-
1
-
-
84880770383
-
Diversifying microRNA sequence and function
-
COI: 1:CAS:528:DC%2BC3sXhtVShtrnK, PID: 23800994
-
Ameres SL, Zamore PD. Diversifying microRNA sequence and function. Nat Rev Mol Cell Biol. 2013;14:475–88.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 475-488
-
-
Ameres, S.L.1
Zamore, P.D.2
-
2
-
-
84901193349
-
MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma
-
COI: 1:CAS:528:DC%2BC3sXosFOlsrc%3D, PID: 23728341
-
Bae HJ, Noh JH, Kim JK, Eun JW, Jung KH, Kim MG, et al. MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma. Oncogene. 2014;33:2557–67.
-
(2014)
Oncogene
, vol.33
, pp. 2557-2567
-
-
Bae, H.J.1
Noh, J.H.2
Kim, J.K.3
Eun, J.W.4
Jung, K.H.5
Kim, M.G.6
-
3
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
COI: 1:CAS:528:DC%2BD1MXhs1Kiuro%3D, PID: 19167326
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136:215–33.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
4
-
-
77956249298
-
microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma
-
PID: 20739924
-
Burchard J, Zhang C, Liu AM, Poon RT, Lee NP, Wong KF, et al. microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma. Mol Syst Biol. 2010;6:402.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 402
-
-
Burchard, J.1
Zhang, C.2
Liu, A.M.3
Poon, R.T.4
Lee, N.P.5
Wong, K.F.6
-
5
-
-
34547960488
-
microRNA functions
-
COI: 1:CAS:528:DC%2BD2sXhtlartr3M, PID: 17506695
-
Bushati N, Cohen SM. microRNA functions. Annu Rev Cell Dev Biol. 2007;23:175–205.
-
(2007)
Annu Rev Cell Dev Biol
, vol.23
, pp. 175-205
-
-
Bushati, N.1
Cohen, S.M.2
-
6
-
-
34250020201
-
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
-
COI: 1:CAS:528:DC%2BD2sXnvFOgsrw%3D, PID: 17570226
-
El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. 2007;132:2557–76.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
7
-
-
33845951110
-
Cyclin D1 in non-small cell lung cancer: a key driver of malignant transformation
-
PID: 17070615
-
Gautschi O, Ratschiller D, Gugger M, Betticher DC, Heighway J. Cyclin D1 in non-small cell lung cancer: a key driver of malignant transformation. Lung Cancer. 2007;55:1–14.
-
(2007)
Lung Cancer
, vol.55
, pp. 1-14
-
-
Gautschi, O.1
Ratschiller, D.2
Gugger, M.3
Betticher, D.C.4
Heighway, J.5
-
8
-
-
84881528286
-
A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis
-
COI: 1:CAS:528:DC%2BC3sXht1Knsr%2FN, PID: 23948297
-
Kollmann K, Heller G, Schneckenleithner C, Warsch W, Scheicher R, Ott RG, et al. A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis. Cancer Cell. 2013;24:167–81.
-
(2013)
Cancer Cell
, vol.24
, pp. 167-181
-
-
Kollmann, K.1
Heller, G.2
Schneckenleithner, C.3
Warsch, W.4
Scheicher, R.5
Ott, R.G.6
-
9
-
-
50349090038
-
Astrocyte elevated gene-1 is a novel prognostic marker for breast cancer progression and overall patient survival
-
COI: 1:CAS:528:DC%2BD1cXmslygsLw%3D, PID: 18519759
-
Li J, Zhang N, Song LB, Liao WT, Jiang LL, Gong LY, et al. Astrocyte elevated gene-1 is a novel prognostic marker for breast cancer progression and overall patient survival. Clin Cancer Res. 2008;14:3319–26.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3319-3326
-
-
Li, J.1
Zhang, N.2
Song, L.B.3
Liao, W.T.4
Jiang, L.L.5
Gong, L.Y.6
-
10
-
-
84886301150
-
miR-582-5p is upregulated in patients with active tuberculosis and inhibits apoptosis of monocytes by targeting FOXO1
-
COI: 1:CAS:528:DC%2BC3sXhslWgsb3E, PID: 24205217
-
Liu YH, Jiang J, Wang XJ, Zhai F, Cheng XX. miR-582-5p is upregulated in patients with active tuberculosis and inhibits apoptosis of monocytes by targeting FOXO1. PLoS ONE. 2013;8:e78381.
