Glomerulonephritis Induced by Heterologous Anti-GBM Globulin as a Planted Foreign Antigen

Current Protocols in Immunology

Volumn 2014, Issue , 2014, Pages 15.26.1-15.26.20

  Odobasic, Dragana ^a   Ghali, Joanna R ^a   O'Sullivan, Kim M ^a   Holdsworth, Stephen R ^a,b   Kitching, A Richard ^a,b  

^a MONASH UNIVERSITY   (Australia)

^b SOUTHERN HEALTH   (Australia)

Author keywords

Cell mediated immunity; Glomerulonephritis; Planted antigen; T lymphocytes

Indexed keywords

COMPLEMENT COMPONENT C3; GLOBULIN; GLOMERULUS BASEMENT MEMBRANE ANTIBODY; IMMUNOGLOBULIN G; SHEEP GLOBULIN; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN FUNCTION; ANTIGEN SPECIFICITY; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE COURSE; GLOMERULONEPHRITIS; GLOMERULUS BASEMENT MEMBRANE; IMMUNOFLUORESCENCE TEST; IMMUNOGLOBULIN DEPOSITION; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; HUMAN; IMMUNOLOGY; PATHOLOGY; SHEEP;

ANIMALS; DISEASE MODELS, ANIMAL; GLOBULINS; GLOMERULAR BASEMENT MEMBRANE; GLOMERULONEPHRITIS; HUMANS; MICE; SHEEP;

EID: 84949256487     PISSN: 19343671     EISSN: 1934368X     Source Type: Journal    
DOI: 10.1002/0471142735.im1526s106     Document Type: Article

References (34)

