Capillary ion-exchange chromatography with nanogram sensitivity for the analysis of monoclonal antibodies

Journal of Chromatography A

Volumn 1424, Issue , 2015, Pages 77-85

  Rea, Jennifer C ^a   Freistadt, Benny S ^a   McDonald, Daniel ^a   Farnan, Dell ^a,b   Wang, Yajun Jennifer ^a  

^a GENENTECH INC   (United States)

^b GILEAD SCIENCES   (United States)

Author keywords

Antibodies; Capillary; Charge heterogeneity; Ion exchange chromatography; Monoclonal

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ION CHROMATOGRAPHY; ION EXCHANGE; IONIC STRENGTH; IONS; LIQUID CHROMATOGRAPHY; MONOCLONAL ANTIBODIES; SCREENING; SURFACE PLASMON RESONANCE;

CAPILLARY; CHARACTERIZATION METHODS; CHARGE HETEROGENEITY; ION EXCHANGE CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY SYSTEM; MONOCLONAL; MONOCLONAL ANTIBODIES (MABS); RELATIVE STANDARD DEVIATIONS;

ANTIBODIES;

MONOCLONAL ANTIBODY;

ANTIBODY DETECTION; ARTICLE; CAPILLARY CHROMATOGRAPHY; CHEMICAL PARAMETERS; CONTROLLED STUDY; ION EXCHANGE CHROMATOGRAPHY; LIQUID CHROMATOGRAPH; LIQUID CHROMATOGRAPHY; MATHEMATICAL PARAMETERS; NANOGRAM; PRIORITY JOURNAL; REGION OF INTEREST; PROCEDURES; SENSITIVITY AND SPECIFICITY;

ANTIBODIES, MONOCLONAL; CHROMATOGRAPHY, ION EXCHANGE; SENSITIVITY AND SPECIFICITY;

EID: 84949105165     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2015.11.002     Document Type: Article

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