-
1
-
-
0025304539
-
Rheumatoid arthritis. Pathophysiology and implications for therapy
-
PID: 2271017
-
Harris ED Jr (1990) Rheumatoid arthritis. Pathophysiology and implications for therapy. N Engl J Med 322:1277–1289
-
(1990)
N Engl J Med
, vol.322
, pp. 1277-1289
-
-
Harris, E.D.1
-
2
-
-
31544455037
-
Genome scan meta-analysis of rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BD28Xmslyqtg%3D%3D
-
Choi SJ, Rho YH, Ji JD, Song GG, Lee YH (2006) Genome scan meta-analysis of rheumatoid arthritis. Rheumatology (Oxford) 45:166–170
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 166-170
-
-
Choi, S.J.1
Rho, Y.H.2
Ji, J.D.3
Song, G.G.4
Lee, Y.H.5
-
3
-
-
61849086101
-
Janus kinases in immune cell signaling
-
COI: 1:CAS:528:DC%2BD1MXhsFGls7vJ, PID: 19290934
-
Ghoreschi K, Laurence A, O’Shea JJ (2009) Janus kinases in immune cell signaling. Immunol Rev 228:273–287
-
(2009)
Immunol Rev
, vol.228
, pp. 273-287
-
-
Ghoreschi, K.1
Laurence, A.2
O’Shea, J.J.3
-
4
-
-
0242332186
-
Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor
-
COI: 1:CAS:528:DC%2BD3sXos1Cmtrg%3D, PID: 14593182
-
Changelian PS, Flanagan ME, Ball DJ, Kent CR, Magnuson KS, Martin WH, Rizzuti BJ, Sawyer PS, Perry BD, Brissette WH, McCurdy SP, Kudlacz EM, Conklyn MJ, Elliott EA, Koslov ER, Fisher MB, Strelevitz TJ, Yoon K, Whipple DA, Sun J, Munchhof MJ, Doty JL, Casavant JM, Blumenkopf TA, Hines M, Brown MF, Lillie BM, Subramanyam C, Shang-Poa C, Milici AJ, Beckius GE, Moyer JD, Su C, Woodworth TG, Gaweco AS, Beals CR, Littman BH, Fisher DA, Smith JF, Zagouras P, Magna HA, Saltarelli MJ, Johnson KS, Nelms LF, Des Etages SG, Hayes LS, Kawabata TT, Finco-Kent D, Baker DL, Larson M, Si MS, Paniagua R, Higgins J, Holm B, Reitz B, Zhou YJ, Morris RE, O’Shea JJ, Borie DC (2003) Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor. Science 302:875–878
-
(2003)
Science
, vol.302
, pp. 875-878
-
-
Changelian, P.S.1
Flanagan, M.E.2
Ball, D.J.3
Kent, C.R.4
Magnuson, K.S.5
Martin, W.H.6
Rizzuti, B.J.7
Sawyer, P.S.8
Perry, B.D.9
Brissette, W.H.10
McCurdy, S.P.11
Kudlacz, E.M.12
Conklyn, M.J.13
Elliott, E.A.14
Koslov, E.R.15
Fisher, M.B.16
Strelevitz, T.J.17
Yoon, K.18
Whipple, D.A.19
Sun, J.20
Munchhof, M.J.21
Doty, J.L.22
Casavant, J.M.23
Blumenkopf, T.A.24
Hines, M.25
Brown, M.F.26
Lillie, B.M.27
Subramanyam, C.28
Shang-Poa, C.29
Milici, A.J.30
Beckius, G.E.31
Moyer, J.D.32
Su, C.33
Woodworth, T.G.34
Gaweco, A.S.35
Beals, C.R.36
Littman, B.H.37
Fisher, D.A.38
Smith, J.F.39
Zagouras, P.40
Magna, H.A.41
Saltarelli, M.J.42
Johnson, K.S.43
Nelms, L.F.44
Des Etages, S.G.45
Hayes, L.S.46
Kawabata, T.T.47
Finco-Kent, D.48
Baker, D.L.49
Larson, M.50
Si, M.S.51
Paniagua, R.52
Higgins, J.53
Holm, B.54
Reitz, B.55
Zhou, Y.J.56
Morris, R.E.57
O’Shea, J.J.58
Borie, D.C.59
more..
