Methylation of IL-2 promoter at birth alters the risk of asthma exacerbations during childhood

Clinical and Experimental Allergy

Volumn 43, Issue 3, 2013, Pages 304-311

  Curtin, J A ^a   Simpson, A ^a   Belgrave, D ^a   Semic Jusufagic, A ^a   Custovic, A ^a   Martinez, F D ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Asthma; Childhood; Epigenetics; Exacerbation; Interleukin 2; Methylation

Indexed keywords

INTERLEUKIN 2; PHYTOHEMAGGLUTININ;

AGING; ARTICLE; ASTHMA; ATOPY; BIRTH; BRONCHIOLITIS; CHILD; CHILD HOSPITALIZATION; CHILDHOOD DISEASE; CONTROLLED STUDY; CPG ISLAND; DISEASE EXACERBATION; DISEASE SEVERITY; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENETIC RISK; HOSPITAL ADMISSION; HUMAN; HUMAN CELL; INFANT; LONG INTERSPERSED REPEAT; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MONONUCLEAR CELL; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; SCHOOL CHILD; SENSITIZATION; TRANSCRIPTION REGULATION; UMBILICAL CORD BLOOD; WHEEZING;

ASTHMA; CHILD; CHILD, PRESCHOOL; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; HOSPITALIZATION; HUMANS; INFANT; INFANT, NEWBORN; INTERLEUKIN-2; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROMOTER REGIONS, GENETIC; RISK; RISK FACTORS;

EID: 84873949933     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/cea.12046     Document Type: Article

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