메뉴 건너뛰기




Volumn 11, Issue 11, 2015, Pages

Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Induces the Oncogenic miR-17-92 Cluster and Down-Regulates TGF-β Signaling

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; FLICE INHIBITORY PROTEIN; MICRORNA; MICRORNA 17-92; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; MIRN17-92 MICRORNA, HUMAN;

EID: 84948992813     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005255     Document Type: Article
Times cited : (40)

References (59)
  • 1
    • 0028588064 scopus 로고
    • Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma [see comments]
    • Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, et al. (1994) Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma [see comments]. Science 266: 1865–1869. 7997879
    • (1994) Science , vol.266 , pp. 1865-1869
    • Chang, Y.1    Cesarman, E.2    Pessin, M.S.3    Lee, F.4    Culpepper, J.5
  • 2
    • 0029166033 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease
    • Soulier J, Grollet L, Oksenhendler E, Cacoub P, Cazals-Hatem D, et al. (1995) Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 86: 1276–1280. 7632932
    • (1995) Blood , vol.86 , pp. 1276-1280
    • Soulier, J.1    Grollet, L.2    Oksenhendler, E.3    Cacoub, P.4    Cazals-Hatem, D.5
  • 3
    • 0029069445 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas
    • Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM, (1995) Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med 332: 1186–1191. 7700311
    • (1995) N Engl J Med , vol.332 , pp. 1186-1191
    • Cesarman, E.1    Chang, Y.2    Moore, P.S.3    Said, J.W.4    Knowles, D.M.5
  • 4
    • 1842631466 scopus 로고    scopus 로고
    • KSHV vFLIP is essential for the survival of infected lymphoma cells
    • Guasparri I, Keller SA, Cesarman E, (2004) KSHV vFLIP is essential for the survival of infected lymphoma cells. J Exp Med 199: 993–1003. 15067035
    • (2004) J Exp Med , vol.199 , pp. 993-1003
    • Guasparri, I.1    Keller, S.A.2    Cesarman, E.3
  • 5
    • 0346101776 scopus 로고    scopus 로고
    • The human herpes virus 8-encoded viral FLICE-inhibitory protein induces cellular transformation via NF-kappaB activation
    • Sun Q, Zachariah S, Chaudhary PM, (2003) The human herpes virus 8-encoded viral FLICE-inhibitory protein induces cellular transformation via NF-kappaB activation. J Biol Chem 278: 52437–52445. 14563855
    • (2003) J Biol Chem , vol.278 , pp. 52437-52445
    • Sun, Q.1    Zachariah, S.2    Chaudhary, P.M.3
  • 6
    • 84931023553 scopus 로고    scopus 로고
    • Inefficient codon usage impairs mRNA accumulation: the case of the v-FLIP gene of Kaposi's sarcoma-associated herpesvirus
    • Bellare P, Dufresne A, Ganem D, (2015) Inefficient codon usage impairs mRNA accumulation: the case of the v-FLIP gene of Kaposi's sarcoma-associated herpesvirus. J Virol.
