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Volumn 14, Issue 12, 2015, Pages 3258-3273

The extracellular vesicles of the helminth pathogen, Fasciola hepatica: Biogenesis pathways and cargo molecules involved in parasite pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE; CARBOXYPEPTIDASE C; CATHEPSIN; CATHEPSIN B; CATHEPSIN L; CATHEPSIN X; CYTOSOL AMINOPEPTIDASE; ENOLASE; ENZYME PRECURSOR; FATTY ACID BINDING PROTEIN; MALATE DEHYDROGENASE; METALLOPROTEINASE; PEROXIREDOXIN; PROPIONYL COENZYME A CARBOXYLASE; SIGNAL PEPTIDE; THIOREDOXIN; TRYPSIN; HELMINTH PROTEIN;

EID: 84948666568     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M115.053934     Document Type: Article
Times cited : (186)

References (75)
  • 1
    • 25844451175 scopus 로고    scopus 로고
    • Fascioliasis and other plant-borne trematode zoonoses
    • Mas-Coma, S., Bargues, M. D., and Valero, M. A. (2005) Fascioliasis and other plant-borne trematode zoonoses. Int. J. Parasitol. 35, 1255-1278
    • (2005) Int. J. Parasitol. , vol.35 , pp. 1255-1278
    • Mas-Coma, S.1    Bargues, M.D.2    Valero, M.A.3
  • 4
    • 0002789914 scopus 로고    scopus 로고
    • Development of Fasciola hepatica in the mammalian host
    • (Dalton, J.P., ed). CABI, Oxford, United Kingdom
    • Fairweather, I, Threadgold, L. T., and Hanna, R. E. B. (1999) Development of Fasciola hepatica in the mammalian host. In Fasciolosis (Dalton, J.P., ed) pp 1-29, CABI, Oxford, United Kingdom
    • (1999) Fasciolosis , pp. 1-29
    • Fairweather, I.1    Threadgold, L.T.2    Hanna, R.E.B.3
  • 5
    • 2342442531 scopus 로고    scopus 로고
    • Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: Propeptide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells
    • Collins, P. R., Stack, C. M., O'Neill, S. M., Doyle, S., Ryan, T., Brennan, G. P., Mousley, A., Stewart, M., Maule, A. G., Dalton, J. P., and Donnelly, S. (2004) Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propeptide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells. J. Biol. Chem. 279, 17038-17046
    • (2004) J. Biol. Chem. , vol.279 , pp. 17038-17046
    • Collins, P.R.1    Stack, C.M.2    O'Neill, S.M.3    Doyle, S.4    Ryan, T.5    Brennan, G.P.6    Mousley, A.7    Stewart, M.8    Maule, A.G.9    Dalton, J.P.10    Donnelly, S.11
  • 8
    • 34347400573 scopus 로고    scopus 로고
    • Comparative proteomics of excretory-secretory proteins released by the liver fluke Fasciola hepatica in sheep host bile and during in vitro culture ex host
    • Morphew, R. M., Wright, H. A., La Course, E. J., Woods, D. J., and Brophy, P. M. (2007) Comparative proteomics of excretory-secretory proteins released by the liver fluke Fasciola hepatica in sheep host bile and during in vitro culture ex host. Mol. Cell. Proteomics 6, 963-972
    • (2007) Mol. Cell. Proteomics , vol.6 , pp. 963-972
    • Morphew, R.M.1    Wright, H.A.2    La Course, E.J.3    Woods, D.J.4    Brophy, P.M.5
  • 9
    • 46749110826 scopus 로고    scopus 로고
    • Proteomic and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen, Fasciola hepatica: Expansion of a repertoire of virulence-associated factors
    • Robinson, M. W., Tort, J. F., Wong, E., Donnelly, S. M., Lowther, J., Xu, W., Stack, C. M., Padula, M., Herbert, B., and Dalton, J. P. (2008) Proteomic and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen, Fasciola hepatica: expansion of a repertoire of virulence-associated factors. Mol. Cell. Proteomics 7, 1111-1123
