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Volumn 18, Issue 3, 2013, Pages 399-408

Cost-effectiveness analysis of UGT1A1 genetic testing to inform antiretroviral prescribing in HIV disease

Author keywords

[No Author keywords available]

Indexed keywords

ATAZANAVIR; DARUNAVIR; EMTRICITABINE; GLUCURONOSYLTRANSFERASE 1A1; RITONAVIR; TENOFOVIR;

EID: 84878098923     PISSN: 13596535     EISSN: 20402058     Source Type: Journal    
DOI: 10.3851/IMP2500     Document Type: Article
Times cited : (11)

References (41)
  • 1
    • 0030030762 scopus 로고    scopus 로고
    • Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome
    • DOI 10.1016/S0140-6736(96)91273-8
    • Monaghan G, Ryan M, Seddon R, Hume R, Burchell B. Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome. Lancet 1996; 347:578-581. (Pubitemid 26070740)
    • (1996) Lancet , vol.347 , Issue.9001 , pp. 578-581
    • Monaghan, G.1    Ryan, M.2    Seddon, R.3    Hume, R.4    Burchell, B.5
  • 2
    • 0028867826 scopus 로고
    • The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
    • Bosma PJ, Chowdhury JR, Bakker C, et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 1995; 333:1171-1175.
    • (1995) N Engl J Med , vol.333 , pp. 1171-1175
    • Bosma, P.J.1    Chowdhury, J.R.2    Bakker, C.3
  • 3
    • 27544468948 scopus 로고    scopus 로고
    • In vitro inhibition of udp glucuronosyltransferases by atazanavir and other HIV protease inhibitors and the relationship of this property to in vivo bilirubin glucuronidation
    • DOI 10.1124/dmd.105.005447
    • Zhang D, Chando TJ, Everett DW, Patten CJ, Dehal SS, Humphreys WG. In vitro inhibition of UDP glucuronosyltransferases by atazanavir and other HIV protease inhibitors and the relationship of this property to in vivo bilirubin glucuronidation. Drug Metab Dispos 2005; 33:1729-1739. (Pubitemid 41539973)
    • (2005) Drug Metabolism and Disposition , vol.33 , Issue.11 , pp. 1729-1739
    • Zhang, D.1    Chando, T.J.2    Everett, D.W.3    Patten, C.J.4    Dehal, S.S.5    Griffith, H.W.6
  • 4
    • 79851482408 scopus 로고    scopus 로고
    • Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: An observational cohort study
    • Lubomirov R, Colombo S, di Iulio J, et al. Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study. J Infect Dis 2011; 203:246-257.
    • (2011) J Infect Dis , vol.203 , pp. 246-257
    • Lubomirov, R.1    Colombo, S.2    Di Iulio, J.3
  • 5
    • 84855616052 scopus 로고    scopus 로고
    • Panel on Antiretroviral Guidelines for Adults and Adolescents. (Updated 27 March 2012. Accessed 6 August 2012.) Available from
    • Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. (Updated 27 March 2012. Accessed 6 August 2012.) Available from http://www.aidsinfo.nih.gov/contentfiles/adultandadolescentGL.pdf
    • Guidelines for the Use of Antiretroviral Agents in HIV-1-infected Adults and Adolescents
  • 6
    • 53549095195 scopus 로고    scopus 로고
    • The cost-effectiveness of HLA-B*5701 genetic screening to guide initial antiretroviral therapy for HIV
    • Schackman BR, Scott CA, Walensky RP, Losina E, Freedberg KA, Sax PE. The cost-effectiveness of HLA-B*5701 genetic screening to guide initial antiretroviral therapy for HIV. AIDS 2008; 22:2025-2033.
    • (2008) AIDS , vol.22 , pp. 2025-2033
    • Schackman, B.R.1    Scott, C.A.2    Walensky, R.P.3    Losina, E.4    Freedberg, K.A.5    Sax, P.E.6
  • 7
    • 84255190568 scopus 로고    scopus 로고
    • Pharmacogenomics of HIV therapy: Summary of a workshop sponsored by the National Institute of Allergy and Infectious Diseases
