Toxicity of 100 nm zinc oxide nanoparticles: A report of 90-day repeated oral administration in Sprague Dawley rats

International Journal of Nanomedicine

Volumn 9, Issue , 2014, Pages 109-126

  Kim, Yu Ri ^a   Park, Jong Il ^b   Lee, Eun Jeong ^a   Park, Sung Ha ^c   Seong, Nak Won ^b   Kim, Jun Ho ^b   Kim, Geon Yong ^b   Meang, Eun Ho ^b   Hong, Jeong Sup ^b   Kim, Su Hyon ^b   Koh, Sang Bum ^b   Kim, Min Seok ^b   Kim, Cheol Su ^d   Kim, Soo Ki ^d   Son, Sang Wook ^e   Seo, Young Rok ^f   Kang, Boo Hyon ^g   Han, Beom Seok ^h   An, Seong Soo A ⁱ   Yun, Hyo In ⁱ   Kim, Meyoung Kon ^a   more..

^a Korea University   (South Korea)

^b Korea Testing and Research Institute   (South Korea)

^c University of Bath   (United Kingdom)

^d Yonsei University Wonju College of Medicine   (South Korea)

^e Dongguk University   (South Korea)

^f Chemon Inc   (South Korea)

^g Hoseo University   (South Korea)

^h Gachon University College of Medicine   (South Korea)

ⁱ Chungnam National University   (South Korea)

Author keywords

90 day oral dose toxicity; No observed adverse effect level; Surface charge; Zinc oxide nanoparticles

Indexed keywords

ZINC OXIDE NANOPARTICLE; METAL NANOPARTICLE; ZINC OXIDE;

ACCLIMATIZATION; ANEMIA; ANIMAL EXPERIMENT; ARTICLE; AUTOPSY; BIOCHEMICAL ANALYSIS; BLOOD EXAMINATION; BODY WEIGHT; CONTROLLED STUDY; ERYTHROCYTE COUNT; EYE; FEMALE; FLUID INTAKE; FOOD INTAKE; HISTOPATHOLOGY; HYDRODYNAMICS; LEUKOCYTE COUNT; MALE; MORPHOLOGY; MORTALITY; NONHUMAN; ORAL TOXICITY; ORGAN WEIGHT; PANCREAS; PARTICLE SIZE; PROSTATE; RAT; STOMACH; SURFACE CHARGE; TESTIS WEIGHT; TOXICITY TESTING; URINALYSIS; VISUAL SYSTEM EXAMINATION; ZETA POTENTIAL; ANIMAL; CHEMISTRY; DRUG EFFECTS; ORAL DRUG ADMINISTRATION; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ADMINISTRATION, ORAL; ANIMALS; FEMALE; MALE; METAL NANOPARTICLES; PANCREAS; RATS, SPRAGUE-DAWLEY; STOMACH; TISSUE DISTRIBUTION; TOXICITY TESTS; ZINC OXIDE;

EID: 84947419390     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S57928     Document Type: Article

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