Intracoronary delivery of human mesenchymal/stromal stem cells: Insights from coronary microcirculation invasive assessment in a swine model

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Fiarresga, António ^a,b   Mata, Márcia F ^c   Cavaco Gonçalves, Sandra ^d   Selas, Mafalda ^a   Simões, Irina N ^c   Oliveira, Eunice ^a   Carrapiço, Belmira ^e   Cardim, Nuno ^b   Cabral, Joaquim M S ^c   Ferreira, Rui Cruz ^a   Da Silva, Cláudia L ^c  

^a HOSPITAL DE SANTA MARTA   (Portugal)

^b NOVA MEDICAL SCHOOL   (Portugal)

^c INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^d National Institute for Agrarian and Veterinarian Research   (Portugal)

^e UNIVERSITY OF LISBON   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN ALBUMIN; PHOSPHATE BUFFERED SALINE;

ANIMAL EXPERIMENT; ARTICLE; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY PRESSURE; CORONARY FLOW RESERVE; DETERIORATION; ELECTROCARDIOGRAPHY; FEMALE; HEART MICROCIRCULATION; HUMAN; HUMAN CELL; HYPEREMIA; INDEX OF MICROCIRCULATORY RESISTANCE; INFUSION; INTRACORONARY ARTERY INFUSION; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MICROANGIOPATHY; MICROCIRCULATION; NONHUMAN; PIG; TIME; ANIMAL; CORONARY BLOOD VESSEL; CYTOLOGY; HEMODYNAMICS; PHYSIOLOGY;

ANIMALS; CORONARY CIRCULATION; CORONARY VESSELS; FEMALE; HEMODYNAMICS; HUMANS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MICROCIRCULATION; SWINE;

EID: 84949309315     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0139870     Document Type: Article

References (32)