    • Haas DW, Kuritzkes DR, Ritchie MD, et al. Pharmacogenomics of HIV therapy: summary of a workshop sponsored by the National Institute of Allergy and Infectious Diseases. HIV Clin Trials 2011; 12:277-285.
    • (2011) HIV Clin Trials , vol.12 , pp. 277-285
    • Haas, D.W.1    Kuritzkes, D.R.2    Ritchie, M.D.3
  • 8
    • 69249104215 scopus 로고    scopus 로고
    • Cost effectiveness of pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 before irinotecan administration for metastatic colorectal cancer
    • Gold HT, Hall MJ, Blinder V, Schackman BR. Cost effectiveness of pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 before irinotecan administration for metastatic colorectal cancer. Cancer 2009; 115:3858-3867.
    • (2009) Cancer , vol.115 , pp. 3858-3867
    • Gold, H.T.1    Hall, M.J.2    Blinder, V.3    Schackman, B.R.4
  • 11
    • 84858259555 scopus 로고    scopus 로고
    • Cost-effectiveness of adding an agent that improves immune responses to initial antiretroviral therapy (ART) in HIV-infected patients: Guidance for drug development
    • Morris BL, Scott CA, Wilkin TJ, et al . Cost-effectiveness of adding an agent that improves immune responses to initial antiretroviral therapy (ART) in HIV-infected patients: guidance for drug development. HIV Clin Trials 2012; 13: 1-10.
    • (2012) HIV Clin Trials , vol.13 , pp. 1-10
    • Morris, B.L.1    Scott, C.A.2    Wilkin, T.J.3    Al, E.4
  • 13
    • 52649156033 scopus 로고    scopus 로고
    • Quantifying the decrement in utility from perceived side effects of combination antiretroviral therapies in patients with HIV
    • Braithwaite RS, Goulet J, Kudel I, Tsevat J, Justice AC. Quantifying the decrement in utility from perceived side effects of combination antiretroviral therapies in patients with HIV. Value Health 2008; 11:975-979.
    • (2008) Value Health , vol.11 , pp. 975-979
    • Braithwaite, R.S.1    Goulet, J.2    Kudel, I.3    Tsevat, J.4    Justice, A.C.5
  • 16
    • 0032515391 scopus 로고    scopus 로고
    • The cost-effectiveness of preventing AIDS-related opportunistic infections
    • Freedberg KA, Scharfstein JA, Seage GR, III, et al. The cost-effectiveness of preventing AIDS-related opportunistic infections. JAMA 1998; 279:130-136.
    • (1998) JAMA , vol.279 , pp. 130-136
    • Freedberg, K.A.1    Scharfstein, J.A.2    Seage III, G.R.3
  • 17
    • 0004152165 scopus 로고
    • Release P04. Springfield: National Technical Information Service
    • Multicenter AIDS Cohort Study (MACS) Public Dataset. Release P04. Springfield: National Technical Information Service 1995.
    • (1995) Multicenter AIDS Cohort Study (MACS) Public Dataset
  • 18
    • 65549121051 scopus 로고    scopus 로고
    • Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: Recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America
    • Kaplan JE, Benson C, Holmes KH, et al. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. MMWR Recomm Rep 2009; 58:1-207.
    • (2009) MMWR Recomm Rep , vol.58 , pp. 1-207
    • Kaplan, J.E.1    Benson, C.2    Holmes, K.H.3
  • 19
    • 70349580829 scopus 로고    scopus 로고
    • United Nations, Department of Economic and Social Affairs, Population Division. Working paper number. ESA/P/WP.210
    • United Nations, Department of Economic and Social Affairs, Population Division. World population prospects: the 2008 revision, highlights. Working paper number. ESA/P/WP.210. 2009.
    • (2009) World Population Prospects: The 2008 Revision, Highlights
  • 21
    • 79955440277 scopus 로고    scopus 로고
    • Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1
