메뉴 건너뛰기




Volumn 10, Issue 9, 2015, Pages

Detection of an abundant plant-based small RNA in healthy consumers

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE 2 PROTEIN; CHAMOMILE; MICRORNA; MICRORNA 16; MICRORNA 2911; PLANT RNA; UNCLASSIFIED DRUG;

EID: 84947483887     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0137516     Document Type: Article
Times cited : (82)

References (42)
  • 1
    • 84896719020 scopus 로고    scopus 로고
    • Transfer and functional consequences of dietary microRNAs in vertebrates: Concepts in search of corroboration: Negative results challenge the hypothesis that dietary xenomiRs cross the gut and regulate genes in ingesting vertebrates, but important questions persist
    • 24436255 PubMed Central PMCID: PMC4109825
    • Witwer KW, Hirschi KD. Transfer and functional consequences of dietary microRNAs in vertebrates: concepts in search of corroboration: negative results challenge the hypothesis that dietary xenomiRs cross the gut and regulate genes in ingesting vertebrates, but important questions persist. Bioessays. 2014; 36(4):394-406. doi: 10.1002/bies.201300150 PMID: 24436255; PubMed Central PMCID: PMC4109825.
    • (2014) Bioessays , vol.36 , Issue.4 , pp. 394-406
    • Witwer, K.W.1    Hirschi, K.D.2
  • 2
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • 19167326
    • Bartel DP. MicroRNAs: Target Recognition and Regulatory Functions. Cell. 2009; 136(2):215-33. doi: 10.1016/j.cell.2009.01.002 PMID: 19167326
    • (2009) Cell , vol.136 , Issue.2 , pp. 215-233
    • Bartel, D.P.1
  • 3
    • 84894472195 scopus 로고    scopus 로고
    • Evolutionary history of plant microRNAs
    • 24405820
    • Taylor RS, Tarver JE, Hiscock SJ, Donoghue PC. Evolutionary history of plant microRNAs. Trends Plant Sci. 2014; 19(3):175-82. doi: 10.1016/j.tplants.2013.11.008 PMID: 24405820.
    • (2014) Trends Plant Sci. , vol.19 , Issue.3 , pp. 175-182
    • Taylor, R.S.1    Tarver, J.E.2    Hiscock, S.J.3    Donoghue, P.C.4
  • 4
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • 15685193 Epub 2005/02/03
    • Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005; 433(7027):769-73. Epub 2005/02/03. doi: 10.1038/nature03315 PMID: 15685193.
    • (2005) Nature , vol.433 , Issue.7027 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3    Grimson, A.4    Schelter, J.M.5    Castle, J.6
  • 5
    • 59249089695 scopus 로고    scopus 로고
    • Shedding microvesicles: Artefacts no more
    • 19144520
    • Cocucci E, Racchetti G, Meldolesi J. Shedding microvesicles: artefacts no more. Trends in cell biology. 2009; 19(2):43-51. doi: 10.1016/j.tcb.2008.11.003 PMID: 19144520
    • (2009) Trends in Cell Biology , vol.19 , Issue.2 , pp. 43-51
    • Cocucci, E.1    Racchetti, G.2    Meldolesi, J.3
  • 6
    • 79953202200 scopus 로고    scopus 로고
    • Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
    • 21383194 PubMed Central PMCID: PMC3064324
    • Arroyo JD, Chevillet JR, Kroh EM, Ruf IK, Pritchard CC, Gibson DF, et al. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A. 2011; 108(12):5003-8. doi: 10.1073/pnas.1019055108 PMID: 21383194; PubMed Central PMCID: PMC3064324.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.12 , pp. 5003-5008
    • Arroyo, J.D.1    Chevillet, J.R.2    Kroh, E.M.3    Ruf, I.K.4    Pritchard, C.C.5    Gibson, D.F.6
  • 7
    • 84860390095 scopus 로고    scopus 로고
    • Circulating microRNAs: Promising breast cancer Biomarkers
    • 21345257
    • Heneghan H, Miller N, Kerin M. Circulating microRNAs: promising breast cancer Biomarkers. Breast Cancer Research. 2011; 13(1):402. doi: 10.1186/bcr2798 PMID: 21345257
    • (2011) Breast Cancer Research , vol.13 , Issue.1 , pp. 402
    • Heneghan, H.1    Miller, N.2    Kerin, M.3
  • 9
    • 84855502918 scopus 로고    scopus 로고
    • Exogenous plant MIR168a specifically targets mammalian LDLRAP1: Evidence of cross-kingdom regulation by microRNA
    • 21931358 Epub 2011/09/21
    • Zhang L, Hou D, Chen X, Li D, Zhu L, Zhang Y, et al. Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA. Cell Res. 2012; 22 (1):107-26. Epub 2011/09/21. doi: 10.1038/cr.2011.158 PMID: 21931358.
