-
1
-
-
77953469917
-
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
-
10.1038/nature09230, 20535201
-
Petronis A. Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature 2010, 465(7299):721-727. 10.1038/nature09230, 20535201.
-
(2010)
Nature
, vol.465
, Issue.7299
, pp. 721-727
-
-
Petronis, A.1
-
2
-
-
0035839126
-
Epigenetic reprogramming in mammalian development
-
10.1126/science.1063443, 11498579
-
Reik W, Dean W, Walter J. Epigenetic reprogramming in mammalian development. Science 2001, 293(5532):1089-1093. 10.1126/science.1063443, 11498579.
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1089-1093
-
-
Reik, W.1
Dean, W.2
Walter, J.3
-
3
-
-
0347123629
-
Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases
-
10.1016/j.nut.2003.09.011, 14698016
-
Waterland RA, Jirtle RL. Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases. Nutrition 2004, 20(1):63-68. 10.1016/j.nut.2003.09.011, 14698016.
-
(2004)
Nutrition
, vol.20
, Issue.1
, pp. 63-68
-
-
Waterland, R.A.1
Jirtle, R.L.2
-
4
-
-
0026005763
-
Estradiol down regulates the binding activity of an avian vitellogenin gene repressor (MDBP-2) and triggers a gradual demethylation of the mCpG pair of its DNA binding site
-
10.1093/nar/19.20.5771, 328989, 1945854
-
Jost JP, Saluz HP, Pawlak A. Estradiol down regulates the binding activity of an avian vitellogenin gene repressor (MDBP-2) and triggers a gradual demethylation of the mCpG pair of its DNA binding site. Nucleic Acids Res 1991, 19(20):5771-5775. 10.1093/nar/19.20.5771, 328989, 1945854.
-
(1991)
Nucleic Acids Res
, vol.19
, Issue.20
, pp. 5771-5775
-
-
Jost, J.P.1
Saluz, H.P.2
Pawlak, A.3
-
5
-
-
0028966928
-
Sexually dimorphic DNA demethylation in the promoter of the Slp (sex-limited protein) gene in mouse liver
-
10.1073/pnas.92.5.1302, 42507, 7877972
-
Yokomori N, Moore R, Negishi M. Sexually dimorphic DNA demethylation in the promoter of the Slp (sex-limited protein) gene in mouse liver. Proc Natl Acad Sci USA 1995, 92(5):1302-1306. 10.1073/pnas.92.5.1302, 42507, 7877972.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.5
, pp. 1302-1306
-
-
Yokomori, N.1
Moore, R.2
Negishi, M.3
-
6
-
-
0037354521
-
Epigenetics and the environment
-
10.1111/j.1749-6632.2003.tb05970.x, 12724220
-
Sutherland JE, Costa M. Epigenetics and the environment. Ann NY Acad Sci 2003, 983:151-160. 10.1111/j.1749-6632.2003.tb05970.x, 12724220.
-
(2003)
Ann NY Acad Sci
, vol.983
, pp. 151-160
-
-
Sutherland, J.E.1
Costa, M.2
-
7
-
-
0027458127
-
Are somatic cells inherently deficient in methylation metabolism? A proposed mechanism for DNA methylation loss, senescence and aging
-
Cooney CA. Are somatic cells inherently deficient in methylation metabolism? A proposed mechanism for DNA methylation loss, senescence and aging. Growth Dev Aging 1993, 57(4):261-273.
-
(1993)
Growth Dev Aging
, vol.57
, Issue.4
, pp. 261-273
-
-
Cooney, C.A.1
-
8
-
-
0033988813
-
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
-
10.1038/71750, 10615135
-
Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T. DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat Genet 2000, 24(1):88-91. 10.1038/71750, 10615135.
