Motoric Cognitive Risk Syndrome: Prevalence and Risk Factors in Japanese Seniors

Journal of the American Medical Directors Association

Volumn 16, Issue 12, 2015, Pages 1103.e21-1103.e25

  Doi, Takehiko ^a,b,c   Verghese, Joe ^c   Shimada, Hiroyuki ^a   Makizako, Hyuma ^a   Tsutsumimoto, Kota ^a   Hotta, Ryo ^a   Nakakubo, Sho ^a   Suzuki, Takao ^a,d  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d J F OBERLIN UNIVERSITY   (Japan)

Author keywords

Cognition; Dementia; Gait; Lifestyle

Indexed keywords

AGED; ALCOHOL CONSUMPTION; ARTICLE; CROSS-SECTIONAL STUDY; DEPRESSION; DIABETES MELLITUS; FALLING; FEMALE; HUMAN; JAPANESE (PEOPLE); LIFESTYLE; MAJOR CLINICAL STUDY; MALE; MILD COGNITIVE IMPAIRMENT; MOTOR DYSFUNCTION; MOTORIC COGNITIVE RISK SYNDROME; OBESITY; PHYSICAL INACTIVITY; PREVALENCE; RISK FACTOR; SCREENING; SEX DIFFERENCE; SMOKING; DEMENTIA; GAIT; JAPAN; MOTOR ACTIVITY; PHYSIOLOGY; SYNDROME; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CROSS-SECTIONAL STUDIES; DEMENTIA; FEMALE; GAIT; HUMANS; JAPAN; MALE; MOTOR ACTIVITY; PREVALENCE; RISK FACTORS; SYNDROME;

EID: 84947781612     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2015.09.003     Document Type: Article

References (41)

