-
1
-
-
70149106164
-
HIF-2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses
-
Bertout JA, Majmundar AJ, Gordan JD, Lam JC, Ditsworth D, Keith B, Brown EJ, Nathanson KL, and Simon MC. HIF-2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses. Proc Natl Acad Sci U S A 106: 14391-14396, 2009.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14391-14396
-
-
Bertout, J.A.1
Majmundar, A.J.2
Gordan, J.D.3
Lam, J.C.4
Ditsworth, D.5
Keith, B.6
Brown, E.J.7
Nathanson, K.L.8
Simon, M.C.9
-
2
-
-
34247250752
-
NAD(P)H oxidases regulate HIF-2alpha protein expression
-
DOI 10.1074/jbc.M611569200
-
Block K, Gorin Y, Hoover P, Williams P, Chelmicki T, Clark RA, Yoneda T, and Abboud HE. NAD(P)H oxidases regulate HIF-2alpha protein expression. J Biol Chem 282: 8019-8026, 2007. (Pubitemid 47093603)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.11
, pp. 8019-8026
-
-
Block, K.1
Gorin, Y.2
Hoover, P.3
Williams, P.4
Chelmicki, T.5
Clark, R.A.6
Yoneda, T.7
Abboud, H.E.8
-
3
-
-
0032573495
-
Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu
-
DOI 10.1016/S0014-5793(98)01410-0, PII S0014579398014100
-
Clement MV, Ponton A, and Pervaiz S. Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu. FEBS Lett 440: 13-18, 1998. (Pubitemid 28558725)
-
(1998)
FEBS Letters
, vol.440
, Issue.1-2
, pp. 13-18
-
-
Clement, M.-V.1
Ponton, A.2
Pervaiz, S.3
-
4
-
-
77953520763
-
The Hypoxia-inducible Factor-2alpha Is Stabilized by Oxidative Stress Involving NOX4
-
Diebold I, Flugel D, Becht S, Belaiba RS, Bonello S, Hess J, Kietzmann T, and Gorlach A. The Hypoxia-inducible Factor-2alpha Is Stabilized by Oxidative Stress Involving NOX4. Antioxid Redox Signal.
-
Antioxid Redox Signal
-
-
Diebold, I.1
Flugel, D.2
Becht, S.3
Belaiba, R.S.4
Bonello, S.5
Hess, J.6
Kietzmann, T.7
Gorlach, A.8
-
5
-
-
20244370600
-
Intrinsic chemotherapy resistance to the tubulin-binding antimitotic agents in renal cell carcinoma
-
DOI 10.1002/ijc.20816
-
Ferguson RE, Jackson SM, Stanley AJ, Joyce AD, Harnden P, Morrison EE, Patel PM, Phillips RM, Selby PJ, and Banks RE. Intrinsic chemotherapy resistance to the tubulin-binding antimitotic agents in renal cell carcinoma. Int J Cancer 115: 155-163, 2005. (Pubitemid 40559682)
-
(2005)
International Journal of Cancer
, vol.115
, Issue.1
, pp. 155-163
-
-
Ferguson, R.E.1
Jackson, S.M.2
Stanley, A.J.3
Joyce, A.D.4
Harnden, P.5
Morrison, E.E.6
Patel, P.M.7
Phillips, R.M.8
Selby, P.J.9
Banks, R.E.10
-
6
-
-
33750919240
-
NADPH oxidases in the kidney
-
DOI 10.1089/ars.2006.8.1597
-
Gill PS, and Wilcox CS. NADPH oxidases in the kidney. Antioxid Redox Signal 8: 1597-1607, 2006. (Pubitemid 44726334)
-
(2006)
Antioxidants and Redox Signaling
, vol.8
, Issue.9-10
, pp. 1597-1607
-
-
Gill, P.S.1
Wilcox, C.S.2
-
8
-
-
9144257277
-
Tissue distribution and putative physiological function of NOX family NADPH oxidases
-
Krause KH. Tissue distribution and putative physiological function of NOX family NADPH oxidases. Jpn J Infect Dis 57: S28-29, 2004.