    • (2008) Mol. Cell. Proteomics , vol.7 , pp. 1111-1123
    • Robinson, M.W.1    Tort, J.F.2    Wong, E.3    Donnelly, S.M.4    Lowther, J.5    Xu, W.6    Stack, C.M.7    Padula, M.8    Herbert, B.9    Dalton, J.P.10
  • 10
    • 68649087906 scopus 로고    scopus 로고
    • An integrated transcriptomic and proteomic analysis of the secretome of the helminth pathogen, Fasciola hepatica: Proteins associated with invasion and infection of the mammalian host
    • Robinson, M. W., Menon, R., Donnelly, S. M., Dalton, J. P. And Ranganathan, S. (2009) An integrated transcriptomic and proteomic analysis of the secretome of the helminth pathogen, Fasciola hepatica: proteins associated with invasion and infection of the mammalian host. Mol. Cell. Proteomics 8, 1891-1907
    • (2009) Mol. Cell. Proteomics , vol.8 , pp. 1891-1907
    • Robinson, M.W.1    Menon, R.2    Donnelly, S.M.3    Dalton, J.P.4    Ranganathan, S.5
  • 11
    • 84937073781 scopus 로고    scopus 로고
    • The Fasciola hepatica genome: Gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution
    • Cwiklinski, K., Dalton, J. P., Dufresne, P. J., La Course, J., Williams, D. J., Hodgkinson, J., and Paterson, S. (2015) The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution. Genome Biol. 16, 71
    • (2015) Genome Biol. , vol.16 , pp. 71
    • Cwiklinski, K.1    Dalton, J.P.2    Dufresne, P.J.3    La Course, J.4    Williams, D.J.5    Hodgkinson, J.6    Paterson, S.7
  • 13
    • 84870248865 scopus 로고    scopus 로고
    • Exosomes: Cell garbage can, therapeutic carrier, or trojan horse?
    • Thébaud, B., and Stewart, D. J. (2012) Exosomes: cell garbage can, therapeutic carrier, or trojan horse? Circulation 126, 2553-2555
    • (2012) Circulation , vol.126 , pp. 2553-2555
    • Thébaud, B.1    Stewart, D.J.2
  • 15
    • 84886738545 scopus 로고    scopus 로고
    • Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies
    • Record, M., Carayon, K., Poirot, M., and Silvente-Poirot, S. (2014) Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies. Biochim. Biophys. Acta 1841, 108-120
    • (2014) Biochim. Biophys. Acta , vol.1841 , pp. 108-120
    • Record, M.1    Carayon, K.2    Poirot, M.3    Silvente-Poirot, S.4
  • 17
    • 79955571241 scopus 로고    scopus 로고
    • Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury
    • Gatti, S., Bruno, S., Deregibus, M. C., Sordi, A., Cantaluppi, V., Tetta, C., and Camussi, G. (2011) Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury. Nephrol. Dial. Transplant. 26, 1474-1483
    • (2011) Nephrol. Dial. Transplant. , vol.26 , pp. 1474-1483
    • Gatti, S.1    Bruno, S.2    Deregibus, M.C.3    Sordi, A.4    Cantaluppi, V.5    Tetta, C.6    Camussi, G.7
  • 18
    • 23944509766 scopus 로고    scopus 로고
    • Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation
    • Del Conde, I., Shrimpton, C. N., Thiagarajan, P., and López, J. A. (2005) Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood 106, 1604-1611
    • (2005) Blood , vol.106 , pp. 1604-1611
    • Del Conde, I.1    Shrimpton, C.N.2    Thiagarajan, P.3    López, J.A.4
  • 19
    • 84861228574 scopus 로고    scopus 로고
    • Extracellular vesicles - Vehicles that spread cancer genes
