Selenium metabolism to the trimethylselenonium ion (TMSe) varies markedly because of polymorphisms in the indolethylamine N-methyltransferase gene

American Journal of Clinical Nutrition

Volumn 102, Issue 6, 2015, Pages 1406-1415

  Kuehnelt, Doris ^a,d   Engström, Karin ^b,d   Skröder, Helena ^c   Kokarnig, Sabine ^a   Schlebusch, Carina ^d   Kippler, Maria ^c   Alhamdow, Ayman ^b   Nermell, Barbro ^c   Francesconi, Kevin ^a   Broberg, Karin ^b,c   Vahter, Marie ^c  

^a UNIVERSITY OF GRAZ   (Austria)

^b LUND UNIVERSITY   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

Child; Essential; Excretion; Human urine; Metabolite; Methylation; Population differences; Rs1061644; Rs4270015; Rs6970396; Selenium

Indexed keywords

HEMOGLOBIN; INDOLETHYLAMINE N METHYLTRANSFERASE; METHYLTRANSFERASE; SELENIUM; TRIMETHYLSELENONIUM ION; UNCLASSIFIED DRUG; ISOENZYME; SELENIUM DERIVATIVE; TRIMETHYLSELENONIUM; TRYPTAMINE N-METHYLTRANSFERASE;

ADULT; ARTICLE; BANGLADESH; CHILD; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEMOGLOBIN DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; KIDNEY CONCENTRATING CAPACITY; MASS SPECTROMETRY; METABOLISM; SELENIUM BLOOD LEVEL; SELENIUM URINE LEVEL; SINGLE NUCLEOTIDE POLYMORPHISM; URINALYSIS; URINE LEVEL; ARGENTINA; BLOOD; CHILD NUTRITION; COHORT ANALYSIS; DEFICIENCY; GENETICS; HEALTH; MALE; MATERNAL NUTRITION; NUTRITIONAL DEFICIENCY; NUTRITIONAL STATUS; PREGNANCY; PREGNANCY COMPLICATION; PRESCHOOL CHILD; URINARY EXCRETION; URINE; VALIDATION STUDY;

ADULT; ARGENTINA; BANGLADESH; CHILD NUTRITIONAL PHYSIOLOGICAL PHENOMENA; CHILD, PRESCHOOL; COHORT STUDIES; DEFICIENCY DISEASES; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; ISOENZYMES; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; METHYLTRANSFERASES; NUTRITIONAL STATUS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PREGNANCY COMPLICATIONS; RENAL ELIMINATION; RURAL HEALTH; SELENIUM; SELENIUM COMPOUNDS;

EID: 84948845309     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.115.114157     Document Type: Article

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