-
(2004)
Jpn J Infect Dis
, vol.57
-
-
Krause, K.H.1
-
9
-
-
33748061638
-
Protective role of L-2-oxothiazolidine-4-carboxylic acid in cisplatin-induced renal injury
-
DOI 10.1093/ndt/gfl209
-
Lee S, Moon SO, Kim W, Sung MJ, Kim DH, Kang KP, Jang YB, Lee JE, Jang KY, Lee SY, and Park SK. Protective role of L-2-oxothiazolidine-4-carboxylic acid in cisplatin-induced renal injury. Nephrol Dial Transplant 21: 2085-2095, 2006. (Pubitemid 44295033)
-
(2006)
Nephrology Dialysis Transplantation
, vol.21
, Issue.8
, pp. 2085-2095
-
-
Lee, S.1
Moon, S.-O.2
Kim, W.3
Sung, M.J.4
Kim, D.H.5
Kang, K.P.6
Jang, Y.B.7
Lee, J.E.8
Jang, K.Y.9
Lee, S.Y.10
Park, S.K.11
-
10
-
-
4544229590
-
Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination
-
DOI 10.1111/j.1349-7006.2004.tb03323.x
-
Li D, Ueta E, Kimura T, Yamamoto T, and Osaki T. Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination. Cancer Sci 95: 644-650, 2004. (Pubitemid 39255811)
-
(2004)
Cancer Science
, vol.95
, Issue.8
, pp. 644-650
-
-
Li, D.1
Ueta, E.2
Kimura, T.3
Yamamoto, T.4
Osaki, T.5
-
11
-
-
78349272461
-
HIF-1 and HIF-2 transcription factors - Similar but not identical
-
Loboda A, Jozkowicz A, and Dulak J. HIF-1 and HIF-2 transcription factors - similar but not identical. Molecules and cells 29: 435-442.
-
Molecules and Cells
, vol.29
, pp. 435-442
-
-
Loboda, A.1
Jozkowicz, A.2
Dulak, J.3
-
12
-
-
0036527785
-
The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma
-
DOI 10.1016/S1535-6108(02)00044-2
-
Maranchie JK, Vasselli JR, Riss J, Bonifacino JS, Linehan WM, and Klausner RD. The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma. Cancer Cell 1: 247-255, 2002. (Pubitemid 41039149)
-
(2002)
Cancer Cell
, vol.1
, Issue.3
, pp. 247-255
-
-
Maranchie, J.K.1
Vasselli, J.R.2
Riss, J.3
Bonifacino, J.S.4
Linehan, W.M.5
Klausner, R.D.6
-
13
-
-
27144444002
-
Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma
-
DOI 10.1158/0008-5472.CAN-05-2105
-
Maranchie JK, and Zhan Y. Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma. Cancer Res 65: 9190-9193, 2005. (Pubitemid 41507983)
-
(2005)
Cancer Research
, vol.65
, Issue.20
, pp. 9190-9193
-
-
Maranchie, J.K.1
Zhan, Y.2
-
14
-
-
0034900409
-
Screening for and identification of novel agents directed at renal cell carcinoma
-
Mertins SD, Myers TG, Hollingshead M, Dykes D, Bodde E, Tsai P, Jefferis CA, Gupta R, Linehan WM, Alley M, and Bates SE. Screening for and identification of novel agents directed at renal cell carcinoma. Clin Cancer Res 7: 620-633, 2001. (Pubitemid 32707988)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.3
, pp. 620-633
-
-
Mertins, S.D.1
Myers, T.G.2
Hollingshead, M.3
Dykes, D.4
Bodde, E.5
Tsai, P.6
Jefferis, C.A.7
Gupta, R.8
Linehan, W.M.9
Alley, M.10
Bates, S.E.11
-
15
-
-
33745518361
-
Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells
-
DOI 10.1038/sj.onc.1209406, PII 1209406
-
Mochizuki T, Furuta S, Mitsushita J, Shang WH, Ito M, Yokoo Y, Yamaura M, Ishizone S, Nakayama J, Konagai A, Hirose K, Kiyosawa K, and Kamata T. Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells. Oncogene 25: 3699-3707, 2006. (Pubitemid 43980491)
-
(2006)
Oncogene
, vol.25
, Issue.26
, pp. 3699-3707
-
-
Mochizuki, T.1
Furuta, S.2
Mitsushita, J.3
Shang, W.H.4
Ito, M.5
Yokoo, Y.6
Yamaura, M.7
Ishizone, S.8
Nakayama, J.9
Konagai, A.10
Hirose, K.11
Kiyosawa, K.12
Kamata, T.13
-
16
-
-
0028596392
-
Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscle
-
Mohazzab KM, and Wolin MS. Sites of superoxide anion production detected by lucigenin in calf pulmonary artery smooth muscle. The American journal of physiology 267: L815-822, 1994.
