Structure of the RNA Helicase MLE Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling

Molecular Cell

Volumn 60, Issue 3, 2015, Pages 487-499

  Prabu, J Rajan ^a   Müller, Marisa ^b   Thomae, Andreas W ^b   Schüssler, Steffen ^a   Bonneau, Fabien ^a   Becker, Peter B ^b   Conti, Elena ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

DEAH; Dosage compensation; Helicase; MLE; RoX RNA; Structure

Indexed keywords

ADENOSINE TRIPHOSPHATE; RNA; RNA HELICASE; RNA HELICASE MLE; UNCLASSIFIED DRUG; URIDINE; DNA HELICASE; DROSOPHILA PROTEIN; MLE PROTEIN, DROSOPHILA; NONHISTONE PROTEIN; RNA BINDING PROTEIN; ROX2 PROTEIN, DROSOPHILA; TRANSCRIPTION FACTOR;

3' UNTRANSLATED REGION; AMPLICON; ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DELETION MUTANT; DROSOPHILA MELANOGASTER; ELECTROPHORETIC MOBILITY; ENZYME ASSAY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME STRUCTURE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; POINT MUTATION; PROTEIN HYDROLYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBONUCLEASE PROTECTION ASSAY; RNA BINDING; RNA TRANSPORT; X CHROMOSOME; ANIMAL; CHEMISTRY; GENETICS; METABOLISM; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA HELICASES; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; MALE; PROTEIN STRUCTURE, TERTIARY; RNA; RNA HELICASES; RNA-BINDING PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; X CHROMOSOME;

EID: 84947750104     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.10.011     Document Type: Article

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