-
(2013)
PLoS ONE
, vol.8
, pp. e78381
-
-
Liu, Y.H.1
Jiang, J.2
Wang, X.J.3
Zhai, F.4
Cheng, X.X.5
-
11
-
-
60749109846
-
Cell cycle, CDKs and cancer: a changing paradigm
-
COI: 1:CAS:528:DC%2BD1MXit1ans78%3D, PID: 19238148
-
Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer. 2009;9:153–66.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
12
-
-
34250788809
-
AKT/PKB signaling: navigating downstream
-
COI: 1:CAS:528:DC%2BD2sXotV2hs7g%3D, PID: 17604717
-
Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell. 2007;129:1261–74.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
13
-
-
84857654700
-
RB: mitotic implications of a tumour suppressor
-
COI: 1:CAS:528:DC%2BC38XitVWntLo%3D, PID: 22318235
-
Manning AL, Dyson NJ. RB: mitotic implications of a tumour suppressor. Nat Rev Cancer. 2012;12:220–6.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 220-226
-
-
Manning, A.L.1
Dyson, N.J.2
-
14
-
-
79960836823
-
Cyclin D as a therapeutic target in cancer
-
COI: 1:CAS:528:DC%2BC3MXos1Srsr0%3D, PID: 21734724
-
Musgrove EA, Caldon CE, Barraclough J, Stone A, Sutherland RL. Cyclin D as a therapeutic target in cancer. Nat Rev Cancer. 2011;11:558–72.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 558-572
-
-
Musgrove, E.A.1
Caldon, C.E.2
Barraclough, J.3
Stone, A.4
Sutherland, R.L.5
-
15
-
-
84892429590
-
miR-122 regulates tumorigenesis in hepatocellular carcinoma by targeting AKT3
-
COI: 1:CAS:528:DC%2BC3sXhslOjurnP, PID: 24244539
-
Nassirpour R, Mehta PP, Yin MJ. miR-122 regulates tumorigenesis in hepatocellular carcinoma by targeting AKT3. PLoS ONE. 2013;8:e79655.
-
(2013)
PLoS ONE
, vol.8
, pp. e79655
-
-
Nassirpour, R.1
Mehta, P.P.2
Yin, M.J.3
-
16
-
-
77957963491
-
Luteolin induces G1 arrest in human nasopharyngeal carcinoma cells via the Akt-GSK-3beta-Cyclin D1 pathway
-
COI: 1:CAS:528:DC%2BC3cXhtlSgt7bM, PID: 20655656
-
Ong CS, Zhou J, Ong CN, Shen HM. Luteolin induces G1 arrest in human nasopharyngeal carcinoma cells via the Akt-GSK-3beta-Cyclin D1 pathway. Cancer Lett. 2010;298:167–75.
-
(2010)
Cancer Lett
, vol.298
, pp. 167-175
-
-
Ong, C.S.1
Zhou, J.2
Ong, C.N.3
Shen, H.M.4
-
17
-
-
30144442965
-
KLF4, p21 and context-dependent opposing forces in cancer
-
COI: 1:CAS:528:DC%2BD28Xht1GgsQ%3D%3D, PID: 16372018
-
Rowland BD, Peeper DS. KLF4, p21 and context-dependent opposing forces in cancer. Nat Rev Cancer. 2006;6:11–23.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 11-23
-
-
Rowland, B.D.1
Peeper, D.S.2
-
18
-
-
84872150207
-
miR-106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma
-
COI: 1:CAS:528:DC%2BC3sXktFSjtg%3D%3D, PID: 23087084
-
Shen G, Jia HY, Tai Q, Li YH, Chen DJ. miR-106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma. Carcinogenesis. 2013;34:211–9.