-
(1994)
The American Journal of Physiology
, vol.267
-
-
Mohazzab, K.M.1
Wolin, M.S.2
-
17
-
-
0033978220
-
Systemic therapy for renal cell carcinoma
-
Motzer RJ, and Russo P. Systemic therapy for renal cell carcinoma. J Urol 163: 408-417, 2000. (Pubitemid 30060482)
-
(2000)
Journal of Urology
, vol.163
, Issue.2
, pp. 408-417
-
-
Motzer, R.J.1
Russo, P.2
-
18
-
-
0033736398
-
Molecular analysis of mechanisms regulating drug sensitivity and the development of new chemotherapy strategies for genitourinary carcinomas
-
Naito S, Koga H, Yokomizo A, Sakamoto N, Kotoh S, Nakashima M, Kiue A, and Kuwano M. Molecular analysis of mechanisms regulating drug sensitivity and the development of new chemotherapy strategies for genitourinary carcinomas. World journal of surgery 24: 1183-1186, 2000.
-
(2000)
World Journal of Surgery
, vol.24
, pp. 1183-1186
-
-
Naito, S.1
Koga, H.2
Yokomizo, A.3
Sakamoto, N.4
Kotoh, S.5
Nakashima, M.6
Kiue, A.7
Kuwano, M.8
-
19
-
-
22944451161
-
Involvement of ABC transporters in chemosensitivity of human renal cell carcinoma, and regulation of MRP2 expression by conjugated bilirubin
-
Nomura M, Matsunami T, Kobayashi K, Uchibayashi T, Koshida K, Tanaka M, Namiki M, Mizuhara Y, Akiba T, Yokogawa K, Moritani S, and Miyamoto K. Involvement of ABC transporters in chemosensitivity of human renal cell carcinoma, and regulation of MRP2 expression by conjugated bilirubin. Anticancer Res 25: 2729-2735, 2005.
-
(2005)
Anticancer Res
, vol.25
, pp. 2729-2735
-
-
Nomura, M.1
Matsunami, T.2
Kobayashi, K.3
Uchibayashi, T.4
Koshida, K.5
Tanaka, M.6
Namiki, M.7
Mizuhara, Y.8
Akiba, T.9
Yokogawa, K.10
Moritani, S.11
Miyamoto, K.12
-
21
-
-
20744445650
-
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
-
DOI 10.1128/MCB.25.13.5675-5686.2005
-
Raval RR, Lau KW, Tran MG, Sowter HM, Mandriota SJ, Li JL, Pugh CW, Maxwell PH, Harris AL, and Ratcliffe PJ. Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol Cell Biol 25: 5675-5686, 2005. (Pubitemid 40853601)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.13
, pp. 5675-5686
-
-
Raval, R.R.1
Lau, K.W.2
Tran, M.G.B.3
Sowter, H.M.4
Mandriota, S.J.5
Li, J.-L.6
Pugh, C.W.7
Maxwell, P.H.8
Harris, A.L.9
Ratcliffe, P.J.10
-
22
-
-
33645535119
-
VEGF-targeted therapy in renal cell carcinoma: Active drugs and active choices
-
Rini BI. VEGF-targeted therapy in renal cell carcinoma: active drugs and active choices. Current oncology reports 8: 85-89, 2006.