    • (2012) Cell Res. , vol.22 , Issue.1 , pp. 107-126
    • Zhang, L.1    Hou, D.2    Chen, X.3    Li, D.4    Zhu, L.5    Zhang, Y.6
  • 10
    • 84887497048 scopus 로고    scopus 로고
    • Lack of detectable oral bioavailability of plant microRNAs after feeding in mice
    • 24213763
    • Dickinson B, Zhang Y, Petrick JS, Heck G, Ivashuta S, Marshall WS. Lack of detectable oral bioavailability of plant microRNAs after feeding in mice. Nat Biotechnol. 2013; 31(11):965-7. doi: 10.1038/nbt.2737 PMID: 24213763.
    • (2013) Nat Biotechnol , vol.31 , Issue.11 , pp. 965-967
    • Dickinson, B.1    Zhang, Y.2    Petrick, J.S.3    Heck, G.4    Ivashuta, S.5    Marshall, W.S.6
  • 11
    • 84880852727 scopus 로고    scopus 로고
    • Ineffective delivery of diet-derived microRNAs to recipient animal organisms
    • 23669076
    • Snow JW, Hale A, Isaacs SK, Baggish AL, Chan SY. Ineffective delivery of diet-derived microRNAs to recipient animal organisms. RNA biology. 2013; 10(6). PMID: 23669076.
    • (2013) RNA Biology , vol.10 , Issue.6
    • Snow, J.W.1    Hale, A.2    Isaacs, S.K.3    Baggish, A.L.4    Chan, S.Y.5
  • 13
    • 84870930338 scopus 로고    scopus 로고
    • The complex exogenous RNA spectra in human plasma: An interface with human gut biota?
    • 23251414 PubMed Central PMCID: PMC3519536
    • Wang K, Li H, Yuan Y, Etheridge A, Zhou Y, Huang D, et al. The complex exogenous RNA spectra in human plasma: an interface with human gut biota? PLoS One. 2012; 7(12):e51009. doi: 10.1371/journal.pone.0051009 PMID: 23251414; PubMed Central PMCID: PMC3519536.
    • (2012) PLoS One , vol.7 , Issue.12 , pp. e51009
    • Wang, K.1    Li, H.2    Yuan, Y.3    Etheridge, A.4    Zhou, Y.5    Huang, D.6
  • 14
    • 84903218251 scopus 로고    scopus 로고
    • In silico identification of plant mirnas in mammalian breast milk exosomes - A small step forward?
    • 24933019 PubMed Central PMCID: PMC4059707
    • Lukasik A, Zielenkiewicz P. In Silico Identification of Plant miRNAs in Mammalian Breast Milk Exosomes-A Small Step Forward? PLoS One. 2014; 9(6):e99963. doi: 10.1371/journal.pone.0099963 PMID: 24933019; PubMed Central PMCID: PMC4059707.
