Investigating the neural correlates of schemas: Ventromedial prefrontal cortex is necessary for normal schematic influence on memory

Journal of Neuroscience

Volumn 35, Issue 47, 2015, Pages 15746-15751

  Spalding, Kelsey N ^a   Jones, Samuel H ^c   Duff, Melissa C ^b,c   Tranel, Daniel ^a,c   Warren, David E ^c  

^a Departments of 1Psychological and Brain Sciences   (United States)

^b Department of English   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

Contextual congruence; False recognition; Schema; Schematic memory; Ventromedial prefrontal cortex; VmPFC

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; HUMAN; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; LOGISTIC REGRESSION ANALYSIS; MALE; MEMORY; MIDDLE AGED; NEUROPSYCHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; PRIORITY JOURNAL; TEMPORAL LOBE; AGED; EPISODIC MEMORY; NERVE TRACT; PHOTOSTIMULATION; PHYSIOLOGY; PROCEDURES; RECALL;

AGED; FEMALE; HUMANS; MALE; MEMORY, EPISODIC; MENTAL RECALL; MIDDLE AGED; NEURAL PATHWAYS; PHOTIC STIMULATION; PREFRONTAL CORTEX;

EID: 84948170759     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2767-15.2015     Document Type: Article

References (33)

1. Bartlett F (1932) Remembering. Cambridge: Cambridge UP.
2. Bechara A, Damasio AR (2005) The somatic marker hypothesis: a neural theory of economic decision. Games Econ Behav 52:336-372. CrossRef
3. Bonnici HM, Chadwick MJ, Lutti A, Hassabis D, Weiskopf N, Maguire EA (2012) Detecting representations of recent and remote autobiographical memories in vmPFC and hippocampus. J Neurosci 32:16982-16991. CrossRef Medline
4. Castel AD, McGillivray S, Worden KM (2013) Back to the future: past and future era-based schematic support and associative memory for prices in younger and older adults. Psychol Aging 28:996-1003. CrossRef Medline
5. Cavada C, Compañy T, Tejedor J, Cruz-Rizzolo RJ, Reinoso-Suárez F (2000) The anatomical connections of the macaque monkey orbitofrontal cortex: a review. Cereb Cortex 10:220-242. CrossRef Medline
6. della Rocchetta AI, Milner B (1993) Strategic search and retrieval inhibition: the role of the frontal lobes. Neuropsychologia 31:501-524.
7. Denburg NL, Cole CA, Hernandez M, Yamada TH, Tranel D, Bechara A, Wallace RB (2007) The orbitofrontal cortex, real-world decision making, and normal aging. Ann NY Acad Sci 1121:480-498. CrossRef Medline
8. Euston DR, McNaughton BL (2006) Apparent encoding of sequential context in rat medial prefrontal cortex is accounted for by behavioral variability. J Neurosci 26: 13143-13155. CrossRef Medline
9. Fjell AM, Westlye LT, Grydeland H, Amlien I, Espeseth T, Reinvang I, Raz N, Holland D, Dale AM, Walhovd KB (2013) Critical ages in the life course of the adult brain: nonlinear subcortical aging. Neurobiol Aging 34: 2239-2247. CrossRef Medline
10. Frank RJ, Damasio H, Grabowski TJ (1997) Brainvox: an interactive, multimodal visualization and analysis system for neuroanatomical imaging. Neuroimage 5:13-30. CrossRef Medline
11. Gershberg FB, Shimamura AP (1995) Impaired use of organizational strategies in free recall following frontal lobe damage. Neuropsychologia 33: 1305-1333. CrossRef Medline
12. Ghosh VE, Moscovitch M, Melo Colella B, Gilboa A (2014). Schema representation in patients with ventromedial PFC lesions. J Neurosci 34: 12057-12070. CrossRef Medline
13. Halekoh U, Højsgaard S (2012) A Kenward-Roger approximation and parametric bootstrap methods for tests in linear mixed models— the R package pbkrtest. J Stat Softw 59. Retrieved from http://people. math.aau.dk/_sorenh/software/pbkrtest/doc/pbkrtest-JSS.pdf.
