Inhibition of pathogenic mutant SOD1 aggregation in cultured motor neuronal cells by prevention of its SUMOylation on lysine 75

Neurodegenerative Diseases

Volumn 16, Issue 3-4, 2016, Pages 161-171

  Dangoumau, Audrey ^a   Marouillat, Sylviane ^a   Burlaud Gaillard, Julien ^a   Uzbekov, Rustem ^a   Veyrat Durebex, Charlotte ^a   Blasco, Hélène ^a,b   Arnoult, Christophe ^a   Corcia, Philippe ^a,c   Andres, Christian R ^a,b   Vourc'h, Patrick ^a,b  

^a UNIVERSITÉ DE TOURS   (France)

^b UNIVERSITY HOSPITAL OF TOURS   (France)

^c CHU BRETONNEAU   (France)

Author keywords

Amyotrophic lateral sclerosis; Motor neurons; Small ubiquitin modifier 1; Superoxide dismutase 1

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; LYSINE; SUMO 1 PROTEIN; GREEN FLUORESCENT PROTEIN; SOD1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; CORRELATIVE LIGHT AND ELECTRON MICROSCOPY; CYTOSOL; ELECTRON MICROSCOPY; ENZYME INHIBITION; FLUORESCENCE; GENETIC TRANSFECTION; IMMUNOCYTOCHEMISTRY; MOTONEURON; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; SUMOYLATION; ANIMAL; CELL LINE; CELL SURVIVAL; CHO CELL LINE; CRICETULUS; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOUSE; MUTATION; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEINOSIS; ULTRASTRUCTURE;

ANIMALS; CELL LINE; CELL SURVIVAL; CHO CELLS; CRICETULUS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; LYSINE; MICE; MOTOR NEURONS; MUTATION; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEIN STRUCTURE, SECONDARY; SUMO-1 PROTEIN; SUMOYLATION; SUPEROXIDE DISMUTASE-1;

EID: 84948701265     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000439254     Document Type: Article

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