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Volumn 35, Issue 12, 2015, Pages 1965-1974

Comparative efficacy and safety of tofacitinib, with or without methotrexate, in patients with active rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials

Author keywords

Efficacy; Network meta analysis; Rheumatoid arthritis; Safety; Tofacitinib

Indexed keywords

ADALIMUMAB; METHOTREXATE; PLACEBO; TOFACITINIB; ANTIRHEUMATIC AGENT; PIPERIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE;

EID: 84947616388     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-015-3291-4     Document Type: Article
Times cited : (18)

References (39)
  • 1
    • 0025304539 scopus 로고
    • Rheumatoid arthritis. Pathophysiology and implications for therapy
    • PID: 2271017
    • Harris ED Jr (1990) Rheumatoid arthritis. Pathophysiology and implications for therapy. N Engl J Med 322:1277–1289
    • (1990) N Engl J Med , vol.322 , pp. 1277-1289
    • Harris, E.D.1
  • 2
  • 3
    • 61849086101 scopus 로고    scopus 로고
    • Janus kinases in immune cell signaling
    • COI: 1:CAS:528:DC%2BD1MXhsFGls7vJ, PID: 19290934
    • Ghoreschi K, Laurence A, O’Shea JJ (2009) Janus kinases in immune cell signaling. Immunol Rev 228:273–287
    • (2009) Immunol Rev , vol.228 , pp. 273-287
    • Ghoreschi, K.1    Laurence, A.2    O’Shea, J.J.3
  • 10
    • 84878104859 scopus 로고    scopus 로고
    • Tofacitinib for rheumatoid arthritis—Authors’ reply
    • PID: 23706795
    • Burmester GR, Benda B, Gruben D, Bradley J, Mebus C (2013) Tofacitinib for rheumatoid arthritis—Authors’ reply. Lancet 381:1812–1813
    • (2013) Lancet , vol.381 , pp. 1812-1813
    • Burmester, G.R.1    Benda, B.2    Gruben, D.3    Bradley, J.4    Mebus, C.5
  • 13
    • 84866156845 scopus 로고    scopus 로고
    • A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone
    • COI: 1:CAS:528:DC%2BC38XmvVygt78%3D, PID: 22006202
    • Kremer JM, Cohen S, Wilkinson BE, Connell CA, French JL, Gomez-Reino J, Gruben D, Kanik KS, Krishnaswami S, Pascual-Ramos V, Wallenstein G, Zwillich SH (2012) A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone. Arthritis Rheum 64:970–981
    • (2012) Arthritis Rheum , vol.64 , pp. 970-981
    • Kremer, J.M.1    Cohen, S.2    Wilkinson, B.E.3    Connell, C.A.4    French, J.L.5    Gomez-Reino, J.6    Gruben, D.7    Kanik, K.S.8    Krishnaswami, S.9    Pascual-Ramos, V.10    Wallenstein, G.11    Zwillich, S.H.12
  • 14
    • 84857761516 scopus 로고    scopus 로고
    • Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs
    • COI: 1:CAS:528:DC%2BC38XivVGjurs%3D, PID: 21952978
    • Fleischmann R, Cutolo M, Genovese MC, Lee EB, Kanik KS, Sadis S, Connell CA, Gruben D, Krishnaswami S, Wallenstein G, Wilkinson BE, Zwillich SH (2012) Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs. Arthritis Rheum 64:617–629
    • (2012) Arthritis Rheum , vol.64 , pp. 617-629
    • Fleischmann, R.1    Cutolo, M.2    Genovese, M.C.3    Lee, E.B.4    Kanik, K.S.5    Sadis, S.6    Connell, C.A.7    Gruben, D.8    Krishnaswami, S.9    Wallenstein, G.10    Wilkinson, B.E.11    Zwillich, S.H.12
  • 15
    • 84860388892 scopus 로고    scopus 로고
    • Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate
    • COI: 1:CAS:528:DC%2BC3MXhtFKjtb%2FE
    • Tanaka Y, Suzuki M, Nakamura H, Toyoizumi S, Zwillich SH, Tofacitinib Study I (2011) Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate. Arthritis Care Res 63:1150–1158