-
(2000)
Nat Genet
, vol.24
, Issue.1
, pp. 88-91
-
-
Fuks, F.1
Burgers, W.A.2
Brehm, A.3
Hughes-Davies, L.4
Kouzarides, T.5
-
9
-
-
0038576158
-
The power and the promise of DNA methylation markers
-
Laird PW. The power and the promise of DNA methylation markers. Nat Rev Cancer 2003, 3:253-266.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 253-266
-
-
Laird, P.W.1
-
10
-
-
42649089780
-
The methylome: approaches for global DNA methylation profiling
-
10.1016/j.tig.2008.01.006, 18325624
-
Beck S, Rakyan VK. The methylome: approaches for global DNA methylation profiling. Trends Genet 2008, 24(5):231-237. 10.1016/j.tig.2008.01.006, 18325624.
-
(2008)
Trends Genet
, vol.24
, Issue.5
, pp. 231-237
-
-
Beck, S.1
Rakyan, V.K.2
-
11
-
-
77249137168
-
Principles and challenges of genomewide DNA methylation analysis
-
Laird PW. Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet 2010, 11(3):191-203.
-
(2010)
Nat Rev Genet
, vol.11
, Issue.3
, pp. 191-203
-
-
Laird, P.W.1
-
12
-
-
79960556965
-
Epigenome-wide association studies for common human diseases
-
10.1038/nrg3000, 3508712, 21747404
-
Rakyan VK, Down TA, Balding DJ, Beck S. Epigenome-wide association studies for common human diseases. Nat Rev Genet 2011, 12(8):529-541. 10.1038/nrg3000, 3508712, 21747404.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.8
, pp. 529-541
-
-
Rakyan, V.K.1
Down, T.A.2
Balding, D.J.3
Beck, S.4
-
13
-
-
61449426211
-
Methylated DNA immunoprecipitation (MeDIP)
-
Mohn F, Weber M, Schubeler D, Roloff TC. Methylated DNA immunoprecipitation (MeDIP). Meth Mol Biol 2009, 507:55-64.
-
(2009)
Meth Mol Biol
, vol.507
, pp. 55-64
-
-
Mohn, F.1
Weber, M.2
Schubeler, D.3
Roloff, T.C.4
-
14
-
-
77449127799
-
MBD-isolated genome sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genome
-
10.1093/nar/gkp992, 2811030, 19906696
-
Serre D, Lee BH, Ting AH. MBD-isolated genome sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genome. Nucleic Acids Res 2010, 38(2):391-399. 10.1093/nar/gkp992, 2811030, 19906696.
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.2
, pp. 391-399
-
-
Serre, D.1
Lee, B.H.2
Ting, A.H.3
-
15
-
-
84856306090
-
Genome-wide DNA methylation profiling using Infinium(R) assay
-
10.2217/epi.09.14, 22122642
-
Bibikova M, Le J, Barnes B, Saedinia-Melnyk S, Zhou L, Shen R, Gunderson KL. Genome-wide DNA methylation profiling using Infinium(R) assay. Epigenomics 2009, 1(1):177-200. 10.2217/epi.09.14, 22122642.
-
(2009)
Epigenomics
, vol.1
, Issue.1
, pp. 177-200
-
-
Bibikova, M.1
Le, J.2
Barnes, B.3
Saedinia-Melnyk, S.4
Zhou, L.5
Shen, R.6
Gunderson, K.L.7
-
16
-
-
84865213776
-
Methylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines
-
10.1038/ejhg.2012.33, 22378283
-
Aberg K, Khachane AN, Rudolf G, Nerella S, Fugman DA, Tischfield JA, van den Oord EJ. Methylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines. Eur J Hum Genet 2012, 20(9):953-955. 10.1038/ejhg.2012.33, 22378283.
-
(2012)
Eur J Hum Genet
, vol.20
, Issue.9
, pp. 953-955
-
-
Aberg, K.1
Khachane, A.N.2
Rudolf, G.3
Nerella, S.4
Fugman, D.A.5
Tischfield, J.A.6
van den Oord, E.J.7
-
17
-
-
84874952864
-
Enrichment-based DNA methylation analysis using next-generation sequencing: sample exclusion, estimating changes in global methylation, and the contribution of replicate lanes
-
Trimarchi MP, Murphy M, Frankhouser D, Rodriguez BA, Curfman J, Marcucci G, Yan P, Bundschuh R. Enrichment-based DNA methylation analysis using next-generation sequencing: sample exclusion, estimating changes in global methylation, and the contribution of replicate lanes. BMC Genom 2012, 13(Suppl 8):S6.