1. Verghese J., Annweiler C., Ayers E., et al. Motoric cognitive risk syndrome: Multicountry prevalence and dementia risk. Neurology 2014, 83:718-726.
2. Verghese J., Wang C., Lipton R.B., et al. Motoric cognitive risk syndrome and the risk of dementia. J Gerontol A Biol Sci Med Sci 2013, 68:412-418.
3. Verghese J., Ayers E., Barzilai N., et al. Motoric cognitive risk syndrome: Multicenter incidence study. Neurology 2014, 83:2278-2284.
4. Meguro K., Tanaka N., Kasai M., et al. Prevalence of dementia and dementing diseases in the old-old population in Japan: The Kurihara Project. Implications for Long-Term Care Insurance data. Psychogeriatrics 2012, 12:226-234.
5. Shimada H., Tsutsumimoto K., Lee S., et al. Driving continuity in cognitively impaired older drivers. Geriatr Gerontol Int 2015 May 8, [Epub ahead of print].
6. Folstein M.F., Folstein S.E., McHugh P.R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975, 12:189-198.
7. Petersen R.C. Clinical practice. Mild cognitive impairment. N Engl J Med 2011, 364:2227-2234.
8. Yesavage J.A. Geriatric Depression Scale. Psychopharmacol Bull 1988, 24:709-711.
9. van Oijen M., de Jong F.J., Hofman A., et al. Subjective memory complaints, education, and risk of Alzheimer's disease. Alzheimers Dement 2007, 3:92-97.
10. Shimada H., Makizako H., Doi T., et al. Combined prevalence of frailty and mild cognitive impairment in a population of elderly Japanese people. J Am Med Dir Assoc 2013, 14:518-524.
11. Verghese J., LeValley A., Hall C.B., et al. Epidemiology of gait disorders in community-residing older adults. J Am Geriatr Soc 2006, 54:255-261.
12. Barnes D.E., Yaffe K. The projected effect of risk factor reduction on Alzheimer's disease prevalence. Lancet Neurol 2011, 10:819-828.
13. Fujishima M., Kiyohara Y. Incidence and risk factors of dementia in a defined elderly Japanese population:the Hisayama study. Ann N Y Acad Sci 2002, 977:1-8.
14. Chang K.H., Chung C.J., Lin C.L., et al. Increased risk of dementia in patients with osteoporosis: A population-based retrospective cohort analysis. Age (Dordr) 2014, 36:967-975.
15. Hajjar I., Yang F., Sorond F., et al. A novel aging phenotype of slow gait, impaired executive function, and depressive symptoms:relationship to blood pressure and other cardiovascular risks. J Gerontol A Biol Sci Med Sci 2009, 64:994-1001.
16. Wancata J., Alexandrowicz R., Marquart B., et al. The criterion validity of the Geriatric Depression Scale: A systematic review. Acta Psychiatr Scand 2006, 114:398-410.
17. Lamb S.E., Jorstad-Stein E.C., Hauer K., et al. Development of a common outcome data set for fall injury prevention trials: The Prevention of Falls Network Europe consensus. J Am Geriatr Soc 2005, 53:1618-1622.
18. Definition and diagnosis criteria of metabolic syndrome. J Jpn Soc Intern Med 2005, 94:794-809. The Examination Committee for Criteria of Metabolic Syndrome in Japan.
19. Petersen R.C., Roberts R.O., Knopman D.S., et al. Prevalence of mild cognitive impairment is higher in men. The Mayo Clinic Study of Aging. Neurology 2010, 75:889-897.
20. Hanninen T., Hallikainen M., Tuomainen S., et al. Prevalence of mild cognitive impairment: A population-based study in elderly subjects. Acta Neurol Scand 2002, 106:148-154.
21. Nakamura K., Kasai M., Ouchi Y., et al. Apathy is more severe in vascular than amnestic mild cognitive impairment in a community: The Kurihara Project. Psychiatry Clin Neurosci 2013, 67:517-525.
22. Daviglus M.L., Bell C.C., Berrettini W., et al. NIH state-of-the-science conference statement: Preventing Alzheimer's disease and cognitive decline. NIH Consens State Sci Statements 2010, 27:1-30.
23. Forti P., Pisacane N., Rietti E., et al. Metabolic syndrome and risk of dementia in older adults. J Am Geriatr Soc 2010, 58:487-492.
24. Liang K.Y., Mintun M.A., Fagan A.M., et al. Exercise and Alzheimer's disease biomarkers in cognitively normal older adults. Ann Neurol 2010, 68:311-318.
25. Tian Q., Erickson K.I., Simonsick E.M., et al. Physical activity predicts microstructural integrity in memory-related networks in very old adults. J Gerontol A Biol Sci Med Sci 2014, 69:1284-1290.
26. Doi T., Makizako H., Shimada H., et al. Objectively measured physical activity, brain atrophy, and white matter lesions in older adults with mild cognitive impairment. Exp Gerontol 2015, 62:1-6.
27. Makizako H., Liu-Ambrose T., Shimada H., et al. Moderate-intensity physical activity, hippocampal volume, and memory in older adults with mild cognitive impairment. J Gerontol A Biol Sci Med Sci 2015, 70:480-486.
28. Voss M.W., Heo S., Prakash R.S., et al. The influence of aerobic fitness on cerebral white matter integrity and cognitive function in older adults: Results of a one-year exercise intervention. Hum Brain Mapp 2013, 34:2972-2985.
29. Erickson K.I., Voss M.W., Prakash R.S., et al. Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A 2011, 108:3017-3022.
30. Suzuki T., Shimada H., Makizako H., et al. A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment. PLoS One 2013, 8:e61483.
31. Finucane M.M., Stevens G.A., Cowan M.J., et al. National, regional, and global trends in body-mass index since 1980: Systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Lancet 2011, 377:557-567.
32. Biessels G.J., Strachan M.W., Visseren F.L., et al. Dementia and cognitive decline in type 2 diabetes and prediabetic stages:towards targeted interventions. Lancet Diabetes Endocrinol 2014, 2:246-255.
33. Pasquier F., Boulogne A., Leys D., et al. Diabetes mellitus and dementia. Diabetes Metab 2006, 32:403-414.
34. Chang T., Lung F., Yen Y. Depressive symptoms, cognitive impairment, and metabolic syndrome in community-dwelling elderly in Southern Taiwan. Psychogeriatrics 2014 Dec 17, [Epub ahead of print].
35. Doi T., Shimada H., Park H., et al. Cognitive function and falling among older adults with mild cognitive impairment and slow gait. Geriatr Gerontol Int 2015, 15:1073-1078.
36. Seidler R.D., Bernard J.A., Burutolu T.B., et al. Motor control and aging: Links to age-related brain structural, functional, and biochemical effects. Neurosci Biobehav Rev 2010, 34:721-733.
37. Zheng J.J., Delbaere K., Close J.C., et al. Impact of white matter lesions on physical functioning and fall risk in older people: A systematic review. Stroke 2011, 42:2086-2090.
38. Zheng J.J., Lord S.R., Close J.C., et al. Brain white matter hyperintensities, executive dysfunction, instability, and falls in older people: A prospective cohort study. J Gerontol A Biol Sci Med Sci 2012, 67:1085-1091.
39. Iseki K., Hanakawa T., Hashikawa K., et al. Gait disturbance associated with white matter changes: A gait analysis and blood flow study. Neuroimage 2010, 49:1659-1666.
40. Ogama N., Sakurai T., Shimizu A., et al. Regional white matter lesions predict falls in patients with amnestic mild cognitive impairment and Alzheimer's disease. J Am Med Dir Assoc 2014, 15:36-41.
41. Ngandu T., Lehtisalo J., Solomon A., et al. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): A randomised controlled trial. Lancet 2015, 385:2255-2263.