    • Daar ES, Tierney C, Fischl MA, et al . Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1. Ann Intern Med 2011; 154: 445-456.
    • (2011) Ann Intern Med , vol.154 , pp. 445-456
    • Daar, E.S.1    Tierney, C.2    Fischl, M.A.3
  • 24
    • 34147136222 scopus 로고    scopus 로고
    • Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: A phase II randomised controlled trial
    • DOI 10.1016/S0140-6736(07)60597-2, PII S0140673607605972
    • Grinsztejn B, Nguyen BY, Katlama C, et al. Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a Phase II randomised controlled trial. Lancet 2007; 369:1261-1269. (Pubitemid 46553846)
    • (2007) Lancet , vol.369 , Issue.9569 , pp. 1261-1269
    • Grinsztejn, B.1    Nguyen, B.-Y.2    Katlama, C.3    Gatell, J.M.4    Lazzarin, A.5    Vittecoq, D.6    Gonzalez, C.J.7    Chen, J.8    Harvey, C.M.9    Isaacs, R.D.10
  • 25
    • 54849146700 scopus 로고    scopus 로고
    • Maraviroc for previously treated patients with R5 HIV-1 infection
    • Gulick RM, Lalezari J, Goodrich J, et al. Maraviroc for previously treated patients with R5 HIV-1 infection. N Engl J Med 2008; 359:1429-1441.
    • (2008) N Engl J Med , vol.359 , pp. 1429-1441
    • Gulick, R.M.1    Lalezari, J.2    Goodrich, J.3
  • 26
    • 78149428813 scopus 로고    scopus 로고
    • Montvale, NJ: Thomson PDR
    • Shenouda N. Red Book. Montvale, NJ: Thomson PDR 2009.
    • (2009) Red Book
    • Shenouda, N.1
  • 27
    • 82555199574 scopus 로고    scopus 로고
    • Office of Inspector General. (Updated 1 June 2005. Accessed 29 August 2012.) Available from
    • Department of Health and Human Services. Office of Inspector General. Medicaid drug price comparisons: average manufacturer price to published prices. (Updated 1 June 2005. Accessed 29 August 2012.) Available from http://oig.hhs.gov/oei/reports/oei-05-05-00240.pdf
    • Medicaid Drug Price Comparisons: Average Manufacturer Price to Published Prices
  • 28
    • 72849122861 scopus 로고    scopus 로고
    • Racial and sex disparities in life expectancy losses among HIV-infected persons in the United States: Impact of risk behavior, late initiation, and early discontinuation of antiretroviral therapy
    • Losina E, Schackman BR, Sadownik SN, et al. Racial and sex disparities in life expectancy losses among HIV-infected persons in the United States: impact of risk behavior, late initiation, and early discontinuation of antiretroviral therapy. Clin Infect Dis 2009; 49:1570-1578.
    • (2009) Clin Infect Dis , vol.49 , pp. 1570-1578
    • Losina, E.1    Schackman, B.R.2    Sadownik, S.N.3
  • 29
    • 18744385081 scopus 로고    scopus 로고
    • (Updated 27 March 2012. Accessed 6 August 2012.) Available from
    • Centers for Medicare and Medicaid Services. Medicare physician fee schedule. (Updated 27 March 2012. Accessed 6 August 2012.) Available from https://www.cms.gov/apps/physician-fee-schedule/
    • Medicare Physician Fee Schedule
  • 30
    • 1442334891 scopus 로고    scopus 로고
    • The HIV Research Network: A unique opportunity for real time clinical utilization analysis in HIV
    • Gebo KA, Moore RD, Fleishman JA. The HIV Research Network: a unique opportunity for real time clinical utilization analysis in HIV. Hopkins HIV Rep 2003; 15:5-6.
    • (2003) Hopkins HIV Rep , vol.15 , pp. 5-6
    • Gebo, K.A.1    Moore, R.D.2    Fleishman, J.A.3
  • 31
    • 84859461301 scopus 로고    scopus 로고
    • (Updated 23 March 2012. Accessed 6 August 2012.) Available from
    • Centers for Medicare and Medicaid Services. Clinical laboratory fee schedule. (Updated 23 March 2012. Accessed 6 August 2012.) Available from http://www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/ ClinicalLabFeeSched/clinlab.html
