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Volumn 29, Issue 3, 2014, Pages 211-216

Molecular pathogenesis and targeted therapies in well-differentiated thyroid carcinoma

Author keywords

Targeted therapies; Thyroid neoplasms

Indexed keywords


EID: 84947797749     PISSN: 2093596X     EISSN: 20935978     Source Type: Journal    
DOI: 10.3803/EnM.2014.29.3.211     Document Type: Review
Times cited : (12)

References (38)
  • 4
    • 0036983115 scopus 로고    scopus 로고
    • The Ras-Raf-MEK-ERK pathway in the treatment of cancer
    • Hilger RA, Scheulen ME, Strumberg D. The Ras-Raf-MEK-ERK pathway in the treatment of cancer. Onkologie 2002;25:511-8.
    • (2002) Onkologie , vol.25 , pp. 511-518
    • Hilger, R.A.1    Scheulen, M.E.2    Strumberg, D.3
  • 9
    • 0035986363 scopus 로고    scopus 로고
    • RET/PTC rearrangement in thyroid tumors
    • Nikiforov YE. RET/PTC rearrangement in thyroid tumors. Endocr Pathol 2002;13:3-16.
    • (2002) Endocr Pathol , vol.13 , pp. 3-16
    • Nikiforov, Y.E.1
  • 11
    • 0033671621 scopus 로고    scopus 로고
    • Prognostic significance of RET and NTRK1 rearrangements in sporadic papillary thyroid carcinoma
    • Musholt TJ, Musholt PB, Khaladj N, Schulz D, Scheumann GF, Klempnauer J. Prognostic significance of RET and NTRK1 rearrangements in sporadic papillary thyroid carcinoma. Surgery 2000;128:984-93.
    • (2000) Surgery , vol.128 , pp. 984-993
    • Musholt, T.J.1    Musholt, P.B.2    Khaladj, N.3    Schulz, D.4    Scheumann, G.F.5    Klempnauer, J.6
  • 14
    • 85047687680 scopus 로고    scopus 로고
    • Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations
    • Zhu Z, Gandhi M, Nikiforova MN, Fischer AH, Nikiforov YE. Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations. Am J Clin Pathol 2003;120:71-7.
    • (2003) Am J Clin Pathol , vol.120 , pp. 71-77
    • Zhu, Z.1    Gandhi, M.2    Nikiforova, M.N.3    Fischer, A.H.4    Nikiforov, Y.E.5
  • 15
    • 0033604576 scopus 로고    scopus 로고
    • Isotype-specific functions of Raf kinases
    • Hagemann C, Rapp UR. Isotype-specific functions of Raf kinases. Exp Cell Res 1999;253:34-46.
    • (1999) Exp Cell Res , vol.253 , pp. 34-46
    • Hagemann, C.1    Rapp, U.R.2
  • 17
    • 5444227865 scopus 로고    scopus 로고
    • Guilty as charged: B-RAF is a human oncogene
    • Garnett MJ, Marais R. Guilty as charged: B-RAF is a human oncogene. Cancer Cell 2004;6:313-9.
    • (2004) Cancer Cell , vol.6 , pp. 313-319
    • Garnett, M.J.1    Marais, R.2
  • 18
    • 0037379904 scopus 로고    scopus 로고
    • High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
    • Kimura ET, Nikiforova MN, Zhu Z, Knauf JA, Nikiforov YE, Fagin JA. High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res 2003;63:1454-7.
    • (2003) Cancer Res , vol.63 , pp. 1454-1457
    • Kimura, E.T.1    Nikiforova, M.N.2    Zhu, Z.3    Knauf, J.A.4    Nikiforov, Y.E.5    Fagin, J.A.6
  • 20
    • 79955751512 scopus 로고    scopus 로고
    • BRAFV600E: implications for carcinogenesis and molecular therapy
    • Cantwell-Dorris ER, O'Leary JJ, Sheils OM. BRAFV600E: implications for carcinogenesis and molecular therapy. Mol Cancer Ther 2011;10:385-94.
    • (2011) Mol Cancer Ther , vol.10 , pp. 385-394
    • Cantwell-Dorris, E.R.1    O'Leary, J.J.2    Sheils, O.M.3
  • 26
    • 84892424941 scopus 로고    scopus 로고
    • Lack of association of BRAF mutation with negative prognostic indicators in papillary thyroid carcinoma: the University of California, San Francisco, experience
    • Gouveia C, Can NT, Bostrom A, Grenert JP, van Zante A, Orloff LA. Lack of association of BRAF mutation with negative prognostic indicators in papillary thyroid carcinoma: the University of California, San Francisco, experience. JAMA Otolaryngol Head Neck Surg 2013;139:1164-70.
    • (2013) JAMA Otolaryngol Head Neck Surg , vol.139 , pp. 1164-1170
    • Gouveia, C.1    Can, N.T.2    Bostrom, A.3    Grenert, J.P.4    van Zante, A.5    Orloff, L.A.6
  • 33
    • 78049462514 scopus 로고    scopus 로고
    • Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation
    • Carr LL, Mankoff DA, Goulart BH, Eaton KD, Capell PT, Kell EM, Bauman JE, Martins RG. Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation. Clin Cancer Res 2010;16:5260-8.
    • (2010) Clin Cancer Res , vol.16 , pp. 5260-5268
    • Carr, L.L.1    Mankoff, D.A.2    Goulart, B.H.3    Eaton, K.D.4    Capell, P.T.5    Kell, E.M.6    Bauman, J.E.7    Martins, R.G.8
  • 34
    • 3042548695 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts
    • Inai T, Mancuso M, Hashizume H, Baffert F, Haskell A, Baluk P, Hu-Lowe DD, Shalinsky DR, Thurston G, Yancopoulos GD, McDonald DM. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am J Pathol 2004;165:35-52.
    • (2004) Am J Pathol , vol.165 , pp. 35-52
    • Inai, T.1    Mancuso, M.2    Hashizume, H.3    Baffert, F.4    Haskell, A.5    Baluk, P.6    Hu-Lowe, D.D.7    Shalinsky, D.R.8    Thurston, G.9    Yancopoulos, G.D.10    McDonald, D.M.11
  • 36
    • 34548189195 scopus 로고    scopus 로고
    • Phase II trial of thalidomide for therapy of radioiodine-unresponsive and rapidly progressive thyroid carcinomas
    • Ain KB, Lee C, Williams KD. Phase II trial of thalidomide for therapy of radioiodine-unresponsive and rapidly progressive thyroid carcinomas. Thyroid 2007;17:663-70.
    • (2007) Thyroid , vol.17 , pp. 663-670
    • Ain, K.B.1    Lee, C.2    Williams, K.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.