-
(2006)
Current Oncology Reports
, vol.8
, pp. 85-89
-
-
Rini, B.I.1
-
23
-
-
0033538545
-
Thiols mediate superoxide-dependent NADH modification of glyceraldehyde-3-phosphate dehydrogenase
-
Rivera-Nieves J, Thompson WC, Levine RL, and Moss J. Thiols mediate superoxide-dependent NADH modification of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem 274: 19525-19531, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 19525-19531
-
-
Rivera-Nieves, J.1
Thompson, W.C.2
Levine, R.L.3
Moss, J.4
-
24
-
-
71549151624
-
Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells
-
Roberts AM, Watson IR, Evans AJ, Foster DA, Irwin MS, and Ohh M. Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells. Cancer Res 69: 9056-9064, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 9056-9064
-
-
Roberts, A.M.1
Watson, I.R.2
Evans, A.J.3
Foster, D.A.4
Irwin, M.S.5
Ohh, M.6
-
25
-
-
0035985610
-
Expression of multidrug resistance-associated protein 2 (MRP2) in normal human tissues and carcinomas using tissue microarrays
-
DOI 10.1046/j.1365-2559.2002.01403.x
-
Sandusky GE, Mintze KS, Pratt SE, and Dantzig AH. Expression of multidrug resistance-associated protein 2 (MRP2) in normal human tissues and carcinomas using tissue microarrays. Histopathology 41: 65-74, 2002. (Pubitemid 34779683)
-
(2002)
Histopathology
, vol.41
, Issue.1
, pp. 65-74
-
-
Sandusky, G.E.1
Mintze, K.S.2
Pratt, S.E.3
Dantzig, A.H.4
-
26
-
-
47049099187
-
Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival
-
DOI 10.1002/ijc.23569
-
Shono T, Yokoyama N, Uesaka T, Kuroda J, Takeya R, Yamasaki T, Amano T, Mizoguchi M, Suzuki SO, Niiro H, Miyamoto K, Akashi K, Iwaki T, Sumimoto H, and Sasaki T. Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival. Int J Cancer 123: 787-792, 2008. (Pubitemid 352032403)
-
(2008)
International Journal of Cancer
, vol.123
, Issue.4
, pp. 787-792
-
-
Shono, T.1
Yokoyama, N.2
Uesaka, T.3
Kuroda, J.4
Takeya, R.5
Yamasaki, T.6
Amano, T.7
Mizoguchi, M.8
Suzuki, S.O.9
Niiro, H.10
Miyamoto, K.11
Akashi, K.12
Iwaki, T.13
Sumimoto, H.14
Sasaki, T.15
-
28
-
-
51749088156
-
Redox regulation of cell survival
-
Trachootham D, Lu W, Ogasawara MA, Nilsa RD, and Huang P. Redox regulation of cell survival. Antioxid Redox Signal 10: 1343-1374, 2008.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 1343-1374
-
-
Trachootham, D.1
Lu, W.2
Ogasawara, M.A.3
Nilsa, R.D.4
Huang, P.5
-
29
-
-
4544250814
-
Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells
-
DOI 10.1074/jbc.M400078200
-
Vaquero EC, Edderkaoui M, Pandol SJ, Gukovsky I, and Gukovskaya AS. Reactive oxygen species produced by NAD(P) H oxidase inhibit apoptosis in pancreatic cancer cells. J Biol Chem 279: 34643-34654, 2004. (Pubitemid 39318094)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34643-34654
-
-
Vaquero, E.C.1
Edderkaoui, M.2
Pandol, S.J.3
Gukovsky, I.4
Gukovskaya, A.S.5
-
30
-
-
33749639540
-
Prevention of cisplatin-induced kidney epithelial cell apoptosis with a Cu superoxide dismutase-mimetic [copper(2)(II)(3,5-ditertiarybutylsalicylate)(4) (ethanol)(4)]
-
Wangila GW, Nagothu KK, Steward R, 3rd, Bhatt R, Iyere PA, Willingham WM, Sorenson JR, Shah SV, and Portilla D. Prevention of cisplatin-induced kidney epithelial cell apoptosis with a Cu superoxide dismutase-mimetic [copper(2)(II)(3,5-ditertiarybutylsalicylate)(4)(ethanol)(4)]. Toxicol In Vitro 20: 1300-1312, 2006.
-
(2006)
Toxicol in Vitro
, vol.20
, pp. 1300-1312
-
-
Wangila, G.W.1
Nagothu, K.K.2
Steward III, R.3
Bhatt, R.4
Iyere, P.A.5
Willingham, W.M.6
Sorenson, J.R.7
Shah, S.V.8
Portilla, D.9
|