Rosette nanotubes alter IgE-mediated degranulation in the rat basophilic leukemia (RBL)-2H3 cell line

Toxicological Sciences

Volumn 148, Issue 1, 2015, Pages 108-120

  Ede, James D ^a   Ortega, Van A ^a   Boyle, David ^a   Beingessner, Rachel L ^b   Hemraz, Usha D ^b   Fenniri, Hicham ^c   Stafford, James L ^a   Goss, Greg G ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c Northeastern University   (United States)

Author keywords

Degranulation; Inflammation; Nanotoxicology; Rosette nanotubes; Self assembly

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; IMMUNOGLOBULIN E; LYSINE; NANOTUBE; ROSETTE NANOTUBE; UNCLASSIFIED DRUG; BIOMATERIAL; DRUG CARRIER; FLUORESCENT DYE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DEGRANULATION; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INTERNALIZATION; INTRACELLULAR SIGNALING; LEUKEMIA CELL; MAST CELL LEUKEMIA; NANOTOXICOLOGY; NONHUMAN; RAT; ROSETTE FORMATION; SYNTHESIS; ZETA POTENTIAL; ABSORPTION; ANIMAL; BASOPHIL; BASOPHIL DEGRANULATION TEST; CELL SURVIVAL; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECTS; HEK293 CELL LINE; HUMAN; HYDROGEN BOND; IMMUNOLOGY; METABOLISM; REPORTER GENE; SIGNAL TRANSDUCTION; SURFACE PROPERTY; TUMOR CELL LINE; UPREGULATION;

ABSORPTION, PHYSIOLOGICAL; ANIMALS; BASOPHIL DEGRANULATION TEST; BASOPHILS; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; GENES, REPORTER; HEK293 CELLS; HUMANS; HYDROGEN BONDING; IMMUNOGLOBULIN E; LYSINE; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, CONFOCAL; NANOTUBES; RATS; SURFACE PROPERTIES; UP-REGULATION;

EID: 84947707210     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv166     Document Type: Article

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