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Volumn 23, Issue 11, 2015, Pages 1748-1758

miR-221/222 are involved in response to sunitinib treatment in metastatic renal cell carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA; MICRORNA 221; MICRORNA 222; SUNITINIB; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; ANGIOGENESIS INHIBITOR; INDOLE DERIVATIVE; MIRN221 MICRORNA, HUMAN; MIRN222 MICRORNA, HUMAN; MTOR PROTEIN, HUMAN; PHARMACOLOGICAL BIOMARKER; PYRROLE DERIVATIVE; TARGET OF RAPAMYCIN KINASE; VASCULOTROPIN A;

EID: 84948710661     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2015.129     Document Type: Article
Times cited : (72)

References (55)
  • 2
    • 84899711381 scopus 로고    scopus 로고
    • Overall survival in renal-cell carcinoma with pazopanib versus sunitinib
    • Motzer RJ, Hutson TE, McCann L, Deen K, and Choueiri TK (2014). Overall survival in renal-cell carcinoma with pazopanib versus sunitinib. N Engl J Med 370: 1769-1770.
    • (2014) N Engl J Med , vol.370 , pp. 1769-1770
    • Motzer, R.J.1    Hutson, T.E.2    McCann, L.3    Deen, K.4    Choueiri, T.K.5
  • 3
    • 84891713447 scopus 로고    scopus 로고
    • Tivozanib versus sorafenib as initial targeted therapy for patients with metastatic renal cell carcinoma: Results from a phase III trial
    • Motzer RJ, Nosov D, Eisen T, Bondarenko I, Lesovoy V, Lipatov O, et al. (2013). Tivozanib versus sorafenib as initial targeted therapy for patients with metastatic renal cell carcinoma: results from a phase III trial. J Clin Oncol 31: 3791-3799.
    • (2013) J Clin Oncol , vol.31 , pp. 3791-3799
    • Motzer, R.J.1    Nosov, D.2    Eisen, T.3    Bondarenko, I.4    Lesovoy, V.5    Lipatov, O.6
  • 4
    • 68949145218 scopus 로고    scopus 로고
    • Overall survival, and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
    • Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Oudard S, et al. (2009). Overall survival, and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol 27: 3584-3590.
    • (2009) J Clin Oncol , vol.27 , pp. 3584-3590
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3    Michaelson, M.D.4    Bukowski, R.M.5    Oudard, S.6
  • 5
    • 83255162010 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF), VEGF receptors, and their inhibitors for antiangiogenic tumor therapy
    • Takahashi S (2011). Vascular endothelial growth factor (VEGF), VEGF receptors, and their inhibitors for antiangiogenic tumor therapy. Biol Pharm Bull 34: 1785-1788.
    • (2011) Biol Pharm Bull , vol.34 , pp. 1785-1788
    • Takahashi, S.1
  • 7
    • 84861735450 scopus 로고    scopus 로고
    • Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: Clinical characteristics, risk factors, and subsequent therapy
    • Heng DY, Mackenzie MJ, Vaishampayan UN, Bjarnason GA, Knox JJ, Tan MH, et al. (2012). Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy. Ann Oncol 23: 1549-1555.
    • (2012) Ann Oncol , vol.23 , pp. 1549-1555
    • Heng, D.Y.1    Mackenzie, M.J.2    Vaishampayan, U.N.3    Bjarnason, G.A.4    Knox, J.J.5    Tan, M.H.6
  • 8
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-Angiogenic therapy
    • Bergers G, and Hanahan D (2008). Modes of resistance to anti-Angiogenic therapy. Nat Rev Cancer 8: 592-603.
    • (2008) Nat Rev Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 9
    • 77953467629 scopus 로고    scopus 로고
    • Reversible epithelial to mesenchymal transition, and acquired resistance to sunitinib in patients with renal cell carcinoma: Evidence from a xenograft study
    • Hammers HJ, Verheul HM, Salumbides B, Sharma R, Rudek M, Jaspers J, et al. (2010). Reversible epithelial to mesenchymal transition, and acquired resistance to sunitinib in patients with renal cell carcinoma: evidence from a xenograft study. Mol Cancer Ther 9: 1525-1535.