-
5
-
-
77954385114
-
Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6
-
COI: 1:CAS:528:DC%2BC3cXos1ylt7g%3D, PID: 20478313
-
Chrencik JE, Patny A, Leung IK, Korniski B, Emmons TL, Hall T, Weinberg RA, Gormley JA, Williams JM, Day JE, Hirsch JL, Kiefer JR, Leone JW, Fischer HD, Sommers CD, Huang HC, Jacobsen EJ, Tenbrink RE, Tomasselli AG, Benson TE (2010) Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J Mol Biol 400:413–433
-
(2010)
J Mol Biol
, vol.400
, pp. 413-433
-
-
Chrencik, J.E.1
Patny, A.2
Leung, I.K.3
Korniski, B.4
Emmons, T.L.5
Hall, T.6
Weinberg, R.A.7
Gormley, J.A.8
Williams, J.M.9
Day, J.E.10
Hirsch, J.L.11
Kiefer, J.R.12
Leone, J.W.13
Fischer, H.D.14
Sommers, C.D.15
Huang, H.C.16
Jacobsen, E.J.17
Tenbrink, R.E.18
Tomasselli, A.G.19
Benson, T.E.20
more..
-
6
-
-
77955375143
-
Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis
-
Meyer DM, Jesson MI, Li X, Elrick MM, Funckes-Shippy CL, Warner JD, Gross CJ, Dowty ME, Ramaiah SK, Hirsch JL, Saabye MJ, Barks JL, Kishore N, Morris DL (2010) Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis. J Inflamm 7:41
-
(2010)
J Inflamm
, vol.7
, pp. 41
-
-
Meyer, D.M.1
Jesson, M.I.2
Li, X.3
Elrick, M.M.4
Funckes-Shippy, C.L.5
Warner, J.D.6
Gross, C.J.7
Dowty, M.E.8
Ramaiah, S.K.9
Hirsch, J.L.10
Saabye, M.J.11
Barks, J.L.12
Kishore, N.13
Morris, D.L.14
-
7
-
-
84902593564
-
Tofacitinib versus methotrexate in rheumatoid arthritis
-
PID: 24941177
-
Lee EB, Fleischmann R, Hall S, Wilkinson B, Bradley JD, Gruben D, Koncz T, Krishnaswami S, Wallenstein GV, Zang C, Zwillich SH, van Vollenhoven RF, Investigators OS (2014) Tofacitinib versus methotrexate in rheumatoid arthritis. N Engl J Med 370:2377–2386
-
(2014)
N Engl J Med
, vol.370
, pp. 2377-2386
-
-
Lee, E.B.1
Fleischmann, R.2
Hall, S.3
Wilkinson, B.4
Bradley, J.D.5
Gruben, D.6
Koncz, T.7
Krishnaswami, S.8
Wallenstein, G.V.9
Zang, C.10
Zwillich, S.H.11
van Vollenhoven, R.F.12
Investigators, O.S.13
-
8
-
-
84882266430
-
Tofacitinib in combination with nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: a randomized trial
-
PID: 24026258
-
Kremer J, Li ZG, Hall S, Fleischmann R, Genovese M, Martin-Mola E, Isaacs JD, Gruben D, Wallenstein G, Krishnaswami S, Zwillich SH, Koncz T, Riese R, Bradley J (2013) Tofacitinib in combination with nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: a randomized trial. Ann Intern Med 159:253–261
-
(2013)
Ann Intern Med
, vol.159
, pp. 253-261
-
-
Kremer, J.1
Li, Z.G.2
Hall, S.3
Fleischmann, R.4
Genovese, M.5
Martin-Mola, E.6
Isaacs, J.D.7
Gruben, D.8
Wallenstein, G.9
Krishnaswami, S.10
Zwillich, S.H.11
Koncz, T.12
Riese, R.13
Bradley, J.14
-
9
-
-
84874402383
-
Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: twelve-month data from a twenty-four-month phase III randomized radiographic study
-
PID: 23348607
-