    • (2014) PLoS One , vol.9 , Issue.6 , pp. e99963
    • Lukasik, A.1    Zielenkiewicz, P.2
  • 15
    • 84907255137 scopus 로고    scopus 로고
    • MicroRNAs are absorbed in biologically meaningful amounts from nutritionally relevant doses of cow milk and affect gene expression in peripheral blood mononuclear cells, HEK-293 kidney cell cultures, and mouse livers
    • 25122645
    • Baier SR, Nguyen C, Xie F, Wood JR, Zempleni J. MicroRNAs Are Absorbed in Biologically Meaningful Amounts from Nutritionally Relevant Doses of Cow Milk and Affect Gene Expression in Peripheral Blood Mononuclear Cells, HEK-293 Kidney Cell Cultures, and Mouse Livers. J Nutr. 2014; 144 (10):1495-500. doi: 10.3945/jn.114.196436 PMID: 25122645.
    • (2014) J Nutr. , vol.144 , Issue.10 , pp. 1495-1500
    • Baier, S.R.1    Nguyen, C.2    Xie, F.3    Wood, J.R.4    Zempleni, J.5
  • 16
    • 84964314461 scopus 로고    scopus 로고
    • Small RNAs from plants, bacteria and fungi within the order Hypocreales are ubiquitous in human plasma
    • 25344700 PubMed Central PMCID: PMC4230795
    • Beatty M, Guduric-Fuchs J, Brown E, Bridgett S, Chakravarthy U, Hogg RE, et al. Small RNAs from plants, bacteria and fungi within the order Hypocreales are ubiquitous in human plasma. BMC Genomics. 2014; 15:933. doi: 10.1186/1471-2164-15-933 PMID: 25344700; PubMed Central PMCID: PMC4230795.
    • (2014) BMC Genomics , vol.15 , pp. 933
    • Beatty, M.1    Guduric-Fuchs, J.2    Brown, E.3    Bridgett, S.4    Chakravarthy, U.5    Hogg, R.E.6
  • 17
    • 84880854859 scopus 로고    scopus 로고
    • Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs: Limited evidence for general uptake of dietary plant xenomiRs
    • 23770773 PubMed Central PMCID: PMC3849155
    • Witwer KW, McAlexander MA, Queen SE, Adams RJ. Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs: limited evidence for general uptake of dietary plant xenomiRs. RNA biology. 2013; 10(7):1080-6. doi: 10.4161/rna.25246 PMID: 23770773; PubMed Central PMCID: PMC3849155.
    • (2013) RNA Biology , vol.10 , Issue.7 , pp. 1080-1086
    • Witwer, K.W.1    McAlexander, M.A.2    Queen, S.E.3    Adams, R.J.4
  • 18
    • 84920274272 scopus 로고    scopus 로고
    • Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses
    • 25287280
    • Zhou Z, Li X, Liu J, Dong L, Chen Q, Liu J, et al. Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses. Cell Res. 2014; 25(1):39-49. doi: 10.1038/cr.2014.130 PMID: 25287280.
    • (2014) Cell Res. , vol.25 , Issue.1 , pp. 39-49
    • Zhou, Z.1    Li, X.2    Liu, J.3    Dong, L.4    Chen, Q.5    Liu, J.6
  • 19
    • 84926526961 scopus 로고    scopus 로고
    • Detection of dietary plant-based small RNAs in animals
    • 25721324
    • Yang J, Farmer LM, Agyekum AA, Hirschi KD. Detection of dietary plant-based small RNAs in animals. Cell Res. 2015; 25(4):517-20. doi: 10.1038/cr.2015.26 PMID: 25721324.
    • (2015) Cell Res. , vol.25 , Issue.4 , pp. 517-520
    • Yang, J.1    Farmer, L.M.2    Agyekum, A.A.3    Hirschi, K.D.4
  • 20
    • 84929309025 scopus 로고    scopus 로고
    • Dietary RNAs: New stories regarding oral delivery
    • 25942490
    • Yang J, Hirschi KD, Farmer LM. Dietary RNAs: New Stories Regarding Oral Delivery. Nutrients. 2015; 7(5):3184-99. doi: 10.3390/nu7053184 PMID: 25942490.
