Anastomotic leakage after curative rectal cancer resection has no impact on long-term survival: a propensity score analysis

International Journal of Colorectal Disease

Volumn 30, Issue 12, 2015, Pages 1667-1675

  Ebinger, Sabrina M ^a   Warschkow, René ^a,b   Tarantino, Ignazio ^b   Schmied, Bruno M ^a   Marti, Lukas ^a,c  

^a CANTONAL HOSPITAL ST GALLEN   (Switzerland)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Anastomotic leackage; Cancer specific survival; Overall survival; Propensity score matching; Rectal cancer resection

Indexed keywords

ADULT; AGED; ANASTOMOSIS LEAKAGE; ARTICLE; CANCER MORTALITY; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SPECIFIC SURVIVAL; CANCER SURGERY; CLINICAL ASSESSMENT; CONFIDENCE INTERVAL; CORRELATION ANALYSIS; FEMALE; FOLLOW UP; HAZARD RATIO; HUMAN; LONG TERM SURVIVAL; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROPENSITY SCORE; PROPORTIONAL HAZARDS MODEL; RECTUM CANCER; RETROSPECTIVE STUDY; RISK FACTOR; STATISTICAL ANALYSIS; TERTIARY CARE CENTER; ANASTOMOTIC LEAK; CANCER STAGING; MIDDLE AGED; MORTALITY; RECTAL NEOPLASMS; TREATMENT OUTCOME; TUMOR RECURRENCE;

AGED; ANASTOMOTIC LEAK; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROPENSITY SCORE; RECTAL NEOPLASMS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84949533958     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-015-2331-6     Document Type: Article

References (28)