-
(2013)
Carcinogenesis
, vol.34
, pp. 211-219
-
-
Shen, G.1
Jia, H.Y.2
Tai, Q.3
Li, Y.H.4
Chen, D.J.5
-
19
-
-
84865107292
-
MicroRNA-214 downregulation contributes to tumor angiogenesis by inducing secretion of the hepatoma-derived growth factor in human hepatoma
-
COI: 1:CAS:528:DC%2BC38Xht1ensr3F, PID: 22613005
-
Shih TC, Tien YJ, Wen CJ, Yeh TS, Yu MC, Huang CH, et al. MicroRNA-214 downregulation contributes to tumor angiogenesis by inducing secretion of the hepatoma-derived growth factor in human hepatoma. J Hepatol. 2012;57:584–91.
-
(2012)
J Hepatol
, vol.57
, pp. 584-591
-
-
Shih, T.C.1
Tien, Y.J.2
Wen, C.J.3
Yeh, T.S.4
Yu, M.C.5
Huang, C.H.6
-
20
-
-
59149098054
-
MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity
-
COI: 1:CAS:528:DC%2BD1MXhtFOluro%3D, PID: 19155302
-
Su H, Yang JR, Xu T, Huang J, Xu L, Yuan Y, et al. MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res. 2009;69:1135–42.
-
(2009)
Cancer Res
, vol.69
, pp. 1135-1142
-
-
Su, H.1
Yang, J.R.2
Xu, T.3
Huang, J.4
Xu, L.5
Yuan, Y.6
-
21
-
-
39049107744
-
GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy
-
COI: 1:CAS:528:DC%2BD1cXitVaqu7k%3D, PID: 18023328
-
Takahashi-Yanaga F, Sasaguri T. GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy. Cell Signal. 2008;20:581–9.
-
(2008)
Cell Signal
, vol.20
, pp. 581-589
-
-
Takahashi-Yanaga, F.1
Sasaguri, T.2
-
22
-
-
84864773072
-
MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
-
COI: 1:CAS:528:DC%2BC38Xht1SisrjK, PID: 22820290
-
Tsai WC, Hsu SD, Hsu CS, Lai TC, Chen SJ, Shen R, et al. MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. J Clin Invest. 2012;122:2884–97.
-
(2012)
J Clin Invest
, vol.122
, pp. 2884-2897
-
-
Tsai, W.C.1
Hsu, S.D.2
Hsu, C.S.3
Lai, T.C.4
Chen, S.J.5
Shen, R.6
-
23
-
-
84875216772
-
Therapeutic effects of microRNA-582-5p and -3p on the inhibition of bladder cancer progression
-
COI: 1:CAS:528:DC%2BC3sXkt1Wisg%3D%3D
-
Uchino K, Takeshita F, Takahashi RU, Kosaka N, Fujiwara K, Naruoka H, et al. Therapeutic effects of microRNA-582-5p and -3p on the inhibition of bladder cancer progression. Mol Ther J Am Soc Gene Ther. 2013;21:610–9.
-
(2013)
Mol Ther J Am Soc Gene Ther
, vol.21
, pp. 610-619
-
-
Uchino, K.1
Takeshita, F.2
Takahashi, R.U.3
Kosaka, N.4
Fujiwara, K.5
Naruoka, H.6
-
24
-
-
84898430214
-
MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer
-
COI: 1:CAS:528:DC%2BC2cXmt1Wks7k%3D, PID: 24735923
-
Valeri N, Braconi C, Gasparini P, Murgia C, Lampis A, Paulus-Hock V, et al. MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer. Cancer Cell. 2014;25:469–83.