    • (2015) J Virol
    • Bellare, P.1    Dufresne, A.2    Ganem, D.3
  • 7
    • 84923839967 scopus 로고    scopus 로고
    • Systemic expression of Kaposi sarcoma herpesvirus (KSHV) Vflip in endothelial cells leads to a profound proinflammatory phenotype and myeloid lineage remodeling in vivo
    • Ballon G, Akar G, Cesarman E, (2015) Systemic expression of Kaposi sarcoma herpesvirus (KSHV) Vflip in endothelial cells leads to a profound proinflammatory phenotype and myeloid lineage remodeling in vivo. PLoS pathogens 11: e1004581. doi: 10.1371/journal.ppat.1004581 25607954
    • (2015) PLoS pathogens , vol.11 , pp. 1004581
    • Ballon, G.1    Akar, G.2    Cesarman, E.3
  • 8
    • 70449529788 scopus 로고    scopus 로고
    • FLIP-mediated autophagy regulation in cell death control
    • Lee JS, Li QL, Lee JY, Lee SH, Jeong JH, et al. (2009) FLIP-mediated autophagy regulation in cell death control. Nature cell biology 11: 1355–U1225. doi: 10.1038/ncb1980 19838173
    • (2009) Nature cell biology , vol.11 , pp. 1225-1355
    • Lee, J.S.1    Li, Q.L.2    Lee, J.Y.3    Lee, S.H.4    Jeong, J.H.5
  • 9
    • 84901325841 scopus 로고    scopus 로고
    • Viral and cellular FLICE-inhibitory proteins: a comparison of their roles in regulating intrinsic immune responses
    • Shisler JL, (2014) Viral and cellular FLICE-inhibitory proteins: a comparison of their roles in regulating intrinsic immune responses. J Virol 88: 6539–6541. doi: 10.1128/JVI.00276-14 24719415
    • (2014) J Virol , vol.88 , pp. 6539-6541
    • Shisler, J.L.1
  • 10
    • 0005086346 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Uganda Kaposi's Sarcoma Study Group
    • Chang Y, Ziegler J, Wabinga H, Katangole-Mbidde E, Boshoff C, et al. (1996) Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Uganda Kaposi's Sarcoma Study Group. Arch Intern Med 156: 202–204. 8546554
    • (1996) Arch Intern Med , vol.156 , pp. 202-204
    • Chang, Y.1    Ziegler, J.2    Wabinga, H.3    Katangole-Mbidde, E.4    Boshoff, C.5
  • 11
    • 0030697223 scopus 로고    scopus 로고
    • Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins
    • Swanton C, Mann DJ, Fleckenstein B, Neipel F, Peters G, et al. (1997) Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins. Nature 390: 184–187. 9367157
    • (1997) Nature , vol.390 , pp. 184-187
    • Swanton, C.1    Mann, D.J.2    Fleckenstein, B.3    Neipel, F.4    Peters, G.5
  • 12
    • 0036730664 scopus 로고    scopus 로고
    • The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo
    • Verschuren EW, Klefstrom J, Evan GI, Jones N, (2002) The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo. Cancer cell 2: 229–241. 12242155
    • (2002) Cancer cell , vol.2 , pp. 229-241
    • Verschuren, E.W.1    Klefstrom, J.2    Evan, G.I.3    Jones, N.4
  • 13
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281–297. 14744438
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 14
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V, (2004) The functions of animal microRNAs. Nature 431: 350–355. 15372042
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 15
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, et al. (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 101: 2999–3004. 14973191
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3    Hyslop, T.4    Noch, E.5
  • 16
    • 2342449399 scopus 로고    scopus 로고
    • Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma
    • Ota A, Tagawa H, Karnan S, Tsuzuki S, Karpas A, et al. (2004) Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res 64: 3087–3095. 15126345
    • (2004) Cancer Res , vol.64 , pp. 3087-3095
    • Ota, A.1    Tagawa, H.2    Karnan, S.3    Tsuzuki, S.4    Karpas, A.5
  • 17
    • 27644570319 scopus 로고    scopus 로고
    • A microRNA cluster as a target of genomic amplification in malignant lymphoma
    • Tagawa H, Seto M, (2005) A microRNA cluster as a target of genomic amplification in malignant lymphoma. Leukemia 19: 2013–2016. 16167061
    • (2005) Leukemia , vol.19 , pp. 2013-2016
    • Tagawa, H.1    Seto, M.2
  • 20