van der Heijde D, Tanaka Y, Fleischmann R, Keystone E, Kremer J, Zerbini C, Cardiel MH, Cohen S, Nash P, Song YW, Tegzova D, Wyman BT, Gruben D, Benda B, Wallenstein G, Krishnaswami S, Zwillich SH, Bradley JD, Connell CA, Investigators OS (2013) Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: twelve-month data from a twenty-four-month phase III randomized radiographic study. Arthritis Rheum 65:559–570
-
(2013)
Arthritis Rheum
, vol.65
, pp. 559-570
-
-
van der Heijde, D.1
Tanaka, Y.2
Fleischmann, R.3
Keystone, E.4
Kremer, J.5
Zerbini, C.6
Cardiel, M.H.7
Cohen, S.8
Nash, P.9
Song, Y.W.10
Tegzova, D.11
Wyman, B.T.12
Gruben, D.13
Benda, B.14
Wallenstein, G.15
Krishnaswami, S.16
Zwillich, S.H.17
Bradley, J.D.18
Connell, C.A.19
Investigators, O.S.20
more..
-
10
-
-
84878104859
-
Tofacitinib for rheumatoid arthritis—Authors’ reply
-
PID: 23706795
-
Burmester GR, Benda B, Gruben D, Bradley J, Mebus C (2013) Tofacitinib for rheumatoid arthritis—Authors’ reply. Lancet 381:1812–1813
-
(2013)
Lancet
, vol.381
, pp. 1812-1813
-
-
Burmester, G.R.1
Benda, B.2
Gruben, D.3
Bradley, J.4
Mebus, C.5
-
11
-
-
84864703156
-
Tofacitinib or adalimumab versus placebo in rheumatoid arthritis
-
PID: 22873531
-
van Vollenhoven RF, Fleischmann R, Cohen S, Lee EB, Garcia Meijide JA, Wagner S, Forejtova S, Zwillich SH, Gruben D, Koncz T, Wallenstein GV, Krishnaswami S, Bradley JD, Wilkinson B, Investigators OS (2012) Tofacitinib or adalimumab versus placebo in rheumatoid arthritis. N Engl J Med 367:508–519
-
(2012)
N Engl J Med
, vol.367
, pp. 508-519
-
-
van Vollenhoven, R.F.1
Fleischmann, R.2
Cohen, S.3
Lee, E.B.4
Garcia Meijide, J.A.5
Wagner, S.6
Forejtova, S.7
Zwillich, S.H.8
Gruben, D.9
Koncz, T.10
Wallenstein, G.V.11
Krishnaswami, S.12
Bradley, J.D.13
Wilkinson, B.14
Investigators, O.S.15
-
12
-
-
84864716411
-
Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC38Xht1SisrbI, PID: 22873530
-
Fleischmann R, Kremer J, Cush J, Schulze-Koops H, Connell CA, Bradley JD, Gruben D, Wallenstein GV, Zwillich SH, Kanik KS, Investigators OS (2012) Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis. N Engl J Med 367:495–507
-
(2012)
N Engl J Med
, vol.367
, pp. 495-507
-
-
Fleischmann, R.1
Kremer, J.2
Cush, J.3
Schulze-Koops, H.4
Connell, C.A.5
Bradley, J.D.6
Gruben, D.7
Wallenstein, G.V.8
Zwillich, S.H.9
Kanik, K.S.10
Investigators, O.S.11
-
13
-
-
84866156845
-
A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone
-
COI: 1:CAS:528:DC%2BC38XmvVygt78%3D, PID: 22006202
-
Kremer JM, Cohen S, Wilkinson BE, Connell CA, French JL, Gomez-Reino J, Gruben D, Kanik KS, Krishnaswami S, Pascual-Ramos V, Wallenstein G, Zwillich SH (2012) A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone. Arthritis Rheum 64:970–981
-
(2012)
Arthritis Rheum
, vol.64
, pp. 970-981
-
-
Kremer, J.M.1
Cohen, S.2
Wilkinson, B.E.3
Connell, C.A.4
French, J.L.5
Gomez-Reino, J.6
Gruben, D.7
Kanik, K.S.8
Krishnaswami, S.9
Pascual-Ramos, V.10
Wallenstein, G.11
Zwillich, S.H.12
-
14
-
-
84857761516
