-
1
-
-
0035795598
-
The multifaceted challenges of proteus syndrome
-
Biesecker, L. G. The Multifaceted Challenges of Proteus Syndrome. JAMA 285, 2240-2243 (2001).
-
(2001)
JAMA
, vol.285
, pp. 2240-2243
-
-
Biesecker, L.G.1
-
2
-
-
34547172596
-
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer
-
Carpten, J. D. et al. A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature 448, 439-444 (2007).
-
(2007)
Nature
, vol.448
, pp. 439-444
-
-
Carpten, J.D.1
-
3
-
-
84860389181
-
A mosaic activating mutation in akt1 associated with the proteus syndrome
-
Lindhurst, M. J. et al. A Mosaic Activating Mutation in AKT1 Associated with the Proteus Syndrome. New Engl. J. Med. 365, 611-619 (2011).
-
(2011)
New Engl. J. Med.
, vol.365
, pp. 611-619
-
-
Lindhurst, M.J.1
-
4
-
-
0025022621
-
Proteus Syndrome: Course of a Severe Case
-
Malamitsi-Puchner, A., Dimitriadis, D., Bartsocas, C. & Wiedemann, H. R. Proteus Syndrome: Course of a Severe Case. Am. J. Med. Genet. 35, 283-285 (1990).
-
(1990)
Am. J. Med. Genet.
, vol.35
, pp. 283-285
-
-
Malamitsi-Puchner, A.1
Dimitriadis, D.2
Bartsocas, C.3
Wiedemann, H.R.4
-
5
-
-
33751245303
-
Case report: Morphological characterization of the breast in proteus syndrome complicated by ductal carcinoma in situ
-
Iqbal, J. et al. Case Report:Morphological Characterization of the Breast in Proteus Syndrome Complicated by Ductal Carcinoma In Situ. Ann. Clin. Lab. Sci. 36, 469-474 (2006).
-
(2006)
Ann. Clin. Lab. Sci.
, vol.36
, pp. 469-474
-
-
Iqbal, J.1
-
6
-
-
4644251811
-
Reassessment of the Proteus syndrome literature: Application of diagnostic criteria to published cases
-
Turner, J. T., Cohen, M. M., Jr. & Biesecker, L. G. Reassessment of the Proteus syndrome literature: Application of diagnostic criteria to published cases. Am. J. Med. Genet. 130A, 111-122 (2004).
-
(2004)
Am. J. Med. Genet.
, vol.130 A
, pp. 111-122
-
-
Turner, J.T.1
Cohen, M.M.2
Biesecker, L.G.3
-
7
-
-
0033665231
-
Sudden death caused by pulmonary thromboembolism in Proteus syndrome
-
Slavotinek, A. M., Vacha, S. J., Peters, K. F. & Biesecker, L. G. Sudden death caused by pulmonary thromboembolism in Proteus syndrome. Clin. Genet. 58, 386-389 (2000).
-
(2000)
Clin. Genet.
, vol.58
, pp. 386-389
-
-
Slavotinek, A.M.1
Vacha, S.J.2
Peters, K.F.3
Biesecker, L.G.4
-
8
-
-
56749168073
-
Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain
-
Landgraf, K. E., Pilling, C. & Falke, J. J. Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain. Biochemistry 47, 12260-12269 (2008).
-
(2008)
Biochemistry
, vol.47
, pp. 12260-12269
-
-
Landgraf, K.E.1
Pilling, C.2
Falke, J.J.3
-
9
-
-
84869774399
-
Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers
-
Parikh, C. et al. Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers. Proc. Natl. Aca. Sci., USA 109, 19368-19373 (2012).
-
(2012)
Proc. Natl. Aca. Sci., USA
, vol.109
, pp. 19368-19373
-
-
Parikh, C.1
-
10
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning, B. D. & Cantley, L. C. AKT/PKB Signaling: Navigating Downstream. Cell 129, 1261-1274 (2007).
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
11
-
-
84949670704
-
In vitro and in vivo anti-tumor activity of ARQ 092, a potent and selective pan-AKT inhibitor
-
Yu, Y. et al. In vitro and in vivo anti-tumor activity of ARQ 092, a potent and selective pan-AKT inhibitor. Eur. J. Cancer 50, 172-173 (2014).
-
(2014)
Eur. J. Cancer
, vol.50
, pp. 172-173
-
-
Yu, Y.1
-
12
-
-
0037855834
-
Identification of a Proline-rich Akt Substrate as a 14-3-3 Binding Partner
-
Kovacina, K. S. Identification of a Proline-rich Akt Substrate as a 14-3-3 Binding Partner. J. Biol. Chem. 278, 10189-10194 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10189-10194
-
-
Kovacina, K.S.1
-
13
-
-
84856715458
-
GSK-3: Functional insights from cell biology and animal models
-
Kaidanovich-Beilin, O. & Woodgett, J. R. GSK-3: functional insights from cell biology and animal models. Front. Mol. Neurosci. 4, 1-25 (2011).