-
(2014)
Cancer Cell
, vol.25
, pp. 469-483
-
-
Valeri, N.1
Braconi, C.2
Gasparini, P.3
Murgia, C.4
Lampis, A.5
Paulus-Hock, V.6
-
25
-
-
84857406235
-
PI3K signalling: the path to discovery and understanding
-
COI: 1:CAS:528:DC%2BC38Xis1eqt7s%3D, PID: 22358332
-
Vanhaesebroeck B, Stephens L, Hawkins P. PI3K signalling: the path to discovery and understanding. Nat Rev Mol Cell Biol. 2012;13:195–203.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 195-203
-
-
Vanhaesebroeck, B.1
Stephens, L.2
Hawkins, P.3
-
26
-
-
84880308946
-
Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo
-
COI: 1:CAS:528:DC%2BC3sXhtVaktL7I, PID: 23471882
-
Wu W, Ye H, Wan L, Han X, Wang G, Hu J, et al. Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo. Carcinogenesis. 2013;34:1636–43.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1636-1643
-
-
Wu, W.1
Ye, H.2
Wan, L.3
Han, X.4
Wang, G.5
Hu, J.6
-
27
-
-
84893749271
-
MicroRNA miR-302 inhibits the tumorigenicity of endometrial cancer cells by suppression of Cyclin D1 and CDK1
-
COI: 1:CAS:528:DC%2BC3sXhvFOgsbrJ, PID: 24333727
-
Yan GJ, Yu F, Wang B, Zhou HJ, Ge QY, Su J, et al. MicroRNA miR-302 inhibits the tumorigenicity of endometrial cancer cells by suppression of Cyclin D1 and CDK1. Cancer Lett. 2014;345:39–47.
-
(2014)
Cancer Lett
, vol.345
, pp. 39-47
-
-
Yan, G.J.1
Yu, F.2
Wang, B.3
Zhou, H.J.4
Ge, Q.Y.5
Su, J.6
-
28
-
-
77951491943
-
miR-17-5p promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway
-
COI: 1:CAS:528:DC%2BC3cXntFCqtbk%3D, PID: 20209605
-
Yang F, Yin Y, Wang F, Wang Y, Zhang L, Tang Y, et al. miR-17-5p promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway. Hepatology. 2010;51:1614–23.
-
(2010)
Hepatology
, vol.51
, pp. 1614-1623
-
-
Yang, F.1
Yin, Y.2
Wang, F.3
Wang, Y.4
Zhang, L.5
Tang, Y.6
-
29
-
-
84904563942
-
MicroRNA-224 upregulation and AKT activation synergistically predict poor prognosis in patients with hepatocellular carcinoma
-
Yu L, Zhang J, Guo X, Li Z, Zhang P. MicroRNA-224 upregulation and AKT activation synergistically predict poor prognosis in patients with hepatocellular carcinoma. Cancer Epidemiol. 2014;38:408–13.
-
(2014)
Cancer Epidemiol
, vol.38
, pp. 408-413
-
-
Yu, L.1
Zhang, J.2
Guo, X.3
Li, Z.4
Zhang, P.5
-
30
-
-
84878196007
-
The role of CDK1 in apoptin-induced apoptosis in hepatocellular carcinoma cells
-
COI: 1:CAS:528:DC%2BC3sXht1Wit7rN, PID: 23619525
-
Zhao J, Han SX, Ma JL, Ying X, Liu P, Li J, et al. The role of CDK1 in apoptin-induced apoptosis in hepatocellular carcinoma cells. Oncol Rep. 2013;30:253–9.
-
(2013)
Oncol Rep
, vol.30
, pp. 253-259
-
-
Zhao, J.1
Han, S.X.2
Ma, J.L.3
Ying, X.4
Liu, P.5
Li, J.6
-
31
-
-
84871716820
-
miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6
-
COI: 1:CAS:528:DC%2BC38Xhslyntb%2FN, PID: 23178712
-
Zhu X, Li Y, Shen H, Li H, Long L, Hui L, et al. miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6. FEBS Lett. 2013;587:73–81.
-
(2013)
FEBS Lett
, vol.587
, pp. 73-81
-
-
Zhu, X.1
Li, Y.2
Shen, H.3
Li, H.4
Long, L.5
Hui, L.6
|