Exacerbation of lupus nephritis by high sodium chloride related to activation of SGK1 pathway

International Immunopharmacology

Volumn 29, Issue 2, 2015, Pages 568-573

  Yang, Xi ^a   Yao, Genhong ^a   Chen, Weiwei ^a   Tang, Xiaojun ^a   Feng, Xuebing ^a   Sun, Lingyun ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

High salt diet; Lupus nephritis; Serum and glucocorticoid inducible serine threonine protein kinase 1

Indexed keywords

IMMUNOGLOBULIN G; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 6; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; CYTOKINE; IMMEDIATE EARLY PROTEIN; PROTEIN SERINE THREONINE KINASE; SALT INTAKE; SERUM-GLUCOCORTICOID REGULATED KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GLOMERULAR STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; SURVIVAL RATE; SYSTEMIC LUPUS ERYTHEMATOSUS; TH1 CELL; TH17 CELL; TH2 CELL; UPREGULATION; ADMINISTRATION AND DOSAGE; ADULT; ANIMAL; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MONONUCLEAR CELL; MURPHY ROTHS LARGE LYMPHOPROLIFERATIVE MOUSE; PATHOLOGY; SALT INTAKE;

ADULT; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMEDIATE-EARLY PROTEINS; LEUKOCYTES, MONONUCLEAR; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; MICE; MICE, INBRED MRL LPR; PROTEIN-SERINE-THREONINE KINASES; SODIUM CHLORIDE; SODIUM CHLORIDE, DIETARY; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 84948456547     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.09.027     Document Type: Article

References (28)

1. N. Schwartz, B. Goilav, and C. Putterman The pathogenesis, diagnosis and treatment of lupus nephritis Curr. Opin. Rheumatol. 26 2014 502 509
2. J. Du, Z. Li, J. Shi, and L. Bi Association between serum interleukin-23 levels and clinical characteristics in patients with systemic lupus erythematosus J Int Med Res 42 2014 1123 1130
3. M. Hatherill Rubbing salt in the wound Arch. Dis. Child. 89 2004 414 418
4. J. Habibi, M.R. Hayden, C.M. Ferrario, J.R. Sowers, and A.T. Whaley-Connell Salt loading promotes kidney injury via fibrosis in young female ren2 rats Cardiorenal Med 4 2014 43 52
5. W.G.L.F. Junger, W.H. Loomis, and D.B. Hoyt Hypertonic saline enhances cellular immune function Circ. Shock. 42 1994 190 196
6. C. Wu, N. Yosef, T. Thalhamer, and et al. Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1 Nature 496 2013 513 517
7. M. Kleinewietfeld, A. Manzel, J. Titze, and et al. Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells Nature 496 2013 518 522
8. K.W. Mathis, M. Veneqas-Pont, C.W. Masterson, K.L. Wasson, and M.J. Ryan Blood pressure in a hypertensive mouse model of SLE is not salt-sensitive Am J Physiol Regul Inteqr Comp Physiol 301 2011 R1281 R1285
9. Y. Li, K.J. Yang, and J. Park Multiple implications of 3-phosphoinositide-dependent protein kinase 1 in human cancer World J Biol Chem 1 2010 239 247
10. M. Sobiesiak, E. Shumilina, R.S. Lam, F. Wolbing, N. Matzner, S. Kaesler, and et al. Impaired mast cell activation in gene-targeted mice lacking the serum- and glucocorticoid-inducible kinase SGK1 J. Immunol. 183 2009 4395 4402
11. F. Lang, F. Artunc, and V. Vallon The physiological impact of the serum and glucocorticoid-inducible kinase SGK1 Curr. Opin. Nephrol. Hypertens. 18 2009 439 448
12. L. Li, C.S. Wingo, and S.L. Xia Downregulation of SGK1 by nucleotides in renal tubular epithelial cells Am J Physiol Renal Physiol 293 2007 F1751 F1757
13. F. Lang, C. Böhmer, M. Palmada, G. Seebohm, N. Strutz-Seebohm, and V. Vallon (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms Physiol. Rev. 86 2006 1151 1178
14. M.C. Hochberg Updating the American College of Rheumatology revised criteria for classifications of systemic lupus erythematosus Arthritis Rheum. 40 1997 1725 1726
15. F. Guarneri, and S. Benvenga Environmental factors and genetic background that interact to cause autoimmune thyroid disease Curr Opin Endocrinol Diabetes Obes 14 2007 398 409
16. B. Rodriguez-lturbe, N.D. Vaziri, J. Herrera-Acosta, and R.J. Johnson Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all Am J Physiol Renal Physiol 286 2004 F606 F616
17. S. Takahashi, L. Fossati, M. Iwamoto, and et al. Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice J. Clin. Invest. 97 1996 1597 1604
18. M. Noack, and P. Miossec Th17 and regulatory T cell balance in autoimmune and inflammatory diseases Autoimmun. Rev. 13 2014 668 677
19. Gigante A, Gasperini ML, Afeltra A, et al. Cytokines expression in SLE nephritis. Eur Rev Med Pharmacol Sci 2011; 15: 15-24.
20. Y. Wang, S. Ito, Y. Chino, and et al. Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis Clin. Exp. Immunol. 159 2010 1 10
21. H. Tan, J. Zhao, S. Wang, and et al. Ac-SDKP ameliorates the progression of lupus nephritis in MRL/lpr mice Int. Immunopharmacol. 14 2012 401 409
22. S. Lee, H.J. Hwang, and Y. Kim Modeling the role of TGF-β in regulation of the Th17 phenotype in LPS-driven immune system Bull. Math. Biol. 76 2014 1045 1080
23. S. Ikeda, S. Saijo, M.A. Murayama, K. Shimizu, A. Akitsu, and Y. Iwakura Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-β-induced Foxp3 expression J. Immunol. 192 2014 1449 1458
24. J.P. Edwards, H. Fujii, A.X. Zhou, J. Creemers, D. Unutmaz, and E.M. Shevach Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation J. Immunol. 190 2013 5506 5515
25. L. Yao, H.P. Chen, and Q. Ma Piperlongumine alleviates lupus nephritis in MRL-Fas (lpr) mice by regulating the frequency of Th17 and regulatory T cells Immunol. Lett. 161 2014 76 80
26. J.C. Martin, D.L. Baeten, and R. Josien Emerging role of IL-17 and Th17 cells in systemic lupus erythematosus Clin. Immunol. 154 2014 1 12
27. N. Likuni, E.V. Lourenço, B.H. Hahn, and A. La Cava Cutting edge: regulatory T cells directly suppress B cells in systemic lupus erythematosus J. Immunol. 183 2009 1518 1522
28. F. Lang, D.Y. Huang, and V. Vallon SGK, renal function and hypertension J Nephrol 23 Suppl 16 2010 124 129