    • Rak, J., and Guha, A. (2012) Extracellular vesicles - vehicles that spread cancer genes. Bioessays. 34, 489-497
    • (2012) Bioessays. , vol.34 , pp. 489-497
    • Rak, J.1    Guha, A.2
  • 21
    • 84939973335 scopus 로고    scopus 로고
    • Exosome-like vesicles derived by Schistosoma japonicum adult worms mediates M1 type immune- activity of macrophage
    • Wang, L., Li, Z., Shen, J., Liu, Z., Liang, J., Wu, X., Sun, X., and Wu, Z. (2015) Exosome-like vesicles derived by Schistosoma japonicum adult worms mediates M1 type immune- activity of macrophage. Parasitol. Res. 114, 1865-1873
    • (2015) Parasitol. Res. , vol.114 , pp. 1865-1873
    • Wang, L.1    Li, Z.2    Shen, J.3    Liu, Z.4    Liang, J.5    Wu, X.6    Sun, X.7    Wu, Z.8
  • 22
    • 33748787130 scopus 로고    scopus 로고
    • Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica
    • Sekiya, M., Mulcahy, G., Irwin, J. A., Stack, C. M., Donnelly, S. M., Xu, W., Collins, P., and Dalton, J. P. (2006) Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica. FEBS Lett. 580, 5016-5022
    • (2006) FEBS Lett. , vol.580 , pp. 5016-5022
    • Sekiya, M.1    Mulcahy, G.2    Irwin, J.A.3    Stack, C.M.4    Donnelly, S.M.5    Xu, W.6    Collins, P.7    Dalton, J.P.8
  • 23
    • 79958060438 scopus 로고    scopus 로고
    • A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides
    • Robinson, M. W., Donnelly, S., Hutchinson, A. T., To, J., Taylor, N. L., Norton, R. S., Perugini, M. A., and Dalton, J. P. (2011) A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides. PLoS Pathog. 7, e1002042
    • (2011) PLoS Pathog. , vol.7 , pp. e1002042
    • Robinson, M.W.1    Donnelly, S.2    Hutchinson, A.T.3    To, J.4    Taylor, N.L.5    Norton, R.S.6    Perugini, M.A.7    Dalton, J.P.8
  • 27
    • 0037108887 scopus 로고    scopus 로고
    • Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search
    • Keller, A., Nesvizhskii, A. I., Kolker, E., and Aebersold, R. (2002) Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal. Chem. 74, 5383-5392
    • (2002) Anal. Chem. , vol.74 , pp. 5383-5392
    • Keller, A.1    Nesvizhskii, A.I.2    Kolker, E.3    Aebersold, R.4
  • 28
    • 0042338362 scopus 로고    scopus 로고
    • A statistical model for identifying proteins by tandem mass spectrometry
    • Nesvizhskii, A. I., Keller, A., Kolker, E., and Aebersold, R. (2003) A statistical model for identifying proteins by tandem mass spectrometry. Anal. Chem. 75, 4646-4658
    • (2003) Anal. Chem. , vol.75 , pp. 4646-4658
    • Nesvizhskii, A.I.1    Keller, A.2    Kolker, E.3    Aebersold, R.4
  • 31
    • 0021277915 scopus 로고
    • Inhibition of aminopeptidases by amastatin and bestatin derivatives. Effect of inhibitor structure on slow-binding processes
    • Rich, D. H., Moon, B. J., and Harbeson, S. (1984) Inhibition of aminopeptidases by amastatin and bestatin derivatives. Effect of inhibitor structure on slow-binding processes. J. Med. Chem. 27, 417-422
    • (1984) J. Med. Chem. , vol.27 , pp. 417-422
    • Rich, D.H.1    Moon, B.J.2    Harbeson, S.3
  • 32
    • 0034768785 scopus 로고    scopus 로고
    • Development of the vitellaria of the liver fluke, Fasciola hepatica in the rat host
    • Robinson, M. W., Colhoun, L. M., Fairweather, I., Brennan, G. P., and Waite, J. H. (2001) Development of the vitellaria of the liver fluke, Fasciola hepatica in the rat host. Parasitology 123, 509-518