-
(2012)
BMC Genom
, vol.13
, Issue.SUPPL. 8
-
-
Trimarchi, M.P.1
Murphy, M.2
Frankhouser, D.3
Rodriguez, B.A.4
Curfman, J.5
Marcucci, G.6
Yan, P.7
Bundschuh, R.8
-
18
-
-
78649291183
-
Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage
-
10.1101/gr.110114.110, 2945193, 20802089
-
Chavez L, Jozefczuk J, Grimm C, Dietrich J, Timmermann B, Lehrach H, Herwig R, Adjaye J. Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage. Genome Res 2010, 20(10):1441-1450. 10.1101/gr.110114.110, 2945193, 20802089.
-
(2010)
Genome Res
, vol.20
, Issue.10
, pp. 1441-1450
-
-
Chavez, L.1
Jozefczuk, J.2
Grimm, C.3
Dietrich, J.4
Timmermann, B.5
Lehrach, H.6
Herwig, R.7
Adjaye, J.8
-
19
-
-
79960115813
-
High resolution detection and analysis of CpG dinucleotides methylation using MBD-Seq technology
-
10.1371/journal.pone.0022226, 3136941, 21779396
-
Lan X, Adams C, Landers M, Dudas M, Krissinger D, Marnellos G, Bonneville R, Xu M, Wang J, Huang TH. High resolution detection and analysis of CpG dinucleotides methylation using MBD-Seq technology. PLoS One 2011, 6(7):e22226. 10.1371/journal.pone.0022226, 3136941, 21779396.
-
(2011)
PLoS One
, vol.6
, Issue.7
-
-
Lan, X.1
Adams, C.2
Landers, M.3
Dudas, M.4
Krissinger, D.5
Marnellos, G.6
Bonneville, R.7
Xu, M.8
Wang, J.9
Huang, T.H.10
-
20
-
-
46949098742
-
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis
-
10.1038/nbt1414, 2644410, 18612301
-
Down TA, Rakyan VK, Turner DJ, Flicek P, Li H, Kulesha E, Graf S, Johnson N, Herrero J, Tomazou EM. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Nat Biotechnol 2008, 26(7):779-785. 10.1038/nbt1414, 2644410, 18612301.
-
(2008)
Nat Biotechnol
, vol.26
, Issue.7
, pp. 779-785
-
-
Down, T.A.1
Rakyan, V.K.2
Turner, D.J.3
Flicek, P.4
Li, H.5
Kulesha, E.6
Graf, S.7
Johnson, N.8
Herrero, J.9
Tomazou, E.M.10
-
21
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
10.1038/ng1847, 16862161
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006, 38(8):904-909. 10.1038/ng1847, 16862161.
-
(2006)
Nat Genet
, vol.38
, Issue.8
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
22
-
-
33846006923
-
Population structure and eigenanalysis
-
10.1371/journal.pgen.0020190, 1713260, 17194218
-
Patterson N, Price AL, Reich D. Population structure and eigenanalysis. PLoS Genet 2006, 2(12):e190. 10.1371/journal.pgen.0020190, 1713260, 17194218.
-
(2006)
PLoS Genet
, vol.2
, Issue.12
-
-
Patterson, N.1
Price, A.L.2
Reich, D.3
-
23
-
-
45549096818
-
Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping
-
10.1093/nar/gkn122, 2425484, 18413340
-
Bock C, Walter J, Paulsen M, Lengauer T. Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping. Nucleic Acids Res 2008, 36(10):e55. 10.1093/nar/gkn122, 2425484, 18413340.
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.10
-
-
Bock, C.1
Walter, J.2
Paulsen, M.3
Lengauer, T.4
-
25
-
-
0000071395
-
Some distance properties of latent root and vector methods used in multivariate analysis
-
Gower JC. Some distance properties of latent root and vector methods used in multivariate analysis. Biometrika 1966, 53:325-338.
