Experimental infection of a US spike-insertion deletion porcine epidemic diarrhea virus in conventional nursing piglets and cross-protection to the original US PEDV infection

Veterinary Research

Volumn 46, Issue 1, 2015, Pages

  Lin, Chun Ming ^a   Annamalai, Thavamathi ^a   Liu, Xinsheng ^a,b   Gao, Xiang ^a   Lu, Zhongyan ^a   El Tholoth, Mohamed ^a,c   Hu, Hui ^a   Saif, Linda J ^a   Wang, Qiuhong ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b INSTITUTE OF PLANT PROTECTION   (China)

^c Mansoura University   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

CORONAVIRUS SPIKE GLYCOPROTEIN;

ANIMAL; CORONAVIRUS INFECTION; CROSS PROTECTION; DIARRHEA; DNA SEQUENCE; FECES; GENETICS; IMMUNOLOGY; INDEL MUTATION; METABOLISM; PATHOGENICITY; PHYSIOLOGY; PIG; PORCINE EPIDEMIC DIARRHEA VIRUS; SWINE DISEASE; VETERINARY; VIROLOGY; VIRULENCE;

ANIMALS; CORONAVIRUS INFECTIONS; CROSS PROTECTION; DIARRHEA; FECES; INDEL MUTATION; PORCINE EPIDEMIC DIARRHEA VIRUS; SEQUENCE ANALYSIS, DNA; SPIKE GLYCOPROTEIN, CORONAVIRUS; SWINE; SWINE DISEASES; VIRULENCE;

EID: 84947739180     PISSN: 09284249     EISSN: 12979716     Source Type: Journal    
DOI: 10.1186/s13567-015-0278-9     Document Type: Article

References (33)