-
Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs
-
COI: 1:CAS:528:DC%2BC38XivVGjurs%3D, PID: 21952978
-
Fleischmann R, Cutolo M, Genovese MC, Lee EB, Kanik KS, Sadis S, Connell CA, Gruben D, Krishnaswami S, Wallenstein G, Wilkinson BE, Zwillich SH (2012) Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs. Arthritis Rheum 64:617–629
-
(2012)
Arthritis Rheum
, vol.64
, pp. 617-629
-
-
Fleischmann, R.1
Cutolo, M.2
Genovese, M.C.3
Lee, E.B.4
Kanik, K.S.5
Sadis, S.6
Connell, C.A.7
Gruben, D.8
Krishnaswami, S.9
Wallenstein, G.10
Wilkinson, B.E.11
Zwillich, S.H.12
-
15
-
-
84860388892
-
Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate
-
COI: 1:CAS:528:DC%2BC3MXhtFKjtb%2FE
-
Tanaka Y, Suzuki M, Nakamura H, Toyoizumi S, Zwillich SH, Tofacitinib Study I (2011) Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate. Arthritis Care Res 63:1150–1158
-
(2011)
Arthritis Care Res
, vol.63
, pp. 1150-1158
-
-
Tanaka, Y.1
Suzuki, M.2
Nakamura, H.3
Toyoizumi, S.4
Zwillich, S.H.5
Tofacitinib Study, I.6
-
16
-
-
67650093218
-
The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo
-
COI: 1:CAS:528:DC%2BD1MXptlKktLg%3D, PID: 19565475
-
Kremer JM, Bloom BJ, Breedveld FC, Coombs JH, Fletcher MP, Gruben D, Krishnaswami S, Burgos-Vargas R, Wilkinson B, Zerbini CA (2009) The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo. Arthritis Rheum 60:1895–1905
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1895-1905
-
-
Kremer, J.M.1
Bloom, B.J.2
Breedveld, F.C.3
Coombs, J.H.4
Fletcher, M.P.5
Gruben, D.6
Krishnaswami, S.7
Burgos-Vargas, R.8
Wilkinson, B.9
Zerbini, C.A.10
-
17
-
-
84907157319
-
Efficacy and safety of tofacitinib for active rheumatoid arthritis with an inadequate response to methotrexate or disease-modifying antirheumatic drugs: a meta-analysis of randomized controlled trials
-
COI: 1:CAS:528:DC%2BC2cXitVGmtb3E, PID: 25228842
-
Song GG, Bae S-C, Lee YH (2014) Efficacy and safety of tofacitinib for active rheumatoid arthritis with an inadequate response to methotrexate or disease-modifying antirheumatic drugs: a meta-analysis of randomized controlled trials. Korean J Intern Med 29:656–663
-
(2014)
Korean J Intern Med
, vol.29
, pp. 656-663
-
-
Song, G.G.1
Bae, S.-C.2
Lee, Y.H.3
-
18
-
-
80052462502
-
Associations between vitamin D receptor polymorphisms and susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis
-
COI: 1:CAS:528:DC%2BC3MXnsVChtbs%3D, PID: 21110115
-
Lee YH, Bae SC, Choi SJ, Ji JD, Song GG (2011) Associations between vitamin D receptor polymorphisms and susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis. Mol Biol Rep 38:3643–3651
-
(2011)
Mol Biol Rep
, vol.38
, pp. 3643-3651
-
-
Lee, Y.H.1
Bae, S.C.2
Choi, S.J.3
Ji, J.D.4
Song, G.G.5
-
19
-
-
34250183488
-
PADI4 polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis
-
COI: 1:CAS:528:DC%2BD2sXmtlGkt7c%3D, PID: 17265154
-