-
(1966)
Biometrika
, vol.53
, pp. 325-338
-
-
Gower, J.C.1
-
27
-
-
0037864375
-
-
Godalming, United Kingdom: Network Theory Ltd, 3
-
Galassi M, Davies J, Theiler J, Gough B, Jungman G, Alken P, Booth M, Rossi F. GNU Scientific Library Reference Manual 2009, Godalming, United Kingdom: Network Theory Ltd, 3.
-
(2009)
GNU Scientific Library Reference Manual
-
-
Galassi, M.1
Davies, J.2
Theiler, J.3
Gough, B.4
Jungman, G.5
Alken, P.6
Booth, M.7
Rossi, F.8
-
28
-
-
0032714352
-
Genomic control for association studies
-
10.1111/j.0006-341X.1999.00997.x, 11315092
-
Devlin B, Roeder K. Genomic control for association studies. Biometrics 1999, 55:997-1004. 10.1111/j.0006-341X.1999.00997.x, 11315092.
-
(1999)
Biometrics
, vol.55
, pp. 997-1004
-
-
Devlin, B.1
Roeder, K.2
-
29
-
-
84871404318
-
MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case-control samples
-
10.2217/epi.12.59, 23244307
-
Aberg KA, McClay JL, Nerella S, Xie LY, Clark SL, Hudson AD, Bukszar J, Adkins D, Consortium SS, Hultman CM. MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case-control samples. Epigenomics 2012, 4(6):605-621. 10.2217/epi.12.59, 23244307.
-
(2012)
Epigenomics
, vol.4
, Issue.6
, pp. 605-621
-
-
Aberg, K.A.1
McClay, J.L.2
Nerella, S.3
Xie, L.Y.4
Clark, S.L.5
Hudson, A.D.6
Bukszar, J.7
Adkins, D.8
Consortium, S.S.9
Hultman, C.M.10
-
30
-
-
84875001647
-
Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared to bipolar disorder
-
In press
-
Bergen SE, O'Dushlaine CT, Ripke S, Lee PH, Ruderfer D, Akterin S, Moran JL, Chambert KD, Handsaker RE, Backlund L. Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared to bipolar disorder. Mol Psychiatr In press.
-
Mol Psychiatr
-
-
Bergen, S.E.1
O'Dushlaine, C.T.2
Ripke, S.3
Lee, P.H.4
Ruderfer, D.5
Akterin, S.6
Moran, J.L.7
Chambert, K.D.8
Handsaker, R.E.9
Backlund, L.10
-
31
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
International Schizophrenia Consortium
-
International Schizophrenia Consortium Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009, 460:748-752. International Schizophrenia Consortium.
-
(2009)
Nature
, vol.460
, pp. 748-752
-
-
-
32
-
-
80053384370
-
Genome-wide association study of schizophrenia identifies five novel loci
-
10.1038/ng.940, 3303194, 21926974, Schizophrenia Psychiatric Genome-Wide Association Study Consortium
-
Schizophrenia Psychiatric Genome-Wide Association Study Consortium Genome-wide association study of schizophrenia identifies five novel loci. Nat Genet 2011, 43:969-976. 10.1038/ng.940, 3303194, 21926974, Schizophrenia Psychiatric Genome-Wide Association Study Consortium.
-
(2011)
Nat Genet
, vol.43
, pp. 969-976
-
-
-
33
-
-
84859098571
-
The sva package for removing batch effects and other unwanted variation in high-throughput experiments
-
10.1093/bioinformatics/bts034, 22257669
-
Leek JT, Johnson WE, Parker HS, Jaffe AE, Storey JD. The sva package for removing batch effects and other unwanted variation in high-throughput experiments. Bioinformatics 2012, 28(6):882-883. 10.1093/bioinformatics/bts034, 22257669.
-
(2012)
Bioinformatics
, vol.28
, Issue.6
, pp. 882-883
-
-
Leek, J.T.1
Johnson, W.E.2
Parker, H.S.3
Jaffe, A.E.4
Storey, J.D.5
|