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods K, Thomson JM, Hammond SM, (2007) Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 282: 2130–2134. 17135268
    • (2007) J Biol Chem , vol.282 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 21
    • 78649941638 scopus 로고    scopus 로고
    • The miR-17-92 microRNA cluster regulates multiple components of the TGF-beta pathway in neuroblastoma
    • Mestdagh P, Bostrom AK, Impens F, Fredlund E, Van Peer G, et al. (2010) The miR-17-92 microRNA cluster regulates multiple components of the TGF-beta pathway in neuroblastoma. Mol Cell 40: 762–773. doi: 10.1016/j.molcel.2010.11.038 21145484
    • (2010) Mol Cell , vol.40 , pp. 762-773
    • Mestdagh, P.1    Bostrom, A.K.2    Impens, F.3    Fredlund, E.4    Van Peer, G.5
  • 22
    • 77954382780 scopus 로고    scopus 로고
    • mir-17-92, a cluster of miRNAs in the midst of the cancer network
    • Olive V, Jiang I, He L, (2010) mir-17-92, a cluster of miRNAs in the midst of the cancer network. Int J Biochem Cell Biol 42: 1348–1354. doi: 10.1016/j.biocel.2010.03.004 20227518
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1348-1354
    • Olive, V.1    Jiang, I.2    He, L.3
  • 23
    • 79952706985 scopus 로고    scopus 로고
    • Transforming growth factor-beta and the hallmarks of cancer
    • Tian M, Neil JR, Schiemann WP, (2011) Transforming growth factor-beta and the hallmarks of cancer. Cellular signalling 23: 951–962. doi: 10.1016/j.cellsig.2010.10.015 20940046
    • (2011) Cellular signalling , vol.23 , pp. 951-962
    • Tian, M.1    Neil, J.R.2    Schiemann, W.P.3
  • 25
    • 44649172694 scopus 로고    scopus 로고
    • KSHV LANA inhibits TGF-beta signaling through epigenetic silencing of the TGF-beta type II receptor
    • Di Bartolo DL, Cannon M, Liu YF, Renne R, Chadburn A, et al. (2008) KSHV LANA inhibits TGF-beta signaling through epigenetic silencing of the TGF-beta type II receptor. Blood 111: 4731–4740. doi: 10.1182/blood-2007-09-110544 18199825
    • (2008) Blood , vol.111 , pp. 4731-4740
    • Di Bartolo, D.L.1    Cannon, M.2    Liu, Y.F.3    Renne, R.4    Chadburn, A.5
  • 26
    • 33745515023 scopus 로고    scopus 로고
    • Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer
    • Bierie B, Moses HL, (2006) Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer. Nature reviews Cancer 6: 506–520. 16794634
    • (2006) Nature reviews Cancer , vol.6 , pp. 506-520
    • Bierie, B.1    Moses, H.L.2
  • 27
    • 1642332084 scopus 로고    scopus 로고
    • Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
    • Seoane J, Le HV, Shen L, Anderson SA, Massague J, (2004) Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Cell 117: 211–223. 15084259
    • (2004) Cell , vol.117 , pp. 211-223
    • Seoane, J.1    Le, H.V.2    Shen, L.3    Anderson, S.A.4    Massague, J.5
  • 28
    • 33748208668 scopus 로고    scopus 로고
    • C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells
    • Gomis RR, Alarcon C, Nadal C, Van Poznak C, Massague J, (2006) C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells. Cancer cell 10: 203–214. 16959612
    • (2006) Cancer cell , vol.10 , pp. 203-214
    • Gomis, R.R.1    Alarcon, C.2    Nadal, C.3    Van Poznak, C.4    Massague, J.5
  • 29
    • 84866150841 scopus 로고    scopus 로고
    • Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas
    • Haecker I, Gay LA, Yang Y, Hu J, Morse AM, et al. (2012) Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas. PLoS pathogens 8: e1002884. doi: 10.1371/journal.ppat.1002884 22927820
    • (2012) PLoS pathogens , vol.8 , pp. 1002884
    • Haecker, I.1    Gay, L.A.2    Yang, Y.3    Hu, J.4    Morse, A.M.5
  • 30
    • 66349116753 scopus 로고    scopus 로고
    • Pre-micro RNA signatures delineate stages of endothelial cell transformation in Kaposi sarcoma
    • O'Hara AJ, Chugh P, Wang L, Netto EM, Luz E, et al. (2009) Pre-micro RNA signatures delineate stages of endothelial cell transformation in Kaposi sarcoma. PLoS pathogens 5: e1000389. doi: 10.1371/journal.ppat.1000389 19381257
    • (2009) PLoS pathogens , vol.5 , pp. 1000389