Lee YH, Rho YH, Choi SJ, Ji JD, Song GG (2007) PADI4 polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis. Rheumatol Int 27:827–833
-
(2007)
Rheumatol Int
, vol.27
, pp. 827-833
-
-
Lee, Y.H.1
Rho, Y.H.2
Choi, S.J.3
Ji, J.D.4
Song, G.G.5
-
20
-
-
84897120085
-
Network meta-analysis for comparing treatment effects of multiple interventions: an introduction
-
PID: 24691560
-
Catalá-López F, Tobías A, Cameron C, Moher D, Hutton B (2014) Network meta-analysis for comparing treatment effects of multiple interventions: an introduction. Rheumatol Int 34:1489–1496
-
(2014)
Rheumatol Int
, vol.34
, pp. 1489-1496
-
-
Catalá-López, F.1
Tobías, A.2
Cameron, C.3
Moher, D.4
Hutton, B.5
-
21
-
-
26944454062
-
Simultaneous comparison of multiple treatments: combining direct and indirect evidence
-
PID: 16223826
-
Caldwell DM, Ades A, Higgins J (2005) Simultaneous comparison of multiple treatments: combining direct and indirect evidence. BMJ 331:897
-
(2005)
BMJ
, vol.331
, pp. 897
-
-
Caldwell, D.M.1
Ades, A.2
Higgins, J.3
-
22
-
-
84859001212
-
The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
-
PID: 22008217
-
Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, Savović J, Schulz KF, Weeks L, Sterne JA (2011) The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ 343:d5928
-
(2011)
BMJ
, vol.343
, pp. d5928
-
-
Higgins, J.P.1
Altman, D.G.2
Gøtzsche, P.C.3
Jüni, P.4
Moher, D.5
Oxman, A.D.6
Savović, J.7
Schulz, K.F.8
Weeks, L.9
Sterne, J.A.10
-
23
-
-
69149107165
-
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
-
PID: 19622511
-
Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151:264–269
-
(2009)
Ann Intern Med
, vol.151
, pp. 264-269
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
-
24
-
-
84914165160
-
A Microsoft-Excel-based tool for running and critically appraising network meta-analyses—an overview and application of NetMetaXL
-
PID: 25267416
-
Brown S, Hutton B, Clifford T, Coyle D, Grima D, Wells G, Cameron C (2014) A Microsoft-Excel-based tool for running and critically appraising network meta-analyses—an overview and application of NetMetaXL. Syst Rev 3:110
-
(2014)
Syst Rev
, vol.3
, pp. 110
-
-
Brown, S.1
Hutton, B.2
Clifford, T.3
Coyle, D.4
Grima, D.5
Wells, G.6
Cameron, C.7
-
25
-
-
78650509651
-
Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial
-
PID: 20688472
-
Salanti G, Ades A, Ioannidis JP (2011) Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. J Clin Epidemiol 64:163–171
-
(2011)
J Clin Epidemiol
, vol.64
, pp. 163-171
-
-
Salanti, G.1
Ades, A.2
Ioannidis, J.P.3
-
26
-
-
84879754189
-
Evidence synthesis for decision making 4 inconsistency in networks of evidence based on randomized controlled trials
-
PID: 23804508
-
Dias S, Welton NJ, Sutton AJ, Caldwell DM, Lu G, Ades A (2013) Evidence synthesis for decision making 4 inconsistency in networks of evidence based on randomized controlled trials. Med Decis Making 33:641–656
-
(2013)
Med Decis Making
