Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy

Cell Stem Cell

Volumn 17, Issue 5, 2015, Pages 569-584

  Ng, Shi Yan ^a,b   Soh, Boon Seng ^a,b,c   Rodriguez Muela, Natalia ^a,b   Hendrickson, David G ^a,d   Price, Feodor ^a,b   Rinn, John L ^a,b,d   Rubin, Lee L ^a,b  

^a Harvard University   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; MESSENGER RNA; RNA; SURVIVAL MOTOR NEURON PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY LABELING; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOTONEURON; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; RNA SEQUENCE; RNA SPLICING; SPINAL CORD VENTRAL HORN; SPINAL MUSCULAR ATROPHY; ANIMAL; CELL CULTURE; CELL DEATH; CELL DIFFERENTIATION; GENETICS; INBRED MOUSE STRAIN; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PATHOLOGY; SEQUENCE ANALYSIS; TRANSGENIC MOUSE;

ANIMALS; CELL DEATH; CELL DIFFERENTIATION; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; RNA; SEQUENCE ANALYSIS, RNA;

EID: 84947867559     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2015.08.003     Document Type: Article

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