    • (2011) Arthritis Care Res , vol.63 , pp. 1150-1158
    • Tanaka, Y.1    Suzuki, M.2    Nakamura, H.3    Toyoizumi, S.4    Zwillich, S.H.5    Tofacitinib Study, I.6
  • 16
    • 67650093218 scopus 로고    scopus 로고
    • The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo
    • COI: 1:CAS:528:DC%2BD1MXptlKktLg%3D, PID: 19565475
    • Kremer JM, Bloom BJ, Breedveld FC, Coombs JH, Fletcher MP, Gruben D, Krishnaswami S, Burgos-Vargas R, Wilkinson B, Zerbini CA (2009) The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo. Arthritis Rheum 60:1895–1905
    • (2009) Arthritis Rheum , vol.60 , pp. 1895-1905
    • Kremer, J.M.1    Bloom, B.J.2    Breedveld, F.C.3    Coombs, J.H.4    Fletcher, M.P.5    Gruben, D.6    Krishnaswami, S.7    Burgos-Vargas, R.8    Wilkinson, B.9    Zerbini, C.A.10
  • 17
    • 84907157319 scopus 로고    scopus 로고
    • Efficacy and safety of tofacitinib for active rheumatoid arthritis with an inadequate response to methotrexate or disease-modifying antirheumatic drugs: a meta-analysis of randomized controlled trials
    • COI: 1:CAS:528:DC%2BC2cXitVGmtb3E, PID: 25228842
    • Song GG, Bae S-C, Lee YH (2014) Efficacy and safety of tofacitinib for active rheumatoid arthritis with an inadequate response to methotrexate or disease-modifying antirheumatic drugs: a meta-analysis of randomized controlled trials. Korean J Intern Med 29:656–663
    • (2014) Korean J Intern Med , vol.29 , pp. 656-663
    • Song, G.G.1    Bae, S.-C.2    Lee, Y.H.3
  • 18
    • 80052462502 scopus 로고    scopus 로고
    • Associations between vitamin D receptor polymorphisms and susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis
    • COI: 1:CAS:528:DC%2BC3MXnsVChtbs%3D, PID: 21110115
    • Lee YH, Bae SC, Choi SJ, Ji JD, Song GG (2011) Associations between vitamin D receptor polymorphisms and susceptibility to rheumatoid arthritis and systemic lupus erythematosus: a meta-analysis. Mol Biol Rep 38:3643–3651
    • (2011) Mol Biol Rep , vol.38 , pp. 3643-3651
    • Lee, Y.H.1    Bae, S.C.2    Choi, S.J.3    Ji, J.D.4    Song, G.G.5
  • 19
    • 34250183488 scopus 로고    scopus 로고
    • PADI4 polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis
    • COI: 1:CAS:528:DC%2BD2sXmtlGkt7c%3D, PID: 17265154
    • Lee YH, Rho YH, Choi SJ, Ji JD, Song GG (2007) PADI4 polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis. Rheumatol Int 27:827–833
    • (2007) Rheumatol Int , vol.27 , pp. 827-833
    • Lee, Y.H.1    Rho, Y.H.2    Choi, S.J.3    Ji, J.D.4    Song, G.G.5
  • 20
    • 84897120085 scopus 로고    scopus 로고
    • Network meta-analysis for comparing treatment effects of multiple interventions: an introduction
    • PID: 24691560
    • Catalá-López F, Tobías A, Cameron C, Moher D, Hutton B (2014) Network meta-analysis for comparing treatment effects of multiple interventions: an introduction. Rheumatol Int 34:1489–1496
    • (2014) Rheumatol Int , vol.34 , pp. 1489-1496
    • Catalá-López, F.1    Tobías, A.2    Cameron, C.3    Moher, D.4    Hutton, B.5
  • 21
    • 26944454062 scopus 로고    scopus 로고
    • Simultaneous comparison of multiple treatments: combining direct and indirect evidence
    • PID: 16223826
    • Caldwell DM, Ades A, Higgins J (2005) Simultaneous comparison of multiple treatments: combining direct and indirect evidence. BMJ 331:897