    • (2015) Nutrients , vol.7 , Issue.5 , pp. 3184-3199
    • Yang, J.1    Hirschi, K.D.2    Farmer, L.M.3
  • 22
    • 0016615492 scopus 로고
    • Mouse restraining chamber for tail-vein injection
    • 1186113
    • Furner RL, Mellett LB. Mouse restraining chamber for tail-vein injection. Laboratory animal science. 1975; 25(5):648. PMID: 1186113.
    • (1975) Laboratory Animal Science , vol.25 , Issue.5 , pp. 648
    • Furner, R.L.1    Mellett, L.B.2
  • 23
    • 0015134671 scopus 로고
    • A simple capillary tube method for the determination of the specific gravity of 25 and 50 micro l quantities of urine
    • 5118832 PubMed Central PMCID: PMC477119
    • Watts RH. A simple capillary tube method for the determination of the specific gravity of 25 and 50 micro l quantities of urine. Journal of clinical pathology. 1971; 24(7):667-8. PMID: 5118832; PubMed Central PMCID: PMC477119.
    • (1971) Journal of Clinical Pathology , vol.24 , Issue.7 , pp. 667-668
    • Watts, R.H.1
  • 24
    • 84892417146 scopus 로고    scopus 로고
    • A combination of Let-7d, Let-7g and Let-7i serves as a stable reference for normalization of serum microRNAs
    • 24223986 PubMed Central PMCID: PMC3818225
    • Chen X, Liang H, Guan D, Wang C, Hu X, Cui L, et al. A combination of Let-7d, Let-7g and Let-7i serves as a stable reference for normalization of serum microRNAs. PLoS One. 2013; 8(11):e79652. doi: 10.1371/journal.pone.0079652 PMID: 24223986; PubMed Central PMCID: PMC3818225.
    • (2013) PLoS One , vol.8 , Issue.11 , pp. e79652
    • Chen, X.1    Liang, H.2    Guan, D.3    Wang, C.4    Hu, X.5    Cui, L.6
  • 25
    • 0026067071 scopus 로고
    • A simple and efficient method for direct cloning of PCR products using ddTtailed vectors
    • 2020554 PubMed Central PMCID: PMC333802
    • Holton TA, Graham MW. A simple and efficient method for direct cloning of PCR products using ddTtailed vectors. Nucleic Acids Research. 1991; 19(5):1156. PMID: 2020554; PubMed Central PMCID: PMC333802.
    • (1991) Nucleic Acids Research , vol.19 , Issue.5 , pp. 1156
    • Holton, T.A.1    Graham, M.W.2
  • 26
    • 79952855316 scopus 로고    scopus 로고
    • Depletion of murine intestinal microbiota: Effects on gut mucosa and epithelial gene expression
    • 21445311 PubMed Central PMCID: PMC3061881
    • Reikvam DH, Erofeev A, Sandvik A, Grcic V, Jahnsen FL, Gaustad P, et al. Depletion of murine intestinal microbiota: effects on gut mucosa and epithelial gene expression. PLoS One. 2011; 6(3):e17996. doi: 10.1371/journal.pone.0017996 PMID: 21445311; PubMed Central PMCID: PMC3061881.
    • (2011) PLoS One , vol.6 , Issue.3 , pp. e17996
    • Reikvam, D.H.1    Erofeev, A.2    Sandvik, A.3    Grcic, V.4    Jahnsen, F.L.5    Gaustad, P.6
  • 27
    • 53349177819 scopus 로고    scopus 로고
    • Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases
    • 18766170
    • Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 2008; 18(10):997-1006. doi: 10.1038/cr.2008.282 PMID: 18766170.
    • (2008) Cell Res. , vol.18 , Issue.10 , pp. 997-1006
    • Chen, X.1    Ba, Y.2    Ma, L.3    Cai, X.4    Yin, Y.5    Wang, K.6
  • 28
    • 78149409316 scopus 로고    scopus 로고
    • Export of microRNAs and microRNA-protective protein by mammalian cells
    • 20615901 Epub 2010/07/10. PubMed Central PMCID: PMC2978372
    • Wang K, Zhang S, Weber J, Baxter D, Galas DJ. Export of microRNAs and microRNA-protective protein by mammalian cells. Nucleic Acids Research. 2010; 38(20):7248-59. Epub 2010/07/10. doi: 10.1093/nar/gkq601 PMID: 20615901; PubMed Central PMCID: PMC2978372.