    • (2001) Parasitology , vol.123 , pp. 509-518
    • Robinson, M.W.1    Colhoun, L.M.2    Fairweather, I.3    Brennan, G.P.4    Waite, J.H.5
  • 33
    • 74649085604 scopus 로고    scopus 로고
    • Elucidating the transcriptome of Fasciola hepatica - A key to fundamental and biotechnological discoveries for a neglected parasite
    • Young, N. D., Hall, R. S., Jex, A. R., Cantacessi, C., and Gasser, R. B. (2010) Elucidating the transcriptome of Fasciola hepatica - a key to fundamental and biotechnological discoveries for a neglected parasite. Biotechnol. Adv. 28, 222-231
    • (2010) Biotechnol. Adv. , vol.28 , pp. 222-231
    • Young, N.D.1    Hall, R.S.2    Jex, A.R.3    Cantacessi, C.4    Gasser, R.B.5
  • 34
    • 0031894438 scopus 로고    scopus 로고
    • Characterization and partial purification of a leucine aminopeptidase from Fasciola hepatica
    • Acosta, D., Goñi, F., and Carmona, C. (1998) Characterization and partial purification of a leucine aminopeptidase from Fasciola hepatica. J. Parasitol. 84, 1-7
    • (1998) J. Parasitol. , vol.84 , pp. 1-7
    • Acosta, D.1    Goñi, F.2    Carmona, C.3
  • 35
    • 34447559579 scopus 로고    scopus 로고
    • The major secreted cathepsin L1 protease of the liver fluke, Fasciola hepatica: A Leu-12 to Pro-12 replacement in the nonconserved C-terminal region of the prosegment prevents complete enzyme autoactivation and allows definition of the molecular events in prosegment removal
    • Stack, C. M., Donnelly, S., Lowther, J., Xu, W., Collins, P. R., Brinen, L. S., and Dalton, J. P. (2007) The major secreted cathepsin L1 protease of the liver fluke, Fasciola hepatica: a Leu-12 to Pro-12 replacement in the nonconserved C-terminal region of the prosegment prevents complete enzyme autoactivation and allows definition of the molecular events in prosegment removal. J. Biol. Chem. 282, 16532-16543
    • (2007) J. Biol. Chem. , vol.282 , pp. 16532-16543
    • Stack, C.M.1    Donnelly, S.2    Lowther, J.3    Xu, W.4    Collins, P.R.5    Brinen, L.S.6    Dalton, J.P.7
  • 39
    • 84857309195 scopus 로고    scopus 로고
    • The ESCRT machinery
    • Schmidt, O., and Teis, D. (2012) The ESCRT machinery. Curr. Biol. 22, R116-120
    • (2012) Curr. Biol. , vol.22 , pp. R116-120
    • Schmidt, O.1    Teis, D.2
  • 40
    • 0033995763 scopus 로고    scopus 로고
    • Fasciola hepatica: Parasite-secreted proteinases degrade all human IgG subclasses: Determination of the specific cleavage sites and identification of the immunoglobulin fragments produced
    • Berasain, P., Carmona, C., Frangione, B., Dalton, J. P., and Goñi, F. (2000) Fasciola hepatica: parasite-secreted proteinases degrade all human IgG subclasses: determination of the specific cleavage sites and identification of the immunoglobulin fragments produced. Exp. Parasitol. 94, 99-110
    • (2000) Exp. Parasitol. , vol.94 , pp. 99-110
    • Berasain, P.1    Carmona, C.2    Frangione, B.3    Dalton, J.P.4    Goñi, F.5
  • 42
    • 84875166521 scopus 로고    scopus 로고
    • Intestinal innate immune cells in gut homeostasis and immunosurveillance
    • Tomasello, E and Bedoui, S. (2013) Intestinal innate immune cells in gut homeostasis and immunosurveillance. Immunol. Cell Biol. 91, 201-203
    • (2013) Immunol. Cell Biol. , vol.91 , pp. 201-203
    • Tomasello, E.1    Bedoui, S.2
