Significant association of caveolin-1 and caveolin-2 with prostate cancer progression

Cancer Genomics and Proteomics

Volumn 12, Issue 6, 2015, Pages 391-396

  Sugie, Satoru ^a   Mukai, Shoichiro ^a   Yamasaki, Koji ^a   Kamibeppu, Toyoharu ^a   Tsukino, Hiromasa ^a   Kamoto, Toshiyuki ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Caveolin 1; Caveolin 2; Prostate cancer progression

Indexed keywords

CAVEOLIN 1; CAVEOLIN 2; MESSENGER RNA; SMALL INTERFERING RNA; CAV1 PROTEIN, HUMAN; CAV2 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CANCER GROWTH; CANCER STAGING; CASTRATION RESISTANT PROSTATE CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GLEASON SCORE; HUMAN; HUMAN CELL; JAPANESE (PEOPLE); LNCAP CELL LINE; MALE; PROSTATE CANCER; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; BLOOD; DISEASE COURSE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; JAPAN; MIDDLE AGED; PATHOLOGY; PROSTATE TUMOR; RETROSPECTIVE STUDY; TUMOR CELL LINE; UPREGULATION;

AGED; CAVEOLIN 1; CAVEOLIN 2; CELL LINE, TUMOR; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; JAPAN; MALE; MIDDLE AGED; NEOPLASM STAGING; PROSTATIC NEOPLASMS; PROSTATIC NEOPLASMS, CASTRATION-RESISTANT; RETROSPECTIVE STUDIES; UP-REGULATION;

