Induction and testing of hypoxia in cell culture

Journal of Visualized Experiments

Volumn , Issue 54, 2011, Pages

  Wu, Danli ^a   Yotnda, Patricia ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80355132642     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/2899     Document Type: Article

References (9)

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3. Hockel, M., et al. Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix. Radiother Oncol. 26 (1), 45-50 (1993).
4. Semenza, G.L. HIF-1 and human disease: one highly involved factor. Genes Dev. 14 (16), 1983-1991 (2000).
5. Semenza, G.L. Hypoxia-inducible factor 1: master regulator of O2 homeostasis. Curr Opin Genet Dev. 8 (5), 588-594 (1998).
6. Tatum, J.L., et al. Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy. Int J Radiat Biol. 82 (10), 699-757 (2006).
7. Brahimi-Horn, M.C. & Pouyssegur, J. HIF at a glance. J Cell Sci. 122 (Pt 8), 1055-1057 (2009).
8. Piret, J.P., Mottet, D., Raes, M., & Michiels, C. CoCl2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2. Ann N Y Acad Sci. 973, 443-447 (2002).
9. Emerling, B.M., Weinberg, F., Liu, J.L., Mak, T.W., & Chandel, N.S. PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a). Proc Natl Acad Sci U S A. 105 (7), 2622-2627 (2008).