaling-dependent mmp9 activation via suppressing akt phosphorylation in glioblastoma. Tumour Biol 2014; 35: 8653-8658
13. Liu G, Jiang C, Li D, Wang R, Wang W. Mirna-34a inhibits egfr-signaling-dependent mmp7 activation in gastric cancer. Tumour Biol 2014; 35: 9801-9806
14. Wu N, Zhang C, Bai C, Han YP, Li Q. Mir-4782-3p inhibited non-small cell lung cancer growth via usp14. Cell Physiol Biochem 2014; 33: 457-467
15. Mitomo S, Maesawa C, Ogasawara S, Iwaya T, Shibazaki M, Yashima-Abo A, Kotani K, Oikawa H, Sakurai E, Izutsu N, Kato K, Komatsu H, Ikeda K, Wakabayashi G, Masuda T. Downregulation of mir-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines. Cancer Sci 2008; 99: 280-286
16. Zhao X, Yang L, Hu J, Ruan J. Mir-138 might reverse multidrug resistance of leukemia cells. Leuk Res 2010; 34: 1078-1082
17. Liu X, Lv XB, Wang XP, Sang Y, Xu S, Hu K, Wu M, Liang Y, Liu P, Tang J, Lu WH, Feng QS, Chen LZ, Qian CN, Bei JX, Kang T, Zeng YX. Mir-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the ccnd1 oncogene. Cell Cycle 2012; 11: 2495-2506
18. Wang W, Zhao LJ, Tan YX, Ren H, Qi ZT. Mir-138 induces cell cycle arrest by targeting cyclin d3 in hepatocellular carcinoma. Carcinogenesis 2012; 33: 1113-1120
19. Liang CC, Park AY, Guan JL. In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2007; 2: 329-333
20. Simoes AE, Pereira DM, Gomes SE, Brito H, Carvalho T, French A, Castro RE, Steer CJ, Thibodeau SN, Rodrigues CM, Borralho PM. Aberrant mek5/erk5 signalling contributes to human colon cancer progression via nf-kappab activation. Cell Death Dis 2015; 6: e1718
21. Xu C, Fu H, Gao L, Wang L, Wang W, Li J, Li Y, Dou L, Gao X, Luo X, Jing Y, Chim CS, Zheng X, Yu L. Bcr-Abl/ gata1/mir-138 mini circuitry contributes to the leukemogenesis of chronic myeloid leukemia. Oncogene 2014; 33: 44-54
22. Long L, Huang G, Zhu H, Guo Y, Liu Y, Huo J. Down-regulation of mir-138 promotes colorectal cancer metastasis via directly targeting twist2. J Transl Med 2013; 11: 275
23. Zhang H, Zhang H, Zhao M, Lv Z, Zhang X, Qin X, Wang H, Wang S, Su J, Lv X, Liu H, Du W, Zhou W, Chen X, Fei K. Mir-138 inhibits tumor growth through repression of ezh2 in non-small cell lung cancer. Cell Physiol Biochem 2013; 31: 56-65
24. Gao Y, Fan X, Li W, Ping W, Deng Y, Fu X. Mir-138-5p reverses gefitinib resistance in non-small cell lung cancer cells via negatively regulating g protein-coupled receptor 124. Biochem Biophys Res Commun 2014; 446: 179-186
25. Liu X, Wang C, Chen Z, Jin Y, Wang Y, Kolokythas A, Dai Y, Zhou X. Microrna-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. Biochem J 2011; 440: 23-31