EID: 84948757574     PISSN: 11096535     EISSN: 17906245     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Committee for Establishment of the Guidelines on Screening for Prostate Cancer: Japanese Urological Association: Updated Japanese Urological Association Guidelines on prostate-specific antigen-based screening for prostate cancer in 2010. Int J Urol 17(10):830-838, 2010.
2. Scherer PE, Lewis RY, Volonte D, Engelman JA, Galbiati F, Couet J, Kohtz DS, Van Donselaar E, Peters P and Lisanti MP: Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable heterooligomeric complex in vivo. J Biol Chem 272:29337-29346, 1997.
3. Yang G, Goltsov AA, Ren C, Kurosaka S, Edamura K, Logothetis R, De Mayo FJ, Troncoso P, Blando J, Di Giovanni J and Thompson TC: Caveolin-1 up-regulation contributes to c-Myc-induced high-grade prostatic intraepithelial neoplasia and prostate cancer. Mol Cancer Res 10:218-29, 2012.
4. Williams TM, Hassan GS, Li J, Cohen AW, Medina F, Frank PG, Pestell RG, Di Vizio D, Loda M and Lisanti MP: Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of CAV1 delays advanced prostate tumor development in tramp mice. J Biol Chem 280:25134-25145, 2005.
5. Sugie S, Mukai S, Tsukino H, Toda Y, Yamauchi T, Nishikata I, Kuroda Y, Morishita K and Kamoto T: Increased plasma caveolin-1 levels are associated with progression of prostate cancer among Japanese Men. Anticancer Res 33(5):1893-1897, 2013.
6. Suzuoki M, Miyamoto M, Kato K, Hiraoka K, Oshikiri T, Nakakubo Y, Fukunaga A, Shichinohe T, Shinohara T, Itoh T, Kondo S and Katoh H: Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma. Br J Cancer 87:1140-1144, 2002.
7. Chatterjee M, Ben-Josef E, Thomas DG, Morgan MA, Zalupski MM, Khan G, Andrew Robinson C, Griffith KA, Chen CS, Ludwig T, Bekaii-Saab T, Chakravarti A and Williams TM: caveolin-1 is associated with tumor progression and confers a multi-modality resistance phenotype in pancreatic cancer. Sci Rep 12; 5:10867, 2015.
8. Fine SW, Lisanti MP, Galbiati F and Li M: Elevated expression of caveolin-1 in adenocarcinoma of the colon. Am J Clin Pathol 115:719-724, 2001.
9. Basu Roy UK, Henkhaus RS, Loupakis F, Cremolini C, Gerner EW and Ignatenko NA: Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis. Int J Cancer 133(1):43-57, 2013.
10. Van Den Eynden GG, Van Laere SJ, Van Der Auwera I, Merajver SD, Van Marck EA, Van Dam P, Vermeulen PB, Dirix LY and Van Golen KL: Overexpression of caveolin-1 and-2 in cell lines and in human samples of inflammatory breast cancer. Breast Cancer Res Treat 95:219-228, 2006.
11. Kato K, Hida Y, Miyamoto M, Hashida H, Shinohara T, Itoh T, Okushiba S, Kondo S and Katoh H: Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage. Cancer 94:929-933, 2002.
12. Ando T, Ishiguro H, Kimura M, Mitsui A, Mori Y, Sugito N, Tomoda K, Mori R, Harada K, Katada T, Ogawa R, Fujii Y and Kuwabara Y: The overexpression of caveolin-1 and caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma. Oncol Rep 18(3):601-609, 2007.
13. Wikman H, Seppanen JK, Sarhadi VK, Kettunen E, Salmenkivi K, Kuosma E, Vainio-Siukola K, Nagy B, Karjalainen A, Sioris T, Salo J, Hollmen J, Knuutila S and Anttila S: Caveolins as tumor markers in lung cancer detected by combined use of cDNA and tissue microarrays. J Pathol 203:584-593, 2004.
14. Bender FC, Reymond MA, Bron C and Quest AF: Caveolin-1 levels are down-regulated in human colon tumors, and ectopic expression of caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity. Cancer Res 60:5870-5878, 2000.
15. Nimri L, Barak H, Graeve L and Schwartz B: Restoration of caveolin-1 expression suppresses growth, membrane-type-4 metalloproteinase expression and metastasis-associated activities in colon cancer cells. Mol Carcinog 52(11):859-870, 2013.
16. Davidson B, Nesland JM, Goldberg I, Kopolovic J, Gotlieb WH, Bryne M, Ben-Baruch G, Berner A and Reich R: Caveolin-1 expression in advanced-stage ovarian carcinoma - a clinicopathologic study. Gynecol Oncol 81:166-171, 2001.
17. Sagara Y, Mimori K, Yoshinaga K, Tanaka F, Nishida K, Ohno S, Inoue H and Mori M: Clinical significance of caveolin-1, caveolin-2 and HER2/neu mRNA expression in human breast cancer. Br J Cancer 91:959-965, 2004.
18. Sloan EK, Stanley KL and Anderson RL: Caveolin-1 inhibits breast cancer growth and metastasis. Oncogene 23:7893-7897, 2004.
19. Aldred MA, Ginn-Pease ME, Morrison CD, Popkie AP, Gimm O, Hoang-Vu C, Krause U, Dralle H, Jhiang SM, Plass C and Eng C: Caveolin-1 and caveolin-2, together with three bone morphogenetic protein-related genes, may encode novel tumor suppressors down-regulated in sporadic follicular thyroid carcinogenesis. Cancer Res 63:2864-2871, 2003.
20. Eble JN, Sauter G, Epstein JI and Sesterhenn IA, editors. World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Urinary system and Male Genital Organs. IARC Publishing, Lyon, pp. 281-290, 2004.
21. Epstein JI, Allsbrook WC Jr, Amin MB and Egevad LL; ISUP Grading Committee: The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. Am J Surg Pathol 29:1228-1242, 2005.