    • (2005) BMJ , vol.331 , pp. 897
    • Caldwell, D.M.1    Ades, A.2    Higgins, J.3
  • 23
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • PID: 19622511
    • Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151:264–269
    • (2009) Ann Intern Med , vol.151 , pp. 264-269
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 24
    • 84914165160 scopus 로고    scopus 로고
    • A Microsoft-Excel-based tool for running and critically appraising network meta-analyses—an overview and application of NetMetaXL
    • PID: 25267416
    • Brown S, Hutton B, Clifford T, Coyle D, Grima D, Wells G, Cameron C (2014) A Microsoft-Excel-based tool for running and critically appraising network meta-analyses—an overview and application of NetMetaXL. Syst Rev 3:110
    • (2014) Syst Rev , vol.3 , pp. 110
    • Brown, S.1    Hutton, B.2    Clifford, T.3    Coyle, D.4    Grima, D.5    Wells, G.6    Cameron, C.7
  • 25
    • 78650509651 scopus 로고    scopus 로고
    • Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial
    • PID: 20688472
    • Salanti G, Ades A, Ioannidis JP (2011) Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. J Clin Epidemiol 64:163–171
    • (2011) J Clin Epidemiol , vol.64 , pp. 163-171
    • Salanti, G.1    Ades, A.2    Ioannidis, J.P.3
  • 26
    • 84879754189 scopus 로고    scopus 로고
    • Evidence synthesis for decision making 4 inconsistency in networks of evidence based on randomized controlled trials
    • PID: 23804508
    • Dias S, Welton NJ, Sutton AJ, Caldwell DM, Lu G, Ades A (2013) Evidence synthesis for decision making 4 inconsistency in networks of evidence based on randomized controlled trials. Med Decis Making 33:641–656
    • (2013) Med Decis Making , vol.33 , pp. 641-656
    • Dias, S.1    Welton, N.J.2    Sutton, A.J.3    Caldwell, D.M.4    Lu, G.5    Ades, A.6
  • 27
    • 84875625927 scopus 로고    scopus 로고
    • Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies
    • COI: 1:STN:280:DC%2BC2Mbitlyiuw%3D%3D, PID: 26062084
    • Higgins J, Jackson D, Barrett J, Lu G, Ades A, White I (2012) Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies. Res Synth Methods 3:98–110
    • (2012) Res Synth Methods , vol.3 , pp. 98-110
    • Higgins, J.1    Jackson, D.2    Barrett, J.3    Lu, G.4    Ades, A.5    White, I.6
  • 29
    • 84872132785 scopus 로고    scopus 로고
    • FDA approves tofacitinib for rheumatoid arthritis
    • Traynor K (2012) FDA approves tofacitinib for rheumatoid arthritis. Am J Health Syst Pharm 69:2120
    • (2012) Am J Health Syst Pharm , vol.69 , pp. 2120
    • Traynor, K.1
  • 30
    • 23944510494 scopus 로고    scopus 로고
    • Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines
    • COI: 1:CAS:528:DC%2BD2MXovV2rtr4%3D, PID: 16134056
    • Herman S, Zurgil N, Deutsch M (2005) Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines. Inflamm Res 54:273–280
    • (2005) Inflamm Res , vol.54 , pp. 273-280
    • Herman, S.1    Zurgil, N.2    Deutsch, M.3
  • 31
    • 84904733767 scopus 로고    scopus 로고
    • Systematic review of tofacitinib: a new drug for the management of rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC2cXhtF2ksb%2FI, PID: 25047498
    • Kaur K, Kalra S, Kaushal S (2014) Systematic review of tofacitinib: a new drug for the management of rheumatoid arthritis. Clin Ther 36:1074–1086