    • (2010) Mol Cancer Ther , vol.9 , pp. 1525-1535
    • Hammers, H.J.1    Verheul, H.M.2    Salumbides, B.3    Sharma, R.4    Rudek, M.5    Jaspers, J.6
  • 10
    • 84877855147 scopus 로고    scopus 로고
    • Inhibition of histone demethylase JMJD1A improves anti-Angiogenic therapy, and reduces tumor-Associated macrophages
    • Osawa T, Tsuchida R, Muramatsu M, Shimamura T, Wang F, Suehiro J, et al. (2013). Inhibition of histone demethylase JMJD1A improves anti-Angiogenic therapy, and reduces tumor-Associated macrophages. Cancer Res 73: 3019-3028.
    • (2013) Cancer Res , vol.73 , pp. 3019-3028
    • Osawa, T.1    Tsuchida, R.2    Muramatsu, M.3    Shimamura, T.4    Wang, F.5    Suehiro, J.6
  • 13
    • 70350755290 scopus 로고    scopus 로고
    • MicroRNA profiling of clear cell renal cell cancer identifies a robust signature to define renal malignancy
    • Jung M, Mollenkopf HJ, Grimm C, Wagner I, Albrecht M, Waller T, et al. (2009). MicroRNA profiling of clear cell renal cell cancer identifies a robust signature to define renal malignancy. J Cell Mol Med 13(9B): 3918-3928.
    • (2009) J Cell Mol Med , vol.13 , Issue.9 , pp. 3918-3928
    • Jung, M.1    Mollenkopf, H.J.2    Grimm, C.3    Wagner, I.4    Albrecht, M.5    Waller, T.6
  • 14
    • 80051551689 scopus 로고    scopus 로고
    • MiRNA profiling for clear cell renal cell carcinoma: Biomarker discovery, and identification of potential controls, and consequences of miRNA dysregulation
    • White NM, Bao TT, Grigull J, Youssef YM, Girgis A, Diamandis M, et al. (2011). miRNA profiling for clear cell renal cell carcinoma: biomarker discovery, and identification of potential controls, and consequences of miRNA dysregulation. J Urol 186: 1077-1083.
    • (2011) J Urol , vol.186 , pp. 1077-1083
    • White, N.M.1    Bao, T.T.2    Grigull, J.3    Youssef, Y.M.4    Girgis, A.5    Diamandis, M.6
  • 15
    • 84901044361 scopus 로고    scopus 로고
    • MiR-141 is a key regulator of renal cell carcinoma proliferation, and metastasis by controlling EphA2 expression
    • Chen X, Wang X, Ruan A, Han W, Zhao Y, Lu X, et al. (2014). miR-141 is a key regulator of renal cell carcinoma proliferation, and metastasis by controlling EphA2 expression. Clin Cancer Res 20: 2617-2630.
    • (2014) Clin Cancer Res , vol.20 , pp. 2617-2630
    • Chen, X.1    Wang, X.2    Ruan, A.3    Han, W.4    Zhao, Y.5    Lu, X.6
  • 16
    • 73749083718 scopus 로고    scopus 로고
    • The miR-17-92 cluster is over expressed in, and has an oncogenic effect on renal cell carcinoma
    • Chow TF, Mankaruos M, Scorilas A, Youssef Y, Girgis A, Mossad S, et al. (2010). The miR-17-92 cluster is over expressed in, and has an oncogenic effect on renal cell carcinoma. J Urol 183: 743-751.
    • (2010) J Urol , vol.183 , pp. 743-751
    • Chow, T.F.1    Mankaruos, M.2    Scorilas, A.3    Youssef, Y.4    Girgis, A.5    Mossad, S.6
  • 17
    • 84883651195 scopus 로고    scopus 로고
    • MiR-192, miR-194, and miR-215: A convergent microRNA network suppressing tumor progression in renal cell carcinoma
    • Khella HW, Bakhet M, Allo G, Jewett MA, Girgis AH, Latif A, et al. (2013). miR-192, miR-194, and miR-215: a convergent microRNA network suppressing tumor progression in renal cell carcinoma. Carcinogenesis 34: 2231-2239.
