-
3
-
-
47249160783
-
Ewing sarcoma: historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the future
-
Ludwig JA. Ewing sarcoma: historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the future. Curr Opin Oncol. 2008; 20:412-8
-
(2008)
Curr Opin Oncol
, vol.20
, pp. 412-418
-
-
Ludwig, J.A.1
-
4
-
-
40949125279
-
Emerging chemotherapeutic strategies and the role of treatment stratification in Ewing sarcoma
-
Seddon BM, Whelan JS. Emerging chemotherapeutic strategies and the role of treatment stratification in Ewing sarcoma. Paediatr drugs. 2008; 10:93-105
-
(2008)
Paediatr drugs
, vol.10
, pp. 93-105
-
-
Seddon, B.M.1
Whelan, J.S.2
-
5
-
-
14944381154
-
P13K/AKT is involved in mediating survival signals that rescue Ewing tumor cells from fibroblast growth factor 2-induced cell death
-
Hotfilder M, Sondermann P, Senß A, et al. P13K/AKT is involved in mediating survival signals that rescue Ewing tumor cells from fibroblast growth factor 2-induced cell death. Br J Cancer. 2005; 92: 705-710
-
(2005)
Br J Cancer
, vol.92
, pp. 705-710
-
-
Hotfilder, M.1
Sondermann, P.2
Senß, A.3
-
6
-
-
84861019279
-
MAP/ERK signaling in osteosarcoma, Ewing sarcoma and chondrosarcomas: Therapeutic implications and future directions
-
Chandhanayingyong C, Kim Y, Staples JR, et al. MAP/ERK signaling in osteosarcoma, Ewing sarcoma and chondrosarcomas: Therapeutic implications and future directions. Sarcoma. 2012; 2012: 404810
-
(2012)
Sarcoma
, vol.2012
-
-
Chandhanayingyong, C.1
Kim, Y.2
Staples, J.R.3
-
7
-
-
49949085240
-
IGF1 is a common target gene of Ewing's sarcoma fusion proteins in mesenchymal progenitor cells
-
Cironi L, Riggi N, Provero P, et al. IGF1 is a common target gene of Ewing's sarcoma fusion proteins in mesenchymal progenitor cells. PLoS One. 2008; 3: e2634
-
(2008)
PLoS One
, vol.3
-
-
Cironi, L.1
Riggi, N.2
Provero, P.3
-
8
-
-
75249095926
-
IGF-1R targeted treatment of sarcoma
-
Toretsky JA, Gorlick R. IGF-1R targeted treatment of sarcoma. Lancet Oncol. 2010; 11:105-6
-
(2010)
Lancet Oncol
, vol.11
, pp. 105-106
-
-
Toretsky, J.A.1
Gorlick, R.2
-
9
-
-
68149156421
-
Simultaneous inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways augment the sensitivity to actinomycin D in Ewing sarcoma
-
Yamamoto T, Ohno T, Wakahara K, et al. Simultaneous inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways augment the sensitivity to actinomycin D in Ewing sarcoma. J Cancer Res Clin Oncol. 2009; 135:1125-36
-
(2009)
J Cancer Res Clin Oncol
, vol.135
, pp. 1125-1136
-
-
Yamamoto, T.1
Ohno, T.2
Wakahara, K.3
-
10
-
-
1642540093
-
Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation
-
Mateo-Lozano S, Tirado OM, Notario V. Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation. Oncogene. 2003; 22:9282-7
-
(2003)
Oncogene
, vol.22
, pp. 9282-9287
-
-
Mateo-Lozano, S.1
Tirado, O.M.2
Notario, V.3
-
11
-
-
84876081696
-
Targeting PI3K/Akt represses Hypoxia inducible factor-1alpha activation and sensitizes rhabdomyosarcoma and Ewing's sarcoma cells for apoptosis
-
Kilic-Eren M, Boylu T, Tabor V. Targeting PI3K/Akt represses Hypoxia inducible factor-1alpha activation and sensitizes rhabdomyosarcoma and Ewing's sarcoma cells for apoptosis. Cancer Cell Int. 2013; 13:36
-
(2013)
Cancer Cell Int
, vol.13
, pp. 36
-
-
Kilic-Eren, M.1
Boylu, T.2
Tabor, V.3
-
12
-
-
84895922568
-
MiR-125b inhibits cell biological progression of Ewing's sarcoma by suppressing the PI3K/Akt signalling pathway
-
Li J, You T, Jing J. MiR-125b inhibits cell biological progression of Ewing's sarcoma by suppressing the PI3K/Akt signalling pathway. Cell Prolif. 2014; 47:152-60
-
(2014)
Cell Prolif
, vol.47
, pp. 152-160
-
-
Li, J.1
You, T.2
Jing, J.3
-
13
-
-
84898723715
-
YAP promotes ovarian cancer cell tumorigenesis and is indicative of a poor prognosis for ovarian cancer patients
-
Xia Y, Chang T, Wang Y, et al. YAP promotes ovarian cancer cell tumorigenesis and is indicative of a poor prognosis for ovarian cancer patients. PLoS One. 2014; 9:e91770
-
(2014)
PLoS One
, vol.9
-
-
Xia, Y.1
Chang, T.2
Wang, Y.3
-
14
-
-
84866274900
-
The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
-
Lamar JM, Stern P, Liu H, et al. The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain. Proc Natl Acad Sci USA. 2012; 109:E2441-50
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. E2441-E2450
-
-
Lamar, J.M.1
Stern, P.2
Liu, H.3
-
15
-
-
45849126780
-
