A highly tumor-specific light-triggerable drug carrier responds to hypoxic tumor conditions for effective tumor treatment

Biomaterials

Volumn 77, Issue , 2016, Pages 227-234

  Park, Wooram ^a   Bae, Byoung chan ^a   Na, Kun ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Drug delivery; Light triggered; Photosensitizer; Tumor hypoxia; Tumor treatment

Indexed keywords

CYTOTOXICITY; DISEASES; DRUG DELIVERY; PHOTOSENSITIZERS;

ANTI-TUMOR ACTIVITIES; CHONDROITIN SULFATES; COLON CANCER CELLS; NORMOXIC CONDITIONS; REACTIVE OXYGEN SPECIES; THERAPEUTIC EFFICACY; TUMOR HYPOXIA; TUMOR TREATMENT;

TUMORS;

CHONDROITIN SULFATE; DOXORUBICIN; DRUG CARRIER; PHEOPHORBIDE A; PHOTOSENSITIZING AGENT; REACTIVE OXYGEN METABOLITE; SINGLET OXYGEN; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; CHLOROPHYLL; GLASS FIBER; HYALURONIC ACID; NANOPARTICLE; POLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CELLULAR DISTRIBUTION; COLON CANCER; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG RELEASE; FEMALE; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; OXYGEN CONCENTRATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCANNING ELECTRON MICROSCOPY; ANALOGS AND DERIVATIVES; ANIMAL; CELL HYPOXIA; CHEMISTRY; CONFORMATION; DIODE LASER; DRUG SCREENING; ENERGY TRANSFER; HCT 116 CELL LINE; HUMAN; LIGHT; METABOLISM; NUDE MOUSE; OXIDATION REDUCTION REACTION; PHOTOCHEMOTHERAPY; PROCEDURES; RADIATION RESPONSE; RANDOMIZATION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CARBOHYDRATE CONFORMATION; CELL HYPOXIA; CHLOROPHYLL; CHONDROITIN SULFATES; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENERGY TRANSFER; HCT116 CELLS; HUMANS; HYALURONIC ACID; LASERS, SEMICONDUCTOR; LIGHT; MICE; MICE, NUDE; NANOPARTICLES; OPTICAL FIBERS; OXIDATION-REDUCTION; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; POLYSACCHARIDES; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; SINGLET OXYGEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84949205091     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.11.014     Document Type: Article

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