    • O'Hara, A.J.1    Chugh, P.2    Wang, L.3    Netto, E.M.4    Luz, E.5
  • 31
    • 37249092180 scopus 로고    scopus 로고
    • A viral microRNA functions as an orthologue of cellular miR-155
    • Gottwein E, Mukherjee N, Sachse C, Frenzel C, Majoros WH, et al. (2007) A viral microRNA functions as an orthologue of cellular miR-155. Nature 450: 1096–1099. 18075594
    • (2007) Nature , vol.450 , pp. 1096-1099
    • Gottwein, E.1    Mukherjee, N.2    Sachse, C.3    Frenzel, C.4    Majoros, W.H.5
  • 32
    • 36349035211 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus encodes an ortholog of miR-155
    • Skalsky RL, Samols MA, Plaisance KB, Boss IW, Riva A, et al. (2007) Kaposi's sarcoma-associated herpesvirus encodes an ortholog of miR-155. J Virol 81: 12836–12845. 17881434
    • (2007) J Virol , vol.81 , pp. 12836-12845
    • Skalsky, R.L.1    Samols, M.A.2    Plaisance, K.B.3    Boss, I.W.4    Riva, A.5
  • 33
    • 0036827642 scopus 로고    scopus 로고
    • The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cells
    • Hu J, Garber AC, Renne R, (2002) The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cells. J Virol 76: 11677–11687. 12388727
    • (2002) J Virol , vol.76 , pp. 11677-11687
    • Hu, J.1    Garber, A.C.2    Renne, R.3
  • 34
    • 84866184336 scopus 로고    scopus 로고
    • Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone
    • Brulois KF, Chang H, Lee AS, Ensser A, Wong LY, et al. (2012) Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone. J Virol 86: 9708–9720. doi: 10.1128/JVI.01019-12 22740391
    • (2012) J Virol , vol.86 , pp. 9708-9720
    • Brulois, K.F.1    Chang, H.2    Lee, A.S.3    Ensser, A.4    Wong, L.Y.5
  • 35
    • 84873998737 scopus 로고    scopus 로고
    • Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line
    • Sturzl M, Gaus D, Dirks WG, Ganem D, Jochmann R, (2013) Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line. International journal of cancer Journal international du cancer 132: 1954–1958. doi: 10.1002/ijc.27849 22987579
    • (2013) International journal of cancer Journal international du cancer , vol.132 , pp. 1954-1958
    • Sturzl, M.1    Gaus, D.2    Dirks, W.G.3    Ganem, D.4    Jochmann, R.5
  • 36
    • 33646440294 scopus 로고    scopus 로고
    • Long-term-infected telomerase-immortalized endothelial cells: a model for Kaposi's sarcoma-associated herpesvirus latency in vitro and in vivo
    • An FQ, Folarin HM, Compitello N, Roth J, Gerson SL, et al. (2006) Long-term-infected telomerase-immortalized endothelial cells: a model for Kaposi's sarcoma-associated herpesvirus latency in vitro and in vivo. J Virol 80: 4833–4846. 16641275
    • (2006) J Virol , vol.80 , pp. 4833-4846
    • An, F.Q.1    Folarin, H.M.2    Compitello, N.3    Roth, J.4    Gerson, S.L.5
  • 37
    • 79955754014 scopus 로고    scopus 로고
    • Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: Maintenance of tight latency with efficient reactivation upon induction
    • Myoung J, Ganem D, (2011) Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: Maintenance of tight latency with efficient reactivation upon induction. J Virol Methods 174: 12–21. doi: 10.1016/j.jviromet.2011.03.012 21419799
    • (2011) J Virol Methods , vol.174 , pp. 12-21
    • Myoung, J.1    Ganem, D.2
  • 38
    • 49949116902 scopus 로고    scopus 로고
    • The impact of microRNAs on protein output
    • Baek D, Villen J, Shin C, Camargo FD, Gygi SP, et al. (2008) The impact of microRNAs on protein output. Nature 455: 64–71. doi: 10.1038/nature07242 18668037
    • (2008) Nature , vol.455 , pp. 64-71
    • Baek, D.1    Villen, J.2    Shin, C.3    Camargo, F.D.4    Gygi, S.P.5
  • 39
    • 49949117302 scopus 로고    scopus 로고
    • Widespread changes in protein synthesis induced by microRNAs
    • Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, et al. (2008) Widespread changes in protein synthesis induced by microRNAs. Nature 455: 58–63. doi: 10.1038/nature07228 18668040
    • (2008) Nature , vol.455 , pp. 58-63
    • Selbach, M.1    Schwanhausser, B.2    Thierfelder, N.3    Fang, Z.4    Khanin, R.5