22. Tahir SA, Ren CZ, Timme TL, Gdor Y, Hoogeveen R, Morrisett JD, Frolov A, Ayala G, Wheeler TM and Thompson TC: Development of an immunoassay for serum caveolin-1: A novel biomarker for prostate cancer. Clin Cancer Res 9:3653-3659, 2003.
23. Nasu Y, Timme TL, Yang G, Bangma CH, Li L, Ren C, Park SH, De Leon M, Wang J and Thompson TC: Suppression of caveolin expression induces androgen sensitivity in metastatic androgeninsensitive mouse prostate cancer cells. Nat Med 4:1062-1064, 1998.
24. Bennett NC, Hooper JD, Johnson DW and Gobe GC: Expression profiles and functional associations of endogenous androgen receptor and caveolin-1 in prostate cancer cell lines. Prostate 74(5):478-487, 2014.
25. Yang G, Truong LD, Wheeler TM and Thompson TC: Caveolin-1 expression in clinically confined human prostate cancer: A novel prognostic marker. Cancer Res 59:5719-5723, 1999.
26. Li L, Ren C, Yang G, Goltsov AA, Tabata K and Thompson TC: Caveolin-1 promotes autoregulatory, AKT-mediated induction of cancer-promoting growth factors in prostate cancer cells. Mol Cancer Res 7:1781-1791, 2009.
27. Lee SW, Reimer CL, Oh P, Campbell DB and Schnitzer JE: Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells. Oncogene 16:1391-1397, 1998.
28. Rajjayabun PH, Garg S, Durkan GC, Charlton R, Robinson MC and Mellon JK: Caveolin-1 expression is associated with highgrade bladder cancer. Urology 58:811-814, 2001.
29. Pucci M, Bravatà V, Forte GI, Cammarata FP, Messa C, Gilardi MC and Minafra L: Caveolin-1, Breast cancer and ionizing radiation. Cancer Genomics Proteomics 12(3):143-152, 2015.
30. Wiechen K, Sers C, Agoulnik A, Arlt K, Dietel M, Schlag PM and Schneider U: Down-regulation of caveolin-1, a candidate tumorsuppressor gene, in sarcomas. Am J Pathol 158:833-839, 2001.
31. Wi Chen D and Che G: Value of caveolin-1 in cancer progression and prognosis: Emphasis on cancer-associated fibroblasts, human cancer cells and mechanism of caveolin-1 expression. Oncol Lett 8(4):1409-1421, 2014.
32. Thompson TC, Tahir SA, Li L, Watanabe M, Naruishi K, Yang G, Kadmon D, Logothetis CJ, Troncoso P, Ren C, Goltsov A and Park S: The role of caveolin-1 in prostate cancer: clinical implications. Prostate Cancer Prostatic Dis 13(1):6-11, 2010.
33. Sawada S, Ishikawa C, Tanji H, Nakachi S, Senba M, Okudaira T, Uchihara JN, Taira N, Ohshiro K, Yamada Y, Tanaka Y, Uezato H, Ohshima K, Sasai K, Burgering BM, Duc Dodon M, Fujii M, Sunakawa H and Mori N: Overexpression of caveolin-1 in adult T-cell leukemia. Blood 115:2220-2230, 2010.
34. Li L, Ren CH, Tahir SA, Ren C and Thompson TC: Caveolin-1 maintains activated AKT in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A. Mol Cell Biol 23:9389-9404, 2003.
35. Li L, Yang G, Ebara S, Satoh T, Nasu Y, Timme TL, Ren C, Wang J, Tahir SA and Thompson TC: Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells. Cancer Res 61:4386-4392, 2001.
36. Tahir SA, Yang G, Ebara S, Timme TL, Satoh T, Li L, Goltsov A, Ittmann M, Morrisett JD and Thompson TC: Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer. Cancer Res 61:3882-3885, 2001.
37. Goetz JG, Lajoie P, Wiseman SM and Nabi IR: Caveolin-1 in tumor progression: the good, the bad and the ugly. Cancer Metastasis Rev 27:715-735, 2008.
38. Savage K, Lambros MB, Robertson D, Jones RL, Jones C, Mackay A, James M, Hornick JL, Pereira EM, Milanezi F, Fletcher CD, Schmitt FC, Ashworth A and Reis-Filho JS: Caveolin 1 is overexpressed and amplified in a subset of basallike and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. Clin Cancer Res 13:90-101, 2007.
39. Abulrob A, Giuseppin S, Andrade MF, McDermid A, Moreno M and Stanimirovic D: Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveloae. Oncogene 23:6967-6979, 2004.
40. Fong A, Garcia E, Gwynn L, Lisanti MP, Fazzari MJ and Li M: Expression of caveolin-1 and caveolin-2 in urothelial carcinoma of the urinary bladder correlates with tumor grade and squamous differentiation. Am J Clin Pathol 120:93-100, 2003.
41. Watanabe M, Yang G, Cao GW, Tahir SA, Naruishi K, Tabata K, Fattah EA, Rajagopalan K, Timme TL, Park S, Kurosaka S, Edamura K, Tanimoto R, Demayo FJ, Goltsov AA and Thompson TC: Functional analysis of secreted caveolin-1 in mouse models of prostate cancer progression. Mol Cancer Res 7:1446-1455, 2009.
42. Yang G, Truong LD, Timme TL, Ren C, Wheeler TM, Park SH, Nasu Y, Bangma CH, Kattan MW, Scardino PT and Thompson TC: Elevated expression of caveolin is associated with prostate and breast cancer. Clin Cancer Res 4:1873-1880, 1998.
43. Thompson TC, Timme TL, Li L and Goltsov A: Caveolin-1, a metastasis-related gene that promotes cell survival in prostate cancer. Apoptosis 4:233-237, 1999.
44. Mouraviev V, Li LK, Tahir SA, Yang G, Timme TM, Goltsov A, Ren C, Satoh T, Wheeler TM, Ittmann MM, Miles BJ, Amato RJ, Kadmon D and Thompson TC: The role of caveolin-1 in androgen-insensitive prostate cancer. J Urol 168:1589-1596, 2002.