14. Hyman JM, Zilli EA, Paley AM, Hasselmo ME (2010) Working memory performance correlates with prefrontal-hippocampal theta interactions but not with prefrontal neuron firing rates. Front Integr Neurosci 4:2. CrossRef Medline
15. Koriat A, Goldsmith M, Pansky A (2000) Toward a psychology of memory accuracy. Annu Rev Psychol 51:481-537. Medline
16. Kumaran D, Summerfield JJ, Hassabis D, Maguire EA (2009) Tracking the emergence of conceptual knowledge during human decision making. Neuron 63:889-901. CrossRef Medline
17. Kumaran D, Warren DE, Tranel D (2015) Damage to the ventromedial prefrontal cortex impairs learning from observed outcomes. Cereb Cortex.
18. Lewis PA, Durrant SJ (2011) Overlapping memory replay during sleep builds cognitive schemata. Trends Cogn Sci 15:343-351. CrossRef Medline
19. Melo B, Winocur G, Moscovitch M (1999) False recall and false recognition: an examination of the effects of selective and combined lesions to the medial temporal lobe/diencephalon and frontal lobe structures. Cogn Neuropsychol 16: 343-359. CrossRef
20. Morris RG (2006) Elements of a neurobiological theory of hippocampal function: the role of synaptic plasticity, synaptic tagging and schemas. Eur J Neurosci 23:2829-2846. CrossRef Medline
21. Moscovitch M, Winocur G (1995) Frontal lobes, memory, and aging. Ann NY Acad Sci 769:119-150. CrossRef Medline
22. Palmer TE (1975) The effects of contextual scenes on the identification of objects. Mem Cognit 3:519-526. CrossRef Medline
23. Ranganath C, Heller A, Cohen MX, Brozinsky CJ, Rissman J (2005) Functional connectivity with the hippocampus during successful memory formation. Hippocampus 15:997-1005. CrossRef Medline
24. Saleem KS, Kondo H, Price JL (2008) Complementary circuits connecting the orbital and medial prefrontal networks with the temporal, insular, and opercular cortex in the macaque. J Comp Neurol 506:659-693. CrossRef Medline
25. Tse D, Langston RF, Kakeyama M, Bethus I, Spooner PA, Wood ER, Witter MP, Morris RG (2007) Schemas and memory consolidation. Science 316:76-82. CrossRef Medline
26. van Kesteren MT, Rijpkema M, Ruiter DJ, Fernández G (2010) Retrieval of associative information congruent with prior knowledge is related to increased medial prefrontal activity and connectivity. J Neurosci 30: 15888-15894. CrossRef Medline
27. van Kesteren MT, Ruiter DJ, Fernández G, Henson RN (2012) How schema and novelty augment memory formation. Trends Neurosci 35: 211-219. CrossRef Medline
28. van Kesteren MT, Beul SF, Takashima A, Henson RN, Ruiter DJ, Fernández G (2013) Differential roles for medial prefrontal and medial temporal cortices in schema-dependent encoding: from congruent to incongruent. Neuropsychologia 51:2352-2359. CrossRef Medline
29. Wang SH, Morris RG (2010) Hippocampal-neocortical interactions in memory formation, consolidation, and reconsolidation. Annu Rev Psychol 61:49-79, C1-4. CrossRef Medline
30. Warren DE, Jones SH, Duff MC, Tranel D (2014) False recall is reduced by damage to the ventromedial prefrontal cortex: implications for understanding the neural correlates of schematic memory. J Neurosci 34: 7677-7682. CrossRef Medline
31. Yassa MA, Lacy JW, Stark SM, Albert MS, Gallagher M, Stark CE (2011) Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults. Hippocampus 21:968-979. CrossRef Medline
32. Zeithamova D, Schlichting ML, Preston AR (2012a) The hippocampus and inferential reasoning: building memories to navigate future decisions. Front Hum Neurosci 6:70. CrossRef Medline
33. Zeithamova D, Dominick AL, Preston AR (2012b) Hippocampal and ventral medial prefrontal activation during retrieval-mediated learning supports novel inference. Neuron 75:168-179. CrossRef Medline