Factors associated with severe leptospirosis, Martinique, 2010–2013

Emerging Infectious Diseases

Volumn 21, Issue 12, 2015, Pages 2221-2224

  Hochedez, Patrick ^a,b,c   Theodose, Rafaelle ^a,b,c   Olive, Claude ^a,b,c   Bourhy, Pascale ^d   Hurtrel, Guillaume ^a   Vignier, Nicolas ^a,e   Mehdaoui, Hossein ^a   Valentino, Ruddy ^a   Martinez, Roland ^f   Delord, Jean Marie ^g   Herrmann, Cécile ^b,c,h   Lamaury, Isabelle ^b,c,h   Césaire, Raymond ^a,b,c   Picardeau, Mathieu ^d   Cabié, André ^a,i  

^a CENTRE HOSPITALIER UNIVERSITAIRE DE FORT DE FRANCE   (France)

^b UNIVERSITÉ DES ANTILLES ET DE LA GUYANE   (France)

^c Institut Pasteur ^*  (Guadeloupe)

^d INSTITUT PASTEUR   (France)

^e AVICENNE HOSPITAL   (France)

^f Centre Hospitalier de Trinité   (Martinique)

^g Centre Hospitalier du Lamentin   (Martinique)

^h Ctr Hosp Univ de Pointe a Pitre   (Guadeloupe)

ⁱ INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGGLUTINATION TEST; ANURIA; ARTICLE; AUSCULTATION; BLOOD SAMPLING; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE SEVERITY; DNA EXTRACTION; FEMALE; HUMAN; HYPOTENSION; JAUNDICE; LEPTOSPIRA INTERROGANS SEROVAR ICTEROHAEMORRHAGIAE; LEPTOSPIROSIS; MAJOR CLINICAL STUDY; MALE; MARTINIQUE; OLIGURIA; POLYMERASE CHAIN REACTION; PROTHROMBIN TIME; THROMBOCYTOPENIA; ANIMAL; BLOOD; DOG; DOG DISEASES; EPIDEMIC; GENETICS; MIDDLE AGED; PATHOLOGY; ZOONOSES;

ADULT; ANIMALS; DISEASE OUTBREAKS; DOG DISEASES; DOGS; FEMALE; HUMANS; LEPTOSPIROSIS; MALE; MARTINIQUE; MIDDLE AGED; ZOONOSES;

EID: 84947426998     PISSN: 10806040     EISSN: 10806059     Source Type: Journal    
DOI: 10.3201/eid2112.141099     Document Type: Article

References (15)

1. Levett PN. Leptospirosis. Clin Microbiol Rev. 2001;14:296–326. http://dx.doi.org/10.1128/CMR.14.2.296-326.2001
2. Bharti AR, Nally JE, Ricaldi JN, Matthias MA, Diaz MM, Lovett MA, et al. Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis. 2003;3:757–71. http://dx.doi.org/10.1016/S1473-3099(03)00830-2
3. Ko AI, Goarant C, Picardeau M. Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen. Nat Rev Microbiol. 2009;7:736–47. http://dx.doi.org/10.1038/nrmicro2208
4. Bourhy P, Herrmann Storck C, Theodose R, Olive C, Nicolas M, Hochedez P, et al. Serovar diversity of pathogenic Leptospira circulating in the French West Indies. PLoS Negl Trop Dis. 2013;7:e2114. http://dx.doi.org/10.1371/journal.pntd.0002114
5. Truccolo J, Serais O, Merien F, Perolat P. Following the course of human leptospirosis: evidence of a critical threshold for the vital prognosis using a quantitative PCR assay. FEMS Microbiol Lett. 2001;204:317–21. http://dx.doi.org/10.1111/j.1574-6968.2001.tb10904.x
6. World Health Organization. Human leptospirosis: guidance for diagnosis, surveillance and control. Geneva: The Organization; 2003. p. 9–16
7. Merien F, Portnoi D, Bourhy P, Charavay F, Berlioz-Arthaud A, Baranton G. A rapid and quantitative method for the detection of Leptospira species in human leptospirosis. FEMS Microbiol Lett. 2005;249:139–47. http://dx.doi.org/10.1016/j.femsle.2005.06.011
8. Hochedez P, Escher M, Decoussy H, Pasgrimaud L, Martinez R, Rosine J, et al. Outbreak of leptospirosis among canyoning participants, Martinique, 2011. Euro Surveill. 2013;18:20472.
9. Bourhy P, Bremont S, Zinini F, Giry C, Picardeau M. Comparison of real-time PCR assays for detection of pathogenic Leptospira spp. in blood and identification of variations in target sequences. J Clin Microbiol. 2011;49:2154–60. http://dx.doi.org/10.1128/JCM.02452-10
10. Bourhy P, Collet L, Clement S, Huerre M, Ave P, Giry C, et al. Isolation and characterization of new Leptospira genotypes from patients in Mayotte (Indian Ocean). PLoS Negl Trop Dis. 2010;4:e724. http://dx.doi.org/10.1371/journal.pntd.0000724
11. Mérien F, Amouriaux P, Perolat P, Baranton G, Saint Girons I. Polymerase chain reaction for detection of Leptospira spp. in clinical samples. J Clin Microbiol. 1992;30:2219–24.
12. Herrmann-Storck C, Saint-Louis M, Foucand T, Lamaury I, Deloumeaux J, Baranton G, et al. Severe leptospirosis in hospitalized patients, Guadeloupe. Emerg Infect Dis. 2010;16: 331–4. http://dx.doi.org/10.3201/eid1602.090139
13. Tubiana S, Mikulski M, Becam J, Lacassin F, Lefevre P, Gourinat AC, et al. Risk factors and predictors of severe leptospirosis in New Caledonia. PLoS Negl Trop Dis. 2013;7:e1991. PLoS Negl Trop Dis. 2013;7:e1991. http://dx.doi.org/10.1371/journal.pntd.0001991
14. Merien F, Baranton G, Perolat P. Comparison of polymerase chain reaction with microagglutination test and culture for diagnosis of leptospirosis. J Infect Dis. 1995;172:281–5. http://dx.doi.org/10.1093/infdis/172.1.281
15. Agampodi SB, Moreno AC, Vinetz JM, Matthias MA. Utility and limitations of direct multi-locus sequence typing on qPCR-positive blood to determine infecting Leptospira strain. Am J Trop Med Hyg. 2013;88:184–5. http://dx.doi.org/10.4269/ajtmh.2012.12-0526