Downregulation of SGK1 by nucleotides in renal tubular epithelial cells

American Journal of Physiology - Renal Physiology

Volumn 293, Issue 5, 2007, Pages

  Li, Liuzhe ^a   Wingo, Charles S ^a   Xia, Shen Ling ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Epithelial sodium channels; Mineralocorticoid receptor; Phosphatidylinositol 4,5 bisphosphate; Purinergic signaling; Renal ion transport; Serum and glucocorticoid inducible kinase 1

Indexed keywords

ADENOSINE 5' O (3 THIOTRIPHOSPHATE); ALDOSTERONE; MINERALOCORTICOID RECEPTOR; NUCLEOTIDE; PURINE P2 RECEPTOR; PURINE RECEPTOR; RECEPTOR SUBTYPE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; KIDNEY COLLECTING TUBULE; KIDNEY TUBULE EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; WESTERN BLOTTING;

EID: 36049004368     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00091.2007     Document Type: Article

References (31)

1. Brickley DR, Mikosz CA, Hagan CR, Conzen SD. Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1). J Biol Chem 277: 43064-43070, 2002.
2. Buse P, Tran SH, Luther E, Phu PT, Aponte GW, Firestone GL. Cell cycle and hormonal control of nuclear-cytoplasmic localization of the serum- and glucocorticoid-inducible protein kinase, Sgk, in mammary tumor cells. J Biol Chem 274: 7253-7263, 1999.
3. Gumz ML, Popp MP, Wingo CS, Cain BD. Early transcriptional effects of aldosterone in a mouse inner medullary collecting duct cell line. Am J Physiol Renal Physiol 285: F664-F673, 2003.
4. + transport. Am J Physiol Renal Physiol 283: F377-F387, 2002.
5. Kobayashi T, Cohen P. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2. Biochem J 339: 319-328, 1999.
6. 2+ signaling. Am J Physiol Renal Fluid Electrolyte Physiol 270: F53-F60, 1996.
7. + absorption by extracellular nucleotides in mouse trachea. Pflügers Arch 444: 220-226, 2002.
8. 2. FASEB J 19: 142-143, 2005.
9. 1 receptors. Eur J Pharmacol 387: R19-R21, 2000.
10. Lang F, Böhmer C, Palmada M, Seebohm G, Strutz-Seebohm N, Vallon V. (Patho)physiological significance of the serum- and glucocorticoid- inducible kinase isoforms. Physiol Rev 86: 1151-1178, 2006.
11. Lang F, Cohen P. Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms. Sci STKE 13: 1-13, 2001.
12. + absorption in isolated perfused mouse CCD. J Am Soc Nephrol 13: 10-18, 2002.
13. Leipziger J. Control of epithelial transport via luminal P2 receptors. Am J Physiol Renal Physiol 284: F419-F432, 2003.
14. Loffing J, Zecevic M, Feraille E, Kaissling B, Asher C, Rossier BC, Firestone GL, Pearce D, Verrey F. Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK. Am J Physiol Renal Physiol 280: F675-F682, 2001.
15. Ma HP, Li L, Zhou ZH, Eaton DC, Warnock DG. ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells. Am J Physiol Renal Physiol 282: F501-F505, 2002.
16. Ma HP, Saxena S, Warnock DG. Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC). J Biol Chem 277: 7641-7644, 2002.
17. McCoy DE, Taylor AL, Kudlow BA, Karlson K, Slattery MJ, Schwiebert LM, Schwiebert EM, Stanton BA. Nucleotides regulate NaCl transport in mIMCD-K2 cells via P2X and P2Y purinergic receptors. Am J Physiol Renal Physiol 277: F552-F559, 1999.
18. North RA. Molecular physiology of P2X receptors. Physiol Rev 82: 1013-1067, 2002.
19. Park J, Leong ML, Buse P, Maiyar AC, Firestone GL, Hemmings BA. Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway. EMBO J 18: 3024-3033, 1999.
20. + channel (ENaC) by phosphatidylinositides. Am J Physiol Renal Physiol 290: F949-F957, 2006.
21. Rauchman MI, Nigam SK, Delpire E, Gullans SR. An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse. Am J Physiol Renal Fluid Electrolyte Physiol 265: F416-F424, 1993.
22. Rhee SG. Regulation of phosphoinsitide-specific phospholipase C. Annu Rev Biochem 70: 281-312, 2001.
23. Schwiebert EM, Kishore BK. Extracellular nucleotide signaling along the renal epithelium. Am J Physiol Renal Physiol 280: F945-F963, 2001.
24. Shirley DG, Bailey MA, Unwin RJ. In vivo stimulation of apical P2 receptors in collecting ducts: evidence for inhibition of sodium reabsorption. Am J Physiol Renal Physiol 288: F1243-F1248, 2005.
25. Unwin RJ, Bailey MA, Burnstock G. Purinergic signaling along the renal tubule: the current state of play. News Physiol Sci 18: 237-241, 2003.
26. Vallon V, Lang F. New insights into the role of serum- and glucocorticoid-inducible kinase SGK1 in the regulation of renal function and blood pressure. Curr Opin Nephrol Hypertens 14: 59-66, 2005.
27. Wang J, Barbry P, Maiyar AC, Rozansky DJ, Bhargava A, Leong M, Firestone GL, Pearce D. SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport. Am J Physiol Renal Physiol 280: F303-F313, 2001.
28. Wei Y, Sun P, Wang Z, Yang B, Carroll MA, Wang WH. Adenosine inhibits ENaC via cytochrome P-450 epoxygenase-dependent metabolites of arachidonic acid. Am J Physiol Renal Physiol 290: F1163-F1168, 2006.
29. + channels and P2X receptors. J Am Soc Nephrol 16: 2586-2597, 2005.
30. Xia SL, Wang L, Cash MN, Teng X, Schwalbe RA, Wingo CS. Extracellular ATP- induced calcium signaling in mIMCD-3 cells requires both P2X and P2Y purinoceptors. Am J Physiol Renal Physiol 287: F204-F214, 2004.
31. 2+ influx via P2X receptors (P2XRs) in mIMCD-3 cells (Abstract). J Am Soc Nephrol 15: 86A, 2004.