Lack of detectable oral bioavailability of plant microRNAs after feeding in mice

Nature Biotechnology

Volumn 31, Issue 11, 2013, Pages 965-967

  Dickinson, Brent ^a   Zhang, Yuanji ^b   Petrick, Jay S ^b   Heck, Gregory ^b   Ivashuta, Sergey ^b   Marshall, William S ^a  

^a MiRagen Therapeutics   (United States)

^b MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; DOUBLE STRANDED RNA; LDL RECEPTOR ADAPTOR PROTEIN 1; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MICRORNA; NUCLEIC ACID; PLANT MICRORNA; PLANT RNA; RNA LIGASE; SOYBEAN OIL; STARCH; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTIFACT; BLOOD SAMPLING; CAENORHABDITIS; CHOLESTEROL BLOOD LEVEL; DIET; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG STABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEEDING; FOOD INTAKE; GASTROINTESTINAL TRACT; GENE CONTROL; GENE SILENCING; GRAIN; LETTER; LIPOPROTEIN BLOOD LEVEL; LIVER; MAMMAL; MOUSE; NONHUMAN; NUTRITION; PEPTIDE LIBRARY; PLANT; PRIORITY JOURNAL; QUALITY CONTROL; RICE; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MICRORNAS; ORYZA SATIVA; RNA, PLANT;

EID: 84887497048     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2737     Document Type: Letter

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