Brain protection against ischemic stroke using choline as a new molecular bypass treatment

Acta Pharmacologica Sinica

Volumn 36, Issue 12, 2015, Pages 1416-1425

  Jin, Xin ^a   Wang, Ru Huan ^b   Wang, Hui ^c   Long, Chao Liang ^a   Wang, Hai ^a,b  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b Thadweik Academy of Medicine   (China)

^c Beijing 307 Hospital   (China)

Author keywords

angiogenesis; brain microvascular endothelial cells; choline; HIF 1 ; ischemic stroke; methyllycaconitine; neovascularization; pMCAO rats; VEGF; 7 nicotinic acetylcholine receptor

Indexed keywords

BUNGAROTOXIN RECEPTOR; CHOLINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; METHYLLYCACONITINE; NIMODIPINE; SMALL INTERFERING RNA; VASCULOTROPIN; ANGIOGENIC FACTOR; NOOTROPIC AGENT;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CAPILLARY ENDOTHELIAL CELL; BRAIN FUNCTION; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; CAPILLARY DENSITY; CELL CULTURE; CELL LOSS; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG EFFICACY; GENETIC TRANSFECTION; HYPOXIA; IN VITRO STUDY; MALE; MICROVASCULATURE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; TREATMENT DURATION; ANIMAL; BRAIN; DRUG EFFECTS; INFARCTION, MIDDLE CEREBRAL ARTERY; PATHOLOGY; SPRAGUE DAWLEY RAT; VASCULARIZATION;

ANGIOGENESIS INDUCING AGENTS; ANIMALS; BRAIN; CHOLINE; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; NOOTROPIC AGENTS; RATS, SPRAGUE-DAWLEY;

EID: 84949189011     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2015.104     Document Type: Article

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