1. Kim SH, Bae KB, Kim JM, Shin JH, An MS, Ha TG, Ryu SM, Kim KH, Kim TH, Choi CS, Shin JY, Oh M, Baek SH, Hong KH (2012) Oncologic outcomes and risk factors for recurrence after tumor-specific mesorectal excision of rectal cancer: 782 cases. J Korean Soc Coloproctol 28(2):100–107. doi:10.3393/jksc.2012.28.2.100
2. Chen ZH, Song XM, Chen SC, Li MZ, Li XX, Zhan WH, He YL (2012) Risk factors for adverse outcome in low rectal cancer. World J Gastroenterol 18(1):64–69. doi:10.3748/wjg.v18.i1.64
3. Reshef A, Lavery I, Kiran RP (2012) Factors associated with oncologic outcomes after abdominoperineal resection compared with restorative resection for low rectal cancer: patient- and tumor-related or technical factors only? Dis Colon Rectum 55(1):51–58. doi:10.1097/DCR.0b013e3182351c1f
4. Karanjia ND, Corder AP, Bearn P, Heald RJ (1994) Leakage from stapled low anastomosis after total mesorectal excision for carcinoma of the rectum. Br J Surg 81(8):1224–1226
5. Snijders HS, Wouters MW, van Leersum NJ, Kolfschoten NE, Henneman D, de Vries AC, Tollenaar RA, Bonsing BA (2012) Meta-analysis of the risk for anastomotic leakage, the postoperative mortality caused by leakage in relation to the overall postoperative mortality. Eur J Surg Oncol 38(11):1013–1019. doi:10.1016/j.ejso.2012.07.111
6. den Dulk M, Marijnen CA, Collette L, Putter H, Pahlman L, Folkesson J, Bosset JF, Rodel C, Bujko K, van de Velde CJ (2009) Multicentre analysis of oncological and survival outcomes following anastomotic leakage after rectal cancer surgery. Br J Surg 96(9):1066–1075. doi:10.1002/bjs.6694
7. Mirnezami A, Mirnezami R, Chandrakumaran K, Sasapu K, Sagar P, Finan P (2011) Increased local recurrence and reduced survival from colorectal cancer following anastomotic leak: systematic review and meta-analysis. Ann Surg 253(5):890–899. doi:10.1097/SLA.0b013e3182128929
8. Warschkow R, Steffen T, Thierbach J, Bruckner T, Lange J, Tarantino I (2011) Risk factors for anastomotic leakage after rectal cancer resection and reconstruction with colorectostomy. A retrospective study with bootstrap analysis. Ann Surg Oncol 18(10):2772–2782. doi:10.1245/s10434-011-1696-1
9. Sauer R, Becker H, Hohenberger W, Rodel C, Wittekind C, Fietkau R, Martus P, Tschmelitsch J, Hager E, Hess CF, Karstens JH, Liersch T, Schmidberger H, Raab R (2004) Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351(17):1731–1740. doi:10.1056/NEJMoa040694
10. Locker GY, Hamilton S, Harris J, Jessup JM, Kemeny N, Macdonald JS, Somerfield MR, Hayes DF, Bast RC Jr (2006) ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. J Clin Oncol 24(33):5313–5327. doi:10.1200/jco.2006.08.2644
11. Ishwaran H, Kogalur UB, Blackstone EH, Lauer MS (2008) Random survival forests. Ann Appl Stat 841–860. doi:10.1214/08-AOAS169
12. Joffe MM, Rosenbaum PR (1999) Invited commentary: propensity scores. Am J Epidemiol 150(4):327–333
13. Rubin DB (1997) Estimating causal effects from large data sets using propensity scores. Ann Intern Med 127(8 Pt 2):757–763
14. Rosenbaum PR (1987) Model-based direct adjustment. J Am Stat Assoc 82(398):387–394. doi:10.1080/01621459.1987.10478441
15. Hansen BB, Klopfer SO (2006) Optimal full matching and related designs via network flows. J Comput Graph Stat 15:609–627
16. Sekhon JS (2011) Multivariate and propensity score matching software with automated balance optimization: the matching package for R. J Stat Softw 42:1–52
17. Warschkow R, Guller U, Koberle D, Muller SA, Steffen T, Thurnheer M, Schmied BM, Tarantino I (2014) Perioperative blood transfusions do not impact overall and disease-free survival after curative rectal cancer resection: a propensity score analysis. Ann Surg 259(1):131–138. doi:10.1097/SLA.0b013e318287ab4d
18. Smith JD, Butte JM, Weiser MR, D’Angelica MI, Paty PB, Temple LK, Guillem JG, Jarnagin WR, Nash GM (2013) Anastomotic leak following low anterior resection in stage IV rectal cancer is associated with poor survival. Ann Surg Oncol 20(8):2641–2646. doi:10.1245/s10434-012-2854-9
19. Bertelsen CA, Andreasen AH, Jorgensen T, Harling H (2010) Anastomotic leakage after curative anterior resection for rectal cancer: short and long-term outcome. Colorectal Dis 12(7 Online):e76–81. doi:10.1111/j.1463-1318.2009.01935.x
20. Kim HJ, Huh JW, Kim HR, Kim YJ (2014) Oncologic impact of anastomotic leakage in rectal cancer surgery according to the use of fibrin glue: case–control study using propensity score matching method. Am J Surg 207(6):840–846. doi:10.1016/j.amjsurg.2013.07.047
21. Eberhardt JM, Kiran RP, Lavery IC (2009) The impact of anastomotic leak and intra-abdominal abscess on cancer-related outcomes after resection for colorectal cancer: a case control study. Dis Colon Rectum 52(3):380–386. doi:10.1007/DCR.0b013e31819ad488
22. Gong JP, Yang L, Huang XE, Sun BC, Zhou JN, Yu DS, Zhou X, Li DZ, Guan X, Wang DF (2014) Outcomes based on risk assessment of anastomotic leakage after rectal cancer surgery. Asian Pac J Cancer Prev 15(2):707–712
23. Kulu Y, Tarantio I, Warschkow R, Kny S, Schneider M, Schmied BM, Buchler MW, Ulrich A (2015) Anastomotic leakage is associated with impaired overall and disease-free survival after curative rectal cancer resection: a propensity score analysis. Ann Surg Oncol 22(6):2059–2067. doi:10.1245/s10434-014-4187-3
24. Quirke P, Steele R, Monson J, Grieve R, Khanna S, Couture J, O’Callaghan C, Myint AS, Bessell E, Thompson LC, Parmar M, Stephens RJ, Sebag-Montefiore D (2009) Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial. Lancet 373(9666):821–828. doi:10.1016/s0140-6736(09)60485-2
25. Dik VK, Aarts MJ, Van Grevenstein WM, Koopman M, Van Oijen MG, Lemmens VE, Siersema PD (2014) Association between socioeconomic status, surgical treatment and mortality in patients with colorectal cancer. Br J Surg 101(9):1173–1182. doi:10.1002/bjs.9555
26. Jung SH, Yu CS, Choi PW, Kim DD, Park IJ, Kim HC, Kim JC (2008) Risk factors and oncologic impact of anastomotic leakage after rectal cancer surgery. Dis Colon Rectum 51(6):902–908. doi:10.1007/s10350-008-9272-x
27. Sturmer T, Joshi M, Glynn RJ, Avorn J, Rothman KJ, Schneeweiss S (2006) A review of the application of propensity score methods yielded increasing use, advantages in specific settings, but not substantially different estimates compared with conventional multivariable methods. J Clin Epidemiol 59(5):437–447. doi:10.1016/j.jclinepi.2005.07.004
28. Singh PP, Zeng IS, Srinivasa S, Lemanu DP, Connolly AB, Hill AG (2014) Systematic review and meta-analysis of use of serum C-reactive protein levels to predict anastomotic leak after colorectal surgery. Br J Surg 101(4):339–346. doi:10.1002/bjs.9354