IL-17 receptor A and adenosine deaminase 2 deficiency in siblings with recurrent infections and chronic inflammation

Journal of Allergy and Clinical Immunology

Volumn 137, Issue 4, 2016, Pages 1189-1196.e2

  Fellmann, Florence ^a   Angelini, Federica ^a   Wassenberg, Jacqueline ^a   Perreau, Matthieu ^a   Arenas Ramirez, Natalia ^b   Simon, Gregoire ^a   Boyman, Onur ^b   Demaria, Olivier ^a   Christen Zaech, Stephanie ^a   Hohl, Daniel ^a   Belfiore, Marco ^a   Von Scheven Gete, Annette ^a   Gilliet, Michel ^a   Bochud, Pierre Yves ^a   Perrin, Yannick ^a   Beck Popovic, Maya ^a   Bart, Pierre Alexandre ^a   Beckmann, Jacques S ^a,c   Martinet, Danielle ^a   Hofer, Michaël ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

Adenosine deaminase 2; CECR1; chronic inflammation; chronic mucocutaneous candidiasis; IL17RA; immunodeficiency; vasculitis; whole genome analyses

Indexed keywords

ADENOSINE DEAMINASE; ADENOSINE DEAMINASE 2; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; GAMMA INTERFERON; IMMUNOGLOBULIN G; INFLIXIMAB; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 17 RECEPTOR A; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; MESSENGER RNA; PREDNISONE; SERUM AMYLOID A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CECR1 PROTEIN, HUMAN; IL17RA PROTEIN, HUMAN; SIGNAL PEPTIDE;

ADOLESCENT; ADULT; ANTIBIOTIC THERAPY; ARTICLE; BRONCHIECTASIS; CANDIDA ALBICANS; CASE REPORT; CD4+ T LYMPHOCYTE; CHRONIC INFLAMMATION; COMPARATIVE GENOMIC HYBRIDIZATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEVELOPMENTAL DISORDER; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHEMA NODOSUM; ERYTHROCYTE SEDIMENTATION RATE; FAILURE TO THRIVE; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GRANULOCYTE; HOMOZYGOSITY; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; INFECTION SENSITIVITY; LUNG ABSCESS; LUNG INFECTION; LUNG LAVAGE; LYMPHOCYTE COUNT; MUCOCUTANEOUS CANDIDIASIS; NEUTROPENIA; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PSORIASIS; RADIOIMMUNOASSAY; RECURRENT INFECTION; RETINA VASCULITIS; SHWACHMAN SYNDROME; SIGNAL TRANSDUCTION; SKIN DEFECT; SMALL VESSEL VASCULITIS; SPLENOMEGALY; STAPHYLOCOCCAL SKIN INFECTION; TH17 CELL; UPREGULATION; VAGINA CANDIDIASIS; VEIN OCCLUSION; YOUNG ADULT; CHILD; CHRONIC DISEASE; COMPLICATION; DEFICIENCY; FATALITY; GENETICS; IMMUNOLOGY; INFLAMMATION; PRESCHOOL CHILD; SIBLING; VASCULITIS;

ADENOSINE DEAMINASE; ADOLESCENT; CANDIDIASIS, CHRONIC MUCOCUTANEOUS; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; COMPARATIVE GENOMIC HYBRIDIZATION; FATAL OUTCOME; FEMALE; HUMANS; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; RECEPTORS, INTERLEUKIN-17; SEQUENCE DELETION; SIBLINGS; VASCULITIS;

EID: 84947559428     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.07.053     Document Type: Article

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