Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians

Immunology and Cell Biology

Volumn 94, Issue 4, 2016, Pages 367-377

  Clemens, E Bridie ^a   Grant, Emma J ^a   Wang, Zhongfang ^a   Gras, Stephanie ^b   Tipping, Peta ^c   Rossjohn, Jamie ^b,d   Miller, Adrian ^e   Tong, Steven Y C ^c   Kedzierska, Katherine ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^d CARDIFF UNIVERSITY   (United Kingdom)

^e GRIFFITH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; GAMMA INTERFERON; GLUTAMIC ACID; HLA A ANTIGEN; HLA A2 ANTIGEN; HLA B13 ANTIGEN; HLA B56 ANTIGEN; HLA DPB1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DRB1 ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; EPITOPE; HLA ANTIGEN; IFITM3 PROTEIN, HUMAN; INFLUENZA VACCINE; LYMPHOCYTE ANTIGEN RECEPTOR; M1 PROTEIN, INFLUENZA A VIRUS; MATRIX PROTEIN; MEMBRANE PROTEIN; RNA BINDING PROTEIN;

ALLELE; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; GENETICS; GENOTYPE; HUMAN; IMMUNE SYSTEM; INDIGENOUS AUSTRALIAN; INFLUENZA; ADULT; CELL CULTURE; FEMALE; HISTOCOMPATIBILITY TEST; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; OCEANIC ANCESTRY GROUP; PHYSIOLOGY; RISK;

ADULT; ALLELES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; EPITOPES, T-LYMPHOCYTE; FEMALE; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; INFLUENZA VACCINES; INFLUENZA, HUMAN; INTERFERON-GAMMA; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; MALE; MEMBRANE PROTEINS; MIDDLE AGED; OCEANIC ANCESTRY GROUP; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RISK; RNA-BINDING PROTEINS; TUMOR NECROSIS FACTOR-ALPHA; VIRAL MATRIX PROTEINS;

EID: 84947554970     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2015.93     Document Type: Article

References (33)