-
(2011)
Front. Mol. Neurosci.
, vol.4
, pp. 1-25
-
-
Kaidanovich-Beilin, O.1
Woodgett, J.R.2
-
14
-
-
84900034723
-
FOXO transcription factors: Their clinical significance and regulation
-
Wang, Y., Zhou, Y. & Graves, D. T. FOXO Transcription Factors: Their Clinical Significance and Regulation. BioMed Res. Int. 2014, 1-13 (2014).
-
(2014)
BioMed Res. Int.
, vol.2014
, pp. 1-13
-
-
Wang, Y.1
Zhou, Y.2
Graves, D.T.3
-
15
-
-
68149107692
-
BAD: Undertaker by night, candyman by day
-
Danial, N. N. BAD: undertaker by night, candyman by day. Oncogene 27, S53-S70 (2009).
-
(2009)
Oncogene
, vol.27
, pp. S53-S70
-
-
Danial, N.N.1
-
16
-
-
52049103675
-
Physiological roles of ribosomal protein S6: One of its kind
-
Elsevier
-
Meyuhas, O. Physiological roles of ribosomal protein S6: One of its kind. in International Review of Cell and Molecular Biology 268, 1-37 (Elsevier, 2008).
-
(2008)
International Review of Cell and Molecular Biology
, vol.268
, pp. 1-37
-
-
Meyuhas, O.1
-
17
-
-
78650239404
-
Functions and regulation of the 70 kDa ribosomal S6 kinases
-
Fenton, T. R. & Gout, I. T. Functions and regulation of the 70 kDa ribosomal S6 kinases. Int. J. Biochem. Cell Biol. 43, 47-59 (2011).
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 47-59
-
-
Fenton, T.R.1
Gout, I.T.2
-
18
-
-
0016283728
-
Platelets as a source of fibroblast growth-promoting activity
-
Kohler, N. & Lipton, A. Platelets as a source of fibroblast growth-promoting activity. Exp. Cell Res. 87, 297-301 (1974).
-
(1974)
Exp. Cell Res.
, vol.87
, pp. 297-301
-
-
Kohler, N.1
Lipton, A.2
-
19
-
-
44149090296
-
Role of platelet-derived growth factors in physiology and medicine
-
Andrae, J., Gallini, R. & Betsholtz, C. Role of platelet-derived growth factors in physiology and medicine. Gene. Dev. 22, 1276-1312 (2008).
-
(2008)
Gene. Dev.
, vol.22
, pp. 1276-1312
-
-
Andrae, J.1
Gallini, R.2
Betsholtz, C.3
-
20
-
-
0029079275
-
The Protein Kinase Encoded by the Akt Proto-Oncogene Is a Target of the PDGF-Activated Phosphatidylinositol 3-Kinase
-
5AD
-
Franke, T. F. et al. The Protein Kinase Encoded by the Akt Proto-Oncogene Is a Target of the PDGF-Activated Phosphatidylinositol 3-Kinase. Cell 81, 727-736. (5AD).
-
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
-
21
-
-
0027499070
-
The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity
-
Crouch, S. P. M., R, K., J, S. K. & Fletcher, J. The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity. J. Immunol. Methods 160, 81-88 (1993).
-
(1993)
J. Immunol. Methods
, vol.160
, pp. 81-88
-
-
Crouch, S.P.M.1
Fletcher, J.2
-
22
-
-
84948992076
-
First-in-human study with ARQ 092, a novel pan AKT-inhibitor, in subjects with advanced solid tumors or recurrent malignant lymphoma
-
Saleh, M. et al. First-in-human study with ARQ 092, a novel pan AKT-inhibitor, in subjects with advanced solid tumors or recurrent malignant lymphoma. Eur. J. Cancer 50, 104 (2014).
-
(2014)
Eur. J. Cancer
, vol.50
, pp. 104
-
-
Saleh, M.1
-
23
-
-
67349127898
-
The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents
-
Sankhala, K. et al. The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents. Target. Oncol. 4, 135-142 (2009).
-
(2009)
Target. Oncol.
, vol.4
, pp. 135-142
-
-
Sankhala, K.1
-
24
-
-
84892803361
-
AKT1 gene mutation levels are correlated with the type of dermatologic lesions in patients with proteus syndrome
-
Lindhurst, M. J. et al. AKT1 Gene Mutation Levels Are Correlated with the Type of Dermatologic Lesions in Patients with Proteus Syndrome. J. Invest. Dermatol. 134, 543-546 (2013).
-
(2013)
J. Invest. Dermatol.
, vol.134
, pp. 543-546
-
-
Lindhurst, M.J.1
-
25
-
-
84864409793
-
Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA
-
Lindhurst, M. J. et al. Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA. Nat. Genet. 44, 928-933 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 928-933
-
-
Lindhurst, M.J.1
|