Intracoronary infusion of allogeneic mesenchymal precursor cells directly after experimental acute myocardial infarction reduces infarct size, abrogates adverse remodeling, and improves cardiac function

Circulation Research

Volumn 113, Issue 2, 2013, Pages 153-166

  Houtgraaf, Jaco H ^a   De Jong, Renate ^a   Kazemi, Kushan ^a   De Groot, Daphne ^b   Van Der Spoel, Tycho I G ^a,b   Arslan, Fatih ^b   Hoefer, Imo ^b   Pasterkamp, Gerard ^b   Itescu, Silviu ^c   Zijlstra, Felix ^a   Geleijnse, Marcel L ^a   Serruys, Patrick W ^a   Duckers, Henricus J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c Mesoblast Limited   (Australia)

Author keywords

cell transplantation; mesenchymal progenitor cell; mesenchymal stem cell; myocardial infarction; percutaneous coronary intervention; tissue therapy

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; TROPONIN I;

ACUTE HEART INFARCTION; ADVERSE OUTCOME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BALLOON OCCLUSION; BLOOD CLOT LYSIS; CAPILLARY DENSITY; CARDIOVASCULAR CATHETER; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY HEMODYNAMICS; DOSE RESPONSE; ECHOCARDIOGRAPHY; EXTRACELLULAR MATRIX; FOLLOW UP; HEART FUNCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE CELL; HEART SOUND RECORDER; HEART VENTRICLE REMODELING; INFUSION PUMP; INFUSION RATE; INTRACORONARY INFUSION; MAXIMUM TOLERATED DOSE; MESENCHYMAL STEM CELL; NICK END LABELING; NONHUMAN; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; SHEEP; THERAPY EFFECT;

CELL TRANSPLANTATION; MESENCHYMAL PROGENITOR CELL; MESENCHYMAL STEM CELL; PERCUTANEOUS CORONARY INTERVENTION TISSUE THERAPY;

ANIMALS; CORONARY VESSELS; FOLLOW-UP STUDIES; INFUSIONS, INTRA-ARTERIAL; MESENCHYMAL STEM CELL TRANSPLANTATION; MYOCARDIAL INFARCTION; RANDOM ALLOCATION; SHEEP; TRANSPLANTATION, HOMOLOGOUS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84880573296     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.300730     Document Type: Article

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