Risk factors and oncologic impact of anastomotic leakage after rectal cancer surgery

Diseases of the Colon and Rectum

Volumn 51, Issue 6, 2008, Pages 902-908

  Jung, Sang Hun ^a   Yu, Chang Sik ^a   Choi, Pyong Wha ^a   Kim, Dae Dong ^a   Park, In Ja ^a   Kim, Hee Cheol ^a   Kim, Jin Cheon ^a  

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

Anastomotic leakage; Rectal cancer surgery; Risk factor; Survival rate

Indexed keywords

ADULT; ANASTOMOSIS LEAKAGE; ANUS SPHINCTER; ARTICLE; CANCER INVASION; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; HAZARD RATIO; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; RECTUM CANCER; RECTUM RESECTION; RETROSPECTIVE STUDY; RISK FACTOR; SENESCENCE; SEX DIFFERENCE; SURGICAL TECHNIQUE; TUMOR LOCALIZATION; TUMOR VOLUME;

ANASTOMOSIS, SURGICAL; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PROPORTIONAL HAZARDS MODELS; RECTAL NEOPLASMS; RECURRENCE; RETROSPECTIVE STUDIES; RISK FACTORS; SURGICAL WOUND DEHISCENCE; SURVIVAL RATE;

EID: 44749085251     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/s10350-008-9272-x     Document Type: Article

References (33)

1. Rullier E, Laurent C, Garrelon JL, Michel P, Saric J, Parneix M. Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 1998;85:355-8.
2. Pakkastie TE, Luukkonen PE, Jarvinen HJ. Anastomotic leakage after anterior resection of the rectum. Eur J Surg 1994;160:293-300.
3. Paty PB, Enker WE, Cohen AM, Lauwers GY. Treatment of rectal cancer by low anterior resection with coloanal anastomosis. Ann Surg 1994;219:365-73.
4. Cohen Z, Myers E, Langer B, Taylor B, Railton RH, Jamieson C. Double-stapling technique for low anterior resection. Dis Colon Rectum 1983;26:231-5.
5. Heald RJ, Moran BJ, Ryall RD, Sexton R, MacFarlane JK. Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997. Arch Surg 1998;133:894-9.
6. Carlsen E, Schlichting E, Guldvog I, Johnson E, Heald RJ. Effect of the introduction of total mesorectal excision for the treatment of rectal cancer. Br J Surg 1998;85:526-9.
7. Yeh CY, Changchien CR, Wang JY, et al. Pelvic drainage and other risk factors for leakage after elective anterior resection in rectal cancer patients: a prospective study of 978 patients. Ann Surg 2005;241:9-13.
8. Karanjia ND, Corder AP, Bearn P, Heald RJ. Leakage from stapled low anastomosis after total mesorectal excision for carcinoma of the rectum. Br J Surg 1994;81:1224-6.
9. Law WL, Chu KW. Anterior resection for rectal cancer with mesorectal excision: a prospective evaluation of 622 patients. Ann Surg 2004;240:260-8.
10. Vignali A, Fazio VW, Lavery IC, et al. Factors associated with the occurrence of leaks in stapled rectal anastomoses: a review of 1,014 patients. J Am Coll Surg 1997;185:105-13.
11. Law WI, Chu KW, Ho JW, Chan CW. Risk factors for anastomotic leakage after low anterior resection with total mesorectal excision. Am J Surg 2000;179:92-6.
12. Pakkastie TE, Ovaska JT, Pekkala ES, Luukkonen PE, Jarvinen HJ. A randomised study of colostomies in low colorectal anastomoses. Eur J Surg 1997;163:929-33.
13. Allen-Mersh TG, Sprague DB, Mann CV, Turner MJ. Pelvic drainage after anterior resection of the rectum. Dis Colon Rectum 1989;32:223-6.
14. Beard JD, Nicholson ML, Sayers RD, Lloyd D, Everson NW. Intraoperative air testing of colorectal anastomoses: a prospective, randomized trial. Br J Surg 1990;77:1095-7.
15. Schmidt O, Merkel S, Hohenberger W. Anastomotic leakage after low rectal stapler anastomosis: significance of intraoperative anastomotic testing. Eur J Surg Oncol 2003;29:239-43.
16. Yalin R, Aktan AO, Yegen C, Dosluoglu H, Okboy N. Importance of testing stapled rectal anastomoses with air. Eur J Surg 1993;159:49-51.
17. Irvin TT, Goligher JC. Aetiology of disruption of intestinal anastomoses. Br J Surg 1973;60:461-4.
18. Fielding LP, Stewart-Brown S, Blesovsky L, Kearney G. Anastomotic integrity after operations for large-bowel cancer: a multicentre study. BMJ 1980;281:411-4.
19. Peeters KC, Tollenaar RA, Marijnen CA, et al. Risk factors for anastomotic failure after total mesorectal excision of rectal cancer. Br J Surg 2005;92:211-6.
20. Abulafi AM, Williams NS. Local recurrence of colorectal cancer: the problem, mechanisms, management and adjuvant therapy. Br J Surg 1994;81:7-19.
21. Fujita S, Teramoto T, Watanabe M, Kodaira S, Kitajima M. Anastomotic leakage after colorectal cancer surgery: a risk factor for recurrence and poor prognosis. Jpn J Clin Oncol 1993;23:299-302.
22. Bell SW, Walker KG, Rickard MJ, et al. Anastomotic leakage after curative anterior resection results in a higher prevalence of local recurrence. Br J Surg 2003;90:1261-6.
23. Petersen S, Freitag M, Hellmich G, Ludwig K. Anastomotic leakage: impact on local recurrence and survival in surgery of colorectal cancer. Int J Colorectal Dis 1998;13:160-3.
24. Walker KG, Bell SW, Rickard MJ, et al. Anastomotic leakage is predictive of diminished survival after potentially curative resection for colorectal cancer. Ann Surg 2004;240:255-9.
25. Graffner H, Fredlund P, Olsson SA, Oscarson J, Petersson BG. Protective colostomy in low anterior resection of the rectum using the EEA stapling instrument. A randomized study. Dis Colon Rectum 1983;26:87-90.
26. Phillips RK, Hittinger R, Blesovsky L, Fry JS, Fielding LP. Local recurrence following "curative" surgery for large bowel cancer: II. The rectum and rectosigmoid. Br J Surg 1984;71:17-20.
27. Chang SC, Lin JK, Yang SH, Jiang JK, Chen WC, Lin TC. Long-term outcome of anastomosis leakage after curative resection for mid and low rectal cancer. Hepatogastroenterology 2003;50:1898-902.
28. Branagan G, Finnis D. Prognosis after anastomotic leakage in colorectal surgery. Dis Colon Rectum 2005;48:1021-6.
29. McArdle CS, McMillan DC, Hole DJ. Impact of anastomotic leakage on long-term survival of patients undergoing curative resection for colorectal cancer. Br J Surg 2005;92:1150-4.
30. Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001;357:539-45.
31. Fermor B, Umpleby HC, Lever JV, Symes MO, Williamson RC. Proliferative and metastatic potential of exfoliated colorectal cancer cells. J Natl Cancer Inst 1986;76:347-9.
32. Law WL, Choi HK, Lee YM, Ho JW, Seto CL. Anastomotic leakage is associated with poor long-term outcome in patients after curative colorectal resection for malignancy. J Gastrointest Surg 2007;11:8-15.
33. Hotta T, Takifuji K, Arii K, et al. Clinical impact of adjuvant chemotherapy on patients with Stage III colorectal cancer. Anticancer Res 2006;26:1425-32.