  • 40
    • 84869074612 scopus 로고    scopus 로고
    • A Kaposi's sarcoma-associated herpesvirus microRNA and its variants target the transforming growth factor beta pathway to promote cell survival
    • Lei X, Zhu Y, Jones T, Bai Z, Huang Y, et al. (2012) A Kaposi's sarcoma-associated herpesvirus microRNA and its variants target the transforming growth factor beta pathway to promote cell survival. J Virol 86: 11698–11711. doi: 10.1128/JVI.06855-11 22915806
    • (2012) J Virol , vol.86 , pp. 11698-11711
    • Lei, X.1    Zhu, Y.2    Jones, T.3    Bai, Z.4    Huang, Y.5
  • 41
    • 84863128531 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-encoded microRNA miR-K12-11 attenuates transforming growth factor beta signaling through suppression of SMAD5
    • Liu Y, Sun R, Lin X, Liang D, Deng Q, et al. (2012) Kaposi's sarcoma-associated herpesvirus-encoded microRNA miR-K12-11 attenuates transforming growth factor beta signaling through suppression of SMAD5. J Virol 86: 1372–1381. doi: 10.1128/JVI.06245-11 22013049
    • (2012) J Virol , vol.86 , pp. 1372-1381
    • Liu, Y.1    Sun, R.2    Lin, X.3    Liang, D.4    Deng, Q.5
  • 42
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, et al. (2005) A microRNA polycistron as a potential human oncogene. Nature 435: 828–833. 15944707
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3    Hernando-Monge, E.4    Mu, D.5
  • 43
    • 84880255629 scopus 로고    scopus 로고
    • Herpesvirus-encoded miRNAs and their roles in viral biology and pathogenesis
    • Zhu Y, Haecker I, Yang Y, Gao S-J, Renne R, (2013) γ-Herpesvirus-encoded miRNAs and their roles in viral biology and pathogenesis. Current opinion in virology 3: 266–275. doi: 10.1016/j.coviro.2013.05.013 23743127
    • (2013) Current opinion in virology , vol.3 , pp. 266-275
    • Zhu, Y.1    Haecker, I.2    Yang, Y.3    Gao, S.-J.4    Renne, R.5
  • 44
    • 77956634358 scopus 로고    scopus 로고
    • Myc is required for the maintenance of Kaposi's sarcoma-associated herpesvirus latency
    • Li X, Chen S, Feng J, Deng H, Sun R, (2010) Myc is required for the maintenance of Kaposi's sarcoma-associated herpesvirus latency. J Virol 84: 8945–8948. doi: 10.1128/JVI.00244-10 20573831
    • (2010) J Virol , vol.84 , pp. 8945-8948
    • Li, X.1    Chen, S.2    Feng, J.3    Deng, H.4    Sun, R.5
  • 46
    • 77950067689 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a
    • Punj V, Matta H, Schamus S, Tamewitz A, Anyang B, et al. (2010) Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a. Oncogene 29: 1835–1844. doi: 10.1038/onc.2009.460 20023696
    • (2010) Oncogene , vol.29 , pp. 1835-1844
    • Punj, V.1    Matta, H.2    Schamus, S.3    Tamewitz, A.4    Anyang, B.5
  • 47
    • 56349103169 scopus 로고    scopus 로고
    • Epstein-Barr virus growth/latency III program alters cellular microRNA expression
    • Cameron JE, Fewell C, Yin Q, McBride J, Wang X, et al. (2008) Epstein-Barr virus growth/latency III program alters cellular microRNA expression. Virology 382: 257–266. doi: 10.1016/j.virol.2008.09.018 18950829
    • (2008) Virology , vol.382 , pp. 257-266
    • Cameron, J.E.1    Fewell, C.2    Yin, Q.3    McBride, J.4    Wang, X.5
  • 48
    • 56649123539 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappaB pathway
    • Gatto G, Rossi A, Rossi D, Kroening S, Bonatti S, et al. (2008) Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappaB pathway. Nucleic Acids Res 36: 6608–6619. doi: 10.1093/nar/gkn666 18940871
    • (2008) Nucleic Acids Res , vol.36 , pp. 6608-6619
    • Gatto, G.1    Rossi, A.2    Rossi, D.3    Kroening, S.4    Bonatti, S.5
  • 49
    • 55249124589 scopus 로고    scopus 로고
    • Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence
    • Lu F, Weidmer A, Liu CG, Volinia S, Croce CM, et al. (2008) Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence. J Virol 82: 10436–10443. doi: 10.1128/JVI.00752-08 18753206
    • (2008) J Virol , vol.82 , pp. 10436-10443
    • Lu, F.1    Weidmer, A.2    Liu, C.G.3    Volinia, S.4    Croce, C.M.5
