How microgravity affects the biology of living systems

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Bizzarri, Mariano ^a   Monici, Monica ^b   Loon, Jack J W A Van ^c  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; BIOLOGICAL FUNCTIONS; CELL ADHESION; CELL FUNCTION; CELL INTERACTION; CELL PROLIFERATION; CELL STRUCTURE; CYTOSKELETON; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; GRAVITATIONAL STRESS; HOMEOSTASIS; HUMAN; MICROENVIRONMENT; MICROGRAVITY; NONHUMAN; ORGANISMS; REVIEW; SIGNAL TRANSDUCTION; SPACE FLIGHT; TISSUE STRUCTURE; WEIGHTLESSNESS; AEROSPACE MEDICINE; ANIMAL; BIOPHYSICS; CYTOLOGY; MEDICAL RESEARCH; TUMOR MICROENVIRONMENT;

AEROSPACE MEDICINE; ANIMALS; BIOMEDICAL RESEARCH; BIOPHYSICAL PHENOMENA; CELL BIOLOGY; CELLULAR MICROENVIRONMENT; HUMANS; WEIGHTLESSNESS;

EID: 84947649593     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/863075     Document Type: Review

References (22)

1. P. O. Montgomery Jr. , J. E. Cook, R. C. Reynolds et al. , "The response of single human cells to zero gravity, " In Vitro, vol. 14, no. 2, pp. 165-173, 1978.
2. M. G. Tairbekov, G. P. Parfyonov, E. Y. Shepelev, and F. V. Sushkov, "Experimental and theoretical analysis of the influence of gravity at the cellular level: a review, " Advances in Space Research, vol. 3, no. 9, pp. 153-158, 1983.
3. J. J. W. van Loon, "The gravity environment in Space experiments, " in Biology in Space and Life on Earth. Effects of Spaceflight on Biological Systems, E. Brinckmann, Ed. , pp. 17-32, Wiley-VCH, 2007.
4. T. G. Hammond and J. M. Hammond, "Optimized suspension culture: the rotating-wall vessel, " American Journal of Physiology-Renal Physiology, vol. 281, no. 1, pp. F12-F25, 2001.
5. P. Todd, "Gravity-dependent phenomena at the scale of the single cell, " ASGSB Bulletin, vol. 2, pp. 95-113, 1989.
6. L. E. Freed, R. Langer, I. Martin, N. R. Pellis, and G. Vunjak-Novakovic, "Tissue engineering of cartilage in space, " Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 25, pp. 13885-13890, 1997.
7. J. Klein-Nulend, R. G. Bacabac, J. P. Veldhuijzen, and J. J. W. A. Van Loon, "Microgravity and bone cell mechanosensitivity, " Advances in Space Research, vol. 32, no. 8, pp. 1551-1559, 2003.
8. S. J. Pardo, M. J. Patel, M. C. Sykes et al. , "Simulatedmicrogravity using the Random PositioningMachine inhibits differentiation and alters gene expression profiles of 2T3 preosteoblasts, " American Journal of Physiology-Cell Physiology, vol. 288, no. 6, pp. C1211-C1221, 2005.
9. M. Monici, F. Fusi, M. Paglierani et al. , "Modeled gravitational unloading triggers differentiation and apoptosis in preosteoclastic cells, " Journal of Cellular Biochemistry, vol. 98, no. 1, pp. 65-80, 2006.
10. G. Nicolis and I. Prigogine, "Introduction, " in Self-Organization in Nonequilibrium Systems: From Dissipative Structures to Order Through Fluctuations, JohnWiley & Sons, New York, NY, USA, 1977.
11. P. J. Stiles and D. F. Fletcher, "The effect of gravity on the rate of a simple liquid-state reaction in a small, unstirred cylindrical vessel, " Physical Chemistry Chemical Physics, vol. 3, no. 9, pp. 1617-1621, 2001.
12. C. Papaseit, N. Pochon, and J. Tabony, "Microtubule selforganization is gravity-dependent, " Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 15, pp. 8364-8368, 2000.
13. M. Bizzarri and A. Giuliani, "Represeenting cancer cell trajectories in a phase-space diagram: switching cellular states by biological phase transitions, " in Applied Statistics for Network Biology: Methods in Systems Biology, M. Dehmer, F. Emmert-Streib, A. Graber, and A. Salvador, Eds. , pp. 377-403, Wiley, New York, NY, USA, 2011.
14. M. Bizzarri, A. Cucina, A. Palombo, and M. Grazia Masiello, "Gravity sensing by cells:Mechanisms and theoretical grounds, " Rendiconti Lincei, vol. 25, no. 1, pp. 29-38, 2014.
15. M. L. Lewis, "Thecytoskeleton in spaceflown cells: an overview, " Gravitational and Space Biology Bulletin, vol. 17, pp. 1-11, 2004.
16. D. Vorselen, W. H. Roos, F. C. MacKintosh, G. J. L. Wuite, and J. J. W. A. van Loon, "The role of the cytoskeleton in sensing changes in gravity by nonspecialized cells, " FASEB Journal, vol. 28, no. 2, pp. 536-547, 2014.
17. D. Grimm, M. Wehland, J. Pietsch et al. , "Growing tissues in real and simulated microgravity: new methods for tissue engineering, " Tissue Engineering Part B: Reviews, vol. 20, no. 6, pp. 555-566, 2014.
18. G. R. Souza, J. R. Molina, R. M. Raphael et al. , "Threedimensional tissue culture based on magnetic cell levitation, " Nature Nanotechnology, vol. 5, no. 4, pp. 291-296, 2010.
19. D. Schmitt, "Workshop purpose and structure, " The FASEB Journal, vol. 13, supplement S1, no. 9001, 1999.
20. M. Bizzarri, A. Pasqualato, A. Cucina, and V. Pasta, "Physical forces and non linear dynamics mould fractal cell shape. Quantitative morphological parameters and cell phenotype, " Histology and Histopathology, vol. 28, no. 2, pp. 155-174, 2013.
21. M. Monici and J. van Loon, Cell Mechanochemistry. Biological Systems and Factors Inducing Mechanical Stress, Such as Light, Pressure and Gravity, Trivandrum Research Signpost/ Transword Research Network, 2010.
22. J. L. Becker and G. R. Souza, "Using space-based investigations to informcancer research on Earth, " Nature Reviews Cancer, vol. 13, no. 5, pp. 315-327, 2013.