    • (2013) Carcinogenesis , vol.34 , pp. 2231-2239
    • Khella, H.W.1    Bakhet, M.2    Allo, G.3    Jewett, M.A.4    Girgis, A.H.5    Latif, A.6
  • 18
    • 84859015588 scopus 로고    scopus 로고
    • Pleiotropic action of renal cell carcinoma-dysregulated miRNAs on hypoxia-related signaling pathways
    • Lichner Z, Mejia-Guerrero S, Ignacak M, Krizova A, Bao TT, Girgis AH, et al. (2012). Pleiotropic action of renal cell carcinoma-dysregulated miRNAs on hypoxia-related signaling pathways. Am J Pathol 180: 1675-1687.
    • (2012) Am J Pathol , vol.180 , pp. 1675-1687
    • Lichner, Z.1    Mejia-Guerrero, S.2    Ignacak, M.3    Krizova, A.4    Bao, T.T.5    Girgis, A.H.6
  • 19
    • 84896726090 scopus 로고    scopus 로고
    • MicroRNAs with prognostic potential for metastasis in clear cell renal cell carcinoma: A comparison of primary tumors, and distant metastases
    • Heinzelmann J, Unrein A, Wickmann U, Baumgart S, Stapf M, Szendroi A, et al. (2014). MicroRNAs with prognostic potential for metastasis in clear cell renal cell carcinoma: a comparison of primary tumors, and distant metastases. Ann Surg Oncol 21: 1046-1054.
    • (2014) Ann Surg Oncol , vol.21 , pp. 1046-1054
    • Heinzelmann, J.1    Unrein, A.2    Wickmann, U.3    Baumgart, S.4    Stapf, M.5    Szendroi, A.6
  • 20
    • 81955164748 scopus 로고    scopus 로고
    • MiRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215
    • White NM, Khella HW, Grigull J, Adzovic S, Youssef YM, Honey RJ, et al. (2011). miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215. Br J Cancer 105: 1741-1749.
    • (2011) Br J Cancer , vol.105 , pp. 1741-1749
    • White, N.M.1    Khella, H.W.2    Grigull, J.3    Adzovic, S.4    Youssef, Y.M.5    Honey, R.J.6
  • 21
    • 77956809127 scopus 로고    scopus 로고
    • Accurate molecular classification of renal tumors using microRNA expression
    • Fridman E, Dotan Z, Barshack I, David MB, Dov A, Tabak S, et al. (2010). Accurate molecular classification of renal tumors using microRNA expression. J Mol Diagn 12: 687-696.
    • (2010) J Mol Diagn , vol.12 , pp. 687-696
    • Fridman, E.1    Dotan, Z.2    Barshack, I.3    David, M.B.4    Dov, A.5    Tabak, S.6
  • 22
    • 79953234117 scopus 로고    scopus 로고
    • Accurate molecular classification of kidney cancer subtypes using microRNA signature
    • Youssef YM, White NM, Grigull J, Krizova A, Samy C, Mejia-Guerrero S, et al. (2011). Accurate molecular classification of kidney cancer subtypes using microRNA signature. Eur Urol 59: 721-730.
    • (2011) Eur Urol , vol.59 , pp. 721-730
    • Youssef, Y.M.1    White, N.M.2    Grigull, J.3    Krizova, A.4    Samy, C.5    Mejia-Guerrero, S.6
  • 24
    • 79959298372 scopus 로고    scopus 로고
    • Identification of plasma microRNA-21 as a biomarker for early detection, and chemosensitivity of non-small cell lung cancer
    • Wei J, Gao W, Zhu CJ, Liu YQ, Mei Z, Cheng T, et al. (2011). Identification of plasma microRNA-21 as a biomarker for early detection, and chemosensitivity of non-small cell lung cancer. Chin J Cancer 30: 407-414.
    • (2011) Chin J Cancer , vol.30 , pp. 407-414
    • Wei, J.1    Gao, W.2    Zhu, C.J.3    Liu, Y.Q.4    Mei, Z.5    Cheng, T.6
  • 25
    • 84867048400 scopus 로고    scopus 로고
    • The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer
    • Takahashi M, Cuatrecasas M, Balaguer F, Hur K, Toiyama Y, Castells A, et al. (2012). The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer. PLoS One 7: e46684.