    • (2014) Clin Ther , vol.36 , pp. 1074-1086
    • Kaur, K.1    Kalra, S.2    Kaushal, S.3
  • 32
    • 84906100884 scopus 로고    scopus 로고
    • Efficacy and safety of tofacitinib for treatment of rheumatoid arthritis
    • PID: 25232526
    • Lundquist LM, Cole SW, Sikes ML (2014) Efficacy and safety of tofacitinib for treatment of rheumatoid arthritis. World J Orthop 5:504
    • (2014) World J Orthop , vol.5 , pp. 504
    • Lundquist, L.M.1    Cole, S.W.2    Sikes, M.L.3
  • 35
    • 84861043518 scopus 로고    scopus 로고
    • Risk of tuberculosis reactivation with tofacitinib (CP-690550)
    • COI: 1:CAS:528:DC%2BC38Xnt1amtL0%3D, PID: 22474037
    • Maiga M, Lun S, Guo H, Winglee K, Ammerman NC, Bishai WR (2012) Risk of tuberculosis reactivation with tofacitinib (CP-690550). J Infect Dis 205:1705–1708
    • (2012) J Infect Dis , vol.205 , pp. 1705-1708
    • Maiga, M.1    Lun, S.2    Guo, H.3    Winglee, K.4    Ammerman, N.C.5    Bishai, W.R.6
  • 36
    • 84873707288 scopus 로고    scopus 로고
    • Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial
    • COI: 1:CAS:528:DC%2BC3sXkvFOqsw%3D%3D, PID: 23294500
    • Burmester GR, Blanco R, Charles-Schoeman C, Wollenhaupt J, Zerbini C, Benda B, Gruben D, Wallenstein G, Krishnaswami S, Zwillich SH (2013) Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial. Lancet 381:451–460
    • (2013) Lancet , vol.381 , pp. 451-460
    • Burmester, G.R.1    Blanco, R.2    Charles-Schoeman, C.3    Wollenhaupt, J.4    Zerbini, C.5    Benda, B.6    Gruben, D.7    Wallenstein, G.8    Krishnaswami, S.9    Zwillich, S.H.10
  • 37
    • 84857761516 scopus 로고    scopus 로고
    • Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs
    • COI: 1:CAS:528:DC%2BC38XivVGjurs%3D, PID: 21952978
    • Fleischmann R, Cutolo M, Genovese MC, Lee EB, Kanik KS, Sadis S, Connell CA, Gruben D, Krishnaswami S, Wallenstein G (2012) Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs. Arthritis Rheum 64:617–629
    • (2012) Arthritis Rheum , vol.64 , pp. 617-629
    • Fleischmann, R.1    Cutolo, M.2    Genovese, M.C.3    Lee, E.B.4    Kanik, K.S.5    Sadis, S.6    Connell, C.A.7    Gruben, D.8    Krishnaswami, S.9    Wallenstein, G.10
  • 38
    • 84885491518 scopus 로고    scopus 로고
    • Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis
    • COI: 1:CAS:528:DC%2BC3sXhvFWltrzE, PID: 24139404
    • He Y, Wong AY, Chan EW, Lau WC, Man KK, Chui CS, Worsley AJ, Wong IC (2013) Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis. BMC Musculoskelet Disord 14:298
    • (2013) BMC Musculoskelet Disord , vol.14 , pp. 298
    • He, Y.1    Wong, A.Y.2    Chan, E.W.3    Lau, W.C.4    Man, K.K.5    Chui, C.S.6    Worsley, A.J.7    Wong, I.C.8
  • 39
    • 84885311733 scopus 로고    scopus 로고
    • The effectiveness of tofacitinib, a novel Janus kinase inhibitor, in the treatment of rheumatoid arthritis: a systematic review and meta-analysis
    • PID: 23877486
    • Kawalec P, Mikrut A, Wiśniewska N, Pilc A (2013) The effectiveness of tofacitinib, a novel Janus kinase inhibitor, in the treatment of rheumatoid arthritis: a systematic review and meta-analysis. Clin Rheumatol 32:1415–1424
    • (2013) Clin Rheumatol , vol.32 , pp. 1415-1424
    • Kawalec, P.1    Mikrut, A.2    Wiśniewska, N.3    Pilc, A.4


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