Clinical decision aids for chest pain in the emergency department: Identifying low-risk patients

Open Access Emergency Medicine

Volumn 7, Issue , 2015, Pages 85-92

  Alley, William ^a   Mahler, Simon A ^a  

^a WAKE FOREST BAPTIST HEALTH   (United States)

Author keywords

Acute coronary syndrome; Chest pain; Decision aid; Risk score

Indexed keywords

FIBRINOLYTIC AGENT; TROPONIN;

ACUTE CORONARY SYNDROME; BLOOD CLOT LYSIS; CLINICAL ASSESSMENT TOOL; CLINICAL DECISION MAKING; CLINICAL TRIAL (TOPIC); COHORT ANALYSIS; EMERGENCY WARD; GLOBAL REGISTRY OF ACUTE CORONARY EVENTS SCORE; HEALTH CARE NEED; HEART INFARCTION; HISTORY ELECTROCARDIOGRAM AGE RISK FACTORS TROPONIN SCORE; HUMAN; LOW RISK PATIENT; MODIFIED THROMBOLYSIS IN MYOCARDIAL INFARCTION RISK SCORE; NORTH AMERICAN CHEST PAIN RULE; PROGNOSIS; RETROSPECTIVE STUDY; REVIEW; RISK ASSESSMENT; SCORING SYSTEM; THORAX PAIN; THROMBOLYSIS IN MYOCARDIAL INFARCTION RISK SCORE; VALIDATION STUDY;

EID: 84947439441     PISSN: None     EISSN: 11791500     Source Type: Journal    
DOI: 10.2147/OAEM.S71282     Document Type: Review

References (34)