Assessment of muscarinic and nicotinic acetylcholine receptor expression in primitive neuroectodermal tumor/Ewing family of tumor and desmoplastic small round cell tumor: an immunohistochemical and Western blot study of tissue microarray and cell lines
-
Schlauder SM, Steffensen TS, Morgan M, et al. Assessment of muscarinic and nicotinic acetylcholine receptor expression in primitive neuroectodermal tumor/Ewing family of tumor and desmoplastic small round cell tumor: an immunohistochemical and Western blot study of tissue microarray and cell lines. Fetal Pediatr Pathol. 2008; 27:83-97
-
(2008)
Fetal Pediatr Pathol
, vol.27
, pp. 83-97
-
-
Schlauder, S.M.1
Steffensen, T.S.2
Morgan, M.3
-
16
-
-
79955541612
-
Expression of insulin-like growth factor system components in Ewing's sarcoma and their association with survival
-
Scotlandi K, Manara MC, Serra M, et al. Expression of insulin-like growth factor system components in Ewing's sarcoma and their association with survival. Eur J Cancer. 2011; 47:1258-66
-
(2011)
Eur J Cancer
, vol.47
, pp. 1258-1266
-
-
Scotlandi, K.1
Manara, M.C.2
Serra, M.3
-
17
-
-
84883556505
-
Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer
-
Saini KS, Loi S, de Azambuja E, et al. Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer. Cancer Treat Rev. 2013; 39:935-46
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 935-946
-
-
Saini, K.S.1
Loi, S.2
de Azambuja, E.3
-
18
-
-
84856835709
-
Activated growth signaling pathway expression in Ewing sarcoma and clinical outcome
-
Mora J, Rodríguez E, de Torres C, et al. Activated growth signaling pathway expression in Ewing sarcoma and clinical outcome. Pediatr Blood Cancer. 2012; 58:532-8
-
(2012)
Pediatr Blood Cancer
, vol.58
, pp. 532-538
-
-
Mora, J.1
Rodríguez, E.2
de Torres, C.3
-
19
-
-
84890566073
-
Prognostic and therapeutic relevance of the IGF pathway in Ewing's sarcoma patients
-
van de Luijtgaarden AC, Versleijen-Jonkers YM, Roeffen MH, et al. Prognostic and therapeutic relevance of the IGF pathway in Ewing's sarcoma patients. Target Oncol. 2013; 8:253-60
-
(2013)
Target Oncol
, vol.8
, pp. 253-260
-
-
van de Luijtgaarden, A.C.1
Versleijen-Jonkers, Y.M.2
Roeffen, M.H.3
-
20
-
-
84891905701
-
Regulation of YAP through an Akt-dependent process by 3, 3'-diindolylmethane in human colon cancer cells
-
Li XJ, Leem SH, Park MH, et al. Regulation of YAP through an Akt-dependent process by 3, 3'-diindolylmethane in human colon cancer cells. Int J Oncol. 2013; 43:1992-8
-
(2013)
Int J Oncol
, vol.43
, pp. 1992-1998
-
-
Li, X.J.1
Leem, S.H.2
Park, M.H.3
-
21
-
-
79955479018
-
BMI-1 suppresses contact inhibition and stabilizes YAP in Ewing sarcoma
-
Hsu JH, Lawlor ER. BMI-1 suppresses contact inhibition and stabilizes YAP in Ewing sarcoma. Oncogene. 2011; 30:2077-85
-
(2011)
Oncogene
, vol.30
, pp. 2077-2085
-
-
Hsu, J.H.1
Lawlor, E.R.2
-
22
-
-
53049085085
-
BMI-1 promotes Ewing's sarcoma tumorigenicity independent of CDKN2A repression
-
Douglas D, Hsu JH, Hung L, et al. BMI-1 promotes Ewing's sarcoma tumorigenicity independent of CDKN2A repression. Cancer Res. 2008; 68: 6507-15
-
(2008)
Cancer Res
, vol.68
, pp. 6507-6515
-
-
Douglas, D.1
Hsu, J.H.2
Hung, L.3
-
23
-
-
84899924908
-
The dual functions of YAP-1 to promote and inhibit cell growth in human malignancy
-
Wang H, Du YC, Zhou XJ, et al. The dual functions of YAP-1 to promote and inhibit cell growth in human malignancy. Cancer Metastasis Rev. 2014; 33:173-81
-
(2014)
Cancer Metastasis Rev
, vol.33
, pp. 173-181
-
-
Wang, H.1
Du, Y.C.2
Zhou, X.J.3
-
24
-
-
0034648695
-
Interference with the constitutive activation of ERK1 and ERK2 impairs EWS/FLI-1-dependent transformation
-
Silvany RE, Eliazer S, Wolff NC, et al. Interference with the constitutive activation of ERK1 and ERK2 impairs EWS/FLI-1-dependent transformation. Oncogene. 2000; 19:4523-30.
-
(2000)
Oncogene
, vol.19
, pp. 4523-4530
-
-
Silvany, R.E.1
Eliazer, S.2
Wolff, N.C.3
-
25
-
-
79959712087
-
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health
-
Chappell WH, Steelman LS, Long JM, et al. Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health. Oncotarget. 2011; 2:135-64.
-
(2011)
Oncotarget
, vol.2
, pp. 135-164
-
-
Chappell, W.H.1
Steelman, L.S.2
Long, J.M.3
-
26
-
-
84923004530
-
Improving chemoradiation efficacy by PI3-K/AKT inhibition
-
Stegeman H, Span PN, Kaanders JH, et al. Improving chemoradiation efficacy by PI3-K/AKT inhibition. Cancer Treat Rev. 2014; 40:1182-1191.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 1182-1191
-
-
Stegeman, H.1
Span, P.N.2
Kaanders, J.H.3
|