    • Clinical Laboratory Fee Schedule
  • 32
    • 0032718482 scopus 로고    scopus 로고
    • Variability at the uridine diphosphate glucuronosyltransferase 1A1 promoter in human populations and primates
    • Hall D, Ybazeta G, Destro-Bisol G, Petzl-Erler ML, Di Rienzo A. Variability at the uridine diphosphate glucuronosyltransferase 1A1 promoter in human populations and primates. Pharmacogenetics 1999; 9: 591-599.
    • (1999) Pharmacogenetics , vol.9 , pp. 591-599
    • Hall, D.1    Ybazeta, G.2    Destro-Bisol, G.3    Petzl-Erler, M.L.4    Di Rienzo, A.5
  • 34
  • 35
    • 79953775351 scopus 로고    scopus 로고
    • Linkage and retention in HIV care among men who have sex with men in the United States
    • Christopoulos KA, Das M, Colfax GN. Linkage and retention in HIV care among men who have sex with men in the United States. Clin Infect Dis 2011; 52 Suppl 2:S214-S222.
    • (2011) Clin Infect Dis , vol.52 , Issue.SUPPL. 2
    • Christopoulos, K.A.1    Das, M.2    Colfax, G.N.3
  • 36
    • 76749150900 scopus 로고    scopus 로고
    • Retaining HIV-infected patients in care: Where are we? Where do we go from here?
    • Horstmann E, Brown J, Islam F, Buck J, Agins BD. Retaining HIV-infected patients in care: where are we? Where do we go from here? Clin Infect Dis 2010; 50:752-761.
    • (2010) Clin Infect Dis , vol.50 , pp. 752-761
    • Horstmann, E.1    Brown, J.2    Islam, F.3    Buck, J.4    Agins, B.D.5
  • 37
    • 82855160980 scopus 로고    scopus 로고
    • Vital signs: HIV prevention through care and treatment - United States
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. Vital signs: HIV prevention through care and treatment - United States. MMWR Morb Mortal Wkly Rep 2011; 60:1618-1623.
    • (2011) MMWR Morb Mortal Wkly Rep , vol.60 , pp. 1618-1623
  • 38
    • 79951811383 scopus 로고    scopus 로고
    • The emerging role of electronic medical records in pharmacogenomics
    • Wilke RA, Xu H, Denny JC, et al. The emerging role of electronic medical records in pharmacogenomics. Clin Pharmacol Ther 2011; 89:379-386.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 379-386
    • Wilke, R.A.1    Xu, H.2    Denny, J.C.3
  • 40
    • 84878040395 scopus 로고    scopus 로고
    • Bristol-Myers Squibb, Gilead Sciences, Merck, Tibotec Therapeutics
    • AIDS Clinical Trials Group, National Institute of Allergy and Infectious Diseases (NIAID), (Updated 6 October 2011. Accessed 22 May 2012.) Available from
    • AIDS Clinical Trials Group, National Institute of Allergy and Infectious Diseases (NIAID), Bristol-Myers Squibb, Gilead Sciences, Merck, Tibotec Therapeutics. Comparative study of three NNRTI-sparing HAART regimens. (Updated 6 October 2011. Accessed 22 May 2012.) Available from http://clinicaltrials.gov/ ct2/show/NCT00811954?term=NCT00811954&rank=1
    • Comparative Study of Three NNRTI-sparing HAART Regimens
  • 41
    • 0036150570 scopus 로고    scopus 로고
    • Comparison of health state utilities using community and patient preference weights derived from a survey of patients with HIV/AIDS
    • DOI 10.1177/02729890222062892
    • Schackman BR, Goldie SJ, Freedberg KA, Losina E, Brazier J, Weinstein MC. Comparison of health state utilities using community and patient preference weights derived from a survey of patients with HIV/AIDS. Med Decis Making 2002; 22:27-38. (Pubitemid 34087688)
    • (2002) Medical Decision Making , vol.22 , Issue.1 , pp. 27-38
    • Schackman, B.R.1    Goldie, S.J.2    Freedberg, K.A.3    Losina, E.4    Brazier, J.5    Weinstein, M.C.6


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