1. Bhuiya FA, Pitts SR, McCaig LF. Emergency department visits for chest pain and abdominal pain: United States, 1999-2008. NCHS Data Brief. 2010;(43):1-8.
2. Pope JH, Aufderheide TP, Ruthazer R, et al. Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J Med. 2000;342(16):1163-1170.
3. Kline JA, Johnson CL, Pollack CV Jr, et al. Pretest probability assessment derived from attribute matching. BMC Med Inform Decis Mak. 2005;5:26.
4. Than M, Herbert M, Flaws D, et al. What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the Emergency Department? A clinical survey. Int J Cardiol. 2013;166(3): 752-754.
5. Antman EM, Cohen M, Bernink PM, et al. The TIMI risk score for unstable angina/non-ST elevation MI: a method for prognostication and therapeutic decision making. JAMA. 2000;284(7):835-842.
6. Antman EM, McCabe CH, Gurfinkel EP, et al. Enoxaparin prevents death and cardiac ischemic events in unstable angina/non-Q-wave myocardial infarction: results of the thrombolysis in myocardial infarction (TIMI) 11B trial. Circulation. 1999;100:1593-1601.
7. Cohen M, Demers C, Gurfinkel EP, et al. A comparison of low- molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. N Engl J Med. 1997;337:447-452.
8. Pollack CV Jr, Sites FD, Shofer FS, et al. Application of the TIMI risk score for unstable angina and non-ST elevation acute coronary syndrome to an unselected emergency department chest pain population. Acad Emerg Med. 2006;13:13-18.
9. Hess EP, Agarwal D, Chandra S, et al. Diagnostic accuracy of the TIMI risk score in patients with chest pain in the emergency department: a meta-analysis. CMAJ. 2010;182(10):1039-1044.
10. Jaffery Z, Hudson MP, Jacobsen G, et al. Modified thrombolysis in myocardial infarction (TIMI) risk score to risk stratify patients in the emergency department with possible acute coronary syndrome. J Thromb Thrombolysis. 2007;24(2):137-144.
11. GRACE Investigators. Rationale and design of the GRACE (Global Registry of Acute Coronary Events) project: a multinational registry of patients hospitalized with acute coronary syndromes. Am Heart J. 2001;141:190-199.
12. Granger CB, Goldberg RJ, Dabbous O, et al. Predictors of hospital mortality in the global registry of acute coronary events. Arch Intern Med. 2003;163(19):2345-2353.
13. Cho L, Bhatt DL, Marso SP, et al. An invasive strategy is associated with decreased mortality in patients with unstable angina and non-ST-elevation myocardial infarction: GUSTO IIb trial. Am J Med. 2003; 114(2):106-111.
14. Eagle KA, Lim MJ, Dabbous OH, et al. A validated prediction model for all forms of acute coronary syndrome: estimating the risk of 6-month postdischarge death in an international registry. JAMA. 2004;291(22):2727-2733.
15. Lyon R, Morris AC, Caesar D, et al. Chest pain presenting to the Emergency Department - to stratify risk with GRACE or TIMI? Resuscitation. 2007;74(1):90-93.
16. Than M, Cullen L, Reid CM, et al. A 2-h diagnostic protocol to assess patients with chest pain symptoms in the Asia-Pacific region (ASPECT): a prospective observational validation study. Lancet. 2011;377: 1077-1084.
17. Collinson PO, Gaze DC, Thokala P, et al. Randomised assessment of treatment using panel assay of cardiac markers - contemporary biomarker evaluation (RATPAC CBE). Health Technol Assess. 2013; 17(15):1-122.
18. Body R. Acute MI: triple-markers resurrected or Bayesian dice? Lancet. 2011;377:1049-1050.
19. Than M, Cullen L, Aldous S, et al. 2-Hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: the ADAPT trial. J Am Coll Cardiol. 2012;59:2091-2098.
20. Than M, Aldous S, Lord SJ, et al. A 2-hour diagnostic protocol for possible cardiac chest pain in the emergency department: a randomized clinical trial. JAMA Intern Med. 2014;174:51-58.
21. Cullen L, Mueller C, Parsonage WA, et al. Validation of high-sensitivity troponin I in a 2-hour diagnostic strategy to assess 30-day outcomes in emergency department patients with possible acute coronary syndrome. J Am Coll Cardiol. 2013;62(14):1242-1249.
22. Mahler SA, Miller CD, Litt HI, et al. Performance of the 2-hour accelerated diagnostic protocol within the American College of Radiology Imaging Network PA 4005 cohort. Acad Emerg Med. 2015;22:452-460.
23. Litt HI, Gatsonis C, Snyder B, et al. CT angiography for safe discharge of patients with possible acute coronary syndromes. N Engl J Med. 2012;366:1393-1403.
24. Hess EP, Brison RJ, Perry JJ, et al. Development of a clinical prediction rule for 30-day cardiac events in emergency department patients with chest pain and possible acute coronary syndrome. Ann Emerg Med. 2012;59:115-125.
25. Mahler SA, Miller CD, Hollander JE, et al. Identifying patients for early discharge: performance of decision rules among patients with acute chest pain. Int J Cardiol. 2013;168:795-802.
26. Collin MJ, Weisenthal B, Walsh KM, et al. Young patients with chest pain: 1-year outcomes. Am J Emerg Med. 2011;29(3):265-270.
27. Six AJ, Backus BE, Kelder JC. Chest pain in the emergency room: value of the heart score. Neth Heart J. 2008;16(6):191-196.
28. Backus BE, Six AJ, Kelder JC, et al. Chest pain in the emergency room: a multicenter validation of the HEART score. Crit Pathw Cardiol. 2010;9:164-169.
29. Backus BE, Six AJ, Kelder JC, et al. A prospective validation of the HEART score for chest pain patients at the emergency department. Int J Cardiol. 2013;168:2153-2158.
30. Six AJ, Cullen L, Backus BE, et al. The HEART score for the assessment of patients with chest pain in the emergency department: a multinational validation study. Crit Pathw Cardiol. 2013;12:121-126.
31. Mahler SA, Hiestand BC, Goff DC, et al. Can the HEART score safely reduce stress testing and cardiac imaging in patients at low risk for major adverse cardiac events? Crit Pathw Cardiol. 2011;10:128-133.
32. Mahler SA, Riley RF, Hiestand BC, et al. The HEART pathway randomized trial: identifying emergency department patients with acute chest pain for early discharge. Circ Cardiovasc Qual Outcomes. 2015;8(2):195-203.
33. Cullen L, Greenslade JH, Than M, et al. The new Vancouver Chest Pain Rule using troponin as the only biomarker: an external validation study. Am J Emerg Med. 2014;32(2):129-134.
34. Than M, Flaws D, Sanders S, et al. Development and validation of the Emergency Department Assessment of Chest Pain Score and 2 h accelerated diagnostic protocol. Emerg Med Australas. 2014;26(1):34-44.