    • (2010) Nucleic Acids Research , vol.38 , Issue.20 , pp. 7248-7259
    • Wang, K.1    Zhang, S.2    Weber, J.3    Baxter, D.4    Galas, D.J.5
  • 30
    • 84863485635 scopus 로고    scopus 로고
    • In vivo gene delivery by nonviral vectors: Overcoming hurdles?
    • 22525514 PubMed Central PMCID: PMC3392980
    • Zhang Y, Satterlee A, Huang L. In vivo gene delivery by nonviral vectors: overcoming hurdles? Molecular therapy: the journal of the American Society of Gene Therapy. 2012; 20(7):1298-304. doi: 10.1038/mt.2012.79 PMID: 22525514; PubMed Central PMCID: PMC3392980.
    • (2012) Molecular Therapy: The Journal of the American Society of Gene Therapy , vol.20 , Issue.7 , pp. 1298-1304
    • Zhang, Y.1    Satterlee, A.2    Huang, L.3
  • 31
    • 80051812841 scopus 로고    scopus 로고
    • The remarkable capacity for gut microbial and host interactions
    • 21646867 PubMed Central PMCID: PMC3225776
    • Nagy-Szakal D, Kellermayer R. The remarkable capacity for gut microbial and host interactions. Gut microbes. 2011; 2(3):178-82. PMID: 21646867; PubMed Central PMCID: PMC3225776.
    • (2011) Gut Microbes , vol.2 , Issue.3 , pp. 178-182
    • Nagy-Szakal, D.1    Kellermayer, R.2
  • 32
    • 62549129560 scopus 로고    scopus 로고
    • Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
    • 19202076 PubMed Central PMCID: PMC2651297
    • Brandl K, Rutschmann S, Li X, Du X, Xiao N, Schnabl B, et al. Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response. Proc Natl Acad Sci U S A. 2009; 106(9):3300-5. doi: 10.1073/pnas.0813036106 PMID: 19202076; PubMed Central PMCID: PMC2651297.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.9 , pp. 3300-3305
    • Brandl, K.1    Rutschmann, S.2    Li, X.3    Du, X.4    Xiao, N.5    Schnabl, B.6
  • 33
    • 84896087919 scopus 로고    scopus 로고
    • Changes in the mucus barrier during cisplatin-induced intestinal mucositis in rats
    • 24455680 PubMed Central PMCID: PMC3884955
    • Yamamoto H, Ishihara K, Takeda Y, Koizumi W, Ichikawa T. Changes in the mucus barrier during cisplatin-induced intestinal mucositis in rats. BioMed research international. 2013; 2013:276186. doi: 10.1155/2013/276186 PMID: 24455680; PubMed Central PMCID: PMC3884955.
    • (2013) BioMed Research International , vol.2013 , pp. 276186
    • Yamamoto, H.1    Ishihara, K.2    Takeda, Y.3    Koizumi, W.4    Ichikawa, T.5
  • 34
    • 84916918525 scopus 로고    scopus 로고
    • Diet-responsive mammalian miRNAs are likely endogenous
    • 25332488
    • Witwer KW. Diet-responsive mammalian miRNAs are likely endogenous. J Nutr. 2014; 144(11):1880-1. doi: 10.3945/jn.114.202523 PMID: 25332488.
    • (2014) J Nutr. , vol.144 , Issue.11 , pp. 1880-1881
    • Witwer, K.W.1
  • 35
    • 84928818473 scopus 로고    scopus 로고
    • Free extracellular miRNA Functionally targets cells by transfecting exosomes from their companion cells
    • 25923429 PubMed Central PMCID: PMC4414541
    • Bryniarski K, Ptak W, Martin E, Nazimek K, Szczepanik M, Sanak M, et al. Free Extracellular miRNA Functionally Targets Cells by Transfecting Exosomes from Their Companion Cells. PLoS One. 2015; 10(4):e0122991. doi: 10.1371/journal.pone.0122991 PMID: 25923429; PubMed Central PMCID: PMC4414541.