1. Wood EN (1977) An apparently new syndrome of porcine epidemic diarrhoea. Vet Rec 100:243-244
2. Debouck P, Pensaert M (1980) Experimental infection of pigs with a new porcine enteric coronavirus, CV 777. Am J Vet Res 41:219-223
3. Sun RQ, Cai RJ, Chen YQ, Liang PS, Chen DK, Song CX (2012) Outbreak of porcine epidemic diarrhea in suckling piglets, China. Emerg Infect Dis 18:161-163
4. Sun M, Ma J, Wang Y, Wang M, Song W, Zhang W, Lu C, Yao H (2015) Genomic and epidemiological characteristics provide new insights into the phylogeographical and spatiotemporal spread of porcine epidemic diarrhea virus in Asia. J Clin Microbiol 53:1484-1492
5. Stevenson GW, Hoang H, Schwartz KJ, Burrough ER, Sun D, Madson D, Cooper VL, Pillatzki A, Gauger P, Schmitt BJ, Koster LG, Killian ML, Yoon KJ (2013) Emergence of porcine epidemic diarrhea virus in the United States: clinical signs, lesions, and viral genomic sequences. J Vet Diagn Invest 25:649-654
6. Jung K, Saif LJ (2015) Porcine epidemic diarrhea virus infection: etiology, epidemiology, pathogenesis and immunoprophylaxis. Vet J 204:134-143
7. Alvarez J, Sarradell J, Morrison R, Perez A (2015) Impact of porcine epidemic diarrhea on performance of growing pigs. PLoS One 10:e0120532
8. Vlasova AN, Marthaler D, Wang Q, Culhane MR, Rossow KD, Rovira A, Collins J, Saif LJ (2014) Distinct characteristics and complex evolution of PEDV strains, north America, May 2013-February 2014. Emerg Infect Dis 20:1620-1628
9. Jung K, Wang Q, Scheuer KA, Lu Z, Zhang Y, Saif LJ (2014) Pathology of US porcine epidemic diarrhea virus strain PC21A in gnotobiotic pigs. Emerg Infect Dis 20:662-665
10. Liu X, Lin CM, Annamalai T, Gao X, Lu Z, Esseili MA, Jung K, El-Tholoth M, Saif LJ, Wang Q (2015) Determination of the infectious titer and virulence of an original US porcine epidemic diarrhea virus PC22A strain. Vet Res 46:109
11. Madson DM, Arruda PH, Magstadt DR, Burrough ER, Hoang H, Sun D, Bower LP, Bhandari M, Gauger PC, Stevenson GW, Wilberts BL, Wang C, Zhang J, Yoon KJ. Characterization of porcine epidemic diarrhea virus isolate US/Iowa/18984/2013 infection in 1-day-old cesarean-derived colostrum-deprived piglets. Vet Pathol, in press
12. Jung K, Annamalai T, Lu Z, Saif LJ (2015) Comparative pathogenesis of US porcine epidemic diarrhea virus (PEDV) strain PC21A in conventional 9-day-old nursing piglets vs. 26-day-old weaned pigs. Vet Microbiol 178:31-40
13. Thomas JT, Chen Q, Gauger PC, Giménez-Lirola LG, Sinha A, Harmon KM, Madson DM, Burrough ER, Magstadt DR, Salzbrenner HM, Welch MW, Yoon KJ, Zimmerman JJ, Zhang J (2015) Effect of porcine epidemic diarrhea virus infectious doses on infection outcomes in naïve conventional neonatal and weaned pigs. PLoS One 10:e0139266
14. Madson DM, Magstadt DR, Arruda PH, Hoang H, Sun D, Bower LP, Bhandari M, Burrough ER, Gauger PC, Pillatzki AE, Stevenson GW, Wilberts BL, Brodie J, Harmon KM, Wang C, Main RG, Zhang J, Yoon KJ (2014) Pathogenesis of porcine epidemic diarrhea virus isolate (US/Iowa/18984/2013) in 3-week-old weaned pigs. Vet Microbiol 174:60-68
15. Wang L, Byrum B, Zhang Y (2014) New variant of porcine epidemic diarrhea virus, United States, 2014. Emerg Infect Dis 20:917-919
16. Zhang J, Chen Q, Gauget P, Thomas J, Welch M, Madson D, Magstadt D, Buttough E, Attuda P, Detscheid R (2015) Comparison of the pathogenesis differences of the US PEDV prototype and variant strains in neonatal piglets. In: Proceedings of the 46th annual meeting of the American Association of Swine Veterinarians, Orlando, March 2015, pp 49-51
17. Stadler J, Zoels S, Fux R, Hanke D, Pohlmann A, Blome S, Weissenbock H, Weissenbacher-Lang C, Ritzmann M, Ladinig A (2015) Emergence of porcine epidemic diarrhea virus in southern Germany. BMC Vet Res 11:142
18. Mesquita JR, Hakze-van der Honing R, Almeida A, Lourenco M, van der Poel WH, Nascimento MS (2015) Outbreak of porcine epidemic diarrhea virus in Portugal, 2015. Transbound Emerg Dis 62:586-588
19. Song D, Moon H, Kang B (2015) Porcine epidemic diarrhea: a review of current epidemiology and available vaccines. Clin Exp Vaccine Res 4:166-176
20. Lin CM, Gao X, Oka T, Vlasova AN, Esseili MA, Wang Q, Saif LJ (2015) Antigenic relationships among porcine epidemic diarrhea virus and transmissible gastroenteritis virus strains. J Virol 89:3332-3342
21. Goede D, Murtaugh MP, Nerem J, Yeske P, Rossow K, Morrison R (2014) Previous infection of sows with a "mild" strain of porcine epidemic diarrhea virus confers protection against infection with a "severe" strain. Vet Microbiol 176:161-164
22. Hu H, Jung K, Vlasova AN, Chepngeno J, Lu Z, Wang Q, Saif LJ (2015) Isolation and characterization of porcine deltacoronavirus from pigs with diarrhea in the United States. J Clin Microbiol 53:1537-1548
23. Oka T, Saif LJ, Marthaler D, Esseili MA, Meulia T, Lin CM, Vlasova AN, Jung K, Zhang Y, Wang Q (2014) Cell culture isolation and sequence analysis of genetically diverse US porcine epidemic diarrhea virus strains including a novel strain with a large deletion in the spike gene. Vet Microbiol 173:258-269
24. Lin CM, Jeng CR, Hsiao SH, Liu JP, Chang CC, Chiou MT, Tsai YC, Chia MY, Pang VF (2011) Immunopathological characterization of porcine circovirus type 2 infection-associated follicular changes in inguinal lymph nodes using high-throughput tissue microarray. Vet Microbiol 149:72-84
25. Shibata I, Tsuda T, Mori M, Ono M, Sueyoshi M, Uruno K (2000) Isolation of porcine epidemic diarrhea virus in porcine cell cultures and experimental infection of pigs of different ages. Vet Microbiol 72:173-182
26. Wolf J, Žáková E, Groeneveld E (2008) Within-litter variation of birth weight in hyperprolific Czech large white sows and its relation to litter size traits, stillborn piglets and losses until weaning. Livestock Sci 115:195-205
27. Preidis GA, Saulnier DM, Blutt SE, Mistretta TA, Riehle KP, Major AM, Venable SF, Barrish JP, Finegold MJ, Petrosino JF, Guerrant RL, Conner ME, Versalovic J (2012) Host response to probiotics determined by nutritional status of rotavirus-infected neonatal mice. J Pediatr Gastroenterol Nutr 55:299-307
28. Kim O, Chae C (2003) Experimental infection of piglets with a korean strain of porcine epidemic diarrhoea virus. J Comp Pathol 129:55-60
29. Moon HW (1971) Epithelial cell migration in the alimentary mucosa of the suckling pig. Proc Soc Exp Biol Med 137:151-154
30. Weingartl HM, Derbyshire JB (1993) Binding of porcine transmissible gastroenteritis virus by enterocytes from newborn and weaned piglets. Vet Microbiol 35:23-32
31. Song D, Park B (2012) Porcine epidemic diarrhoea virus: a comprehensive review of molecular epidemiology, diagnosis, and vaccines. Virus Genes 44:167-175
32. La Bonnardiere C, Laude H (1981) High interferon titer in newborn pig intestine during experimentally induced viral enteritis. Infect Immun 32:28-31
33. Jung K, Eyerly B, Annamalai T, Lu Z, Saif LJ (2015) Structural alteration of tight and adherens junctions in villous and crypt epithelium of the small and large intestine of conventional nursing piglets infected with porcine epidemic diarrhea virus. Vet Microbiol 177:373-378