  • 43
    • 84880045106 scopus 로고    scopus 로고
    • Immunomodulatory molecules of Fasciola hepatica: Candidates for both vaccine and immunotherapeutic development
    • Dalton, J. P., Robinson, M. W., Mulcahy, G., O'Neill, S. M., and Donnelly, S. (2013) Immunomodulatory molecules of Fasciola hepatica: candidates for both vaccine and immunotherapeutic development. Vet. Parasitol. 195, 272-285
    • (2013) Vet. Parasitol. , vol.195 , pp. 272-285
    • Dalton, J.P.1    Robinson, M.W.2    Mulcahy, G.3    O'Neill, S.M.4    Donnelly, S.5
  • 44
    • 11144316758 scopus 로고    scopus 로고
    • Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages
    • Donnelly, S., O'Neill, S. M., Sekiya, M., Mulcahy, G., and Dalton, J. P. (2005) Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages. Infect. Immun. 73, 166-173
    • (2005) Infect. Immun. , vol.73 , pp. 166-173
    • Donnelly, S.1    O'Neill, S.M.2    Sekiya, M.3    Mulcahy, G.4    Dalton, J.P.5
  • 45
    • 55549093092 scopus 로고    scopus 로고
    • Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages
    • Donnelly, S., Stack, C. M., O'Neill, S. M., Sayed, A. A., Williams, D. L., Dalton, J. P. (2008) Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages. FASEB J. 22, 4022-4032
    • (2008) FASEB J. , vol.22 , pp. 4022-4032
    • Donnelly, S.1    Stack, C.M.2    O'Neill, S.M.3    Sayed, A.A.4    Williams, D.L.5    Dalton, J.P.6
  • 46
    • 76749151944 scopus 로고    scopus 로고
    • Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses
    • Dowling, D. J., Hamilton, C. M., Donnelly, S., La Course, J., Brophy, P. M., Dalton, J., and O'Neill, S.M. (2010) Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses. Infect. Immun. 78, 793-801
    • (2010) Infect. Immun. , vol.78 , pp. 793-801
    • Dowling, D.J.1    Hamilton, C.M.2    Donnelly, S.3    La Course, J.4    Brophy, P.M.5    Dalton, J.6    O'Neill, S.M.7
  • 47
    • 84915757933 scopus 로고    scopus 로고
    • Fasciola hepatica Kunitz type molecule decreases dendritic cell activation and their ability to induce inflammatory responses
    • Falcón, C. R., Masih, D., Gatti, G., Sanchez, M. C., Motrán, C. C., and Cervi, L. Fasciola hepatica Kunitz type molecule decreases dendritic cell activation and their ability to induce inflammatory responses. PLoS ONE. 9:e114505, 2014
    • (2014) PLoS ONE. , vol.9 , pp. e114505
    • Falcón, C.R.1    Masih, D.2    Gatti, G.3    Sanchez, M.C.4    Motrán, C.C.5    Cervi, L.6
  • 48
    • 84927632666 scopus 로고    scopus 로고
    • Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide (2015) in vitro and in vivo
    • Martin, I., Cabán-Hernández, K., Figueroa-Santiago, O., and Espino, A. M. Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide (2015) in vitro and in vivo. J. Immunol. 194, 3924-3936
    • J. Immunol. , vol.194 , pp. 3924-3936
    • Martin, I.1    Cabán-Hernández, K.2    Figueroa-Santiago, O.3    Espino, A.M.4
  • 50
    • 34548857335 scopus 로고    scopus 로고
    • Inside, outside, upside down: Damageassociated molecular-pattern molecules (DAMPs) and redox
    • Rubartelli, A., and Lotze, M. (2007) Inside, outside, upside down: damageassociated molecular-pattern molecules (DAMPs) and redox. Trends. Immunol. 28, 429-436
    • (2007) Trends. Immunol. , vol.28 , pp. 429-436
    • Rubartelli, A.1    Lotze, M.2
  • 52
