A polymeric nanoparticle formulation of curcumin in combination with sorafenib synergistically inhibits tumor growth and metastasis in an orthotopic model of human hepatocellular carcinoma

Biochemical and Biophysical Research Communications

Volumn 468, Issue 4, 2015, Pages 525-532

  Hu, Bo ^a   Sun, Ding ^a,c   Sun, Chao ^a   Sun, Yun Fan ^a   Sun, Hai Xiang ^a   Zhu, Qing Feng ^a,b   Yang, Xin Rong ^a   Gao, Ya Bo ^a   Tang, Wei Guo ^a   Fan, Jia ^a   Maitra, Anirban ^b   Anders, Robert A ^a,b   Xu, Yang ^a  

^a FUDAN UNIVERSITY   (China)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Curcumin; Hepatocellular carcinoma; MMP 9; NF B; Sorafenib

Indexed keywords

CD133 ANTIGEN; CURCUMIN; GELATINASE B; NANOPARTICLE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; SORAFENIB; SYNAPTOTAGMIN I; ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; NANOCAPSULE; NICOTINAMIDE; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL LINE; CANCER INHIBITION; CELL CYCLE ARREST; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG FORMULATION; DRUG POTENTIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LIVER CELL CARCINOMA; LUNG METASTASIS; MALE; METASTASIS; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; POLYMERIZATION; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; CARCINOMA, HEPATOCELLULAR; CHEMISTRY; DIFFUSION; DRUG EFFECTS; LIVER NEOPLASMS; NUDE MOUSE; PATHOLOGY; SECONDARY; TREATMENT OUTCOME; TUMOR CELL LINE; ULTRASTRUCTURE;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; DIFFUSION; DRUG SYNERGISM; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOCAPSULES; NIACINAMIDE; PHENYLUREA COMPOUNDS; POLYMERS; TREATMENT OUTCOME;

EID: 84949548035     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.10.031     Document Type: Article

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