1. Aitman, T.J., Dong, R., Vyse, T.J., Norsworthy, P.J., Johnson, M.D., Smith, J., Mangion, J., Roberton-Lowe, C., Marshall, A.J., Petretto, E., Hodges, M.D., Bhangal, G., Patel, S.G., Sheehan-Rooney, K., Duda, M., Cook, P.R., Evans, D.J., Domin, J., Flint, J., Boyle, J.J., Pusey, C.D., and Cook, H.T. 2006. Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature 439:851-855.
2. Boyce, N.W. and Holdsworth, S.R. 1989. Macrophage-Fc-receptor affinity: Role in cellular mediation of antibody initiated glomerulonephritis. Kidney Int. 36:537-544.
3. Devi, S., Li, A., Westhorpe, C.L., Lo, C.Y., Abeynaike, L.D., Snelgrove, S.L., Hall, P., Ooi, J.D., Sobey, C.G., Kitching, A.R., and Hickey, M.J. 2013. Multiphoton imaging reveals a newleukocyte recruitment paradigm in the glomerulus. Nat. Med. 19:107-112.
4. Dunn, S.R., Qi, Z., Bottinger, E.P., Breyer, M.D., and Sharma, K. 2004. Utility of endogenous creatinine clearance as a measure of renal function in mice. Kidney Int. 65:1959-1967.
5. Erlich, J.H., Apostolopoulos, J., Wun, T.C., Kretzmer, K.K., Holdsworth, S.R., and Tipping, P.G. 1996. Renal expression of tissue factor pathway inhibitor and evidence for a role in crescentic glomerulonephritis in rabbits. J. Clin. Invest. 98:325-335.
6. Fu, Y., Du, Y., and Mohan, C. 2007. Experimental anti-GBM disease as a tool for studying spontaneous lupus nephritis. Clin. Immunol. 124:109-118.
7. Hochheiser, K., Engel, D.R., Hammerich, L., Heymann, F., Knolle, P.A., Panzer, U., and Kurts, C. 2011. Kidney dendritic cells become pathogenic during crescentic glomerulonephritis with proteinuria. J. Am. Soc. Nephrol. 22:306-316.
8. Holdsworth, S.R., Kitching, A.R., and Tipping, P.G. 1999. Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis. Kidney Int. 55:1198-1216.
9. Huang, X.R., Holdsworth, S.R., and Tipping, P.G. 1994. Evidence for delayed type hypersensitivity mechanisms in glomerular crescent formation. Kidney Int. 46:69-78.
10. Huang, X.R., Holdsworth, S.R., and Tipping, P.G. 1997a. Th2 responses induce humorally mediated injury in experimental anti-glomerular basement membrane glomerulonephritis. J. Am. Soc. Nephrol. 8:1101-1108.
11. Huang, X.R., Tipping, P.G., Shuo, L., and Holdsworth, S.R. 1997b. Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice. Kidney Int. 51:94-103.
12. Huang, X.R., Kitching, A.R., Tipping, P.G., and Holdsworth, S.R. 2000. Interleukin-10 inhibits macrophage-induced glomerular injury. J. Am. Soc. Nephrol. 11:262-269.
13. Karkar, A.M. and Rees, A.J. 1997. Influence of endotoxin contamination on anti-GBM antibody induced glomerular injury in rats. Kidney Int. 52:1579-1583.
14. Kitching, A.R., Tipping, P.G., and Holdsworth, S.R. 1999. IL-12 directs severe renal injury, crescent formation and Th1 responses in murine glomerulonephritis. Eur. J. Immunol. 29:1-10.
15. Kitching, A.R., Holdsworth, S.R., and Tipping, P.G. 2000a. Crescentic glomerulonephritis-a manifestation of a nephritogenic Th1 response? Histol. Histopathol. 15:993-1003.
16. Kitching, A.R., Tipping, P.G., Timoshanko, J.R., and Holdsworth, S.R. 2000b. Endogenous interleukin-10 regulates Th1 responses that induce crescentic glomerulonephritis. Kidney Int. 57:518-525.
17. Kitching, A.R., Huang, X.R., Turner, A.L., Tipping, P.G., Dunn, A.R., and Holdsworth, S.R. 2002. The requirement for granulocytemacrophage colony-stimulating factor and granulocyte colony-stimulating factor in leukocytemediated immune glomerular injury. J. Am. Soc. Nephrol. 13:350-358.
18. Kitching, A.R., Turner, A.L., Wilson, G.R., Semple, T., Odobasic, D., Timoshanko, J.R., O'Sullivan K.M., Tipping, P.G., Takeda, K., Akira, S., and Holdsworth, S.R. 2005. IL-12p40 and IL-18 in crescentic glomerulonephritis: IL-12p40 is the key Th1-defining cytokine chain, whereas IL- 18 promotes local inflammation and leukocyte recruitment. J. Am. Soc. Nephrol. 16:2023-2033.
19. Kuligowski, M.P., Kitching, A.R., and Hickey, M.J. 2006. Leukocyte recruitment to the inflamed glomerulus: A critical role for platelet-derived P-selectin in the absence of rolling. J. Immunol. 176:6991-6999.
20. Li, M., O'Sullivan, K.M., Jones, L.K., Lo, C., Semple, T., Kumanogoh, A., Kikutani, H., Holdsworth, S.R., and Kitching, R. 2009. Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis. Immunology 128:114-122.
21. Li, S., Holdsworth, S.R., and Tipping, P.G. 1997. Antibody independent crescentic glomerulonephritis in μ chain deficient mice. Kidney Int. 51:672-678.
22. Li, S., Holdsworth, S.R., and Tipping, P.G. 2000. MHC class I pathway is not required for the development of crescentic glomerulonephritis in mice. Clin. Exp. Immunol. 122:453-458.
23. Masaki, T., Chow, F., Nikolic-Paterson, D.J., Atkins, R.C., and Tesch, G.H. 2003. Heterogeneity of antigen expression explains controversy over glomerular macrophage accumulation in mouse glomerulonephritis. Nephrol. Dial. Transplant. 18:178-181.
24. Masugi, M. 1934. Über die experimentelle Glomerulonephritis durch das spezifische antinieren Serum. Ein Beitrag zur Pathogenese der diffusen Glomerulonephritis. Beitr. Pathol. Anat. Allg. Pathol. 92:429-429.
25. Ophascharoensuk, V., Fero, M.L., Hughes, J., Roberts, J.M., and Shankland, S.J. 1998. The cyclin-dependent kinase inhibitor p27Kip1 safeguards against inflammatory injury. Nat. Med. 4:575-580.
26. Paust, H.J., Turner, J.E., Steinmetz, O.M., Peters, A., Heymann, F., Holscher, C., Wolf, G., Kurts, C., Mittrucker, H.W., Stahl, R.A., and Panzer, U. 2009. The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis. J. Am. Soc. Nephrol. 20:969-979.
27. Quigg, R.J., He, C., Lim, A., Berthiaume, D., Alexander, J.J., Kraus, D., and Holers, V.M. 1998. Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury. J. Exp. Med. 188:1321-1331.
28. Riedel, J.H., Paust, H.J., Turner, J.E., Tittel, A.P., Krebs, C., Disteldorf, E., Wegscheid, C., Tiegs, G., Velden, J., Mittrucker, H.W., Garbi, N., Stahl, R.A., Steinmetz, O.M., Kurts, C., and Panzer, U. 2012. Immature renal dendritic cells recruit regulatory CXCR6(+) invariant natural killer T cells to attenuate crescentic GN. J. Am. Soc. Nephrol. 23:1987-2000.
29. Salant, D.J. and Cybulsky, A.V. 1988. Experimental glomerulonephritis. Meth. Enzymol. 162:421-461.
30. Summers, S.A., Phoon, R.K., Ooi, J.D., Holdsworth, S.R., and Kitching, A.R. 2011. The IL-27 receptor has biphasic effects in crescentic glomerulonephritis mediated through Th1 responses. Am. J. Pathol. 178:580-590.
31. Tarzi, R.M., Davies, K.A., Robson, M.G., Fossati- Jimack, L., Saito, T., Walport, M.J., and Cook, H.T. 2002. Nephrotoxic nephritis is mediated by Fcgamma receptors on circulating leukocytes and not intrinsic renal cells. Kidney Int. 62:2087-2096.
32. Tipping, P.G., Huang, X.R., Berndt, M.C., and Holdsworth, S.R. 1994. A role for P selectin in complement-independent neutrophilmediated glomerular injury. Kidney Int. 46:79-88.
33. Unanue, E.R. and Dixon, F.J. 1965. Experimental glomerulonephritis. VI. The autologous phase of nephrotoxic serum nephritis. J. Exp. Med. 121:715-725.
34. Unanue, E.R., Lee, S., Dixon, F.J., and Feldman, J.D. 1965. Experimental glomerulonephritis. VII. The absence of an autoimmune antikidney response in nephrotoxic serum nephritis. J. Exp. Med. 122:565-578.