    • 39749084641 scopus 로고    scopus 로고
    • Active caspase-1 is a regulator of unconventional protein secretion
    • Keller, M., Rüegg, A., Werner, S., and Beer, H. D. (2008) Active caspase-1 is a regulator of unconventional protein secretion. Cell 132, 818-831
    • (2008) Cell , vol.132 , pp. 818-831
    • Keller, M.1    Rüegg, A.2    Werner, S.3    Beer, H.D.4
  • 53
    • 34548614009 scopus 로고    scopus 로고
    • Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
    • Qu, Y., Franchi, L., Nunez, G., and Dubyak, G. R. (2007) Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J. Immunol. 179, 1913-1925
    • (2007) J. Immunol. , vol.179 , pp. 1913-1925
    • Qu, Y.1    Franchi, L.2    Nunez, G.3    Dubyak, G.R.4
  • 54
    • 34848889680 scopus 로고    scopus 로고
    • Mechanisms for Hsp70 secretion: Crossing membranes without a leader
    • Mambula, S. S., Stevenson, M. A., Ogawa, K., and Calderwood, S.K. (2007) Mechanisms for Hsp70 secretion: crossing membranes without a leader. Methods 43, 168-175
    • (2007) Methods , vol.43 , pp. 168-175
    • Mambula, S.S.1    Stevenson, M.A.2    Ogawa, K.3    Calderwood, S.K.4
  • 58
    • 0035918259 scopus 로고    scopus 로고
    • Rab8b and its interacting partner TRIP8b are involved in regulated secretion in AtT20 cells
    • Chen, S., Liang, M. C., Chia, J. N., Ngsee, J. K., and Ting, A. E. (2001) Rab8b and its interacting partner TRIP8b are involved in regulated secretion in AtT20 cells. J. Biol. Chem. 276, 13209-13216
    • (2001) J. Biol. Chem. , vol.276 , pp. 13209-13216
    • Chen, S.1    Liang, M.C.2    Chia, J.N.3    Ngsee, J.K.4    Ting, A.E.5
  • 59
    • 12744269555 scopus 로고    scopus 로고
    • Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner
    • Savina, A., Fader, C. M., Damiani, M. T., and Colombo, M. I. (2005) Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner. Traffic 6, 131-143
    • (2005) Traffic , vol.6 , pp. 131-143
    • Savina, A.1    Fader, C.M.2    Damiani, M.T.3    Colombo, M.I.4
  • 61
    • 77957731333 scopus 로고    scopus 로고
    • Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion
    • Johnson, C. P., and Chapman, E. R. (2010) Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion. J. Cell Biol. 191, 187-197
    • (2010) J. Cell Biol. , vol.191 , pp. 187-197
    • Johnson, C.P.1    Chapman, E.R.2
  • 62
    • 84857976978 scopus 로고    scopus 로고
    • Biochemical characterization and differential expression of a 16.5-kilodalton tegument-associated antigen from the liver fluke Fasciola hepatica
    • Gaudier, J. F., Cabán-Hernández, K., Osuna, A., and Espino, A. M. (2012) Biochemical characterization and differential expression of a 16.5-kilodalton tegument-associated antigen from the liver fluke Fasciola hepatica. Clin. Vaccine. Immunol. 19, 325-333
    • (2012) Clin. Vaccine. Immunol. , vol.19 , pp. 325-333
    • Gaudier, J.F.1    Cabán-Hernández, K.2    Osuna, A.3    Espino, A.M.4
  • 64
    • 84894273142 scopus 로고    scopus 로고
    • Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: Insights into the structural integrity of the schistosomal tegument
    • Leow, C. Y., Willis, C., Osman, A., Mason, L., Simon, A., Smith, B. J., Gasser, R. B., Jones, M. K., and Hofmann, A. (2014) Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument. FEBS J. 281, 1209-1225
    • (2014) FEBS J. , vol.281 , pp. 1209-1225