1. Briscoe G. Disease Health & Healing - Aspects of Indigenous Health in WA & Queensland, 1900-1940. PhD thesis, 1996.
2. Flint SM, Davis JS, Su JY, Oliver-Landry EP, Rogers BA, Goldstein A et al. Disproportionate impact of pandemic (H1N1) 2009 influenza on Indigenous people in the Top End of Australia's Northern Territory. Med J Aust 2010; 192: 617-622.
3. Investigators AI, Webb SA, Pettila V, Seppelt I, Bellomo R, Bailey M et al. Critical care services and 2009 H1N1 influenza in Australia and New Zealand. N Engl J Med 2009; 361: 1925-1934.
4. La Ruche G, Tarantola A, Barboza P, Vaillant L, Gueguen J, Gastellu-Etchegorry M et al. The 2009 pandemic H1N1 influenza and indigenous populations of the Americas and the Pacific. Eur Surveill 2009; 14: 19366.
5. Kumar A, Zarychanski R, Pinto R, Cook DJ, Marshall J, Lacroix J et al. Critically ill patients with 2009 influenza A(H1N1) infection in Canada. JAMA 2009; 302: 1872-1879.
6. Zhang YH, Zhao Y, Li N, Peng YC, Giannoulatou E, Jin RH et al. Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals. Nat Commun 2013; 4: 1418.
7. Wang Z, Zhang A, Wan Y, Liu X, Qiu C, Xi X et al. Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection. Proc Natl Acad Sci USA 2014; 111: 769-774.
8. Sridhar S, Begom S, Bermingham A, Hoschler K, Adamson W, Carman W et al. Cellular immune correlates of protection against symptomatic pandemic influenza. Nat Med 2013; 19: 1305-1312.
9. Wang Z, Wan Y, Qiu C, Quinones-Parra S, Zhu Z, Loh L et al. Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8(+) T cells. Nat Commun 2015; 6: 6833.
10. Hayward AC, Wang L, Goonetilleke N, Fragaszy EB, Bermingham A, Copas A et al. Natural T Cell-mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study. Am J Respir Crit Care Med 2015; 191: 1422-1431.
11. Quinones-Parra S, Grant E, Loh L, Nguyen TH, Campbell KA, Tong SY et al. Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities. Proc Natl Acad Sci USA 2014; 111: 1049-1054.
12. Hertz T, Oshansky CM, Roddam PL, DeVincenzo JP, Caniza MA, Jojic N et al. HLA targeting efficiency correlates with human T-cell response magnitude and with mortality from influenza A infection. Proc Natl Acad Sci USA 2013; 110: 13492-13497.
13. Ahmed R, Oldstone MB, Palese P. Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic. Nat Immunol 2007; 8: 1188-1193.
14. Lester S, Cassidy S, Humphreys I, Bennett G, Hurley CK, Boettcher B et al. Evolution in HLA-DRB1 and major histocompatibility complex class II haplotypes of Australian aborigines. Definition of a new DRB1 allele and distribution of DRB1 gene frequencies. Hum Immunol 1995; 42: 154-160.
15. Lienert K, McCluskey J, Bennett G, Fowler C, Russ G. HLA class I variation in Australian aborigines: characterization of allele B∗1521. Tissue Antigens 1995; 45: 12-17.
16. Gao X, Lester S, Matheson B, Boettcher B, McCluskey J. Three newly identified A∗24 alleles: A∗2406, A∗2413 and A∗2414. Tissue Antigens 1997; 50: 192-196.
17. Lin L, Tokunaga K, Tanaka H, Nakajima F, Imanishi T, Kashiwase K et al. Further molecular diversity in the HLA-B15 group. Tissue Antigens 1996; 47: 265-274.
18. Lee LY, Ha do LA, Simmons C, de Jong MD, Chau NV, Schumacher R et al. Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals. J Clin Invest 2008; 118: 3478-3490.
19. van de Sandt CE, Kreijtz JH, de Mutsert G, Geelhoed-Mieras MM, Hillaire ML, Vogelzangvan Trierum SE et al. Human cytotoxic T lymphocytes directed to seasonal influenza A viruses cross-react with the newly emerging H7N9 virus. J Virol 2014; 88: 1684-1693.
20. Gras S, Kedzierski L, Valkenburg SA, Laurie K, Liu YC, Denholm JT et al. Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses. Proc Natl Acad Sci USA 2010; 107: 12599-12604.
21. Nguyen TH, Rowntree LC, Pellicci DG, Bird NL, Handel A, Kjer-Nielsen L et al. Recognition of distinct cross-reactive virus-specific CD8+ T cells reveals a unique TCR signature in a clinical setting. J Immunol 2014; 192: 5039-5049.
22. Messaoudi I, Guevara Patino JA, Dyall R, LeMaoult J, Nikolich-Zugich J. Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense. Science 2002; 298: 1797-1800.
23. Price DA, West SM, Betts MR, Ruff LE, Brenchley JM, Ambrozak DR et al. T cell receptor recognition motifs govern immune escape patterns in acute SIV infection. Immunity 2004; 21: 793-803.
24. Valkenburg SA, Day EB, Swan NG, Croom HA, Carbone FR, Doherty PC et al. Fixing an irrelevant TCR alpha chain reveals the importance of TCR beta diversity for optimal TCR alpha beta pairing and function of virus-specific CD8+ T cells. Eur J Immunol 2010; 40: 2470-2481.
25. Valkenburg SA, Gras S, Guillonneau C, La Gruta NL, Thomas PG, Purcell AW et al. Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold. PLoS Pathog 2010; 6: e1001039.
26. Lehner PJ, Wang EC, Moss PA, Williams S, Platt K, Friedman SM et al. Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment. J Exp Med 1995; 181: 79-91.
27. Moss PA, Moots RJ, Rosenberg WM, Rowland-Jones SJ, Bodmer HC, McMichael AJ et al. Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide. Proc Natl Acad Sci USA 1991; 88: 8987-8990.
28. Wang GC, Dash P, McCullers JA, Doherty PC, Thomas PG. T cell receptor alphabeta diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection. Sci Transl Med 2012; 4: 128ra142.
29. Quinones-Parra S, Loh L, Brown LE, Kedzierska K, Valkenburg SA. Universal immunity to influenza must outwit immune evasion. Front Microbiol 2014; 5: 285.
30. Everitt AR, Clare S, Pertel T, John SP, Wash RS, Smith SE et al. IFITM3 restricts the morbidity and mortality associated with influenza. Nature 2012; 484: 519-523.
31. Valkenburg SA, Rutigliano JA, Ellebedy AH, Doherty PC, Thomas PG, Kedzierska K. Immunity to seasonal and pandemic influenza A viruses. Microbe Infect 2011; 13: 489-501.
32. Illing PT, Vivian JP, Dudek NL, Kostenko L, Chen Z, Bharadwaj M et al. Immune selfreactivity triggered by drug-modified HLA-peptide repertoire. Nature 2012; 486: 554-558.
33. DeLano WL. The PyMOL Molecular Graphics System. Available at http://www. pymol.org 2002.