LncRNA Khps1 Regulates Expression of the Proto-oncogene SPHK1 via Triplex-Mediated Changes in Chromatin Structure

Molecular Cell

Volumn 60, Issue 4, 2015, Pages 626-636

  Postepska Igielska, Anna ^a   Giwojna, Alena ^a   Gasri Plotnitsky, Lital ^b   Schmitt, Nina ^a   Dold, Annabelle ^a   Ginsberg, Doron ^b   Grummt, Ingrid ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b BAR ILAN UNIVERSITY   (Israel)

Author keywords

Antisense; Chromatin; E2F1; Khps1; LncRNA; P300; SPHK1; Triplex

Indexed keywords

AFIMOXIFENE; ALPHA AMANITIN; CASPASE 3; COMPLEMENTARY RNA; CURCUMIN; DACTINOMYCIN; DNA FRAGMENT; FLAVOPIRIDOL; HISTONE ACETYLTRANSFERASE PCAF; LONG UNTRANSLATED RNA; LONG UNTRANSLATED RNA KHPS1; RNA POLYMERASE II; SPHINGOSINE KINASE 1; TAMOXIFEN; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG; E2F1 PROTEIN, HUMAN; KHPS1 LONG NONODING RNA, HUMAN; PHOSPHOTRANSFERASE; SPHINGOSINE KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BASE PAIRING; BINDING SITE; CELL CYCLE G1 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL DEATH; CELL GROWTH; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA BINDING; DNA CONTENT; DNA RNA HYBRIDIZATION; ELECTROPHORETIC MOBILITY; EXON; EXOSOME; G1 PHASE CELL CYCLE CHECKPOINT; GEL MOBILITY SHIFT ASSAY; GENE CONTROL; GENE EXPRESSION; GENE LOCUS; GENETIC TRANSCRIPTION; HISTONE ACETYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; INTRON; LUNG CARCINOMA; MOUSE; NONHUMAN; PHOTOACTIVATION; PLASMID; PROMOTER REGION; PROTEIN BINDING; PROTO ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SAOS 2 CELL LINE; TRANSCRIPTION INITIATION; TRANSCRIPTION INITIATION SITE; U2OS CELL LINE; UPREGULATION; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONFORMATION; GENE EXPRESSION REGULATION; GENETICS; HEPG2 CELL LINE; METABOLISM;

APOPTOSIS; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HEP G2 CELLS; HUMANS; NUCLEIC ACID CONFORMATION; P300-CBP TRANSCRIPTION FACTORS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROMOTER REGIONS, GENETIC; RNA, LONG NONCODING;

EID: 84947767904     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.10.001     Document Type: Article

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