, vol.33
, pp. 641-656
-
-
Dias, S.1
Welton, N.J.2
Sutton, A.J.3
Caldwell, D.M.4
Lu, G.5
Ades, A.6
-
27
-
-
84875625927
-
Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies
-
COI: 1:STN:280:DC%2BC2Mbitlyiuw%3D%3D, PID: 26062084
-
Higgins J, Jackson D, Barrett J, Lu G, Ades A, White I (2012) Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies. Res Synth Methods 3:98–110
-
(2012)
Res Synth Methods
, vol.3
, pp. 98-110
-
-
Higgins, J.1
Jackson, D.2
Barrett, J.3
Lu, G.4
Ades, A.5
White, I.6
-
28
-
-
84887334981
-
Automating network meta-analysis. Research synthesis
-
Valkenhoef G, Lu G, Brock B, Hillege H, Ades A, Welton NJ (2012) Automating network meta-analysis. Research synthesis. Methods 3:285–299
-
(2012)
Methods
, vol.3
, pp. 285-299
-
-
Valkenhoef, G.1
Lu, G.2
Brock, B.3
Hillege, H.4
Ades, A.5
Welton, N.J.6
-
29
-
-
84872132785
-
FDA approves tofacitinib for rheumatoid arthritis
-
Traynor K (2012) FDA approves tofacitinib for rheumatoid arthritis. Am J Health Syst Pharm 69:2120
-
(2012)
Am J Health Syst Pharm
, vol.69
, pp. 2120
-
-
Traynor, K.1
-
30
-
-
23944510494
-
Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines
-
COI: 1:CAS:528:DC%2BD2MXovV2rtr4%3D, PID: 16134056
-
Herman S, Zurgil N, Deutsch M (2005) Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines. Inflamm Res 54:273–280
-
(2005)
Inflamm Res
, vol.54
, pp. 273-280
-
-
Herman, S.1
Zurgil, N.2
Deutsch, M.3
-
31
-
-
84904733767
-
Systematic review of tofacitinib: a new drug for the management of rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC2cXhtF2ksb%2FI, PID: 25047498
-
Kaur K, Kalra S, Kaushal S (2014) Systematic review of tofacitinib: a new drug for the management of rheumatoid arthritis. Clin Ther 36:1074–1086
-
(2014)
Clin Ther
, vol.36
, pp. 1074-1086
-
-
Kaur, K.1
Kalra, S.2
Kaushal, S.3
-
32
-
-
84906100884
-
Efficacy and safety of tofacitinib for treatment of rheumatoid arthritis
-
PID: 25232526
-
Lundquist LM, Cole SW, Sikes ML (2014) Efficacy and safety of tofacitinib for treatment of rheumatoid arthritis. World J Orthop 5:504
-
(2014)
World J Orthop
, vol.5
, pp. 504
-
-
Lundquist, L.M.1
Cole, S.W.2
Sikes, M.L.3
-
33
-
-
84882266430
-
Tofacitinib in combination with nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: a randomized trial
-
PID: 24026258
-
Kremer J, Li Z-G, Hall S, Fleischmann R, Genovese M, Martin-Mola E, Isaacs JD, Gruben D, Wallenstein G, Krishnaswami S (2013) Tofacitinib in combination with nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: a randomized trial. Ann Intern Med 159:253–261
-
(2013)
Ann Intern Med
, vol.159
, pp. 253-261
-
-
Kremer, J.1
Li, Z.-G.2
Hall, S.3
Fleischmann, R.4
Genovese, M.5
Martin-Mola, E.6
Isaacs, J.D.7
Gruben, D.8
Wallenstein, G.9
Krishnaswami, S.10
-
34
-
-
84864703156
-
Tofacitinib or adalimumab versus placebo in rheumatoid arthritis
-
PID: 22873531
-