    • Leow, C.Y.1    Willis, C.2    Osman, A.3    Mason, L.4    Simon, A.5    Smith, B.J.6    Gasser, R.B.7    Jones, M.K.8    Hofmann, A.9
  • 67
  • 68
    • 84910603096 scopus 로고    scopus 로고
    • Moonlighting proteins as virulence factors of pathogenic fungi, parasitic protozoa and multicellular parasites
    • Karkowska-Kuleta, J., and Kozik, A. (2014) Moonlighting proteins as virulence factors of pathogenic fungi, parasitic protozoa and multicellular parasites. Mol. Oral. Microbiol. 29, 270-283
    • (2014) Mol. Oral. Microbiol. , vol.29 , pp. 270-283
    • Karkowska-Kuleta, J.1    Kozik, A.2
  • 69
    • 0029151459 scopus 로고
    • Cloning and molecular characterization of two genes encoding adhesion proteins involved in Trichomonas vaginalis cytoadherence
    • Alderete, J. F., O'Brien, J. L., Arroyo, R., Engbring, J. A., Musatovova, O., Lopez, O., Lauriano, C., and Nguyen, J. (1995) Cloning and molecular characterization of two genes encoding adhesion proteins involved in Trichomonas vaginalis cytoadherence. Mol. Microbiol. 17, 69-83
    • (1995) Mol. Microbiol. , vol.17 , pp. 69-83
    • Alderete, J.F.1    O'Brien, J.L.2    Arroyo, R.3    Engbring, J.A.4    Musatovova, O.5    Lopez, O.6    Lauriano, C.7    Nguyen, J.8
  • 70
    • 1842636779 scopus 로고    scopus 로고
    • Identification of enolase as a plasminogenbinding protein in excretory-secretory products of Fasciola hepatica
    • Bernal, D., de la Rubia, J. E., Carrasco-Abad, A. M., Toledo, R., Mas-Coma, S., and Marcilla, A. (2004) Identification of enolase as a plasminogenbinding protein in excretory-secretory products of Fasciola hepatica. FEBS Lett. 563, 203-206
    • (2004) FEBS Lett. , vol.563 , pp. 203-206
    • Bernal, D.1    De La Rubia, J.E.2    Carrasco-Abad, A.M.3    Toledo, R.4    Mas-Coma, S.5    Marcilla, A.6
  • 71
    • 67650032436 scopus 로고    scopus 로고
    • Glyceraldehyde- 3-phosphate dehydrogenase is a surface-associated, fibronectin- binding protein of Trichomonas vaginalis
    • Lama, A., Kucknoor, A., Mundodi, V., and Alderete, J. F. (2009) Glyceraldehyde- 3-phosphate dehydrogenase is a surface-associated, fibronectin- binding protein of Trichomonas vaginalis. Infect. Immun. 77, 2703-2711
    • (2009) Infect. Immun. , vol.77 , pp. 2703-2711
    • Lama, A.1    Kucknoor, A.2    Mundodi, V.3    Alderete, J.F.4
  • 73
    • 84883740186 scopus 로고    scopus 로고
    • Parasitism in optima forma: Exploiting the host fibrinolytic system for invasion
    • Figuera, L., Gómez-Arreaza, A., and Avilán, L. (2013) Parasitism in optima forma: exploiting the host fibrinolytic system for invasion. Acta Trop. 128, 116-123
    • (2013) Acta Trop. , vol.128 , pp. 116-123
    • Figuera, L.1    Gómez-Arreaza, A.2    Avilán, L.3
  • 74
    • 84880749272 scopus 로고    scopus 로고
    • Surface associated antigens of Dirofilaria immitis adult worms activate the host fibrinolytic system
    • González-Miguel, J., Morchón, R., Carretón, E., Montoya-Alonso, J. A., and Simón, F. (2013) Surface associated antigens of Dirofilaria immitis adult worms activate the host fibrinolytic system. Vet. Parasitol. 196, 235-240
    • (2013) Vet. Parasitol. , vol.196 , pp. 235-240
    • González-Miguel, J.1    Morchón, R.2    Carretón, E.3    Montoya-Alonso, J.A.4    Simón, F.5


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