    • (2012) PLoS One , vol.7 , pp. e46684
    • Takahashi, M.1    Cuatrecasas, M.2    Balaguer, F.3    Hur, K.4    Toiyama, Y.5    Castells, A.6
  • 26
    • 84873120034 scopus 로고    scopus 로고
    • MiR-342 is associated with estrogen receptor-?expression, and response to tamoxifen in breast cancer
    • He YJ Wu JZ Ji MH, Ma T, Qiao EQ, Ma R, et al. (2013). miR-342 is associated with estrogen receptor-?expression, and response to tamoxifen in breast cancer. Exp Ther Med 5: 813-818.
    • (2013) Exp Ther Med , vol.5 , pp. 813-818
    • He, Y.J.1    Wu, J.Z.2    Ji, M.H.3    Ma, T.4    Qiao, E.Q.5    Ma, R.6
  • 27
    • 76249126867 scopus 로고    scopus 로고
    • Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma
    • Huang D, Ding Y, Li Y, Luo WM, Zhang ZF, Snider J, et al. (2010). Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma. Cancer Res 70: 1053-1062.
    • (2010) Cancer Res , vol.70 , pp. 1053-1062
    • Huang, D.1    Ding, Y.2    Li, Y.3    Luo, W.M.4    Zhang, Z.F.5    Snider, J.6
  • 28
    • 84898801084 scopus 로고    scopus 로고
    • Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis
    • Korn C, Scholz B, Hu J, Srivastava K, Wojtarowicz J, Arnsperger T, et al. (2014). Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis. Development 141: 1757-1766.
    • (2014) Development , vol.141 , pp. 1757-1766
    • Korn, C.1    Scholz, B.2    Hu, J.3    Srivastava, K.4    Wojtarowicz, J.5    Arnsperger, T.6
  • 29
    • 79959553858 scopus 로고    scopus 로고
    • Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells
    • Stefater, JA 3rd, Lewkowich I, Rao S, Mariggi G, Carpenter AC, Burr AR, et al. (2011). Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature 474: 511-515.
    • (2011) Nature , vol.474 , pp. 511-515
    • Stefater, J.A.1    Lewkowich, I.2    Rao, S.3    Mariggi, G.4    Carpenter, A.C.5    Burr, A.R.6
  • 30
    • 34247554263 scopus 로고    scopus 로고
    • Dicer dependent microRNAs regulate gene expression, and functions in human endothelial cells
    • Suárez Y, Fernández-Hernando C, Pober JS, and Sessa WC (2007). Dicer dependent microRNAs regulate gene expression, and functions in human endothelial cells. Circ Res 100: 1164-1173.
    • (2007) Circ Res , vol.100 , pp. 1164-1173
    • Suárez, Y.1    Fernández-Hernando, C.2    Pober, J.S.3    Sessa, W.C.4
  • 31
    • 84906669898 scopus 로고    scopus 로고
    • Current management, and future perspectives of metastatic renal cell carcinoma
    • Lee-Ying R, Lester R, and Heng D (2014). Current management, and future perspectives of metastatic renal cell carcinoma. Int J Urol 21: 847-855.
    • (2014) Int J Urol , vol.21 , pp. 847-855
    • Lee-Ying, R.1    Lester, R.2    Heng, D.3
  • 32
    • 34547108341 scopus 로고    scopus 로고
    • Clinical factors associated with outcome in patients with metastatic clear-cell renal cell carcinoma treated with vascular endothelial growth factor-Dargeted therapy
    • Choueiri TK, Garcia JA, Elson P, Khasawneh M, Usman S, Golshayan AR, et al. (2007). Clinical factors associated with outcome in patients with metastatic clear-cell renal cell carcinoma treated with vascular endothelial growth factor-Dargeted therapy. Cancer 110: 543-550.
    • (2007) Cancer , vol.110 , pp. 543-550
    • Choueiri, T.K.1    Garcia, J.A.2    Elson, P.3    Khasawneh, M.4    Usman, S.5    Golshayan, A.R.6
  • 33
    • 73349084973 scopus 로고    scopus 로고
    • Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-Dargeted agents: Results from a large, multicenter study
    • Heng DY, Xie W, Regan MM, Warren MA, Golshayan AR, Sahi C, et al. (2009). Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-Dargeted agents: results from a large, multicenter study. J Clin Oncol 27: 5794-5799.