1. Mendis S, Puska P, Norrving B editors. Global Atlas on Cardiovascular Disease Preventionand Control. World Health Organization, Geneva.; 2011.
2. Mozid AM, Arnous S, Sammut EC, Mathur A. Stem cell therapy for heart diseases. Br Med Bull. 2011; 98: 143-159.
3. Lopes JP, Fiarresga A, Silva Cunha P, Feliciano J, Cruz Ferreira R. Mesenchymal stem cell therapy in heart disease. Rev Port Cardiol. 2013; 32(1): 43-47.
4. Lennon DP, Caplan AL. Isolation of human marrow-derived mesenchymal stem cells. Exp Hematol. 2006; 34 (11): 1604-1605.
5. Bunnell BA, Flaat M, Gagliardi C, Patel B, Ripoll C. Adipose-derived stem cells: isolation, expansion and differentiation. Methods. 2008; 45(2): 115-120. doi: 10.1016/j.ymeth.2008.03.006 PMID: 18593609
6. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999; 284(5411): 143-147.
7. Patel DM, Shah J, Srivastava AS (2013) Therapeutic Potential of Mesenchymal Stem Cells in Regenerative Medicine. Stem Cells Int. 2013; 496218. doi: 10.1155/2013/496218
8. Hansson EM, Lindsay ME, Chien KR. Regeneration next: toward heart stem cell therapeutics. Cell Stem Cell. 2009; 5: 364-377.
9. Caplan AI, Dennis JE. Mesenchymal stem cells as trophic mediators. J Cell Biochem. 2006; 98: 1076-1084.
10. Eggenhofer E, Franla L, Dahlke M, Hoogduijn. The life and fate of mesenchymal stem cells. Frontiers in Immunology. 2014; 5: 148. doi: 10.3389/fimmu.2014.00148
11. Fearon WF, Balsam LB, Farouque HM, Caffarelli AD, Robbins RC, Fitzgerald PJ, et al. Novel index for invasively assessing the coronary microcirculation. Circulation. 2003; 107(25): 3129-3132.
12. Dos Santos F, Andrade PZ, Eibes G, da Silva CL. Ex vivo expansion of human mesenchymal stem cells on microcarriers. Methods Mol Biol. 2011; 698: 189-198.
13. Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006; 8(4): 315-317. PMID: 16923606
14. Pittenger MF, Martin BJ. Mesenchymal stem cells and their potential as cardiac therapeutics. Cir Res. 2004; 95: 9-20.
15. Bartunek J, Behfar A, Vanderheyden M, Wijns W, Terzic A. Mesenchymal stem cells and cardiac repair: principles and practice. J Cardiovas Transl Res. 2008; 1: 115-119.
16. Kudo M. Implantation of bone marrow stem cells reduces the infarction and fibrosis in ischemic mouse heart. J Mol Cell Cardiol. 2003; 35: 1113-1119.
17. Dai W, Hale SL, Martin BJ, Kuang JQ, Dow JS, Wold E, et al. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects. Circulation. 2005; 112: 214-223. PMID: 15998673
18. Kraitchman DL, Heldman AW, Atalar E, Amado LC, Martin BJ, Pittenger MF, et al. In vivo magnetic resonance imaging of mesenchymal stem cells in myocardial infarction. Circulation. 2003; 107: 2290-2293.
19. Amado LC, Saliaris AP, Schuleri KH, St John M, Xie JS, Cattaneo S, et al. Cardiac repair with allogeneic mesenchymal stem cells after myocardial infarction. Proc Natl Acad Sci USA. 2005; 102: 11474-11479.
20. Hare JM, Traverse JH, Henry TD, Nabil Dib, RK Strumpf, SP Schulman, et al. A randomized, doubleblind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction. J Am Coll Cardiol. 2009; 54: 2277-2286.
21. Bartunek J, Behfar A, Dolatabadi D, Vanderheyden M, Ostojic M, Dens J, et al. Cardiopoietic stem cell therapy in heart failure: the C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics. J Am Coll Cardiol. 2013; 11; 61(23): 2329-2338.
22. Freyman T, Polin G, Osman H, Crary J, Lu MM, Cheng L, et al. A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. Eur Heart J. 2006; 27: 1114-1122.
23. Perin EC, Silva GV, Assad JAR, Vela D, Buja LM, Sousa ALS, et al. Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction. J Mol Cell Cardiol. 2008; 44: 486-495.
24. Grieve SM, Bhindi R, Seow J, Doyle A, Turner AJ, Tomka J, et al. Microvascular obstruction by intracoronary delivery of mesenchymal stem cells and quantification of resulting myocardial infarction by cardiac magnetic resonance. Cir Heart Fail. 2010; 3(3): e5-6.
25. Toma C, Wagner WR, Bowry S, Schwartz A, Villanueva F. Fate of culture-expanded mesenchymal stem cells in the microvasculature: in vivo observations of cell kinetics. Circ Res. 2009; 104: 398-402.
26. Vulliet PR, Greeley M, Halloran SM, MacDonald KA, Kittleson MD. Intra-coronary arterial injection of mesenchymal stromal cells and microinfarction in dogs. Lancet. 2004; 363: 783-784.
27. Wang D, Jin Y, Ding C, Zhang F, Chen M, Yang B, et al. Intracoronary delivery of mesenchymal stem cells reduces proarrhythmogenic risks in swine with myocardial infarction. Ir J Med Sci. 2011; 180: 379-385.
28. Houtgraaf JH, De Jong R, Kazemi K, Groot D, Van Der Spoel TG, Arslan F, et al. Intracoronary Infusion of Allogeneic Mesenchymal Precursor Cells Directly Following Experimental Acute Myocardial Infarction Reduces Infarct Size, Abrogates Adverse Remodeling and Improves Cardiac Function. Cir Res. 2013; 113(2): 153-166.
29. Llano R, Epstein S, Zhou R, Zhang H, Hamamdzic D, Keane MG, et al. Intracoronary delivery of mesenchymal stem cells at high flow rates after myocardial infarction improves distal coronary blood flow and decreases mortality in pigs. Catheter Cardiovasc Interv. 2009; 73: 251-257.
30. Hong SJ, Hou D, Brinton TJ, Johnstone B, Feng D, Rogers P, et al. Intracoronary and retrograde coronary venous myocardial delivery of adipose-derived stem cells in swine infarction lead to transient myocardial trapping with predominant pulmonary redistribution. Catheter Cardiovasc Interv. 2012; 1; 83 (1): E17-25.
31. Strauer BE, Brehm M, Zeus T, Kostering M, Hernandez A, Sorg RV, et al. Repair of Infarcted Myocardium by Autologous Intracoronary Mononuclear Bone Marrow Cell Transplantation in Humans. Circulation. 2002; 106: 1913-1918.
32. Fiarresga A, Selas M, Oliveira E, Cavaco-Gonçalves S, Cacela D, Carrapiço B, et al. Invasive assessment of the coronary microcirculation using the index of microcirculatory resistance: Description and validation of an animal model. Rev Port Cardiol. 2014; 33: 207-212.