van Vollenhoven RF, Fleischmann R, Cohen S, Lee EB, García Meijide JA, Wagner S, Forejtova S, Zwillich SH, Gruben D, Koncz T (2012) Tofacitinib or adalimumab versus placebo in rheumatoid arthritis. N Engl J Med 367:508–519
-
(2012)
N Engl J Med
, vol.367
, pp. 508-519
-
-
van Vollenhoven, R.F.1
Fleischmann, R.2
Cohen, S.3
Lee, E.B.4
García Meijide, J.A.5
Wagner, S.6
Forejtova, S.7
Zwillich, S.H.8
Gruben, D.9
Koncz, T.10
-
35
-
-
84861043518
-
Risk of tuberculosis reactivation with tofacitinib (CP-690550)
-
COI: 1:CAS:528:DC%2BC38Xnt1amtL0%3D, PID: 22474037
-
Maiga M, Lun S, Guo H, Winglee K, Ammerman NC, Bishai WR (2012) Risk of tuberculosis reactivation with tofacitinib (CP-690550). J Infect Dis 205:1705–1708
-
(2012)
J Infect Dis
, vol.205
, pp. 1705-1708
-
-
Maiga, M.1
Lun, S.2
Guo, H.3
Winglee, K.4
Ammerman, N.C.5
Bishai, W.R.6
-
36
-
-
84873707288
-
Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial
-
COI: 1:CAS:528:DC%2BC3sXkvFOqsw%3D%3D, PID: 23294500
-
Burmester GR, Blanco R, Charles-Schoeman C, Wollenhaupt J, Zerbini C, Benda B, Gruben D, Wallenstein G, Krishnaswami S, Zwillich SH (2013) Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial. Lancet 381:451–460
-
(2013)
Lancet
, vol.381
, pp. 451-460
-
-
Burmester, G.R.1
Blanco, R.2
Charles-Schoeman, C.3
Wollenhaupt, J.4
Zerbini, C.5
Benda, B.6
Gruben, D.7
Wallenstein, G.8
Krishnaswami, S.9
Zwillich, S.H.10
-
37
-
-
84857761516
-
Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs
-
COI: 1:CAS:528:DC%2BC38XivVGjurs%3D, PID: 21952978
-
Fleischmann R, Cutolo M, Genovese MC, Lee EB, Kanik KS, Sadis S, Connell CA, Gruben D, Krishnaswami S, Wallenstein G (2012) Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs. Arthritis Rheum 64:617–629
-
(2012)
Arthritis Rheum
, vol.64
, pp. 617-629
-
-
Fleischmann, R.1
Cutolo, M.2
Genovese, M.C.3
Lee, E.B.4
Kanik, K.S.5
Sadis, S.6
Connell, C.A.7
Gruben, D.8
Krishnaswami, S.9
Wallenstein, G.10
-
38
-
-
84885491518
-
Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis
-
COI: 1:CAS:528:DC%2BC3sXhvFWltrzE, PID: 24139404
-
He Y, Wong AY, Chan EW, Lau WC, Man KK, Chui CS, Worsley AJ, Wong IC (2013) Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis. BMC Musculoskelet Disord 14:298
-
(2013)
BMC Musculoskelet Disord
, vol.14
, pp. 298
-
-
He, Y.1
Wong, A.Y.2
Chan, E.W.3
Lau, W.C.4
Man, K.K.5
Chui, C.S.6
Worsley, A.J.7
Wong, I.C.8
-
39
-
-
84885311733
-
The effectiveness of tofacitinib, a novel Janus kinase inhibitor, in the treatment of rheumatoid arthritis: a systematic review and meta-analysis
-
PID: 23877486
-
Kawalec P, Mikrut A, Wiśniewska N, Pilc A (2013) The effectiveness of tofacitinib, a novel Janus kinase inhibitor, in the treatment of rheumatoid arthritis: a systematic review and meta-analysis. Clin Rheumatol 32:1415–1424
-
(2013)
Clin Rheumatol
, vol.32
, pp. 1415-1424
-
-
Kawalec, P.1
Mikrut, A.2
Wiśniewska, N.3
Pilc, A.4
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