    • (2009) J Clin Oncol , vol.27 , pp. 5794-5799
    • Heng, D.Y.1    Xie, W.2    Regan, M.M.3    Warren, M.A.4    Golshayan, A.R.5    Sahi, C.6
  • 34
    • 54049095545 scopus 로고    scopus 로고
    • Prognostic nomogram for sunitinib in patients with metastatic renal cell carcinoma
    • Motzer RJ, Bukowski RM, Figlin RA, Hutson TE, Michaelson MD, Kim ST, et al. (2008). Prognostic nomogram for sunitinib in patients with metastatic renal cell carcinoma. Cancer 113: 1552-1558.
    • (2008) Cancer , vol.113 , pp. 1552-1558
    • Motzer, R.J.1    Bukowski, R.M.2    Figlin, R.A.3    Hutson, T.E.4    Michaelson, M.D.5    Kim, S.T.6
  • 35
    • 84903219970 scopus 로고    scopus 로고
    • Sarcomatoid features, necrosis, and grade are prognostic factors in metastatic clear cell renal cell carcinoma with vascular endothelial growth factor-Dargeted therapy
    • Park JY, Lee JL, Baek S Eo SH, Go H Ro JY, et al. (2014). Sarcomatoid features, necrosis, and grade are prognostic factors in metastatic clear cell renal cell carcinoma with vascular endothelial growth factor-Dargeted therapy. Hum Pathol 45: 1437-1444.
    • (2014) Hum Pathol , vol.45 , pp. 1437-1444
    • Park, J.Y.1    Lee, J.L.2    Baek, S.3    Eo, S.H.4    Go, H.5    Ro, J.Y.6
  • 36
    • 84898478153 scopus 로고    scopus 로고
    • Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma
    • Prior C, Perez-Gracia JL, Garcia-Donas J, Rodriguez-Antona C, Guruceaga E, Esteban E, et al. (2014). Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma. PLoS One 9: e86263.
    • (2014) PLoS One , vol.9 , pp. e86263
    • Prior, C.1    Perez-Gracia, J.L.2    Garcia-Donas, J.3    Rodriguez-Antona, C.4    Guruceaga, E.5    Esteban, E.6
  • 37
    • 84876288448 scopus 로고    scopus 로고
    • A possible role for microRNA-141 down-regulation in sunitinib resistant metastatic clear cell renal cell carcinoma through induction of epithelial-Domesenchymal transition, and hypoxia resistance
    • Berkers J, Govaere O, Wolter P, Beuselinck B, Schöffski P, van Kempen LC, et al. (2013). A possible role for microRNA-141 down-regulation in sunitinib resistant metastatic clear cell renal cell carcinoma through induction of epithelial-Domesenchymal transition, and hypoxia resistance. J Urol 189: 1930-1938.
    • (2013) J Urol , vol.189 , pp. 1930-1938
    • Berkers, J.1    Govaere, O.2    Wolter, P.3    Beuselinck, B.4    Schöffski, P.5    Van Kempen, L.C.6
  • 38
    • 84871530565 scopus 로고    scopus 로고
    • MicroRNA expression profiling of peripheral blood samples predicts resistance to first-line sunitinib in advanced renal cell carcinoma patients
    • Gámez-Pozo A, Anton-Aparicio LM, Bayona C, Borrega P, Gallegos Sancho MI, García-Domínguez R, et al. (2012). MicroRNA expression profiling of peripheral blood samples predicts resistance to first-line sunitinib in advanced renal cell carcinoma patients. Neoplasia 14: 1144-1152.
    • (2012) Neoplasia , vol.14 , pp. 1144-1152
    • Gámez-Pozo, A.1    Anton-Aparicio, L.M.2    Bayona, C.3    Borrega, P.4    Gallegos Sancho, M.I.5    García-Domínguez, R.6
  • 40
    • 84902960997 scopus 로고    scopus 로고
    • Higher circulating expression levels of miR-221 associated with poor overall survival in renal cell carcinoma patients
    • Teixeira AL, Ferreira M, Silva J, Gomes M, Dias F, Santos JI, et al. (2014). Higher circulating expression levels of miR-221 associated with poor overall survival in renal cell carcinoma patients. Tumour Biol 35: 4057-4066.
