Dominant genetic variation and missing heritability for human complex traits: Insights from twin versus genome-wide common SNP models

American Journal of Human Genetics

Volumn 97, Issue 5, 2015, Pages 708-714

  Chen, Xu ^a   Kuja Halkola, Ralf ^a   Rahman, Iffat ^a   Arpegård, Johannes ^a,b   Viktorin, Alexander ^a   Karlsson, Robert ^a   Hägg, Sara ^a   Svensson, Per ^a,b   Pedersen, Nancy L ^a   Magnusson, Patrik K E ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CREATININE; CYSTATIN C; GLUCOSE; HEMOGLOBIN; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; IMMUNOGLOBULIN A; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; BODY HEIGHT; BODY MASS; BODY WEIGHT; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIZYGOTIC TWINS; FAMILY STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; GLOMERULUS FILTRATION RATE; HEREDITY; HERITABILITY; HUMAN; MALE; MONOZYGOTIC TWINS; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TWINS; WAIST CIRCUMFERENCE; BIOLOGICAL MODEL; CAUCASIAN; COMPARATIVE STUDY; DOMINANT GENE; ENVIRONMENT; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN GENOME; PROGNOSIS; QUANTITATIVE TRAIT;

AGED; ENVIRONMENT; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENES, DOMINANT; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MODELS, GENETIC; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; QUANTITATIVE TRAIT, HERITABLE; TWINS;

EID: 84947927630     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2015.10.004     Document Type: Article

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