  • 50
    • 39049139743 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induces the expression of the cellular microRNA miR-146a
    • Motsch N, Pfuhl T, Mrazek J, Barth S, Grasser FA, (2007) Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induces the expression of the cellular microRNA miR-146a. RNA Biology 4: 131–137. 18347435
    • (2007) RNA Biology , vol.4 , pp. 131-137
    • Motsch, N.1    Pfuhl, T.2    Mrazek, J.3    Barth, S.4    Grasser, F.A.5
  • 51
    • 84863993239 scopus 로고    scopus 로고
    • The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells
    • Forte E, Salinas RE, Chang C, Zhou T, Linnstaedt SD, et al. (2012) The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells. J Virol 86: 6889–6898. doi: 10.1128/JVI.07056-11 22496226
    • (2012) J Virol , vol.86 , pp. 6889-6898
    • Forte, E.1    Salinas, R.E.2    Chang, C.3    Zhou, T.4    Linnstaedt, S.D.5
  • 52
    • 84892583254 scopus 로고    scopus 로고
    • Inhibition of interferon gene activation by death-effector domain-containing proteins from the molluscum contagiosum virus
    • Randall CMH, Biswas S, Selen CV, Shisler JL, (2014) Inhibition of interferon gene activation by death-effector domain-containing proteins from the molluscum contagiosum virus. Proc Natl Acad Sci U S A 111: E265–E272. doi: 10.1073/pnas.1314569111 24379396
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 265-272
    • Randall, C.M.H.1    Biswas, S.2    Selen, C.V.3    Shisler, J.L.4
  • 53
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • Derynck R, Akhurst RJ, Balmain A, (2001) TGF-beta signaling in tumor suppression and cancer progression. Nature genetics 29: 117–129. 11586292
    • (2001) Nature genetics , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 54
    • 77549083441 scopus 로고    scopus 로고
    • Transforming growth factor beta (TGF-beta) and inflammation in cancer
    • Bierie B, Moses HL, (2010) Transforming growth factor beta (TGF-beta) and inflammation in cancer. Cytokine & growth factor reviews 21: 49–59.
    • (2010) Cytokine & growth factor reviews , vol.21 , pp. 49-59
    • Bierie, B.1    Moses, H.L.2
  • 56
    • 13544258096 scopus 로고    scopus 로고
    • The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus modulates cellular gene expression and protects lymphoid cells from p16 INK4A-induced cell cycle arrest
    • An FQ, Compitello N, Horwitz E, Sramkoski M, Knudsen ES, et al. (2005) The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus modulates cellular gene expression and protects lymphoid cells from p16 INK4A-induced cell cycle arrest. J Biol Chem 280: 3862–3874. 15525642
    • (2005) J Biol Chem , vol.280 , pp. 3862-3874
    • An, F.Q.1    Compitello, N.2    Horwitz, E.3    Sramkoski, M.4    Knudsen, E.S.5
  • 57
    • 0038305578 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induces expression of the helix-loop-helix protein Id-1 in human endothelial cells
    • Tang J, Gordon GM, Muller MG, Dahiya M, Foreman KE, (2003) Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induces expression of the helix-loop-helix protein Id-1 in human endothelial cells. J Virol 77: 5975–5984. 12719589
    • (2003) J Virol , vol.77 , pp. 5975-5984
    • Tang, J.1    Gordon, G.M.2    Muller, M.G.3    Dahiya, M.4    Foreman, K.E.5
  • 58
    • 77954697250 scopus 로고    scopus 로고
    • Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells
    • Doebele C, Bonauer A, Fischer A, Scholz A, Reiss Y, et al. (2010) Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells. Blood 115: 4944–4950. doi: 10.1182/blood-2010-01-264812 20299512
    • (2010) Blood , vol.115 , pp. 4944-4950
    • Doebele, C.1    Bonauer, A.2    Fischer, A.3    Scholz, A.4    Reiss, Y.5
  • 59
    • 77956522557 scopus 로고    scopus 로고
    • Angiogenesis micromanagement
    • Kuhnert F, Kuo CJ, (2010) miR-17-92 angiogenesis micromanagement. Blood 115: 4631–4633. doi: 10.1182/blood-2010-03-276428 20538815
    • (2010) Blood , vol.115 , pp. 4631-4633
    • Kuhnert, F.1    Kuo, C.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.