    • (2014) Tumour Biol , vol.35 , pp. 4057-4066
    • Teixeira, A.L.1    Ferreira, M.2    Silva, J.3    Gomes, M.4    Dias, F.5    Santos, J.I.6
  • 41
    • 84872182721 scopus 로고    scopus 로고
    • Increased miR-221 expression in hepatocellular carcinoma tissues, and its role in enhancing cell growth, and inhibiting apoptosis in vitro
    • Rong M, Chen G, and Dang Y (2013). Increased miR-221 expression in hepatocellular carcinoma tissues, and its role in enhancing cell growth, and inhibiting apoptosis in vitro. BMC Cancer 13: 21.
    • (2013) BMC Cancer , vol.13 , pp. 21
    • Rong, M.1    Chen, G.2    Dang, Y.3
  • 42
    • 84973530978 scopus 로고    scopus 로고
    • MiR-221 affects multiple cancer pathways by modulating the level of hundreds messenger RNAs
    • Lupini L, Bassi C, Ferracin M, Bartonicek, N, D'Abundo L, Zagatti B, et al. (2013). miR-221 affects multiple cancer pathways by modulating the level of hundreds messenger RNAs. Front Genet 4: 64.
    • (2013) Front Genet , vol.4 , pp. 64
    • Lupini, L.1    Bassi, C.2    Ferracin, M.3    Bartonicek, N.4    D'Abundo, L.5    Zagatti, B.6
  • 43
    • 84881502569 scopus 로고    scopus 로고
    • MicroRNA-221 mediates the effects of PDGF-BB on migration, proliferation, and the epithelial-mesenchymal transition in pancreatic cancer cells
    • Su A, He S, Tian B, Hu W, and Zhang Z (2013). MicroRNA-221 mediates the effects of PDGF-BB on migration, proliferation, and the epithelial-mesenchymal transition in pancreatic cancer cells. PLoS One 8: e71309.
    • (2013) PLoS One , vol.8 , pp. e71309
    • Su, A.1    He, S.2    Tian, B.3    Hu, W.4    Zhang, Z.5
  • 44
    • 77955429106 scopus 로고    scopus 로고
    • MicroRNA-221, and microRNA-222 regulate gastric carcinoma cell proliferation, and radioresistance by targeting PTEN
    • Chun-Zhi Z, Lei H, An-Ling Z, Yan-Chao F, Xiao Y, Guang-Xiu W, et al. (2010). MicroRNA-221, and microRNA-222 regulate gastric carcinoma cell proliferation, and radioresistance by targeting PTEN. BMC Cancer 10: 367.
    • (2010) BMC Cancer , vol.10 , pp. 367
    • Chun-Zhi, Z.1    Lei, H.2    An-Ling, Z.3    Yan-Chao, F.4    Xiao, Y.5    Guang-Xiu, W.6
  • 45
    • 84878881786 scopus 로고    scopus 로고
    • MiR-221/222 targets adiponectin receptor 1 to promote the epithelial-Do-mesenchymal transition in breast cancer
    • Hwang MS, Yu N, Stinson SY, Yue P, Newman RJ, Allan BB, et al. (2013). miR-221/222 targets adiponectin receptor 1 to promote the epithelial-Do-mesenchymal transition in breast cancer. PLoS One 8: e66502.
    • (2013) PLoS One , vol.8 , pp. e66502
    • Hwang, M.S.1    Yu, N.2    Stinson, S.Y.3    Yue, P.4    Newman, R.J.5    Allan, B.B.6
  • 46
    • 84887840885 scopus 로고    scopus 로고
    • MiR-221/-222 differentiate prognostic groups in advanced breast cancers, and influence cell invasion
    • Falkenberg N, Anastasov N, Rappl K, Braselmann H, Auer G, Walch A, et al. (2013). MiR-221/-222 differentiate prognostic groups in advanced breast cancers, and influence cell invasion. Br J Cancer 109: 2714-2723.
    • (2013) Br J Cancer , vol.109 , pp. 2714-2723
    • Falkenberg, N.1    Anastasov, N.2    Rappl, K.3    Braselmann, H.4    Auer, G.5    Walch, A.6
  • 47
    • 37549068984 scopus 로고    scopus 로고
    • Targeting microRNA expression to regulate angiogenesis
    • Kuehbacher A, Urbich C, and Dimmeler S (2008). Targeting microRNA expression to regulate angiogenesis. Trends Pharmacol Sci 29: 12-15.