    • (2015) PLoS One , vol.10 , Issue.4 , pp. e0122991
    • Bryniarski, K.1    Ptak, W.2    Martin, E.3    Nazimek, K.4    Szczepanik, M.5    Sanak, M.6
  • 36
    • 38949111331 scopus 로고    scopus 로고
    • Stability and delivery of RNA via the gastrointestinal tract
    • 18220548
    • Jain KK. Stability and delivery of RNA via the gastrointestinal tract. Current drug delivery. 2008; 5 (1):27-31. PMID: 18220548.
    • (2008) Current Drug Delivery , vol.5 , Issue.1 , pp. 27-31
    • Jain, K.K.1
  • 37
    • 84892828465 scopus 로고    scopus 로고
    • Diet rapidly and reproducibly alters the human gut microbiome
    • 24336217
    • David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014; 505(7484):559-63. doi: 10.1038/nature12820 PMID: 24336217.
    • (2014) Nature , vol.505 , Issue.7484 , pp. 559-563
    • David, L.A.1    Maurice, C.F.2    Carmody, R.N.3    Gootenberg, D.B.4    Button, J.E.5    Wolfe, B.E.6
  • 39
    • 79955518664 scopus 로고    scopus 로고
    • Regulation of tight junction permeability by intestinal bacteria and dietary components
    • 21430248
    • Ulluwishewa D, Anderson RC, McNabb WC, Moughan PJ, Wells JM, Roy NC. Regulation of tight junction permeability by intestinal bacteria and dietary components. J Nutr. 2011; 141(5):769-76. doi: 10.3945/jn.110.135657 PMID: 21430248.
    • (2011) J Nutr. , vol.141 , Issue.5 , pp. 769-776
    • Ulluwishewa, D.1    Anderson, R.C.2    McNabb, W.C.3    Moughan, P.J.4    Wells, J.M.5    Roy, N.C.6
  • 40
    • 84903545653 scopus 로고    scopus 로고
    • Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles
    • 24842810
    • Mu J, Zhuang X, Wang Q, Jiang H, Deng ZB, Wang B, et al. Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles. Mol Nutr Food Res. 2014; 58(7):1561-73. doi: 10.1002/mnfr.201300729 PMID: 24842810.
    • (2014) Mol Nutr Food Res. , vol.58 , Issue.7 , pp. 1561-1573
    • Mu, J.1    Zhuang, X.2    Wang, Q.3    Jiang, H.4    Deng, Z.B.5    Wang, B.6
  • 41
    • 84883496908 scopus 로고    scopus 로고
    • Circulating miRNAs: Cell-cell communication function?
    • 23825476 PubMed Central PMCID: PMC3695387
    • Turchinovich A, Samatov TR, Tonevitsky AG, Burwinkel B. Circulating miRNAs: cell-cell communication function? Frontiers in genetics. 2013; 4:119. doi: 10.3389/fgene.2013.00119 PMID: 23825476; PubMed Central PMCID: PMC3695387.
    • (2013) Frontiers in Genetics , vol.4 , pp. 119
    • Turchinovich, A.1    Samatov, T.R.2    Tonevitsky, A.G.3    Burwinkel, B.4
  • 42
    • 84926525118 scopus 로고    scopus 로고
    • A novel chemopreventive strategy based on therapeutic microRNAs produced in plants
    • 25721325
    • Mlotshwa S, Pruss GJ, MacArthur JL, Endres MW, Davis C, Hofseth LJ, et al. A novel chemopreventive strategy based on therapeutic microRNAs produced in plants. Cell Res. 2015; 25(4):521-4. doi: 10.1038/cr.2015.25 PMID: 25721325.
    • (2015) Cell Res. , vol.25 , Issue.4 , pp. 521-524
    • Mlotshwa, S.1    Pruss, G.J.2    MacArthur, J.L.3    Endres, M.W.4    Davis, C.5    Hofseth, L.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.