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 12-15
    • Kuehbacher, A.1    Urbich, C.2    Dimmeler, S.3
  • 48
    • 84890182925 scopus 로고    scopus 로고
    • Resistance to tyrosine kinase inhibitors in clear cell renal cell carcinoma: From the patient's bed to molecular mechanisms
    • Buczek M, Escudier B, Bartnik E, Szczylik C, and Czarnecka A (2014). Resistance to tyrosine kinase inhibitors in clear cell renal cell carcinoma: from the patient's bed to molecular mechanisms. Biochim Biophys Acta 1845: 31-41.
    • (2014) Biochim Biophys Acta , vol.1845 , pp. 31-41
    • Buczek, M.1    Escudier, B.2    Bartnik, E.3    Szczylik, C.4    Czarnecka, A.5
  • 51
    • 52449100144 scopus 로고    scopus 로고
    • Role of microRNAs in vascular diseases, inflammation, and angiogenesis
    • Urbich C, Kuehbacher A, and Dimmeler S (2008). Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res 79: 581-588.
    • (2008) Cardiovasc Res , vol.79 , pp. 581-588
    • Urbich, C.1    Kuehbacher, A.2    Dimmeler, S.3
  • 52
    • 84884680394 scopus 로고    scopus 로고
    • Analyses of potential predictive markers, and survival data for a response to sunitinib in patients with metastatic renal cell carcinoma
    • Dornbusch J, Zacharis A, Meinhardt M, Erdmann K, Wolff I, Froehner M, et al. (2013). Analyses of potential predictive markers, and survival data for a response to sunitinib in patients with metastatic renal cell carcinoma. PLoS One 8: e76386.
    • (2013) PLoS One , vol.8 , pp. e76386
    • Dornbusch, J.1    Zacharis, A.2    Meinhardt, M.3    Erdmann, K.4    Wolff, I.5    Froehner, M.6
  • 53
    • 84876739783 scopus 로고    scopus 로고
    • Expression level of vascular endothelial growth factor receptor-2 in radical nephrectomy specimens as a prognostic predictor in patients with metastatic renal cell carcinoma treated with sunitinib
    • Terakawa T, Miyake H, Kusuda Y, and Fujisawa M (2013). Expression level of vascular endothelial growth factor receptor-2 in radical nephrectomy specimens as a prognostic predictor in patients with metastatic renal cell carcinoma treated with sunitinib. Urol Oncol 31: 493-498.
    • (2013) Urol Oncol , vol.31 , pp. 493-498
    • Terakawa, T.1    Miyake, H.2    Kusuda, Y.3    Fujisawa, M.4
  • 54
    • 82855175161 scopus 로고    scopus 로고
    • Molecular imaging of a cancer-Dargeting theragnostics probe using a nucleolin aptamer-, and microRNA-221 molecular beacon-conjugated nanoparticle
    • Kim JK, Choi KJ, Lee M Jo MH, and Kim S (2012). Molecular imaging of a cancer-Dargeting theragnostics probe using a nucleolin aptamer-, and microRNA-221 molecular beacon-conjugated nanoparticle. Biomaterials 33: 207-217.
    • (2012) Biomaterials , vol.33 , pp. 207-217
    • Kim, J.K.1    Choi, K.J.2    Lee Jo M, M.H.3    Kim, S.4
  • 55
    • 77951484580 scopus 로고    scopus 로고
    • Dysregulation of kallikrein-related peptidases in renal cell carcinoma: Potential targets of miRNAs
    • White NM, Bui A, Mejia-Guerrero S, Chao J, Soosaipillai A, Youssef Y, et al. (2010). Dysregulation of kallikrein-related peptidases in renal cell carcinoma: potential targets of miRNAs. Biol Chem 391: 411-423.
    • (2010) Biol Chem , vol.391 , pp. 411-423
    • White, N.M.1    Bui, A.2    Mejia-Guerrero, S.3    Chao, J.4    Soosaipillai, A.5    Youssef, Y.6


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